acyclovir and Brain-Abscess

Topics: Acyclovir; Adult; Anti-Bacterial Agents; Antiviral Agents; Brain Abscess; Cefotaxime; Diagnosis, Differential; Humans; Magnetic Resonance Imaging; Male; Meningitis; Tomography, X-Ray Computed

We report a case of a large intracerebral CSF collection formed along the course of the catheter of an ommaya-type reservoir (Medtronic 12 mm), implanted in a patient suffered from cryptococcal meningitis in the frame of CLL. This collection was at first diagnosed as intracerebral abscess but emergency craniotomy proves clear CSF collection with no signs of infection. We describe the case and we discuss the issue of CSF pressure pathophysiology and changes in flow dynamics, to patients with cryptococcal meningitis.

Topics: Acyclovir; Aged; Amphotericin B; Anti-Infective Agents; Brain Abscess; Ceftriaxone; Cerebrospinal Fluid; Cerebrospinal Fluid Pressure; Diagnosis, Differential; Drainage; Fluconazole; Humans; Magnetic Resonance Imaging; Male; Meningitis, Cryptococcal; Metronidazole; Spinal Puncture; Teicoplanin

Actinomycosis is a subacute or chronic bacterial infection, which can affect immunocompetent or immunodeficient subjects. It most often occurs in cervico-facial or thoracic-abdominal locations. Central nervous system infection is rare but of severe prognosis.. A 56 year-old woman with no history of immunodepression was admitted with unexplained fever, inappropriate behaviour, and spatial and temporal disorientation. The progressive worsening of the neurological signs let to coma and mechanical ventilation was required. Brain imaging showed multilocation cerebral abscesses. Stereotaxial biopsy permitted diagnosis of actinomycosis. Patient's outcome was favourable following appropriate dual antibiotherapy without surgical exeresis.. When lacking bacteriologic identification, diagnosis of cerebral actinomycosis is performed by pathologic findings. Dual antibiotherapy allows full recover, even in the case of multilocation cerebral abscesses.

Topics: Actinomyces; Actinomycosis; Acyclovir; Amoxicillin; Biopsy; Brain Abscess; Chloramphenicol; Clindamycin; Coma; Diagnostic Errors; Drug Therapy, Combination; Encephalitis, Herpes Simplex; Female; Fever; Humans; Listeriosis; Magnetic Resonance Imaging; Meningoencephalitis; Middle Aged; Nocardia Infections; Remission Induction; Tuberculosis, Meningeal

Topics: Acyclovir; Brain Abscess; Cefepime; Cephalosporins; Ethnicity; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Taiwan; Vancomycin