Page last updated: 2024-10-31

activins and Pulmonary Hypertension

activins has been researched along with Pulmonary Hypertension in 7 studies

Activins: Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.

Research Excerpts

ExcerptRelevanceReference
"Pulmonary arterial hypertension is a progressive fatal disease that is characterized by pathological pulmonary artery remodeling, in which endothelial cell dysfunction is critically involved."1.62An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension. ( Emoto, N; Fujiyama, T; Guignabert, C; Hirata, KI; Humbert, M; Ikeda, K; Miyagawa, K; Ryanto, GRT; Tu, L; Yanagisawa, M, 2021)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's4 (57.14)2.80

Authors

AuthorsStudies
Upton, PD1
Dunmore, BJ1
Li, W1
Morrell, NW1
Humbert, M2
Yung, LM1
Yang, P1
Joshi, S1
Augur, ZM1
Kim, SSJ1
Bocobo, GA1
Dinter, T1
Troncone, L1
Chen, PS1
McNeil, ME1
Southwood, M1
Poli de Frias, S1
Knopf, J1
Rosas, IO1
Sako, D1
Pearsall, RS1
Quisel, JD1
Li, G1
Kumar, R1
Yu, PB1
Ryanto, GRT1
Ikeda, K1
Miyagawa, K1
Tu, L1
Guignabert, C1
Fujiyama, T1
Yanagisawa, M1
Hirata, KI1
Emoto, N1
Kudryashova, TV1
Shen, Y1
Pena, A1
Cronin, E1
Okorie, E1
Goncharov, DA1
Goncharova, EA1
Nold-Petry, CA1
Rudloff, I1
Baumer, Y1
Ruvo, M1
Marasco, D1
Botti, P1
Farkas, L1
Cho, SX1
Zepp, JA1
Azam, T1
Dinkel, H1
Palmer, BE1
Boisvert, WA1
Cool, CD1
Taraseviciene-Stewart, L1
Heinhuis, B1
Joosten, LA1
Dinarello, CA1
Voelkel, NF1
Nold, MF1
Yndestad, A1
Larsen, KO1
Oie, E1
Ueland, T1
Smith, C1
Halvorsen, B1
Sjaastad, I1
Skjønsberg, OH1
Pedersen, TM1
Anfinsen, OG1
Damås, JK1
Christensen, G1
Aukrust, P1
Andreassen, AK1

Reviews

1 review available for activins and Pulmonary Hypertension

ArticleYear
An emerging class of new therapeutics targeting TGF, Activin, and BMP ligands in pulmonary arterial hypertension.
    Developmental dynamics : an official publication of the American Association of Anatomists, 2023, Volume: 252, Issue:3

    Topics: Activins; Bone Morphogenetic Proteins; Cytokines; Humans; Hypertension, Pulmonary; Ligands; Pulmonar

2023

Other Studies

6 other studies available for activins and Pulmonary Hypertension

ArticleYear
Viewpoint: activin signalling inhibitors for the treatment of pulmonary arterial hypertension.
    The European respiratory journal, 2023, Volume: 62, Issue:5

    Topics: Activins; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Pulmonary Arteri

2023
ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension.
    Science translational medicine, 2020, 05-13, Volume: 12, Issue:543

    Topics: Activins; Animals; Cell Differentiation; Endothelial Cells; Hypertension, Pulmonary; Signal Transduc

2020
An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension.
    Nature communications, 2021, 03-19, Volume: 12, Issue:1

    Topics: Activins; Animals; Apoptosis; Bone Morphogenetic Protein Receptors, Type II; Disease Models, Animal;

2021
Inhibitory Antibodies against Activin A and TGF-β Reduce Self-Supported, but Not Soluble Factors-Induced Growth of Human Pulmonary Arterial Vascular Smooth Muscle Cells in Pulmonary Arterial Hypertension.
    International journal of molecular sciences, 2018, Sep-28, Volume: 19, Issue:10

    Topics: Activins; Adult; Antibodies; Cell Proliferation; Culture Media, Conditioned; Female; Humans; Hyperte

2018
IL-32 promotes angiogenesis.
    Journal of immunology (Baltimore, Md. : 1950), 2014, Jan-15, Volume: 192, Issue:2

    Topics: Activins; Animals; Apoptosis; Cells, Cultured; Endostatins; Familial Primary Pulmonary Hypertension;

2014
Elevated levels of activin A in clinical and experimental pulmonary hypertension.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 106, Issue:4

    Topics: Activins; Adult; Animals; Blood Pressure; Blotting, Western; Cell Proliferation; Cytokines; Endothel

2009
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