activins and Neoplasms

activins has been researched along with Neoplasms in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.00)18.2507
2000's10 (25.00)29.6817
2010's23 (57.50)24.3611
2020's5 (12.50)2.80

Authors

AuthorsStudies
Hagg, A; Harrison, CA; O'Shea, E; Walton, KL1
Chen, D; Chen, G; Chen, P; Chen, X; Gu, Y; Leng, D; Li, X; Liu, W; Song, C; Wang, X; Wu, H; Wu, Q; Xiao, J; Xie, S; Ye, Y; Zhang, W; Zhao, Q1
Morianos, I; Papadopoulou, G; Semitekolou, M; Xanthou, G1
Falch, D; Grusch, M; Hoda, MA; Pany, L; Ries, A; Schelch, K1
Cao, Z; Glab, J; Hoogenraad, NJ; Jose, I; Osellame, LD; Puthalakath, H1
Cangkrama, M; Werner, S; Wietecha, M1
de Barsy, M; Gruson, D; Lause, P; Loumaye, A; Nachit, M; Thissen, JP; Trefois, P; van Maanen, A1
Bloxham, RD; Chakravarty, P; Das, D; Gori, I; Hill, CS; Howell, M; Jiang, M; Miller, DSJ; Saunders, RE1
Baek, JY; Hong, DS; Hong, S; Hong, YS; Hwang, IG; Jang, JS; Kim, HJ; Kim, JH; Kim, JW; Kim, SH; Kim, TY; Lee, JH; Shin, SH; Sun, S; Woo, IS1
Cui, X; Liu, Z; Lv, X; Qi, Y; Shang, S; Zhao, J1
Hanahan, D; Marinoni, I; Michael, IP; Perren, A; Saghafinia, S; Tichet, M; Zangger, N1
Cadoo, KA; Cangemi, NA; Haqq, CM; Hyman, DM; Liu, JF; Makker, V; Navarro, WH; Rasco, DW; Tao, JJ1
Loumaye, A; Thissen, JP1
Calvo, F; Conway, EM; Lei, V; O'Byrne, AM; Suresh Babu, S; Valdez, Y; Xu, A1
Castelli, G; Elvira, P; Testa, U1
Chen, JL; Colgan, TD; Gregorevic, P; Hagg, A; Harrison, CA; Qian, H; Walton, KL; Watt, MJ1
Bertona, M; Emanuele, E; Fiuza-Luces, C; Lucia, A; Morales, JS; Pareja-Galeano, H; Sanchis-Gomar, F1
Chen, W; Ten Dijke, P1
Moses, HL; Owens, P; Pickup, MW1
Jiang, FX; Katik, I; Li, H; Liu, JP; Mackenzie-Kludas, C; Nicholls, C; Zhou, S1
Katoh, M1
Boone, T; Chen, Q; Goldberg, AL; Han, HQ; Jiao, Q; Kwak, KS; Lacey, DL; Lu, J; Rosenfeld, R; Simonet, WS; Song, Y; Wang, JL; Zhou, X1
Vanchieri, C1
Mathew, SJ1
de Kretser, D; Henrik-Heldin, C1
Dautry, F; Havard, M; Tchénio, T1
Caja, L; Kahata, K; Moustakas, A1
Fearon, KC; Glass, DJ; Guttridge, DC1
Antsiferova, M; Werner, S1
Shen, MM1
Borawski, J; Myśliwiec, M; Naumnik, B1
Gray, PC; Harrison, CA; Robertson, DM; Vale, WW1
Imamura, T; Koinuma, D; Miyazono, K1
Chang, CD; Chen, YG; Chuang, J; Chung, J; Lin, SL; Wang, Q; Ying, SY1
Cui, X; Murakami, T; Nakatani, M; Tsuchida, K; Uezumi, A1
Behringer, RR; Coerver, KA; Finegold, MJ; Kumar, TR; Lau, AL; Matzuk, MM; Shou, W1
Harada, K; Saito, S; Sakamoto, Y; Shintani, Y; Shitsukawa, K; Wakatsuki, M1
Bernard, DJ; Chapman, SC; Woodruff, TK1
Phillips, DJ1
Risbridger, GP; Robertson, DM; Schmitt, JF1

Reviews

20 review(s) available for activins and Neoplasms

ArticleYear
Activin-A in the regulation of immunity in health and disease.
    Journal of autoimmunity, 2019, Volume: 104

    Topics: Active Transport, Cell Nucleus; Activins; Animals; Autoimmune Diseases; Cell Nucleus; Dendritic Cells; Humans; Hypersensitivity; Leukocytes; Neoplasm Proteins; Neoplasms; Smad Proteins

2019
Activin A: an emerging target for improving cancer treatment?
    Expert opinion on therapeutic targets, 2020, Volume: 24, Issue:10

    Topics: Activins; Animals; Biomarkers, Tumor; Cachexia; Drug Resistance, Neoplasm; Humans; Molecular Targeted Therapy; Neoplasms; Neovascularization, Pathologic; Tumor Microenvironment

2020
Wound Repair, Scar Formation, and Cancer: Converging on Activin.
    Trends in molecular medicine, 2020, Volume: 26, Issue:12

    Topics: Activins; Animals; Biomarkers; Cicatrix; Disease Susceptibility; Fibroblasts; Humans; Neoplasms; Wound Healing

2020
Perspectives of small molecule inhibitors of activin receptor‑like kinase in anti‑tumor treatment and stem cell differentiation (Review).
    Molecular medicine reports, 2019, Volume: 19, Issue:6

    Topics: Activin Receptors; Activins; Animals; Cell Differentiation; Humans; Mesenchymal Stem Cells; Neoplasms; Signal Transduction; Small Molecule Libraries; Transforming Growth Factor beta

2019
[Role of Activin A and Myostatin in cancer cachexia].
    Annales d'endocrinologie, 2013, Volume: 74, Issue:2

    Topics: Activins; Animals; Cachexia; Humans; Mice; Mice, Knockout; Myostatin; Neoplasms

2013
Experimental and investigational therapies for chemotherapy-induced anemia.
    Expert opinion on investigational drugs, 2015, Volume: 24, Issue:11

    Topics: Activins; Anemia; Animals; Antineoplastic Agents; Disease Progression; Drug Design; Drugs, Investigational; Hematinics; Hepcidins; Humans; Neoplasms

2015
Immunoregulation by members of the TGFβ superfamily.
    Nature reviews. Immunology, 2016, 11-25, Volume: 16, Issue:12

    Topics: Activins; Animals; Bone Morphogenetic Proteins; Gene Expression Regulation; Homeostasis; Humans; Immune System; Immunomodulation; Inflammation; Multigene Family; Neoplasms; Receptors, Transforming Growth Factor beta; Signal Transduction; Transforming Growth Factor beta

2016
TGF-β, Bone Morphogenetic Protein, and Activin Signaling and the Tumor Microenvironment.
    Cold Spring Harbor perspectives in biology, 2017, May-01, Volume: 9, Issue:5

    Topics: Activins; Animals; Bone Morphogenetic Proteins; Humans; Neoplasms; Signal Transduction; Transforming Growth Factor beta; Tumor Microenvironment

2017
Context-dependent action of transforming growth factor β family members on normal and cancer stem cells.
    Current pharmaceutical design, 2012, Volume: 18, Issue:27

    Topics: Activins; Adult; Adult Stem Cells; Animals; Antineoplastic Agents; Bone Morphogenetic Proteins; Disease Progression; Drug Resistance, Neoplasm; Embryonic Stem Cells; Humans; Neoplasms; Neoplastic Stem Cells; Signal Transduction; Transforming Growth Factor beta

2012
Cancer cachexia: mediators, signaling, and metabolic pathways.
    Cell metabolism, 2012, Aug-08, Volume: 16, Issue:2

    Topics: Activins; Cachexia; Humans; Interleukin-6; Lipolysis; Metabolic Networks and Pathways; Models, Biological; Muscular Atrophy; Myostatin; Neoplasms; Signal Transduction; Tumor Necrosis Factor-alpha

2012
The bright and the dark sides of activin in wound healing and cancer.
    Journal of cell science, 2012, Sep-01, Volume: 125, Issue:Pt 17

    Topics: Activins; Animals; Cicatrix; Fibrosis; Humans; Neoplasms; Signal Transduction; Wound Healing

2012
Decrypting the role of Cripto in tumorigenesis.
    The Journal of clinical investigation, 2003, Volume: 112, Issue:4

    Topics: Activins; Amino Acid Motifs; Animals; Cell Division; Epidermal Growth Factor; GPI-Linked Proteins; Humans; Intercellular Signaling Peptides and Proteins; Membrane Glycoproteins; Models, Biological; Neoplasm Proteins; Neoplasms; Nodal Protein; Signal Transduction; Transforming Growth Factor beta; Tumor Cells, Cultured

2003
[Activin A-follistatin: new cytokines, new perspectives].
    Polskie Archiwum Medycyny Wewnetrznej, 2003, Volume: 109, Issue:4

    Topics: Activins; Cytokines; Follistatin; Humans; Inhibin-beta Subunits; Kidney Diseases; Neoplasms

2003
Antagonists of activin signaling: mechanisms and potential biological applications.
    Trends in endocrinology and metabolism: TEM, 2005, Volume: 16, Issue:2

    Topics: Activins; Animals; Cachexia; Hormone Antagonists; Humans; Neoplasms; Signal Transduction; Wound Healing

2005
[TGF-beta family (TGF-beta, activin, BMP)].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 4

    Topics: Activins; Apoptosis; Bone Morphogenetic Proteins; Cell Differentiation; DNA-Binding Proteins; Fibrosis; Neoplasms; Neurons; Osteoblasts; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad Proteins; Trans-Activators; Transcription, Genetic; Transforming Growth Factor beta; Ubiquitin

2005
Activin signaling and its role in regulation of cell proliferation, apoptosis, and carcinogenesis.
    Experimental biology and medicine (Maywood, N.J.), 2006, Volume: 231, Issue:5

    Topics: Activin Receptors; Activins; Apoptosis; Cell Differentiation; Cell Proliferation; Follistatin; Humans; Neoplasms; Signal Transduction; Smad2 Protein; Smad3 Protein

2006
Signal transduction pathway through activin receptors as a therapeutic target of musculoskeletal diseases and cancer.
    Endocrine journal, 2008, Volume: 55, Issue:1

    Topics: Activin Receptors; Activins; Animals; Antineoplastic Agents; Bone Morphogenetic Proteins; Drug Delivery Systems; Epidermal Growth Factor; GPI-Linked Proteins; Humans; Intercellular Signaling Peptides and Proteins; Membrane Glycoproteins; Models, Biological; Musculoskeletal Diseases; Myostatin; Neoplasm Proteins; Neoplasms; Protein Binding; Protein Kinase Inhibitors; Signal Transduction; Transforming Growth Factor beta

2008
Transgenic models to study the roles of inhibins and activins in reproduction, oncogenesis, and development.
    Recent progress in hormone research, 1996, Volume: 51

    Topics: Activins; Animals; Growth; Inhibins; Mice; Mice, Knockout; Mice, Transgenic; Models, Biological; Neoplasms; Reproduction

1996
Mechanisms of inhibin signal transduction.
    Recent progress in hormone research, 2001, Volume: 56

    Topics: Activin Receptors; Activins; Animals; DNA, Complementary; Female; Follicle Stimulating Hormone; Gene Expression Regulation; Humans; Inhibins; Ligands; Models, Biological; Neoplasms; Prostatic Secretory Proteins; Protein Binding; Protein Isoforms; Receptors, Peptide; Reproduction; Signal Transduction; Transforming Growth Factor beta

2001
Activins and inhibins in endocrine and other tumors.
    Endocrine reviews, 2001, Volume: 22, Issue:6

    Topics: Activins; Animals; Endocrine Gland Neoplasms; Inhibins; Neoplasms; Signal Transduction; Tumor Suppressor Proteins

2001

Other Studies

20 other study(ies) available for activins and Neoplasms

ArticleYear
Targeting activins and inhibins to treat reproductive disorders and cancer cachexia.
    The Journal of endocrinology, 2023, 07-01, Volume: 258, Issue:1

    Topics: Activins; Animals; Cachexia; Female; Follicle Stimulating Hormone; Humans; Inhibins; Mice; Neoplasms; Pregnancy

2023
BRD9-mediated control of the TGF-β/Activin/Nodal pathway regulates self-renewal and differentiation of human embryonic stem cells and progression of cancer cells.
    Nucleic acids research, 2023, Nov-27, Volume: 51, Issue:21

    Topics: Activins; Cell Cycle Proteins; Cell Differentiation; Embryonic Stem Cells; Human Embryonic Stem Cells; Humans; Neoplasms; Nuclear Proteins; Transcription Factors; Transforming Growth Factor beta; Wnt Signaling Pathway

2023
Generation of reporter cell lines for factors inducing muscle wasting in cancer cachexia.
    Analytical biochemistry, 2020, 10-01, Volume: 606

    Topics: Activins; Animals; Cachexia; Cell Line, Transformed; Genes, Reporter; Green Fluorescent Proteins; Humans; Mice; Mice, Inbred C57BL; Muscular Atrophy; Myoblasts; Myostatin; Neoplasms; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases

2020
Circulating Activin A predicts survival in cancer patients.
    Journal of cachexia, sarcopenia and muscle, 2017, Volume: 8, Issue:5

    Topics: Activins; Adipose Tissue; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Body Composition; Cachexia; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Muscle, Skeletal; Neoplasm Staging; Neoplasms; Nutritional Status; Organ Size; Prognosis; Young Adult

2017
The Dynamics of TGF-β Signaling Are Dictated by Receptor Trafficking via the ESCRT Machinery.
    Cell reports, 2018, 11-13, Volume: 25, Issue:7

    Topics: Activins; Animals; Bone Morphogenetic Proteins; Cell Line; Down-Regulation; Endosomal Sorting Complexes Required for Transport; Epithelial-Mesenchymal Transition; Genome, Human; Humans; Lysosomes; Mice; Multivesicular Bodies; Neoplasms; Phosphorylation; Prognosis; Protein Transport; Proteolysis; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad2 Protein; Survival Analysis; Transforming Growth Factor beta; Ubiquitin-Protein Ligases; Up-Regulation

2018
Serum biomarkers for predicting overall survival and early mortality in older patients with metastatic solid tumors.
    Journal of geriatric oncology, 2019, Volume: 10, Issue:5

    Topics: Activins; Aged; Aged, 80 and over; Antineoplastic Agents; Biliary Tract Neoplasms; Biomarkers; C-Reactive Protein; Chemokine CXCL10; Collagen Type I; Colonic Neoplasms; Decision Trees; Female; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibronectins; Humans; Interleukin-6; Liver Neoplasms; Lung Neoplasms; Male; Mortality; Myostatin; Neoplasm Metastasis; Neoplasms; Peptides; Prognosis; Republic of Korea; Sirtuin 1; Stomach Neoplasms; Survival Rate; Vascular Endothelial Growth Factor A; Vitamin D

2019
ALK7 Signaling Manifests a Homeostatic Tissue Barrier That Is Abrogated during Tumorigenesis and Metastasis.
    Developmental cell, 2019, 05-06, Volume: 49, Issue:3

    Topics: Activin Receptors, Type I; Activins; Animals; Apoptosis; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Transformation, Neoplastic; Female; Heterografts; Homeostasis; Humans; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, SCID; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta; Tumor Microenvironment

2019
First-in-Human Phase I Study of the Activin A Inhibitor, STM 434, in Patients with Granulosa Cell Ovarian Cancer and Other Advanced Solid Tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, Sep-15, Volume: 25, Issue:18

    Topics: Activins; Antineoplastic Agents; Granulosa Cells; Humans; Maximum Tolerated Dose; Neoplasms; Ovarian Neoplasms; Treatment Outcome

2019
TGFβ-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells.
    BMC cancer, 2014, Feb-20, Volume: 14

    Topics: Activins; Animals; Antigens, CD; Antigens, Neoplasm; Bone Morphogenetic Protein 2; Cell Line, Tumor; Cytokines; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasms; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; RNA Stability; RNA, Messenger; Signal Transduction; Smad Proteins; Transforming Growth Factor beta

2014
Differential Effects of IL6 and Activin A in the Development of Cancer-Associated Cachexia.
    Cancer research, 2016, 09-15, Volume: 76, Issue:18

    Topics: Activins; Animals; Blotting, Western; Cachexia; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Neoplasms; Polymerase Chain Reaction

2016
Baicalin supplementation reduces serum biomarkers of skeletal muscle wasting and may protect against lean body mass reduction in cancer patients: Results from a pilot open-label study.
    Neuro endocrinology letters, 2016, Volume: 37, Issue:3

    Topics: Absorptiometry, Photon; Activins; Aged; Biomarkers; Body Weight; Cachexia; Endpoint Determination; Female; Flavonoids; Humans; Male; Middle Aged; Muscle, Skeletal; Muscular Atrophy; Neoplasms; NF-kappa B; Pilot Projects; Wasting Syndrome; Weight Loss

2016
Activin inhibits telomerase activity in cancer.
    Biochemical and biophysical research communications, 2009, Nov-27, Volume: 389, Issue:4

    Topics: Activins; Down-Regulation; HeLa Cells; Humans; Neoplasms; Recombinant Proteins; Telomerase; Tumor Suppressor Proteins

2009
Integrative genomic analyses of CXCR4: transcriptional regulation of CXCR4 based on TGFbeta, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors.
    International journal of oncology, 2010, Volume: 36, Issue:2

    Topics: Activins; Animals; Base Sequence; Comparative Genomic Hybridization; Conserved Sequence; DNA-Binding Proteins; Forkhead Transcription Factors; Gene Expression; Gene Expression Regulation; Hepatocyte Nuclear Factor 3-beta; Humans; Mice; Molecular Sequence Data; Neoplasms; Nodal Protein; Octamer Transcription Factor-3; Promoter Regions, Genetic; Rats; Receptors, CXCR4; Signal Transduction; SOXF Transcription Factors; Stem Cells; Transcription Factors; Transcription, Genetic; Transforming Growth Factor beta

2010
Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival.
    Cell, 2010, Aug-20, Volume: 142, Issue:4

    Topics: Activin Receptors, Type II; Activins; Animals; Anorexia; Atrophy; Cachexia; Female; Humans; Inhibins; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Myoblasts; Myocardium; Neoplasm Transplantation; Neoplasms; Signal Transduction; Transplantation, Heterologous; Tumor Necrosis Factor-alpha

2010
Cachexia in cancer: is it treatable at the molecular level?
    Journal of the National Cancer Institute, 2010, Nov-17, Volume: 102, Issue:22

    Topics: Activins; Cachexia; Humans; Muscle, Skeletal; Myostatin; Neoplasms; Receptors, Androgen

2010
InACTIVatINg cancer cachexia.
    Disease models & mechanisms, 2011, Volume: 4, Issue:3

    Topics: Activin Receptors, Type II; Activins; Animals; Cachexia; Disease Models, Animal; Humans; Mice; Muscle, Skeletal; Neoplasms; Signal Transduction; Transforming Growth Factor beta

2011
TGF-β down under 2011-the experts interviewed!
    Growth factors (Chur, Switzerland), 2011, Volume: 29, Issue:5

    Topics: Activins; Congresses as Topic; Follistatin; Humans; Inhibins; Neoplasms; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta

2011
A dormant state modulated by osmotic pressure controls clonogenicity of prostate cancer cells.
    The Journal of biological chemistry, 2011, Dec-23, Volume: 286, Issue:51

    Topics: Activins; Animals; Cell Cycle; Cell Line, Tumor; Culture Media, Conditioned; Humans; Male; Mice; Neoplasm Metastasis; Neoplasms; NIH 3T3 Cells; Osmosis; Prostatic Neoplasms; Signal Transduction; Tumor Suppressor Protein p53

2011
Serum immunoreactive activin A levels in normal subjects and patients with various diseases.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:6

    Topics: Activins; Adult; Aged; Aged, 80 and over; Aging; Endocrine System Diseases; Female; Growth Substances; Humans; Inhibins; Liver Diseases; Male; Middle Aged; Neoplasms; Pregnancy; Radioimmunoassay; Reference Values; Sex Characteristics

1996
New developments in the biology of inhibins, activins and follistatins.
    Trends in endocrinology and metabolism: TEM, 2001, Volume: 12, Issue:3

    Topics: Activin Receptors; Activins; Animals; Cell Division; Female; Follistatin; Glycoproteins; Humans; Inflammation; Inhibins; Neoplasms; Pituitary-Adrenal System; Pregnancy; Receptors, Growth Factor; Receptors, Peptide; Wound Healing

2001