activins has been researched along with Pancreatic Neoplasms in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (16.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 9 (36.00) | 24.3611 |
| 2020's | 8 (32.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bedi, K; Crawford, HC; Dou, Y; Ge, K; Gu, Y; Jeyarajan, S; Jin, L; Kim, HS; Ljungman, M; Lu, S; Narayanan, IV; Pasca di Magliano, M; Paulsen, MT; Schechter, S; Shi, J; Wei, S; Yang, J; Yi, Z | 1 |
| Caffrey, TC; Chung, S; Eldani, M; Grandgenett, PM; Hollingsworth, MA; Kattamuri, C; Kim, SY; Luan, Y; O'Connell, KA; Shukla, SK; Singh, PK; Thompson, TB; Xu, PC; You, M; Yu, SY | 1 |
| Koniaris, LG; Liu, S; Liu, Y; Narasimhan, A; Shahda, S; Silverman, LM; Wan, J; Young, AR; Zhong, X; Zimmers, TA | 1 |
| Chang, CC; Chang, MC; Chang, YT; Chen, YI; Hsu, MF; Hu, CM; Jeng, YM; Lee, WH; Tien, YW | 1 |
| Babaniamansour, S; Bedi, K; Cao, Y; Crawford, H; di Magliano, MP; Dou, Y; Ge, K; Gu, Y; Jeyarajan, S; Kim, HS; Ljungman, M; Lu, S; Magnuson, B; Narayanan, IV; Paulsen, MT; Qiu, P; Shameon, S; Shi, J; Thomas, D; Xu, C; Yang, B; Yang, J; Yi, Z; Zhao, L | 1 |
| Hanahan, D; Michael, IP; Saghafinia, S | 1 |
| Bachy, S; Bernard, D; Bertolino, P; Chanal, M; Collin, G; Flaman, JM; Goehrig, D; Guillaumond, F; Hennino, A; Pasternack, A; Principe, M; Ritvos, O; Tomasini, R; Vasseur, S; Wu, Z; Zhao, Y; Ziverec, A | 1 |
| Borkowska, A; Malecka-Panas, E; Olakowski, M; Talar-Wojnarowska, R; Wozniak, M | 1 |
| Bauer, J; Castellanos, K; Dawson, D; Grimaldo, S; Grippo, P; Guzman, G; Hwang, R; Jung, B; Krett, N; Mancinelli, G; McKinney, R; Torres, C | 1 |
| Hanahan, D; Marinoni, I; Michael, IP; Perren, A; Saghafinia, S; Tichet, M; Zangger, N | 1 |
| Ceppa, EP; Couch, ME; House, MG; Jiang, G; Jiang, Y; Koniaris, LG; Liu, J; Liu, Y; Nakeeb, A; Poirier, C; Pons, M; Sandusky, GE; Schmidt, CM; Shahda, S; Zhong, X; Zimmers, TA; Zyromski, NJ | 1 |
| de Velasco, MA; Fujita, Y; Hayashi, H; Kitano, M; Kogita, A; Kudo, M; Nishio, K; Okuno, K; Sakai, K; Sakamoto, H; Terashima, M; Togashi, Y; Tomida, S | 1 |
| Alcala, S; Azevedo, MM; Cañamero, M; Cioffi, M; Erkan, M; Garcia, E; García-Silva, S; Gomez-Lopez, G; Heeschen, C; Hermann, PC; Hidalgo, M; Kleeff, J; Miranda-Lorenzo, I; Sainz, B; Sanchez-Ripoll, Y; Sancho, P; Tatari, M | 1 |
| Aicher, A; Cioffi, M; Dorado, J; Hahn, S; Heeschen, C; Hidalgo, M; Lonardo, E; Miranda-Lorenzo, I; Ramirez, JC; Reis Vieira, C; Sainz, B; Sanchez-Ripoll, Y; Trabulo, SM | 1 |
| Andersson, O; Bertolino, P; Bonnavion, R; Charbord, J; Cordier-Bussat, M; Goehrig, D; Hennino, A; Jaafar, R; Ripoche, D; Ritvos, O; Teinturier, R; Zhang, CX | 1 |
| Bergmann, W; Carrasco, MC; Costa, IG; Eiseler, T; Genze, F; Hafner, S; Hermann, PC; Hohwieler, M; Holzmann, KH; Illing, A; Kleger, A; Köhntop, R; Liebau, S; Lin, Q; Müller, M; Perkhofer, L; Seufferlein, T; Wagner, M; Walter, K; Zenke, M | 1 |
| Aicher, A; Alcala, S; Balic, A; Bartenstein, P; Berger, F; Cebrián, DÁ; Garcia, E; Heeschen, C; Hermann, PC; Heuchel, R; Hidalgo, M; Huber, S; Löhr, M; Lonardo, E; Miranda-Lorenzo, I; Mueller, MT; Ramirez, JC; Rodriguez-Arabaolaza, I; Torres-Ruíz, R; Zagorac, S | 1 |
| Bassi, C; Beghelli, S; Bernardi, LR; Biunno, I; Bonora, A; Cattaneo, M; Ménard, S; Moore, PS; Orlandi, R; Orlandini, S; Scarpa, A; Sorio, C; Talamini, G; Zamboni, G | 1 |
| Capella, C; La Rosa, S; Lloyd, RV; Marchet, S; Uccella, S | 1 |
| Furukawa, M; Kanzaki, M; Kojima, I; Mogami, H; Nobusawa, R; Zhang, YQ | 1 |
| Kanzaki, M; Kojima, I; Miyazaki, J; Shibata, H; Takeuchi, T | 1 |
| de Winter, JP; Roelen, BA; ten Dijke, P; van den Eijnden-van Raaij, AJ; van der Burg, B | 1 |
| Büchler, MW; Friess, H; Ishiwata, T; Kleeff, J; Korc, M | 1 |
| Schiffman, MK; Sieber, S; Tikhomirov, V; Tikhomirova, S | 1 |
| Kojima, I; Mashima, H; Zhang, YQ | 1 |
25 other study(ies) available for activins and Pancreatic Neoplasms
| Article | Year |
|---|---|
KDM6A Regulates Cell Plasticity and Pancreatic Cancer Progression by Noncanonical Activin Pathway.
Topics: Activins; Animals; Cell Plasticity; Histone Demethylases; Humans; Mice; Pancreas; Pancreatic Neoplasms | 2022 |
Visceral adipose tissue remodeling in pancreatic ductal adenocarcinoma cachexia: the role of activin A signaling.
Topics: Activins; Adipocytes, White; Adiposity; Animals; Atrophy; Carcinoma, Pancreatic Ductal; Case-Control Studies; Cell Line; Fibrosis; Humans; Inhibin-beta Subunits; Intra-Abdominal Fat; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Staging; Pancreatic Neoplasms; Signal Transduction; Uncoupling Protein 1 | 2022 |
Sex specificity of pancreatic cancer cachexia phenotypes, mechanisms, and treatment in mice and humans: role of Activin.
Topics: Activins; Adenocarcinoma; Animals; Cachexia; Carcinoma, Pancreatic Ductal; Estradiol; Female; Follistatin-Related Proteins; Humans; Male; Mice; Muscle, Skeletal; Muscular Atrophy; Pancreatic Neoplasms; Phenotype; Sex Factors | 2022 |
Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation.
Topics: Activins; Carcinoma, Pancreatic Ductal; Cell Communication; Epithelial-Mesenchymal Transition; Humans; Myofibroblasts; Pancreatic Neoplasms; Sodium-Potassium-Exchanging ATPase | 2022 |
KMT2D links TGF-β signaling to noncanonical activin pathway and regulates pancreatic cancer cell plasticity.
Topics: Activins; Animals; Cell Line, Tumor; Cell Plasticity; Humans; Mice; MicroRNAs; Pancreatic Neoplasms; Transforming Growth Factor beta | 2023 |
A set of microRNAs coordinately controls tumorigenesis, invasion, and metastasis.
Topics: Activin Receptors, Type I; Activins; Algorithms; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Computational Biology; Doxycycline; Gene Expression Regulation, Neoplastic; Humans; LDL-Receptor Related Proteins; Liver Neoplasms; Membrane Transport Proteins; Mice; MicroRNAs; Neuroendocrine Tumors; Pancreatic Neoplasms; Prognosis; Receptors, LDL; Xenograft Model Antitumor Assays | 2019 |
Oncogene-Induced Senescence Limits the Progression of Pancreatic Neoplasia through Production of Activin A.
Topics: Activin Receptors, Type I; Activin Receptors, Type II; Activins; Animals; Carcinoma, Pancreatic Ductal; Cellular Senescence; Disease Progression; Genes, ras; Humans; Mice; Pancreatic Neoplasms; Phosphorylation; Precancerous Conditions; Proto-Oncogene Proteins p21(ras); Transcriptional Activation | 2020 |
Clinical significance of activin A and myostatin in patients with pancreatic adenocarcinoma and progressive weight loss.
Topics: Activins; Adenocarcinoma; Aged; Aged, 80 and over; Biomarkers, Tumor; Disease Progression; Female; Humans; Male; Middle Aged; Myostatin; Pancreatic Neoplasms; Prospective Studies; Weight Loss | 2020 |
Role of stromal activin A in human pancreatic cancer and metastasis in mice.
Topics: Activins; Adenocarcinoma; Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Epithelial Cells; Epithelium; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Metastasis; Pancreatic Neoplasms; Pancreatic Stellate Cells; Prognosis; Stromal Cells; Survival Analysis; Tumor Burden; Up-Regulation | 2021 |
ALK7 Signaling Manifests a Homeostatic Tissue Barrier That Is Abrogated during Tumorigenesis and Metastasis.
Topics: Activin Receptors, Type I; Activins; Animals; Apoptosis; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Transformation, Neoplastic; Female; Heterografts; Homeostasis; Humans; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, SCID; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta; Tumor Microenvironment | 2019 |
The systemic activin response to pancreatic cancer: implications for effective cancer cachexia therapy.
Topics: Activin Receptors, Type II; Activins; Animals; Biomarkers; Body Weights and Measures; Cachexia; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Disease Management; Disease Models, Animal; Gene Expression; Humans; Immunohistochemistry; Mice; Muscle Fibers, Skeletal; Muscular Atrophy; Pancreatic Neoplasms; Prognosis; Proportional Hazards Models | 2019 |
Activin signal promotes cancer progression and is involved in cachexia in a subset of pancreatic cancer.
Topics: Activins; Aged; Aged, 80 and over; Animals; Apoptosis; Biomarkers, Tumor; Blotting, Western; Cachexia; Cell Proliferation; Disease Progression; Female; Humans; Immunoenzyme Techniques; Lymphatic Metastasis; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Staging; Pancreatic Neoplasms; Prognosis; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Survival Rate; Tumor Cells, Cultured; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays | 2015 |
Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment.
Topics: Activins; Animals; Antimicrobial Cationic Peptides; Carcinogenesis; Carcinoma, Pancreatic Ductal; Cathelicidins; Cell Self Renewal; Gene Expression; Humans; Macrophages; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplastic Stem Cells; Pancreatic Neoplasms; Protein Array Analysis; Purinergic P2X Receptor Antagonists; Receptors, Formyl Peptide; Receptors, Purinergic P2X7; Signal Transduction; Tissue Array Analysis; Transforming Growth Factor beta1; Tumor Microenvironment | 2015 |
The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells.
Topics: Activins; Animals; Antimetabolites, Antineoplastic; Carcinoma, Pancreatic Ductal; Cell Cycle Checkpoints; Cell Self Renewal; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p57; Deoxycytidine; Down-Regulation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Mice; Mice, Nude; MicroRNAs; Neoplastic Stem Cells; Nodal Protein; Pancreatic Neoplasms; RNA, Long Noncoding; Signal Transduction; T-Box Domain Proteins; Transcriptome; Transforming Growth Factor beta1 | 2015 |
ActivinB Is Induced in Insulinoma To Promote Tumor Plasticity through a β-Cell-Induced Dedifferentiation.
Topics: Activins; Animals; Cell Dedifferentiation; Gene Expression Regulation, Neoplastic; Insulin; Insulin-Secreting Cells; Insulinoma; Mice, Inbred C57BL; Pancreas; Pancreatic Neoplasms; Proto-Oncogene Proteins | 2015 |
Tbx3 fosters pancreatic cancer growth by increased angiogenesis and activin/nodal-dependent induction of stemness.
Topics: AC133 Antigen; Activins; Adult; Aged; Aged, 80 and over; Apoptosis; Cell Movement; Cell Proliferation; Female; Humans; Male; Microscopy, Fluorescence; Middle Aged; Neoplastic Stem Cells; Neovascularization, Pathologic; Nodal Protein; Pancreatic Neoplasms; Phenotype; Spheroids, Cellular; T-Box Domain Proteins | 2016 |
Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.
Topics: AC133 Antigen; Activins; Animals; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Female; Gene Targeting; Glycoproteins; Humans; Mice; Mice, Nude; Neoplastic Stem Cells; Nodal Protein; Pancreatic Neoplasms; Peptides; Pluripotent Stem Cells; Signal Transduction; Spheroids, Cellular; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2011 |
SEL1L expression in pancreatic adenocarcinoma parallels SMAD4 expression and delays tumor growth in vitro and in vivo.
Topics: Activins; Adenosarcoma; Animals; DNA-Binding Proteins; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Mice; Mice, Nude; Pancreatic Neoplasms; Protein Biosynthesis; Proteins; Smad4 Protein; Trans-Activators | 2003 |
Localization of inhibins and activins in normal endocrine cells and endocrine tumors of the gut and pancreas: an immunohistochemical and in situ hybridization study.
Topics: Activins; Endocrine Gland Neoplasms; Endocrine Glands; Enteroendocrine Cells; Follistatin; Gastrointestinal Neoplasms; Humans; Immunohistochemistry; In Situ Hybridization; Inhibins; Pancreatic Neoplasms; Protein Subunits | 2004 |
Modulation of adenosine triphosphate-sensitive potassium channel and voltage-dependent calcium channel by activin A in HIT-T15 cells.
Topics: Action Potentials; Activins; Adenosine Triphosphate; Animals; Calcium Channels; Cricetinae; Electric Conductivity; Inhibins; Insulinoma; Membrane Potentials; Pancreatic Neoplasms; Potassium Channels; Tumor Cells, Cultured | 1995 |
Two distinct signaling pathways activated by activin A in glucose-responsive pancreatic beta-cell lines.
Topics: Activin Receptors; Activins; Animals; Calcium; Cell Division; Cell Line; Gene Expression; Glucose; Growth Substances; Humans; Inhibins; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Pancreatic Neoplasms; Protein Serine-Threonine Kinases; Receptors, Growth Factor; Recombinant Proteins; Signal Transduction; Thymidine; Transfection; Tumor Cells, Cultured | 1996 |
DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells.
Topics: Activins; Alternative Splicing; Amino Acid Sequence; Base Sequence; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Breast Neoplasms; Cell Division; DNA Primers; DNA-Binding Proteins; Drug Resistance, Neoplasm; Female; Gene Deletion; Genes, Tumor Suppressor; Humans; Inhibins; Luciferases; Molecular Sequence Data; Pancreatic Neoplasms; Polymerase Chain Reaction; Recombinant Fusion Proteins; Repressor Proteins; Sequence Deletion; Sequence Homology, Amino Acid; Smad4 Protein; Trans-Activators; Transcription, Genetic; Transforming Growth Factor beta; Tumor Cells, Cultured | 1997 |
Concomitant over-expression of activin/inhibin beta subunits and their receptors in human pancreatic cancer.
Topics: Activin Receptors; Activins; Adolescent; Adult; Aged; Aged, 80 and over; Blotting, Northern; Carcinoma, Ductal, Breast; Cell Differentiation; DNA Primers; Female; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization; In Vitro Techniques; Inhibins; Male; Middle Aged; Pancreatic Neoplasms; Polymerase Chain Reaction; Receptors, Growth Factor; Receptors, Peptide; Tumor Cells, Cultured; Up-Regulation | 1998 |
A pancreatic intraductal papillary mucinous tumor causing recurrent acute pancreatitis at the onset of menstrual periods.
Topics: Activins; Acute Disease; Adult; Cholangiopancreatography, Endoscopic Retrograde; Cystadenoma, Mucinous; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Inhibins; Menstrual Cycle; Pancreas; Pancreatectomy; Pancreatic Ducts; Pancreatic Neoplasms; Pancreatitis; Recurrence; Time Factors; Tomography, X-Ray Computed | 2000 |
Changes in the expression of transcription factors in pancreatic AR42J cells during differentiation into insulin-producing cells.
Topics: Activins; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; DNA, Antisense; DNA, Recombinant; Gene Expression Regulation, Neoplastic; Green Fluorescent Proteins; Hepatocyte Growth Factor; Homeodomain Proteins; Humans; Inhibins; Insulin; Islets of Langerhans; Luminescent Proteins; Microscopy, Fluorescence; Nerve Tissue Proteins; Paired Box Transcription Factors; Pancreatic Neoplasms; Recombinant Fusion Proteins; RNA, Messenger; Transcription Factors; Transfection; Tumor Cells, Cultured | 2001 |