Page last updated: 2024-10-31

activins and Muscular Dystrophy

activins has been researched along with Muscular Dystrophy in 2 studies

Activins: Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.

Research Excerpts

ExcerptRelevanceReference
" In the mdx model, engineered follistatin was dosed for 12 weeks in two studies comparing to an Fc fusion of the activin IIB receptor or an anti-myostatin antibody."1.48Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone. ( Comeau, R; Crooker, R; Deng, Q; Derakhchan, K; Dumas, J; Ehmann, DE; Huang, Y; Iskenderian, A; Kastrapeli, N; Liu, N; Lundberg, D; Norton, A; Palmieri, K; Pan, J; Pescatore, B; Romashko, A; Rong, H; Shen, C, 2018)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Ninfali, C1
Siles, L1
Esteve-Codina, A1
Postigo, A1
Iskenderian, A1
Liu, N1
Deng, Q1
Huang, Y1
Shen, C1
Palmieri, K1
Crooker, R1
Lundberg, D1
Kastrapeli, N1
Pescatore, B1
Romashko, A1
Dumas, J1
Comeau, R1
Norton, A1
Pan, J1
Rong, H1
Derakhchan, K1
Ehmann, DE1

Other Studies

2 other studies available for activins and Muscular Dystrophy

ArticleYear
The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2.
    Cell reports, 2023, 10-31, Volume: 42, Issue:10

    Topics: Activins; Animals; Cell Differentiation; Cell Lineage; Human Embryonic Stem Cells; Humans; Mice; Mus

2023
Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone.
    Skeletal muscle, 2018, 10-27, Volume: 8, Issue:1

    Topics: Activins; Animals; Follistatin; Hand Strength; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Mus

2018