acyclovir and Granuloma-Inguinale

Although atypical presentations of herpetic infection in immunocompetent individuals are common, they very rarely have the extensive, chronic and verrucous appearances seen in the immunocompromised host. We report a case of genital herpes manifesting as painless chronic non-healing genital ulcers with exuberant granulation tissue in an immunocompetent man. Owing to this morphology, the ulcers were initially mistaken for donovanosis. To the best of our knowledge, such a presentation of genital herpes in an immunocompetent individual has not been described previously.

Topics: Acyclovir; Antiviral Agents; Calymmatobacterium; Diagnosis, Differential; Granuloma Inguinale; Herpes Genitalis; Herpesvirus 1, Human; Herpesvirus 2, Human; HIV-1; Humans; Immunocompetence; Male; Polymerase Chain Reaction; Simplexvirus; Treatment Outcome; Ulcer