activins has been researched along with Muscular Dystrophy in 2 studies
Activins: Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.
Excerpt | Relevance | Reference |
---|---|---|
" In the mdx model, engineered follistatin was dosed for 12 weeks in two studies comparing to an Fc fusion of the activin IIB receptor or an anti-myostatin antibody." | 1.48 | Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone. ( Comeau, R; Crooker, R; Deng, Q; Derakhchan, K; Dumas, J; Ehmann, DE; Huang, Y; Iskenderian, A; Kastrapeli, N; Liu, N; Lundberg, D; Norton, A; Palmieri, K; Pan, J; Pescatore, B; Romashko, A; Rong, H; Shen, C, 2018) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 1 (50.00) | 2.80 |
Authors | Studies |
---|---|
Ninfali, C | 1 |
Siles, L | 1 |
Esteve-Codina, A | 1 |
Postigo, A | 1 |
Iskenderian, A | 1 |
Liu, N | 1 |
Deng, Q | 1 |
Huang, Y | 1 |
Shen, C | 1 |
Palmieri, K | 1 |
Crooker, R | 1 |
Lundberg, D | 1 |
Kastrapeli, N | 1 |
Pescatore, B | 1 |
Romashko, A | 1 |
Dumas, J | 1 |
Comeau, R | 1 |
Norton, A | 1 |
Pan, J | 1 |
Rong, H | 1 |
Derakhchan, K | 1 |
Ehmann, DE | 1 |
2 other studies available for activins and Muscular Dystrophy
Article | Year |
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The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2.
Topics: Activins; Animals; Cell Differentiation; Cell Lineage; Human Embryonic Stem Cells; Humans; Mice; Mus | 2023 |
Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone.
Topics: Activins; Animals; Follistatin; Hand Strength; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Mus | 2018 |