acyclovir and Intracranial-Hemorrhages

Topics: Acyclovir; Antiviral Agents; Erythema; Facial Dermatoses; Facial Pain; Herpes Zoster Ophthalmicus; Humans; Immunocompetence; Intracranial Hemorrhages; Male; Middle Aged; Radiography; Treatment Outcome

We describe a rare case of Influenza B-associated encephalopathy with hemorrhagic lesions of the corpus callosum. A 12-year-old Caucasian girl presented a 24-h fever followed by partial seizure, secondarily generalized, and disturbance of consciousness. Magnetic resonance imaging on Day 2 of her illness showed two hemorrhagic lesions of the corpus callosum. The Influenza B virus was found on nasopharyngeal swab. Neurologic signs had completely recovered by Day 3. A review of the literature identified a few similar cases; the common features include a relatively older age and prompt and complete recovery from clinical symptoms. This is the first report to describe hemorrhagic lesions of the corpus callosum in influenza.

Topics: Acyclovir; Anticonvulsants; Antiviral Agents; Child; Clonazepam; Corpus Callosum; Encephalitis, Viral; Female; Humans; Influenza B virus; Influenza, Human; Intracranial Hemorrhages; Magnetic Resonance Imaging; Neurologic Examination; Seizures, Febrile