adamantane has been researched along with Fibrosis in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 8 (72.73) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Z; Dong, W; Fu, R; Li, K; Li, X; Li, Y; Ma, X; Tian, X; Wang, J; Wang, L; Yao, T; Zhang, Y; Zhao, W | 1 |
| Bajaj, M; Birnbaum, Y; Perez-Polo, JR; Yang, HC; Ye, Y | 1 |
| Aroor, AR; Bender, SB; Brown, SM; Chandrasekar, B; Cleeton, HM; DeMarco, VG; Khan, M; Meininger, GA; Meuth, AI; Nistala, R; Smith, CE; Sowers, JR | 1 |
| Cavadas, C; Cunha-Santos, J; Leal, H; Marques, AP; Pereira de Almeida, L; Rosmaninho-Salgado, J; Sousa-Ferreira, L | 1 |
| Cao, J; Deng, X; Di, Y; Gao, J; Guo, Y; Huang, X; Liu, L; Sun, S | 1 |
| Arisi, MF; Atluri, P; Burdick, JA; Chen, CW; Chung, JJ; Gaffey, AC; Gordon, J; Han, J; Kim, ST; Li, E; Tran, Z; Wang, LL; Zaman, S | 1 |
| Asakura, M; Asano, Y; Asanuma, H; Ishibashi-Ueda, H; Ito, S; Kitakaze, M; Liao, Y; Min, KD; Minamino, T; Mochizuki, N; Sanada, S; Shindo, K; Takahashi, A; Takashima, S; Yamazaki, S; Yan, Y | 1 |
| Apaijai, N; Chattipakorn, N; Chattipakorn, SC; Inthachai, T; Kumfu, S; Lekawanvijit, S; Pongkan, W | 1 |
| Gangadharan Komala, M; Gross, S; Panchapakesan, U; Pollock, C; Zaky, A | 1 |
| Kimoto, N; Kitayama, T; Kunori, S; Sakai, M; Uchii, M | 1 |
| Cheng, Q; de Gasparo, M; Law, PK; Leung, PS | 1 |
11 other study(ies) available for adamantane and Fibrosis
| Article | Year |
|---|---|
Profibrotic mechanisms of DPP8 and DPP9 highly expressed in the proximal renal tubule epithelial cells.
Topics: Adamantane; Animals; Blotting, Western; Case-Control Studies; Cell Line; Dipeptidases; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Epithelial-Mesenchymal Transition; Fibrosis; Fluorescent Antibody Technique; Humans; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Renal Insufficiency, Chronic | 2021 |
SGLT-2 Inhibition with Dapagliflozin Reduces the Activation of the Nlrp3/ASC Inflammasome and Attenuates the Development of Diabetic Cardiomyopathy in Mice with Type 2 Diabetes. Further Augmentation of the Effects with Saxagliptin, a DPP4 Inhibitor.
Topics: Adamantane; AMP-Activated Protein Kinases; Animals; Apoptosis; Benzhydryl Compounds; CARD Signaling Adaptor Proteins; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Dipeptides; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Drug Therapy, Combination; Fibroblasts; Fibrosis; Glucosides; Hypoglycemic Agents; Inflammasomes; Inflammation Mediators; Kidney Tubules, Proximal; Male; Mice, Inbred C57BL; Mice, Obese; Myocytes, Cardiac; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Stroke Volume; Time Factors; Ventricular Function, Left | 2017 |
Dipeptidyl Peptidase-4 Inhibition With Saxagliptin Ameliorates Angiotensin II-Induced Cardiac Diastolic Dysfunction in Male Mice.
Topics: Adamantane; Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; CD4-Positive T-Lymphocytes; CD8 Antigens; Diastole; Dipeptides; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Echocardiography; Fibrosis; Gene Expression; Heart; Inflammation; Interleukin-17; Interleukin-18; Lymphocytes; Macrophages; Male; Mice; Proto-Oncogene Proteins c-jun; Signal Transduction; Vascular Stiffness; Vasoconstrictor Agents | 2017 |
Dipeptidyl peptidase IV (DPP-IV) inhibition prevents fibrosis in adipose tissue of obese mice.
Topics: 3T3-L1 Cells; Adamantane; Adipocytes; Adipose Tissue, White; Animals; Blood Glucose; Collagen; Diet, High-Fat; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Extracellular Matrix; Fibrosis; Hypolipidemic Agents; Leptin; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Neuropeptide Y; Nitriles; Obesity; Pyrrolidines; Receptors, Neuropeptide Y; RNA Interference; RNA, Small Interfering; Transforming Growth Factor beta1; Vildagliptin | 2018 |
Improved endogenous epoxyeicosatrienoic acid production mends heart function via increased PGC 1α-mitochondrial functions in metabolic syndrome.
Topics: Adamantane; Adenosine Triphosphate; Animals; Cardiotonic Agents; Disease Models, Animal; Endothelium; Fibrosis; Heme Oxygenase-1; Hemodynamics; Hypertrophy; Inflammation Mediators; Lauric Acids; Male; Metabolic Syndrome; Mitochondria; Myocardium; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats, Wistar; Up-Regulation | 2018 |
Delayed delivery of endothelial progenitor cell-derived extracellular vesicles via shear thinning gel improves postinfarct hemodynamics.
Topics: Adamantane; Animals; beta-Cyclodextrins; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Endothelial Progenitor Cells; Extracellular Vesicles; Fibrosis; Gels; Hemodynamics; Human Umbilical Vein Endothelial Cells; Humans; Hyaluronic Acid; Inflammation Mediators; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; Rats, Wistar; Time Factors; Time-to-Treatment | 2020 |
Dipeptidyl-peptidase IV inhibition improves pathophysiology of heart failure and increases survival rate in pressure-overloaded mice.
Topics: Adamantane; Animals; Apoptosis; Blood Pressure; Blotting, Western; Dipeptidyl-Peptidase IV Inhibitors; Electrocardiography; Enzyme-Linked Immunosorbent Assay; Fibrosis; Glucagon-Like Peptide 1; Glucose Tolerance Test; Heart Failure; Heart Rate; Hemodynamics; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Nitriles; Organ Size; Pyrrolidines; Real-Time Polymerase Chain Reaction; Survival; Vildagliptin | 2013 |
Dipeptidyl peptidase-4 inhibitor improves cardiac function by attenuating adverse cardiac remodelling in rats with chronic myocardial infarction.
Topics: Adamantane; Angiotensin-Converting Enzyme Inhibitors; Animals; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Enalapril; Fibrosis; Heart Rate; Hypoglycemic Agents; Male; Metformin; Myocardial Infarction; Myocardium; Nitriles; Oxidative Stress; Pyrrolidines; Rats, Wistar; Recovery of Function; Signal Transduction; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling; Vildagliptin | 2015 |
Saxagliptin reduces renal tubulointerstitial inflammation, hypertrophy and fibrosis in diabetes.
Topics: Adamantane; Albuminuria; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Dipeptides; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Fibronectins; Fibrosis; Glomerulonephritis; Hypertrophy; Insulin; Kidney; Male; Mice, Knockout; Nephritis, Interstitial; Nitric Oxide Synthase Type III; Phosphorylation; Signal Transduction; Smad2 Protein; Smad3 Protein; Streptozocin; Transcription Factor RelA; Transforming Growth Factor beta | 2016 |
Glucose-independent renoprotective mechanisms of the tissue dipeptidyl peptidase-4 inhibitor, saxagliptin, in Dahl salt-sensitive hypertensive rats.
Topics: Adamantane; Animals; Blood Glucose; Blood Pressure; Creatinine; Cytoprotection; Dipeptides; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Fibrosis; Gene Expression Regulation; Hypertension; Kidney; Kidney Glomerulus; Kidney Tubules; Male; Myocardium; Organ Size; Rats; Rats, Inbred Dahl; Sodium | 2016 |
Combination of the dipeptidyl peptidase IV inhibitor LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] with the angiotensin II type 1 receptor antagonist valsartan [N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl]
Topics: Adamantane; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Cell Proliferation; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Synergism; Drug Therapy, Combination; Fibrosis; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Pyrrolidines; Reactive Oxygen Species; Tetrazoles; Valine; Valsartan | 2008 |