acyclovir and Mastitis

Herpetic lesions most frequently occur on oral and genital areas. However, herpes simplex virus (HSV) can be a rare cause of breast infection. In few published articles, the route of transmission is predominantly from infant to mother. We report two cases about simultaneous mammary and extramammary (oral and genital) herpetic infection in nonlactating women. In both cases, HSV breast lesions were acquired by sexual contacts with partners who were asymptomatic HSV carriers. Through a review of literature, we highlight clinical signs for an early diagnosis. We also emphasize the advantage of the valacyclovir for treating this uncommon pathology.

Topics: Acyclovir; Adult; Antiviral Agents; Female; Herpes Simplex; Humans; Mastitis; Valacyclovir; Valine

A young woman presented with worsening bilateral periareolar mastitis associated with skin necrosis and delayed vesical formation after oral nipple manipulation by her sexual partner. After multiple failed antibiotic regimens, she was diagnosed with herpes simplex virus 1 (HSV-1) infection. This case demonstrates an uncommon etiology of breast mastitis. We highlight the importance of a timely diagnosis and early administration of antiviral therapy.

Topics: Acyclovir; Adult; Antiviral Agents; Breast Neoplasms; Female; Herpes Simplex; Herpesvirus 1, Human; Humans; Mastitis

Topics: Acyclovir; Adult; Antiviral Agents; Breast Feeding; Female; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Mastitis; Nipples; Valacyclovir; Valine