acyclovir and Astigmatism

A 40-year-old woman presented with an unusual form of corneal herpetic reactivation 5 weeks after laser in situ keratomileusis. The cornea showed diffuse edema and a stromal ring infiltrate (disciform in appearance). Oral antiviral and topical steroids in tapered dosages were administered. The infiltrate disappeared within 6 weeks. Progressive improvement was also seen in all the parameters on Pentacam scans, including the pachymetry, keratometry readings, and elevation on the anterior float. Herpetic reactivation may occur in many forms after excimer laser ablation. Timely diagnosis and management is crucial to maintain good structural and visual outcomes. Pentacam analysis may serve as a useful adjunct in following the progression of herpetic reactivation cases.

Topics: Acyclovir; Adult; Antiviral Agents; Astigmatism; Cornea; Corneal Topography; Drug Therapy, Combination; Female; Glucocorticoids; Herpesvirus 1, Human; Humans; Keratitis, Herpetic; Keratomileusis, Laser In Situ; Lasers, Excimer; Myopia; Prednisolone; Virus Activation; Visual Acuity

A woman with a history of recurrent herpes simplex keratitis in the left eye developed endothelial and stromal keratitis after cataract extraction. Because of the resultant corneal distortion a high regular astigmatism appeared. An arcuate keratotomy was performed to improve her visual acuity.. Corneal astigmatism can appear after herpetic keratitis. An arcuate keratotomy was effective in this case to decrease astigmatism and improve her vision. Keratitis reactivation is possible so antiviral prophylaxis is advisable. Our good results show that arcuate keratotomy can be a useful technique for these patients.

Topics: Acyclovir; Antiviral Agents; Astigmatism; Dexamethasone; Drug Therapy, Combination; Female; Humans; Keratitis, Herpetic; Lens Implantation, Intraocular; Middle Aged; Ophthalmologic Surgical Procedures; Phacoemulsification; Postoperative Complications; Tobramycin; Valacyclovir; Valine; Virus Activation

A 40-year-old woman underwent bilateral Laser In Situ Keratomileusis (LASIK) for the correction of myopia and astigmatism. The day after, four dendritic ulcers appeared in her left eye. She was treated with topical antiviral agents until complete recovery. She had a history of recurrent labial herpetic infection.. Reactivation of herpes simplex virus type 1 can occur, even without any previous history of corneal infection. Although this does not contraindicate surgery, all patients with a history of herpetic infection should be made aware of the complications related to this technique.

Topics: Acyclovir; Adrenal Cortex Hormones; Adult; Antiviral Agents; Astigmatism; Female; Herpes Labialis; Humans; Keratitis, Herpetic; Keratomileusis, Laser In Situ; Myopia; Postoperative Complications

Topics: Acute Disease; Acyclovir; Adult; Antiviral Agents; Astigmatism; Cornea; Eye Foreign Bodies; Eyelids; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Keratitis, Herpetic; Male; Visual Acuity