acyclovir and Mumps

Lipschütz ulcers are characterised by a first flare of non-sexually related acute genital ulcers (AGU) occurring in adolescent girls. Epstein-Barr primary infection is the most frequently reported aetiology but other infectious agents are probably implicated. We report the first case of mumps associated with an AGU in a 21-year-old girl. She presented a bilateral parotitis with genital ulcers, and serology confirmed she had mumps. As in our case, most Lipschütz ulcers heal spontaneously within a couple of weeks and the diagnosis should be reconsidered in case of recurrence.

Topics: Acute Disease; Acyclovir; Antiviral Agents; Female; Humans; Immunoglobulin G; Immunoglobulin M; Mumps; Mumps virus; Skin Ulcer; Treatment Outcome; Valacyclovir; Valine; Vulvar Diseases; Young Adult

Childhood infectious diseases are not usually serious. The symptoms (fever, conjunctivitis, itching) diminish with the administration of antipyretic drugs. Cutaneous lesions leave no scarring. Sometimes complications may appear.

Topics: Acyclovir; Administration, Cutaneous; Antiviral Agents; Chickenpox; Child; Chorioretinitis; Conjunctivitis, Viral; Drug Therapy, Combination; Eye Infections, Viral; Glucocorticoids; Humans; Measles; Mumps; Pruritus; Rubella; Skin Diseases, Viral; Treatment Outcome

Acute viral and other infectious causes of encephalitis usually produce fever, headache, stiff neck and alterations in consciousness, focal neurologic signs and seizures. A large number of viral and nonviral agents can cause encephalitis. Arthropod-borne viruses peak in summer, the tick-borne infections occur in early summer, enterovirus infections in later summer and mumps in the winter and spring.

Topics: Acyclovir; Encephalitis; Encephalitis, Tick-Borne; Enterovirus Infections; Herpes Simplex; Humans; Mumps; Seasons

Topics: Acyclovir; Administration, Ophthalmic; Antibodies, Viral; Antiviral Agents; Atrophy; Child; Enzyme-Linked Immunosorbent Assay; Eye Infections, Viral; Female; Glucocorticoids; Humans; Immunoglobulin G; Infusions, Intravenous; Intraocular Pressure; Mumps; Mumps virus; Prednisolone; Retinal Necrosis Syndrome, Acute; Retinal Pigment Epithelium; Tomography, Optical Coherence; Visual Acuity

Topics: Acyclovir; Anti-Bacterial Agents; Bacterial Infections; Chancroid; Chlamydia Infections; Epididymitis; Escherichia coli Infections; Female; Genital Diseases, Male; Herpes Simplex; Humans; Infertility, Male; Male; Mumps; Orchitis; Prostatitis; Syphilis; Urethritis

A 16-year-old male diabetic patient presented with bilateral salivary gland swellings followed by encephalitis. The EEG did not show the characteristic periodic lateralising epileptic discharges. Neuro-imaging disclosed compromise of temporal and frontal lobes as well as brain stem which correlated well with his clinical deterioration. Serology and frontal brain biopsy were positive for herpes simplex virus while mumps titers were not significant. Despite delayed acyclovir therapy, the patient recovered enough to be discharged home with a permanent pseudobulbar palsy. Herpes simplex encephalitis involving zones other than temporal lobes is exceptional. To our knowledge, there are no reported cases of pseudobulbar palsy as a sequelae of HSV encephalitis.

Topics: Acyclovir; Adolescent; Biopsy; Brain; Brain Damage, Chronic; Diagnosis, Differential; Encephalitis; Follow-Up Studies; Herpes Simplex; Humans; Inclusion Bodies, Viral; Magnetic Resonance Imaging; Male; Microscopy, Electron; Mumps; Neurologic Examination