Page last updated: 2024-08-21

adamantane and Fascioliasis

adamantane has been researched along with Fascioliasis in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bosco, A; Cringoli, G; Duthaler, U; Huwyler, J; Keiser, J; Meister, I; Rinaldi, L1
Brennan, GP; Fairweather, I; Halferty, L; Keiser, J; O'Neill, JF1
Dong, Y; Keiser, J; Sriraghavan, K; Vargas, M; Vennerstrom, JL; Wang, X; Zhao, Q; Zhou, L1
Dong, Y; Haschke, M; Huwyler, J; Kaminsky, R; Keiser, J; Kirchhofer, C; Malikides, N; Vanhoff, K; Vennerstrom, JL1
Duthaler, U; Keiser, J; Smith, TA1
Huwyler, J; Keiser, J; Kirchhofer, C1
Braissant, O; Dong, Y; Keiser, J; Kirchhofer, C; Vargas, M; Vennerstrom, JL; Wang, X1
Dong, Y; Keiser, J; Tanner, M; Utzinger, J; Vennerstrom, JL1
Brennan, G; Dong, Y; Fairweather, I; Keiser, J; Utzinger, J; Vennerstrom, JL1

Trials

1 trial(s) available for adamantane and Fascioliasis

ArticleYear
Efficacy and pharmacokinetics of OZ78 and MT04 against a natural infection with Fasciola hepatica in sheep.
    Veterinary parasitology, 2013, Nov-15, Volume: 198, Issue:1-2

    Topics: Adamantane; Animals; Anthelmintics; Area Under Curve; Fasciola hepatica; Fascioliasis; Half-Life; Molecular Structure; Reproducibility of Results; Sheep; Sheep Diseases; Spiro Compounds

2013

Other Studies

8 other study(ies) available for adamantane and Fascioliasis

ArticleYear
Electron microscopical study to assess the in vitro effects of the synthetic trioxolane OZ78 against the liver fluke, Fasciola hepatica.
    Parasitology, 2009, Volume: 136, Issue:11

    Topics: Adamantane; Animals; Culture Media; Fasciola hepatica; Fascioliasis; Female; Male; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Rats; Rats, Wistar

2009
Structure-activity relationship of an ozonide carboxylic acid (OZ78) against Fasciola hepatica.
    Journal of medicinal chemistry, 2010, May-27, Volume: 53, Issue:10

    Topics: Adamantane; Animals; Anthelmintics; Fasciola hepatica; Fascioliasis; Female; Rats; Rats, Wistar; Stereoisomerism; Structure-Activity Relationship

2010
Efficacy, safety and pharmacokinetics of 1,2,4-trioxolane OZ78 against an experimental infection with Fasciola hepatica in sheep.
    Veterinary parasitology, 2010, Oct-29, Volume: 173, Issue:3-4

    Topics: Adamantane; Administration, Oral; Animals; Anthelmintics; Area Under Curve; Fasciola hepatica; Fascioliasis; Feces; Half-Life; Injections, Subcutaneous; Parasite Egg Count; Sheep; Sheep Diseases; Statistics, Nonparametric

2010
In vivo and in vitro sensitivity of Fasciola hepatica to triclabendazole combined with artesunate, artemether, or OZ78.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Adamantane; Animals; Anthelmintics; Artemisinins; Artesunate; Benzimidazoles; Fasciola hepatica; Fascioliasis; Female; Rats; Rats, Wistar; Triclabendazole

2010
Development and validation of a liquid chromatography/mass spectrometry method for pharmacokinetic studies of OZ78, a fasciocidal drug candidate.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Oct-15, Volume: 878, Issue:28

    Topics: Adamantane; Animals; Antiplatyhelmintic Agents; Chromatography, Liquid; Drug Stability; Fascioliasis; Mass Spectrometry; Reproducibility of Results; Sensitivity and Specificity; Sheep

2010
Activity of OZ78 analogues against Fasciola hepatica and Echinostoma caproni.
    Acta tropica, 2011, Volume: 118, Issue:1

    Topics: Adamantane; Animals; Anthelmintics; Echinostoma; Echinostomiasis; Fasciola hepatica; Fascioliasis; Female; Mice; Rats; Rats, Wistar; Treatment Outcome

2011
The synthetic peroxide OZ78 is effective against Echinostoma caproni and Fasciola hepatica.
    The Journal of antimicrobial chemotherapy, 2006, Volume: 58, Issue:6

    Topics: Adamantane; Animals; Antiplatyhelmintic Agents; Bile Ducts; Disease Models, Animal; Echinostoma; Echinostomiasis; Fasciola hepatica; Fascioliasis; Female; Mice; Microscopy, Electron, Scanning; Rats; Rats, Wistar

2006
Activity of artemether and OZ78 against triclabendazole-resistant Fasciola hepatica.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007, Volume: 101, Issue:12

    Topics: Adamantane; Administration, Oral; Animals; Antiplatyhelmintic Agents; Artemether; Artemisinins; Benzimidazoles; Bile Ducts; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Resistance; Fasciola hepatica; Fascioliasis; Female; Male; Rats; Rats, Sprague-Dawley; Rats, Wistar; Triclabendazole

2007