activins has been researched along with MS (Multiple Sclerosis) in 6 studies
Activins: Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here, using experimental autoimmune encephalomyelitis, an established mouse MS model, we report that therapeutic administration of activin-A ameliorates disease severity and alleviates CNS immunopathology and demyelination, associated with decreased activation of Th17 cells." | 1.56 | Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-α-dependent pathways. ( Banos, A; Belaidi, E; Doskas, T; Garbis, SD; Kalamatas, T; Kapasa, M; Karageorgiou, K; Konstantopoulos, D; Lomenick, B; Manousopoulou, A; Morianos, I; Pan, F; Papadopoulou, G; Quintana, FJ; Sallusto, F; Semitekolou, M; Trochoutsou, AI; Wei, P; Xanthou, G, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morianos, I | 1 |
| Trochoutsou, AI | 1 |
| Papadopoulou, G | 1 |
| Semitekolou, M | 1 |
| Banos, A | 1 |
| Konstantopoulos, D | 1 |
| Manousopoulou, A | 1 |
| Kapasa, M | 1 |
| Wei, P | 1 |
| Lomenick, B | 1 |
| Belaidi, E | 1 |
| Kalamatas, T | 1 |
| Karageorgiou, K | 1 |
| Doskas, T | 1 |
| Sallusto, F | 1 |
| Pan, F | 1 |
| Garbis, SD | 1 |
| Quintana, FJ | 1 |
| Xanthou, G | 1 |
| Wu, B | 1 |
| Zhang, S | 1 |
| Guo, Z | 1 |
| Bi, Y | 1 |
| Zhou, M | 1 |
| Li, P | 1 |
| Seyedsadr, M | 1 |
| Xu, X | 1 |
| Li, JL | 1 |
| Markovic-Plese, S | 1 |
| Wan, YY | 1 |
| Picón, C | 1 |
| Tejeda-Velarde, A | 1 |
| Fernández-Velasco, JI | 1 |
| Comabella, M | 1 |
| Álvarez-Lafuente, R | 1 |
| Quintana, E | 1 |
| Sainz de la Maza, S | 1 |
| Monreal, E | 1 |
| Villarrubia, N | 1 |
| Álvarez-Cermeño, JC | 1 |
| Domínguez-Mozo, MI | 1 |
| Ramió-Torrentà, L | 1 |
| Rodríguez-Martín, E | 1 |
| Roldán, E | 1 |
| Aladro, Y | 1 |
| Medina, S | 1 |
| Espiño, M | 1 |
| Masjuan, J | 1 |
| Matute-Blanch, C | 1 |
| Muñoz-San Martín, M | 1 |
| Espejo, C | 1 |
| Guaza, C | 1 |
| Muriel, A | 1 |
| Costa-Frossard, L | 1 |
| Villar, LM | 1 |
| Gusev, EI | 1 |
| Demina, TL | 1 |
| Boĭko, AN | 1 |
| Popova, NF | 1 |
| Stepanenko, RN | 2 |
| Cheknev, SB | 1 |
| Latysheva, OL | 1 |
| Denisov, LA | 1 |
| Ershov, FI | 1 |
| Petrov, RV | 1 |
| Borisova, AM | 1 |
| Glazko, AV | 1 |
| Simonova, AV | 1 |
1 trial available for activins and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
[Results of clinico-immunological testing of myelopid in chronic forms of multiple sclerosis].
Topics: Activins; Adjuvants, Immunologic; Adolescent; Adult; Double-Blind Method; Drug Administration Schedu | 1992 |
5 other studies available for activins and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-α-dependent pathways.
Topics: 5'-Nucleotidase; Activins; Animals; Antigens, CD; Apyrase; Cell Differentiation; Encephalomyelitis, | 2020 |
The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation.
Topics: Activin Receptors, Type I; Activins; Animals; Cell Differentiation; Cells, Cultured; Encephalomyelit | 2021 |
Identification of the Immunological Changes Appearing in the CSF During the Early Immunosenescence Process Occurring in Multiple Sclerosis.
Topics: Activins; Adolescent; Adult; Aged; Antibodies, Viral; B-Lymphocytes; B7-H1 Antigen; Biomarkers; Chit | 2021 |
[Interactions of interferon with other immunomodulators in the regulation of human natural killer cell activity].
Topics: Activins; Adjuvants, Immunologic; Bone Marrow; Drug Combinations; Drug Interactions; Enkephalin, Leu | 1992 |
[Efficacy of myelopid in immunodeficiency states].
Topics: Activins; Adjuvants, Immunologic; Adolescent; Adult; Agammaglobulinemia; B-Lymphocytes; Bronchitis; | 1990 |