activins has been researched along with Invasiveness, Neoplasm in 21 studies
Activins: Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malignant mesothelioma is an asbestos exposure related tumor affecting mainly pleura and it usually has a dismal prognosis." | 1.42 | Overexpression of activin-A and -B in malignant mesothelioma - attenuated Smad3 signaling responses and ERK activation promote cell migration and invasive growth. ( Koli, K; Myllärniemi, M; Pasternack, A; Ritvos, O; Rönty, M; Sutinen, E; Tamminen, JA; Yin, M, 2015) |
| "Using Barrett's esophagus cells, CPB, and the esophageal adenocarcinoma cell lines OE33 and FLO-1, we showed that Activin reduces colony formation only in CPB cells." | 1.42 | Activin a signaling regulates cell invasion and proliferation in esophageal adenocarcinoma. ( Andl, CD; Andl, T; El-Rifai, W; Koumangoye, RB; Le Bras, GF; Loomans, HA; Quast, LL; Romero-Morales, AI; Taylor, C; Zaika, AI, 2015) |
| "Mortality from prostate cancer (PCa) is due to the formation of metastatic disease." | 1.39 | Endoglin-mediated suppression of prostate cancer invasion is regulated by activin and bone morphogenetic protein type II receptors. ( Bergan, RC; Breen, MJ; Huang, X; Liu, W; Moran, DM; Vary, CP, 2013) |
| "However, its effects on OSE and ovarian cancer cells are unknown." | 1.33 | Inhibin resistance is associated with aggressive tumorigenicity of ovarian cancer cells. ( Ethier, JF; Shaw, TJ; Steller, MD; Vanderhyden, BC, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 15 (71.43) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L | 1 |
| De Menna, M | 1 |
| Groenewoud, A | 1 |
| Thalmann, GN | 1 |
| Kruithof-de Julio, M | 1 |
| Snaar-Jagalska, BE | 1 |
| Jin, W | 1 |
| Chen, F | 1 |
| Wang, K | 1 |
| Song, Y | 1 |
| Fei, X | 1 |
| Wu, B | 1 |
| Neel, JC | 1 |
| Lebrun, JJ | 1 |
| Breen, MJ | 1 |
| Moran, DM | 1 |
| Liu, W | 1 |
| Huang, X | 1 |
| Vary, CP | 1 |
| Bergan, RC | 1 |
| Liu, SG | 1 |
| Li, HC | 1 |
| Zhao, BS | 1 |
| Cao, F | 1 |
| Kelner, N | 1 |
| Rodrigues, PC | 2 |
| Bufalino, A | 3 |
| Fonseca, FP | 2 |
| Santos-Silva, AR | 1 |
| Miguel, MC | 2 |
| Pinto, CA | 1 |
| Leme, AF | 1 |
| Graner, E | 3 |
| Salo, T | 2 |
| Kowalski, LP | 2 |
| Coletta, RD | 3 |
| Le Bras, GF | 2 |
| Loomans, HA | 2 |
| Taylor, CJ | 1 |
| Revetta, FL | 1 |
| Andl, CD | 2 |
| Wacker, I | 2 |
| Behrens, J | 2 |
| Tamminen, JA | 1 |
| Yin, M | 1 |
| Rönty, M | 1 |
| Sutinen, E | 1 |
| Pasternack, A | 1 |
| Ritvos, O | 1 |
| Myllärniemi, M | 1 |
| Koli, K | 1 |
| Sainz, B | 1 |
| Alcala, S | 1 |
| Garcia, E | 1 |
| Sanchez-Ripoll, Y | 1 |
| Azevedo, MM | 1 |
| Cioffi, M | 1 |
| Tatari, M | 1 |
| Miranda-Lorenzo, I | 1 |
| Hidalgo, M | 1 |
| Gomez-Lopez, G | 1 |
| Cañamero, M | 1 |
| Erkan, M | 1 |
| Kleeff, J | 1 |
| García-Silva, S | 1 |
| Sancho, P | 1 |
| Hermann, PC | 1 |
| Heeschen, C | 1 |
| Cervigne, NK | 1 |
| de Oliveira, CE | 1 |
| Macedo, CC | 1 |
| Sobral, LM | 2 |
| Lopes, MA | 2 |
| Paes Leme, AF | 1 |
| Lambert, DW | 1 |
| Salo, TA | 1 |
| Taylor, C | 1 |
| Koumangoye, RB | 1 |
| Romero-Morales, AI | 1 |
| Quast, LL | 1 |
| Zaika, AI | 1 |
| El-Rifai, W | 1 |
| Andl, T | 1 |
| Nana, AW | 1 |
| Yang, PM | 1 |
| Lin, HY | 1 |
| Hoda, MA | 1 |
| Rozsas, A | 1 |
| Lang, E | 1 |
| Klikovits, T | 1 |
| Lohinai, Z | 1 |
| Torok, S | 1 |
| Berta, J | 1 |
| Bendek, M | 1 |
| Berger, W | 1 |
| Hegedus, B | 1 |
| Klepetko, W | 1 |
| Renyi-Vamos, F | 1 |
| Grusch, M | 1 |
| Dome, B | 1 |
| Laszlo, V | 1 |
| Sachs, M | 1 |
| Knaup, K | 1 |
| Wiesener, M | 1 |
| Weiske, J | 1 |
| Huber, O | 1 |
| Akçetin, Z | 1 |
| Bilandzic, M | 1 |
| Chu, S | 1 |
| Farnworth, PG | 1 |
| Harrison, C | 1 |
| Nicholls, P | 1 |
| Wang, Y | 1 |
| Escalona, RM | 1 |
| Fuller, PJ | 1 |
| Findlay, JK | 1 |
| Stenvers, KL | 1 |
| Meyer, MJ | 1 |
| Fleming, JM | 1 |
| Ali, MA | 1 |
| Pesesky, MW | 1 |
| Ginsburg, E | 1 |
| Vonderhaar, BK | 1 |
| Chang, KP | 1 |
| Kao, HK | 1 |
| Liang, Y | 1 |
| Cheng, MH | 1 |
| Chang, YL | 1 |
| Liu, SC | 1 |
| Lin, YC | 1 |
| Ko, TY | 1 |
| Lee, YS | 1 |
| Tsai, CL | 1 |
| Wang, TH | 1 |
| Hao, SP | 1 |
| Tsai, CN | 1 |
| Yoshinaga, K | 1 |
| Inoue, H | 1 |
| Utsunomiya, T | 1 |
| Sonoda, H | 1 |
| Masuda, T | 1 |
| Mimori, K | 1 |
| Tanaka, Y | 1 |
| Mori, M | 1 |
| Steller, MD | 1 |
| Shaw, TJ | 1 |
| Vanderhyden, BC | 1 |
| Ethier, JF | 1 |
1 review available for activins and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Overview of Transforming Growth Factor β Superfamily Involvement in Glioblastoma Initiation and Progression.
Topics: Activins; Animals; Bone Morphogenetic Proteins; Brain Neoplasms; Disease Progression; Epithelial-Mes | 2015 |
20 other studies available for activins and Invasiveness, Neoplasm
| Article | Year |
|---|---|
A NF-ĸB-Activin A signaling axis enhances prostate cancer metastasis.
Topics: Activins; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, | 2020 |
miR-15a/miR-16 cluster inhibits invasion of prostate cancer cells by suppressing TGF-β signaling pathway.
Topics: Activins; Animals; Cadherins; Cell Line; Cell Line, Tumor; Down-Regulation; Epithelial-Mesenchymal T | 2018 |
Activin and TGFβ regulate expression of the microRNA-181 family to promote cell migration and invasion in breast cancer cells.
Topics: Activins; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Fema | 2013 |
Endoglin-mediated suppression of prostate cancer invasion is regulated by activin and bone morphogenetic protein type II receptors.
Topics: Activin Receptors, Type II; Activins; Antigens, CD; Bone Morphogenetic Protein Receptors, Type II; C | 2013 |
[Expression of activin A in tissue and serum of patients with esophageal squamous cell carcinoma and its clinical significance].
Topics: Activins; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Esophageal Neoplasms; Esophageal | 2013 |
Activin A immunoexpression as predictor of occult lymph node metastasis and overall survival in oral tongue squamous cell carcinoma.
Topics: Activins; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Immunohistochemis | 2015 |
Activin A balance regulates epithelial invasiveness and tumorigenesis.
Topics: Activins; Animals; Carcinogenesis; Carcinoma, Squamous Cell; Cells, Cultured; Esophageal Neoplasms; | 2014 |
Activin B antagonizes RhoA signaling to stimulate mesenchymal morphology and invasiveness of clear cell renal cell carcinomas.
Topics: Actins; Activins; Carcinoma, Renal Cell; Cell Line, Tumor; Gene Knockdown Techniques; HEK293 Cells; | 2014 |
Overexpression of activin-A and -B in malignant mesothelioma - attenuated Smad3 signaling responses and ERK activation promote cell migration and invasive growth.
Topics: Activin Receptors, Type I; Activin Receptors, Type II; Activins; Aged; Cell Movement; Enzyme Activat | 2015 |
Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment.
Topics: Activins; Animals; Antimicrobial Cationic Peptides; Carcinogenesis; Carcinoma, Pancreatic Ductal; Ca | 2015 |
Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor Prognosis.
Topics: Activins; Adult; Aged; Apoptosis; Carcinoma, Squamous Cell; Cell Survival; Databases, Genetic; Disea | 2015 |
Activin a signaling regulates cell invasion and proliferation in esophageal adenocarcinoma.
Topics: Activins; Adenocarcinoma; Barrett Esophagus; Blotting, Western; Cell Line, Tumor; Cell Proliferation | 2015 |
High circulating activin A level is associated with tumor progression and predicts poor prognosis in lung adenocarcinoma.
Topics: Activins; Adenocarcinoma; Adenocarcinoma of Lung; Biomarkers, Tumor; Case-Control Studies; Cell Prol | 2016 |
Key role for activin B in cellular transformation after loss of the von Hippel-Lindau tumor suppressor.
Topics: Activins; Animals; Carcinoma, Renal Cell; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell | 2009 |
Loss of betaglycan contributes to the malignant properties of human granulosa tumor cells.
Topics: Activins; Cell Adhesion; Cell Line, Tumor; Female; Gene Silencing; Granulosa Cell Tumor; Humans; Inh | 2009 |
Dynamic regulation of CD24 and the invasive, CD44posCD24neg phenotype in breast cancer cell lines.
Topics: Activins; Animals; Breast Neoplasms; CD24 Antigen; Cell Line, Tumor; Female; Humans; Hyaluronan Rece | 2009 |
Overexpression of activin A in oral squamous cell carcinoma: association with poor prognosis and tumor progression.
Topics: Activins; Adult; Aged; Blotting, Western; Carcinoma, Squamous Cell; Cell Adhesion; Cell Movement; Di | 2010 |
Myofibroblasts in the stroma of oral cancer promote tumorigenesis via secretion of activin A.
Topics: Activins; Animals; Carcinoma, Squamous Cell; Cell Proliferation; Down-Regulation; Enzyme-Linked Immu | 2011 |
N-cadherin is regulated by activin A and associated with tumor aggressiveness in esophageal carcinoma.
Topics: Activins; Aged; Cadherins; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Gene Expression P | 2004 |
Inhibin resistance is associated with aggressive tumorigenicity of ovarian cancer cells.
Topics: Activins; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Collagen; DNA Primers; D | 2005 |