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adamantane and Cancer of Prostate

adamantane has been researched along with Cancer of Prostate in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's2 (16.67)18.2507
2000's3 (25.00)29.6817
2010's6 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdel-Samad, R; Abou-Kheir, W; Bahmad, HF; Cheaito, K; Darwiche, N; Hadadeh, O; Hayar, B; Liu, YN; Monzer, A; Msheik, H; Pisano, C; Samman, H1
Antoon, JW; Beckman, BS; Burow, ME; Gestaut, MM1
Keller, SN; Knudsen, KE; Schiewer, MJ; Schrecengost, RS; Smith, CD1
Darcy, R; Evans, JC; Fitzgerald, KA; Gooding, M; Malhotra, M; O'Driscoll, CM; Sallas, F1
Cao, H; Jung, M; Konsoula, Z; Velena, A1
Dimas, K; Eleutheriades, A; Foscolos, GB; Georgakopoulou, S; Khan, H; Kourafalos, VN; Mantelas, A; Mirjolet, JF; Moutsos, VI; Papanastasiou, I; Pondiki, S; Prassa, M; Riganas, S; Serin, G; Theodoropoulou, M; Tsotinis, A; Vamvakides, A; Zaniou, A1
Dawson, MI; Farhana, L; Fontana, JA; Freeman, RS; Huang, Y; Reddy, KB; Rishi, AK; Zhang, Y1
Dawson, MI; Farhana, L; Fontana, JA1
Doroshow, JH; Mukhopadhyay, I; Roy, KK; Sausville, EA1
Mittelman, A1
Barrie, SE; Chan, F; Houghton, J; Jarman, M; McCague, R; Potter, GA; Rowlands, MG1
Barrie, SE; Chan, FC; Haynes, BP; Houghton, J; Jarman, M; Potter, GA; Rowlands, MG1

Other Studies

12 other study(ies) available for adamantane and Cancer of Prostate

ArticleYear
The synthetic retinoid ST1926 attenuates prostate cancer growth and potentially targets prostate cancer stem-like cells.
    Molecular carcinogenesis, 2019, Volume: 58, Issue:7

    Topics: Adamantane; Animals; Antineoplastic Agents; Apoptosis; Carcinogenesis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cinnamates; DNA Damage; Humans; Male; Mice; Neoplasm Invasiveness; Neoplastic Stem Cells; Prostate; Prostatic Neoplasms; Retinoids; Xenograft Model Antitumor Assays

2019
Inhibition of sphingosine kinase-2 ablates androgen resistant prostate cancer proliferation and survival.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:1

    Topics: Adamantane; Androgen Antagonists; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Humans; Ki-67 Antigen; Male; Phosphotransferases (Alcohol Group Acceptor); Prostatic Neoplasms; Pyridines

2014
Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression.
    Molecular cancer research : MCR, 2015, Volume: 13, Issue:12

    Topics: Adamantane; Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Prostatic Neoplasms; Proto-Oncogene Proteins c-myc; Pyridines; Receptors, Androgen; Signal Transduction; Small-Conductance Calcium-Activated Potassium Channels; Xenograft Model Antitumor Assays

2015
A novel, anisamide-targeted cyclodextrin nanoformulation for siRNA delivery to prostate cancer cells expressing the sigma-1 receptor.
    International journal of pharmaceutics, 2016, Feb-29, Volume: 499, Issue:1-2

    Topics: Adamantane; beta-Cyclodextrins; Cations; Cell Cycle Proteins; Cell Line, Tumor; Gene Knockdown Techniques; Gene Transfer Techniques; Humans; Male; Nanoparticles; Particle Size; Polo-Like Kinase 1; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Receptors, sigma; RNA Interference; RNA, Small Interfering; Sigma-1 Receptor

2016
Adamantanyl-histone deacetylase inhibitor H6CAHA exhibits favorable pharmacokinetics and augments prostate cancer radiation sensitivity.
    International journal of radiation oncology, biology, physics, 2011, Apr-01, Volume: 79, Issue:5

    Topics: Adamantane; Animals; Area Under Curve; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Survival; DNA Damage; DNA Repair; DNA-Binding Proteins; Gamma Rays; Genes, BRCA1; Genes, BRCA2; Half-Life; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Male; Mice; Mice, Nude; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Rad51 Recombinase; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Stem Cell Assay; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2011
New adamantane phenylalkylamines with σ-receptor binding affinity and anticancer activity, associated with putative antagonism of neuropathic pain.
    Journal of medicinal chemistry, 2012, Nov-26, Volume: 55, Issue:22

    Topics: Adamantane; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Proliferation; Female; Humans; Male; Mice; Mice, SCID; Molecular Structure; Neuralgia; Ovarian Neoplasms; Pancreatic Neoplasms; Piperidines; Prostatic Neoplasms; Protein Binding; Receptors, sigma; Structure-Activity Relationship; Tumor Cells, Cultured

2012
Apoptosis signaling by the novel compound 3-Cl-AHPC involves increased EGFR proteolysis and accompanying decreased phosphatidylinositol 3-kinase and AKT kinase activities.
    Oncogene, 2004, Mar-11, Volume: 23, Issue:10

    Topics: Adamantane; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cinnamates; ErbB Receptors; Female; Humans; Male; Phosphatidylinositol 3-Kinases; Phosphorylation; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Transfection

2004
Apoptosis induction by a novel retinoid-related molecule requires nuclear factor-kappaB activation.
    Cancer research, 2005, Jun-01, Volume: 65, Issue:11

    Topics: 3T3 Cells; Adamantane; Animals; Apoptosis; bcl-X Protein; Breast Neoplasms; Cell Line, Tumor; Cinnamates; fas Receptor; Humans; I-kappa B Proteins; Male; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Prostatic Neoplasms; Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; RNA, Messenger; Transcription Factor RelA; X-Linked Inhibitor of Apoptosis Protein

2005
Molecular mechanism of adaphostin-mediated G1 arrest in prostate cancer (PC-3) cells: signaling events mediated by hepatocyte growth factor receptor, c-Met, and p38 MAPK pathways.
    The Journal of biological chemistry, 2006, Dec-08, Volume: 281, Issue:49

    Topics: Adamantane; Base Sequence; Cell Line, Tumor; Cell Proliferation; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; G1 Phase; Humans; Hydroquinones; Male; MAP Kinase Signaling System; Models, Biological; Nuclear Proteins; Nucleoplasmins; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-met; RNA, Small Interfering; Signal Transduction

2006
New agents for prostatic carcinoma.
    Urology, 1981, Volume: 17, Issue:4 Suppl

    Topics: Adamantane; Alkylating Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cisplatin; Estramustine; Fluorouracil; Humans; Male; Prostatic Neoplasms

1981
Esters of 3-pyridylacetic acid that combine potent inhibition of 17 alpha-hydroxylase/C17,20-lyase (cytochrome P45017 alpha) with resistance to esterase hydrolysis.
    Journal of medicinal chemistry, 1995, Oct-13, Volume: 38, Issue:21

    Topics: Adamantane; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds; Drug Resistance; Enzyme Inhibitors; Esterases; Esters; Female; Humans; Hydrolysis; Male; Microsomes, Liver; Placenta; Propionates; Prostatic Neoplasms; Rats; Steroid 17-alpha-Hydroxylase; Testis

1995
3- and 4-pyridylalkyl adamantanecarboxylates: inhibitors of human cytochrome P450(17 alpha) (17 alpha-hydroxylase/C17,20-lyase). Potential nonsteroidal agents for the treatment of prostatic cancer.
    Journal of medicinal chemistry, 1996, Aug-16, Volume: 39, Issue:17

    Topics: Adamantane; Animals; Antineoplastic Agents; Enzyme Inhibitors; Esterases; Humans; Kinetics; Male; Microsomes, Liver; Molecular Structure; Prostatic Neoplasms; Rats; Steroid 17-alpha-Hydroxylase; Structure-Activity Relationship

1996