acyclovir and Lymphoma--T-Cell

acyclovir has been researched along with Lymphoma--T-Cell* in 5 studies

Reviews

1 review(s) available for acyclovir and Lymphoma--T-Cell

ArticleYear
Viral lesions of the mouth in HIV-infected patients.
    Dermatology (Basel, Switzerland), 1997, Volume: 194, Issue:1

    Viral lesions of the mouth in patients with HIV infection are common and these diseases any be a marker for HIV and disease progression. We review the spectrum of oral viral manifestations and discuss treatment modalities. The most common Epstein-Barr virus (EBV)-induced disorder in HIV-infected patients is oral hairy leukoplakia. EBV-related oral B-cell and T-cell lymphoma in AIDS patients has been described repeatedly. Herpes virus type 1 and rarely type 2 may lead to painful and resistant oral ulcers, and systemic treatment with acyclovir, valaciclovir or famciclovir is indicated. In acyclovir-resistant cases foscarnet is the treatment of choice. In recent years it has been documented that Kaposi's sarcoma, which often affects oral mucosa, is probably induced by herpesvirus type 8. Cytomegalovirus was found in 53% of cases with herpesviridae-induced mucosal ulcers as the only ulcerogenic viral agent in AIDS patients. In severe cytomegalovirus infection treatment with ganciclovir is helpful. Viral warts induced by different HPV may occur in the mouth. Several physical treatment modalities are possible in the oral mucosa. In AIDS patients mollusca contagiosa may occur as large and atypical lesions in the face and lips and rarely in the oral cavity. Cryotherapy is a bloodless treatment in such patients.

    Topics: 2-Aminopurine; Acyclovir; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cytomegalovirus Infections; Disease Progression; Famciclovir; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 4, Human; Herpesvirus 8, Human; Humans; Leukoplakia, Hairy; Lymphoma, B-Cell; Lymphoma, T-Cell; Molluscum Contagiosum; Mouth Diseases; Mouth Neoplasms; Oral Ulcer; Prodrugs; Sarcoma, Kaposi; Stomatitis, Herpetic; Tumor Virus Infections; Valacyclovir; Valine; Virus Diseases; Warts

1997

Other Studies

4 other study(ies) available for acyclovir and Lymphoma--T-Cell

ArticleYear
Generalized maculopapular and vesicular rash.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2018, Volume: 16, Issue:2

    Topics: Acyclovir; Aged; Bendamustine Hydrochloride; Drug Eruptions; Epidermis; Herpes Zoster; Humans; Immunoblastic Lymphadenopathy; Keratinocytes; Lymphocytes; Lymphoma, T-Cell; Male; Programmed Cell Death 1 Receptor; Skin

2018
Systemic varicella zoster virus reinfection in a case of angioimmunoblastic T-cell lymphoma.
    The Journal of dermatology, 2007, Volume: 34, Issue:6

    Angioimmunoblastic T-cell lymphoma (AITL) is a rare subtype of peripheral T-cell lymphoma that causes immunological disorders such as immunosuppression, autoimmune disease-like symptoms and allergy. We report a case of a 67-year-old man with AITL who had a serious varicella zoster virus (VZV) reinfection that appeared clinically to be varicella. Forty percent of cases of AITL are associated with skin rash. A variety of cutaneous manifestations have been reported; however, the majority are macropapular eruptions that are often diagnosed as drug associated. Our study emphasizes the need to correctly diagnose opportunistic infections, such as the varicella that is documented in our patient, at early stages in AITL.

    Topics: Acyclovir; Aged; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Chickenpox; Cyclophosphamide; Diagnosis, Differential; Doxorubicin; Herpesvirus 3, Human; Humans; Immunocompromised Host; Infusions, Intravenous; Lymphoma, T-Cell; Male; Prednisone; Recurrence; Vincristine

2007
Epstein-Barr virus load correlating with clinical manifestation and treatment response in a patient with angioimmunoblastic T-cell lymphoma.
    Antiviral therapy, 2004, Volume: 9, Issue:3

    Epstein-Barr virus (EBV)-associated lymphoma may arise secondary to angioimmunoblastic T-cell lymphoma (AITL). The prognosis is poor despite chemotherapy and experimental therapies. We report on a 40-year-old woman with AITL without obvious immunodeficiency in which EBV-associated lymphoma developed. The occurrence and size of enlarged lymph nodes correlated strongly with the EBV load in serum (EBVL). Treatment with valacyclovir at the early stage resulted in a drastic more than 3 log10 decrease of EBVL and complete remission. However, valacyclovir had to be stopped after 6 months due to side effects, and the lymphoma reoccurred 3 months later associated with increasing EBVL. Eventually started cytotoxic chemo- and anti-CD20 therapy resulted only in partial remission. The lymphoma progressed and 33 months after it was diagnosed the patient died. This case report demonstrates the close association of EBVL and AITL and a beneficial effect of antiviral therapy at an initial stage of disease manifestation.

    Topics: Acyclovir; Adult; Antiviral Agents; Fatal Outcome; Female; Herpesvirus 4, Human; Humans; Immunoblastic Lymphadenopathy; Immunocompetence; Lymph Nodes; Lymphoma, T-Cell; Radiography; RNA, Viral; Staining and Labeling; Valacyclovir; Valine; Viral Load; Viral Matrix Proteins

2004
[Acyclovir-resistance zona in a immunocompromised HIV seronegative patient].
    Annales de dermatologie et de venereologie, 1998, Volume: 125, Issue:2

    Resistance to antiviral therapy is getting actually more frequent. Immunocompromised host are more concerned with this problem.. We present a case of disseminated zoster resisting to acyclovir (ACV) therapy, but healing with foscarnet in a man treated with chemotherapy for lymphoma and seronegative for HIV. CI50 of VZV strain was 48 microM for ACV, which was 2.8 times higher than value of the reference OKA strain tested simultaneously, which confirmed the resistance for ACV.. Immunocompromised patients often present varicella zoster virus (VZV) infection. They usually heal in response to ACV therapy, but some HIV infected patients have already presented with resistant strains of VZV. This case is the first described in a non-HIV infected patient. Foscarnet therapy resulted twice in complete healing because of its direct activity on viral DNA polymerase, so it is efficaceous therapy for patients with thymidine-kinase-deficient ACV-resistant VZV infection.

    Topics: Acyclovir; Antiviral Agents; Drug Resistance, Microbial; Foscarnet; Herpes Zoster; HIV Seronegativity; Humans; Immunocompromised Host; Lymphoma, T-Cell; Male; Middle Aged

1998