activins and Pulmonary Hypertension
activins has been researched along with Pulmonary Hypertension in 7 studies
Activins: Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Pulmonary arterial hypertension is a progressive fatal disease that is characterized by pathological pulmonary artery remodeling, in which endothelial cell dysfunction is critically involved." | 1.62 | An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension. ( Emoto, N; Fujiyama, T; Guignabert, C; Hirata, KI; Humbert, M; Ikeda, K; Miyagawa, K; Ryanto, GRT; Tu, L; Yanagisawa, M, 2021) |
Research
Studies (7)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (14.29) | 29.6817 |
2010's | 2 (28.57) | 24.3611 |
2020's | 4 (57.14) | 2.80 |
Authors
Authors | Studies |
---|---|
Upton, PD | 1 |
Dunmore, BJ | 1 |
Li, W | 1 |
Morrell, NW | 1 |
Humbert, M | 2 |
Yung, LM | 1 |
Yang, P | 1 |
Joshi, S | 1 |
Augur, ZM | 1 |
Kim, SSJ | 1 |
Bocobo, GA | 1 |
Dinter, T | 1 |
Troncone, L | 1 |
Chen, PS | 1 |
McNeil, ME | 1 |
Southwood, M | 1 |
Poli de Frias, S | 1 |
Knopf, J | 1 |
Rosas, IO | 1 |
Sako, D | 1 |
Pearsall, RS | 1 |
Quisel, JD | 1 |
Li, G | 1 |
Kumar, R | 1 |
Yu, PB | 1 |
Ryanto, GRT | 1 |
Ikeda, K | 1 |
Miyagawa, K | 1 |
Tu, L | 1 |
Guignabert, C | 1 |
Fujiyama, T | 1 |
Yanagisawa, M | 1 |
Hirata, KI | 1 |
Emoto, N | 1 |
Kudryashova, TV | 1 |
Shen, Y | 1 |
Pena, A | 1 |
Cronin, E | 1 |
Okorie, E | 1 |
Goncharov, DA | 1 |
Goncharova, EA | 1 |
Nold-Petry, CA | 1 |
Rudloff, I | 1 |
Baumer, Y | 1 |
Ruvo, M | 1 |
Marasco, D | 1 |
Botti, P | 1 |
Farkas, L | 1 |
Cho, SX | 1 |
Zepp, JA | 1 |
Azam, T | 1 |
Dinkel, H | 1 |
Palmer, BE | 1 |
Boisvert, WA | 1 |
Cool, CD | 1 |
Taraseviciene-Stewart, L | 1 |
Heinhuis, B | 1 |
Joosten, LA | 1 |
Dinarello, CA | 1 |
Voelkel, NF | 1 |
Nold, MF | 1 |
Yndestad, A | 1 |
Larsen, KO | 1 |
Oie, E | 1 |
Ueland, T | 1 |
Smith, C | 1 |
Halvorsen, B | 1 |
Sjaastad, I | 1 |
Skjønsberg, OH | 1 |
Pedersen, TM | 1 |
Anfinsen, OG | 1 |
Damås, JK | 1 |
Christensen, G | 1 |
Aukrust, P | 1 |
Andreassen, AK | 1 |
Reviews
1 review available for activins and Pulmonary Hypertension
Article | Year |
---|---|
An emerging class of new therapeutics targeting TGF, Activin, and BMP ligands in pulmonary arterial hypertension.
Topics: Activins; Bone Morphogenetic Proteins; Cytokines; Humans; Hypertension, Pulmonary; Ligands; Pulmonar | 2023 |
Other Studies
6 other studies available for activins and Pulmonary Hypertension
Article | Year |
---|---|
Viewpoint: activin signalling inhibitors for the treatment of pulmonary arterial hypertension.
Topics: Activins; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Pulmonary Arteri | 2023 |
ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension.
Topics: Activins; Animals; Cell Differentiation; Endothelial Cells; Hypertension, Pulmonary; Signal Transduc | 2020 |
An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension.
Topics: Activins; Animals; Apoptosis; Bone Morphogenetic Protein Receptors, Type II; Disease Models, Animal; | 2021 |
Inhibitory Antibodies against Activin A and TGF-β Reduce Self-Supported, but Not Soluble Factors-Induced Growth of Human Pulmonary Arterial Vascular Smooth Muscle Cells in Pulmonary Arterial Hypertension.
Topics: Activins; Adult; Antibodies; Cell Proliferation; Culture Media, Conditioned; Female; Humans; Hyperte | 2018 |
IL-32 promotes angiogenesis.
Topics: Activins; Animals; Apoptosis; Cells, Cultured; Endostatins; Familial Primary Pulmonary Hypertension; | 2014 |
Elevated levels of activin A in clinical and experimental pulmonary hypertension.
Topics: Activins; Adult; Animals; Blood Pressure; Blotting, Western; Cell Proliferation; Cytokines; Endothel | 2009 |