Page last updated: 2024-08-21

adamantane and Benign Neoplasms

adamantane has been researched along with Benign Neoplasms in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.23)18.7374
1990's0 (0.00)18.2507
2000's6 (19.35)29.6817
2010's15 (48.39)24.3611
2020's9 (29.03)2.80

Authors

AuthorsStudies
Chen, X; Huang, H; Mu, X; Wang, D; Wei, S; Zhou, L1
Bae, KB; Kim, HH; Kim, K; Kim, S; Ko, YH; Lee, A; Li, M; Lim, HG; Park, KM; Shrinidhi, A1
Ahmed, M; Bissessur, R; Kabir, A; Nazeer, N1
Bao, X; Chen, Y; Hai, W; Lu, S; Peng, J; Shi, S; Xu, Y; Yu, Q; Zhang, M1
Pham, VH; Phan, DC; Phan, TPD; Vu, BD1
Dicembrini, I; Mannucci, E; Monami, M; Montereggi, C; Nreu, B1
Liu, Y; Liu, YH; Yu, Q; Zhang, B; Zhang, YM1
Xu, Y; Yang, W; Zhang, B1
Ban, HS; Chang, KY; Choi, Y; Kim, BK; Kim, I; Kim, M; Lee, K; Naik, R; Park, JH; Park, MK; Won, M1
Haris, U; Kagalwala, HN; Kim, YL; Lippert, AR1
Anderton, K; Bentz, TA; Brisendine, A; Britten, CD; Chin, SH; Cusack, SL; Garrett-Mayer, E; Maines, LW; Ogretmen, B; Shirai, K; Smith, CD; Thomas, MB; Zhuang, Y1
Chen, GR; He, XP; James, TD; Li, J; Liu, Y; Ma, X; Wang, H; Wang, X; Xu, C; Zang, Y1
Chen, Y; Fu, HG; Liu, Y; Yu, Q1
Iqbal, K; Schreiner, PR; Wanka, L1
Glushchenko, VA; Karitsky, AP; Kvashnin, AV; Rozengard, SA; Ryazankina, AA1
Han, S; Lee, K; Naik, R1
Alvarsson, M; Bhatt, DL; Cahn, A; Hirshberg, B; Hoekstra, JB; Im, K; Leiter, LA; Mosenzon, O; Raz, I; Scirica, BM; Stahre, CA; Teoh, H1
Li, J; Song, X; Wen, Y; Zhang, ZX; Zhao, F; Zhu, JL1
Cyphert, EL; Fu, AS; von Recum, HA1
De Meester, I; Lambeir, AM; Scharpé, S1
Bhuiyan, M; Chao, WR; Dawson, MI; Farhana, L; Feng, GS; Fontana, JA; Han, YH; Hobbs, PD; Jiang, T; Jong, L; Macchiarulo, A; Nuti, R; Pang, Y; Patel, B; Pellicciari, R; Su, Y; Tautz, L; Waleh, N; Xia, Z; Xue, LP; Ye, M; Zhang, XK1
Bergamini, P; Canella, A; Hajji, L; Romerosa, A; Saraiba-Bello, C; Segovia-Torrente, G; Serrano-Ruiz, M1
Buljubašić, M; Ilić, N; Kragol, G; Kralj, M; Marjanović, M; Mlinarić-Majerski, K; Ramljak, TŠ; Smuc, T; Supek, F; Zahradka, D1
Fan, H; Hu, QD; Liang, WQ; Tang, GP; Xu, FJ; Yang, WT1
Basarić, N; Cindro, N; Franković, O; Horvat, M; Kralj, M; Marjanović, M; Mlinarić-Majerski, K; Uzelac, L1
Dimas, K; Eleutheriades, A; Foscolos, GB; Georgakopoulou, S; Khan, H; Kourafalos, VN; Mantelas, A; Margarita, P; Moutsos, VI; Papanastasiou, I; Pondiki, S; Riganas, S; Theodoropoulou, M; Tsotinis, A; Vamvakides, A; Zaniou, A1
Bakker, A; Bellocq, NC; Brewster, M; Cheng, J; Davis, ME; Floren, W; Grubbs, BH; Janicot, M; Janssens, B; Jensen, GS; Pun, SH; Tack, F1
Carminati, P; Merlini, L; Penco, S; Pisano, C; Zunino, F1
Brabec, V; Intini, F; Kaspárková, J; Natile, G; Nováková, O; Vrána, O1
Ackerley, C; Clarke, DM; De Rosa, MF; Ito, S; Lingwood, C; Wang, B1
Creaven, PJ; Greco, WR; Karakousis, C; Madajewicz, S; Mittelman, A; Pontes, JE; Proefrock, A; Takita, H; Zakrzewski, SF1

Reviews

6 review(s) available for adamantane and Benign Neoplasms

ArticleYear
Risk of cancer in patients treated with dipeptidyl peptidase-4 inhibitors: an extensive meta-analysis of randomized controlled trials.
    Acta diabetologica, 2020, Volume: 57, Issue:6

    Topics: Adamantane; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Humans; Incidence; Neoplasms; Piperidines; Randomized Controlled Trials as Topic; Risk Factors; Sitagliptin Phosphate; Uracil; Vildagliptin

2020
ROS-responsive probes for low-background optical imaging: a review.
    Biomedical materials (Bristol, England), 2021, 02-03, Volume: 16, Issue:2

    Topics: Acoustics; Adamantane; Animals; Disease Progression; Fluorescent Dyes; Humans; Luminescence; Luminol; Mice; Neoplasms; Optical Imaging; Photochemistry; Photosensitizing Agents; Reactive Oxygen Species; Ultrasonic Therapy; Ultrasonics

2021
The lipophilic bullet hits the targets: medicinal chemistry of adamantane derivatives.
    Chemical reviews, 2013, May-08, Volume: 113, Issue:5

    Topics: Adamantane; Animals; Antineoplastic Agents; Antiparasitic Agents; Antiviral Agents; Central Nervous System Agents; Central Nervous System Diseases; Drug Discovery; Humans; Models, Molecular; Neoplasms; Virus Diseases; Viruses

2013
Chemical biology approach for the development of hypoxia inducible factor (HIF) inhibitor LW6 as a potential anticancer agent.
    Archives of pharmacal research, 2015, Volume: 38, Issue:9

    Topics: Acetanilides; Adamantane; Animals; Antineoplastic Agents; Clinical Trials as Topic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasms; Protein Structure, Secondary

2015
DPP4 inhibitors for diabetes--what next?
    Biochemical pharmacology, 2008, Dec-15, Volume: 76, Issue:12

    Topics: Adamantane; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Hypoxia; Neoplasms; Nitriles; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Triazoles; Vildagliptin

2008
Cellular and pharmacological bases of the antitumor activity of a novel adamantyl retinoid, ST1926.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16 Suppl 4

    Topics: Adamantane; Animals; Antineoplastic Agents; Apoptosis; Cinnamates; Disease Models, Animal; Humans; Leukemia, Myeloid, Acute; Mice; Neoplasms; Sensitivity and Specificity; Treatment Outcome; Tumor Cells, Cultured

2004

Trials

4 trial(s) available for adamantane and Benign Neoplasms

ArticleYear
A Phase I Study of ABC294640, a First-in-Class Sphingosine Kinase-2 Inhibitor, in Patients with Advanced Solid Tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2017, Aug-15, Volume: 23, Issue:16

    Topics: Adamantane; Adult; Aged; Dose-Response Relationship, Drug; Fatigue; Female; Humans; Male; Middle Aged; Nausea; Neoplasms; Phosphotransferases (Alcohol Group Acceptor); Pyridines; Treatment Outcome; Vomiting; Young Adult

2017
[Optimization of pharmacological therapy for weakness syndrome in incurable patients].
    Voprosy onkologii, 2015, Volume: 61, Issue:2

    Topics: Acetamides; Adamantane; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Antineoplastic Agents; Dexamethasone; Dopamine; Drug Therapy, Combination; Fatigue; Female; Humans; Hypnotics and Sedatives; Ibuprofen; Male; Middle Aged; Muscle Weakness; Neoplasms; Ondansetron; Pentoxifylline; Radiation-Protective Agents; Serotonin; Serotonin Antagonists; Syndrome; Treatment Outcome

2015
Frequency of cancer events with saxagliptin in the SAVOR-TIMI 53 trial.
    Diabetes, obesity & metabolism, 2016, Volume: 18, Issue:2

    Topics: Adamantane; Aged; Cohort Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Dyslipidemias; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Kidney; Male; Middle Aged; Mortality; Neoplasms; Risk Factors; Sex Factors; Smoking

2016
Phase I clinical trial and human pharmacokinetics of 2,4-diamino-5-adamantyl-6-methyl pyrimidine ethane sulfonate (DAMP-ES): a lipid-soluble antifolate.
    Cancer chemotherapy and pharmacology, 1988, Volume: 21, Issue:2

    Topics: Adamantane; Aged; Alkanesulfonates; Chemical Phenomena; Chemistry; Drug Evaluation; Female; Folic Acid Antagonists; Humans; Infusions, Intravenous; Male; Mathematics; Microcomputers; Middle Aged; Neoplasms; Software

1988

Other Studies

21 other study(ies) available for adamantane and Benign Neoplasms

ArticleYear
Polycyclodextrin as a linker for nanomedicine fabrication and synergistic anticancer application.
    Carbohydrate polymers, 2021, Dec-01, Volume: 273

    Topics: Adamantane; Animals; Antineoplastic Agents; Cyclodextrins; Female; Ferrocyanides; HeLa Cells; Humans; Isoindoles; Light; Mice, Inbred BALB C; Nanomedicine; Nanoparticles; Neoplasms; Organometallic Compounds; Photosensitizing Agents; Polymers; Reactive Oxygen Species; Ytterbium; Zinc Compounds

2021
Bio-orthogonal Supramolecular Latching inside Live Animals and Its Application for in Vivo Cancer Imaging.
    ACS applied materials & interfaces, 2019, Nov-27, Volume: 11, Issue:47

    Topics: Adamantane; Amphetamines; Animals; Caenorhabditis elegans; Cell Line, Tumor; Diagnostic Imaging; Female; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Mice; Mice, Inbred BALB C; Neoplasms

2019
Diatoms embedded, self-assembled carriers for dual delivery of chemotherapeutics in cancer cell lines.
    International journal of pharmaceutics, 2020, Jan-05, Volume: 573

    Topics: Adamantane; Antineoplastic Combined Chemotherapy Protocols; Cyclodextrins; Diatomaceous Earth; Doxorubicin; Drug Antagonism; Drug Carriers; Drug Compounding; Drug Synergism; HeLa Cells; Humans; Nanoparticles; Neoplasm Recurrence, Local; Neoplasms; Paclitaxel

2020
Multi-functional self-assembled nanoparticles for pVEGF-shRNA loading and anti-tumor targeted therapy.
    International journal of pharmaceutics, 2020, Feb-15, Volume: 575

    Topics: A549 Cells; Adamantane; Animals; DNA; Female; Gene Silencing; Humans; Mice, Nude; Molecular Targeted Therapy; Nanoparticles; Neoplasms; Neovascularization, Pathologic; Peptides; Plasmids; Polymers; RNA, Small Interfering; Tumor Burden; Vascular Endothelial Growth Factor A

2020
Synthesis and Bioactivity of Thiosemicarbazones Containing Adamantane Skeletons.
    Molecules (Basel, Switzerland), 2020, Jan-13, Volume: 25, Issue:2

    Topics: A549 Cells; Adamantane; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Bacteria; Candida albicans; HeLa Cells; Humans; MCF-7 Cells; Neoplasms; Thiosemicarbazones

2020
Actin Cytoskeleton-Disrupting and Magnetic Field-Responsive Multivalent Supramolecular Assemblies for Efficient Cancer Therapy.
    ACS applied materials & interfaces, 2020, Mar-25, Volume: 12, Issue:12

    Topics: Actin Cytoskeleton; Adamantane; Humans; Hyaluronic Acid; Magnetic Field Therapy; Magnetic Fields; Nanofibers; Nanoparticles; Neoplasms; Peptides; Polylysine

2020
The disubstituted adamantyl derivative LW1564 inhibits the growth of cancer cells by targeting mitochondrial respiration and reducing hypoxia-inducible factor (HIF)-1α accumulation.
    Experimental & molecular medicine, 2020, Volume: 52, Issue:11

    Topics: Adamantane; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Respiration; Dose-Response Relationship, Drug; Electron Transport Chain Complex Proteins; Energy Metabolism; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lipid Metabolism; Mice; Mitochondria; Neoplasms; Oxygen Consumption; Signal Transduction

2020
Seeking Illumination: The Path to Chemiluminescent 1,2-Dioxetanes for Quantitative Measurements and
    Accounts of chemical research, 2021, 07-06, Volume: 54, Issue:13

    Topics: Adamantane; Animals; beta-Galactosidase; Heterocyclic Compounds, 1-Ring; Humans; Hydrogen-Ion Concentration; Hypoxia; Luminescence; Luminescent Agents; Neoplasms; Optical Imaging; Spiro Compounds

2021
Supramolecular glyco-poly-cyclodextrin functionalized thin-layer manganese dioxide for targeted stimulus-responsive bioimaging.
    Chemical communications (Cambridge, England), 2018, Apr-17, Volume: 54, Issue:32

    Topics: Acrylamides; Adamantane; Asialoglycoprotein Receptor; beta-Cyclodextrins; Cell Line, Tumor; Drug Stability; Fluorescent Dyes; Humans; Lectins, C-Type; Ligands; Macromolecular Substances; Manganese Compounds; Mannose Receptor; Mannose-Binding Lectins; Naphthalimides; Neoplasms; Oxides; Receptors, Cell Surface

2018
A tumor-targeting Ru/polysaccharide/protein supramolecular assembly with high photodynamic therapy ability.
    Chemical communications (Cambridge, England), 2019, Mar-07, Volume: 55, Issue:21

    Topics: A549 Cells; Adamantane; beta-Cyclodextrins; Cell Line; Coordination Complexes; Drug Delivery Systems; Humans; Models, Molecular; Neoplasms; Photochemotherapy; Photosensitizing Agents; Ruthenium; Transferrin

2019
Thermoresponsive supramolecular micellar drug delivery system based on star-linear pseudo-block polymer consisting of β-cyclodextrin-poly(N-isopropylacrylamide) and adamantyl-poly(ethylene glycol).
    Journal of colloid and interface science, 2017, Mar-15, Volume: 490

    Topics: Acrylic Resins; Adamantane; Antibiotics, Antineoplastic; beta-Cyclodextrins; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Doxorubicin; Humans; Micelles; Neoplasms; Polyethylene Glycols; Temperature

2017
Featured Article: Chemotherapeutic delivery using pH-responsive, affinity-based release.
    Experimental biology and medicine (Maywood, N.J.), 2017, Volume: 242, Issue:7

    Topics: Adamantane; Antibiotics, Antineoplastic; Cell Line, Tumor; Dextrans; Doxorubicin; Drug Delivery Systems; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Neoplasms; Polymers; Spectroscopy, Fourier Transform Infrared

2017
Adamantyl-substituted retinoid-derived molecules that interact with the orphan nuclear receptor small heterodimer partner: effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis, and
    Journal of medicinal chemistry, 2008, Sep-25, Volume: 51, Issue:18

    Topics: Adamantane; Antineoplastic Agents; Apoptosis; Cell Division; Cell Line, Tumor; Cinnamates; Dimerization; Enzyme Inhibitors; Humans; Models, Molecular; Neoplasms; Protein Tyrosine Phosphatase, Non-Receptor Type 11

2008
Water-soluble Cp ruthenium complex containing 1,3,5-triaza-7-phosphaadamantane and 8-thiotheophylline derivatives: synthesis, characterization, and antiproliferative activity.
    Inorganic chemistry, 2011, Feb-07, Volume: 50, Issue:3

    Topics: Adamantane; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cisplatin; Crystallography, X-Ray; Humans; Models, Molecular; Neoplasms; Organophosphorus Compounds; Ruthenium Compounds; Solubility; Theophylline; Water

2011
Could LogP be a principal determinant of biological activity in 18-crown-6 ethers? Synthesis of biologically active adamantane-substituted diaza-crowns.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:8

    Topics: Adamantane; Algorithms; Antineoplastic Agents; Bacillus subtilis; Cell Cycle; Cell Line, Tumor; Cell Survival; Crown Ethers; Drug Design; Drug Screening Assays, Antitumor; Escherichia coli; Ethers; Female; Humans; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Models, Molecular; Neoplasms; Quantitative Structure-Activity Relationship; Software; Species Specificity; Structure-Activity Relationship

2011
In vivo treatment of tumors using host-guest conjugated nanoparticles functionalized with doxorubicin and therapeutic gene pTRAIL.
    Biomaterials, 2012, Volume: 33, Issue:5

    Topics: Adamantane; Animals; beta-Cyclodextrins; Cell Death; Cell Line, Tumor; Doxorubicin; Female; Flow Cytometry; Green Fluorescent Proteins; Humans; Mice; Mice, Nude; Microscopy, Confocal; Nanoparticles; Neoplasms; Plasmids; Polyethyleneimine; TNF-Related Apoptosis-Inducing Ligand

2012
Evaluation of antiproliferative effect of N-(alkyladamantyl)phthalimides in vitro.
    Chemical biology & drug design, 2012, Volume: 79, Issue:4

    Topics: Adamantane; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Humans; Neoplasms; Phthalimides; Structure-Activity Relationship

2012
New adamantane derivatives with sigma affinity and antiproliferative activity.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2012, Volume: 8, Issue:4

    Topics: Adamantane; Animals; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Drug Design; Female; Humans; Male; Mice; Mice, SCID; Neoplasms; Receptors, sigma

2012
Targeted delivery of RNA-cleaving DNA enzyme (DNAzyme) to tumor tissue by transferrin-modified, cyclodextrin-based particles.
    Cancer biology & therapy, 2004, Volume: 3, Issue:7

    Topics: Adamantane; Animals; Cyclodextrins; DNA, Catalytic; Drug Carriers; Drug Delivery Systems; Gene Transfer Techniques; Infusions, Intravenous; Infusions, Parenteral; Male; Mice; Neoplasms; Plasmids; Polyethylene Glycols; Transferrin

2004
Molecular aspects of antitumor effects of a new platinum(IV) drug.
    Molecular pharmacology, 2006, Volume: 70, Issue:5

    Topics: Adamantane; Animals; Antineoplastic Agents; Ascorbic Acid; Base Sequence; Cell Line, Tumor; Cell-Free System; Cross-Linking Reagents; DNA; DNA Adducts; DNA Repair; DNA-Directed RNA Polymerases; HeLa Cells; High Mobility Group Proteins; HIV-1; Humans; Molecular Sequence Data; Neoplasms; Organoplatinum Compounds; Plasmids; Platinum; Rats; RNA-Directed DNA Polymerase; Sulfur Compounds; Viral Proteins

2006
Inhibition of multidrug resistance by adamantylgb3, a globotriaosylceramide analog.
    The Journal of biological chemistry, 2008, Feb-22, Volume: 283, Issue:8

    Topics: Adamantane; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Calcium Channel Blockers; Cell Membrane; Cell Polarity; Cyclosporine; Dogs; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Endocytosis; Enzyme Inhibitors; Fluorescent Dyes; Golgi Apparatus; Humans; Intestinal Mucosa; Neoplasms; Protein Binding; Protein Structure, Secondary; Protein Synthesis Inhibitors; Protein Transport; Rhodamine 123; Shiga Toxins; Time Factors; Trihexosylceramides; Up-Regulation; Verapamil; Vinblastine

2008