acyclovir and Hand-Dermatoses

Lymphangitis and lymphedema are rarely reported complications of herpetic hand or genital infection. The natural history of these complications is gradual resolution over 14 to 21 days. Recognition of this presentation of herpes infection avoids unnecessary surgery and antibacterial therapy. Antiviral therapy may have a role in shortening the duration of symptoms and aborting recurrent lymphangitic episodes.

Topics: Acyclovir; Administration, Oral; Adult; Female; Fingers; Hand Dermatoses; Herpes Simplex; Humans; Lymphangitis; Male; Middle Aged; Recurrence

Topics: Acyclovir; Antiviral Agents; Diagnosis, Differential; Hand Dermatoses; Herpes Simplex; Humans; Male; Middle Aged; Recurrence; Simplexvirus

Topics: Acyclovir; Adult; Antiviral Agents; Diagnosis, Differential; Exanthema; Hand Dermatoses; Herpes Simplex; Humans; Male; Skin Diseases, Vesiculobullous; Spider Bites; Thumb; Valacyclovir; Valine

Topics: Acyclovir; Adult; Antiviral Agents; Blister; Diagnosis, Differential; Female; Hand Dermatoses; Herpes Simplex; Humans; Prodrugs; Real-Time Polymerase Chain Reaction; Recurrence; Valacyclovir; Valine

Topics: Acyclovir; Adult; Animals; Antiviral Agents; Blister; Diagnosis, Differential; Female; Hand Dermatoses; Hedgehogs; Herpes Zoster; Humans; Skin

Topics: Acyclovir; Antiviral Agents; Diabetes Mellitus, Type 1; Female; Hand Dermatoses; Herpes Simplex; Humans; Immunohistochemistry; Middle Aged; Pseudolymphoma; Valacyclovir; Valine

Topics: Acyclovir; Aged; Antiviral Agents; Biopsy; Dermis; Diagnosis, Differential; Female; Follow-Up Studies; Granuloma Annulare; Hand Dermatoses; Herpes Zoster; Humans; Injections, Intravenous; Remission, Spontaneous; Scalp Dermatoses; Thoracic Wall

Topics: Acyclovir; Adult; Diagnosis, Differential; Female; Follow-Up Studies; Hand Dermatoses; Herpes Simplex; Herpesvirus 2, Human; Humans; Recurrence; Severity of Illness Index; Skin Diseases, Vesiculobullous; Treatment Outcome

We present a case of herpetic gingivostomatitis and finger infection. Vesicular hand lesions may result from autoinoculation of oral herpes simplex virus (HSV) infection in children, which may be evident or asymptomatic.

Topics: Acyclovir; Antiviral Agents; Fingers; Hand Dermatoses; Herpes Simplex; Humans; Infant; Male; Stomatitis, Herpetic; Virus Shedding

Topics: Acyclovir; Adult; Antiviral Agents; Dermatitis, Atopic; Hand Dermatoses; Humans; Kaposi Varicelliform Eruption; Male; Penile Diseases; Recurrence

Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Antiviral Agents; Female; Fingers; Hand Dermatoses; Herpes Simplex; Humans

Herpes simplex virus infection in immunocompromised individuals, including AIDS patients, is characterized by its tendency for atypical presentations and unusual locations, often resulting in delayed diagnosis and treatment. Three HIV-infected patients who developed prolonged cutaneous lesions of the fingers are presented. These lesions were unmodified by previous antibiotic treatment, and rapidly progressed to the complete destruction of nail structures in two patients. Viral culture confirmed the diagnosis of herpetic whitlow in all cases, and treatment with oral acyclovir resulted in complete recovery. Surgical treatment was not necessary.

Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Female; Fingers; Hand Dermatoses; Herpes Simplex; Humans; Male

Herpes simplex virus (HSV) infection of the hand occurs predominantly in three different population groups. Young adults with a recurrent HSV II infection of the hand account for the majority of cases. A prodromal phase of up to 72 hours and a recurrence of seven to 10 days' duration occasionally associated with lymphangitis, lymphadenopathy, and lymphedema are characteristic. HSV I infection of the hand classically occurs in children with herpetic stomatitis and in health care workers infected during patient care delivery. In health care workers, the infection may last 21 to 28 days and be associated with severe pain and lymphangitis. Recurrences appear uncommon in HSV I infections. Primary infection is usually managed conservatively. Vesicle drainage for pain relief and antiviral therapy with acyclovir may be of value. For recurrent infections, acyclovir, 800 mg orally, twice daily, initiated during the prodrome in an open study of eight patients appeared effective in aborting the attack. Evaluation of long-term suppression in recurrent HSV infection of the hand is in progress.

Topics: Acyclovir; Adult; Female; Hand Dermatoses; Herpes Simplex; Humans; Idoxuridine; Infant; Recurrence

The herpes simplex virus can cause both oral and cutaneous lesions. Herpetic whitlow is a cutaneous manifestation of a herpetic infection. The source of the infection for many medical and dental professionals is the oral cavity. Acyclovir, an antiviral agent used in the treatment of herpes simplex virus infections, was administered in the treatment of herpetic whitlow. Controlled studies of acyclovir therapy for herpetic whitlow have not been done; however, its use by health care providers to treat the symptoms of herpetic whitlow and a review of the disease are discussed in this case report.

Topics: Acyclovir; Adult; Dentists; Dermatitis, Occupational; Fingers; Hand Dermatoses; Herpes Simplex; Humans; Male

Topics: Acyclovir; Adult; Female; Hand Dermatoses; Humans; Pemphigoid Gestationis; Pregnancy; Pregnancy Complications; Skin Diseases, Vesiculobullous

Topics: Acyclovir; Administration, Oral; Adult; Female; Hand Dermatoses; Herpes Simplex; Humans; Physicians; Recurrence; Thumb; Time Factors

Topics: Acyclovir; Adolescent; Female; Fingers; Hand Dermatoses; Herpes Simplex; Humans