activins and Multiple Myeloma

activins has been researched along with Multiple Myeloma in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's2 (13.33)18.2507
2000's1 (6.67)29.6817
2010's10 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cui, X; Ge, J; Li, J; Liao, F; Liu, Z; Shan, Y; Sun, H; Yang, Y; Zhao, Y1
He, Y; Li, L; Tong, M; Zhang, GF; Zhang, YJ; Zhao, YT; Zhou, HY1
Cirstea, D; Eda, H; Fulciniti, M; Mahindra, A; Nemani, N; Patel, K; Raje, N; Santo, L; Scullen, T; Vallet, S; Yee, A1
Anderson, JL; Aversa, F; Bolzoni, M; Bonomini, S; Giuliani, N; Guasco, D; Roodman, GD; Silbermann, R; Storti, P; Windle, JJ; Wu, J; Zhou, D1
Purushothaman, A; Toole, BP1
Hella, H; Holien, T; Mylin, AK; Nesthus, I; Olsen, OE; Sundan, A; Turesson, I; Waage, A; Wader, KF1
Anderson, KC; Attar, E; Chauhan, D; Churchill, M; Cirstea, D; Fulciniti, M; Guimaraes, A; Hideshima, T; Mukherjee, S; Munshi, N; Patel, K; Pozzi, S; Raje, N; Santo, L; Scadden, DT; Schoonmaker, JA; Seehra, JS; Sohani, AR; Vaghela, N; Vallet, S; Weissleder, R; Weller, E; Xie, W1
Abdul, N; Arnett, TR; Baud'huin, M; Bouxsein, ML; Chantry, AD; Coulton, L; Croucher, P; Evans, H; Heath, D; Key, ML; Mulivor, AW; Pearsall, S; Seehra, J; Vanderkerken, K; Werner, ED1
Christoulas, D; Dimopoulos, MA; Eleutherakis-Papaiakovou, E; Gkotzamanidou, M; Kanellias, N; Kastritis, E; Papatheodorou, A; Terpos, E1
Dimopoulos, MA; Kastritis, E; Terpos, E1
Mikhaĭlova, AA; Petrov, RV; Stepanenko, RN1
Nishihara, T; Okahashi, N; Ueda, N1
Ikeda, Y; Kisaki, M; Koseki, T; Nishihara, T; Yamato, K1
Barda-Saad, M; Zipori, D1
Borisova, AM; Glazko, AV; Golenkov, AK1

Reviews

3 review(s) available for activins and Multiple Myeloma

ArticleYear
Prevention and treatment of myeloma bone disease.
    Current hematologic malignancy reports, 2012, Volume: 7, Issue:4

    Topics: Activins; Bone Density Conservation Agents; Bone Morphogenetic Proteins; Bone Neoplasms; Diphosphonates; Humans; Immunomodulation; Multiple Myeloma; Proteasome Inhibitors; Tumor Necrosis Factor Inhibitors; Wnt Signaling Pathway

2012
[Activin A induces apoptotic cell death of myeloma cells].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:7

    Topics: Activins; Animals; Apoptosis; Humans; Inhibins; Multiple Myeloma; Tretinoin

1996
Role of activin A in negative regulation of normal and tumor B lymphocytes.
    Journal of leukocyte biology, 2001, Volume: 69, Issue:6

    Topics: Activins; Apoptosis; B-Lymphocytes; Bone Marrow Cells; Cell Cycle; Cell Differentiation; Follistatin; Glycoproteins; Growth Inhibitors; Hematopoiesis; Hematopoietic Stem Cells; Humans; Inhibins; Intercellular Signaling Peptides and Proteins; Interleukin-6; Leukemia, Erythroblastic, Acute; Models, Biological; Multiple Myeloma; Nasal Polyps; Neoplastic Stem Cells; Signal Transduction; Stromal Cells

2001

Other Studies

12 other study(ies) available for activins and Multiple Myeloma

ArticleYear
Involvement of CHOP in activin A‑induced myeloma NS‑1 cell apoptosis.
    Oncology reports, 2019, Volume: 42, Issue:6

    Topics: Activins; Animals; Caspase 12; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Humans; Injections, Intralesional; Male; Mice; Multiple Myeloma; Protein Phosphatase 1; Transcription Factor CHOP; Up-Regulation

2019
Membrane translocation of Bruton kinase in multiple myeloma cells is associated with osteoclastogenic phenotype in bone metastatic lesions.
    Medicine, 2018, Volume: 97, Issue:2

    Topics: Activins; Agammaglobulinaemia Tyrosine Kinase; Aged; Bone Neoplasms; Cell Membrane; Chemokine CCL5; Humans; Male; Middle Aged; Multiple Myeloma; NF-kappa B; Osteogenesis; Protein-Tyrosine Kinases; RNA, Messenger; Tartrate-Resistant Acid Phosphatase

2018
Lenalidomide in combination with an activin A-neutralizing antibody: preclinical rationale for a novel anti-myeloma strategy.
    Leukemia, 2013, Volume: 27, Issue:8

    Topics: Activins; Angiogenesis Inhibitors; Antibodies, Neutralizing; Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Humans; Lenalidomide; MAP Kinase Signaling System; Multiple Myeloma; Osteoblasts; Stromal Cells; Thalidomide

2013
Bone marrow monocyte-/macrophage-derived activin A mediates the osteoclastogenic effect of IL-3 in multiple myeloma.
    Leukemia, 2014, Volume: 28, Issue:4

    Topics: Activins; Animals; Bone Diseases; Humans; Interleukin-3; Macrophages; Mice; Mice, Inbred C57BL; Monocytes; Multiple Myeloma; Osteoclasts; Osteogenesis; RANK Ligand

2014
Serglycin proteoglycan is required for multiple myeloma cell adhesion, in vivo growth, and vascularization.
    The Journal of biological chemistry, 2014, Feb-28, Volume: 289, Issue:9

    Topics: Activins; Animals; Bone Marrow Cells; Cell Adhesion; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Hyaluronan Receptors; Mice; Mice, SCID; Multiple Myeloma; Neoplasm Proteins; Neovascularization, Pathologic; Proteoglycans; RNA, Messenger; RNA, Neoplasm; Stromal Cells; Vesicular Transport Proteins

2014
Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B.
    Cell communication and signaling : CCS, 2015, Jun-06, Volume: 13

    Topics: Activin Receptors, Type I; Activin Receptors, Type II; Activins; Bone Morphogenetic Proteins; Cell Line, Tumor; Follistatin; Humans; Multiple Myeloma; Protein Interaction Maps; Signal Transduction

2015
Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Mar-16, Volume: 107, Issue:11

    Topics: Activins; Animals; Bone Marrow Cells; Cell Differentiation; Cell Line, Tumor; Down-Regulation; Enzyme Activation; Homeodomain Proteins; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Multiple Myeloma; Osteoblasts; Osteolysis; Receptors, Cell Surface; Smad2 Protein; Stromal Cells

2010
Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2010, Volume: 25, Issue:12

    Topics: Activins; Animals; Bone Neoplasms; Bone Resorption; Calcification, Physiologic; Cell Line, Tumor; HEK293 Cells; Humans; Mice; Multiple Myeloma; Neoplasm Transplantation; Organ Size; Osteoblasts; Osteogenesis; Osteolysis; Paraproteins; Recombinant Fusion Proteins; Signal Transduction; Survival Analysis; Tumor Burden

2010
Circulating activin-A is elevated in patients with advanced multiple myeloma and correlates with extensive bone involvement and inferior survival; no alterations post-lenalidomide and dexamethasone therapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:10

    Topics: Activins; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bone and Bones; Case-Control Studies; Dexamethasone; Female; Humans; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Survival Rate; Thalidomide

2012
[B-activin and immunocorrection].
    Khirurgiia, 1984, Issue:11

    Topics: Activins; Adjuvants, Immunologic; Animals; Bone Marrow; Humans; Leukemia; Lymphoma, Non-Hodgkin; Multiple Myeloma; Oligopeptides; Peptides; Swine

1984
Activin A induces apoptotic cell death.
    Biochemical and biophysical research communications, 1993, Dec-15, Volume: 197, Issue:2

    Topics: Activins; Animals; Apoptosis; Cell Line; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Follistatin; Glycoproteins; Growth Substances; Humans; Hybridomas; Inhibins; Interleukin-6; Kinetics; Lymphoma; Mice; Multiple Myeloma; Transforming Growth Factor beta; Tumor Cells, Cultured

1993
[Effect of human regulatory myelopeptides on the elaboration of a factor inhibiting leukocyte migration].
    Biulleten' eksperimental'noi biologii i meditsiny, 1988, Volume: 105, Issue:1

    Topics: Activins; Agammaglobulinemia; B-Lymphocytes; Bone Marrow; Humans; Leukocyte Migration-Inhibitory Factors; Lymphokines; Multiple Myeloma; Oligopeptides; Peptides

1988