Page last updated: 2024-10-31

activins and Insulin Sensitivity

activins has been researched along with Insulin Sensitivity in 14 studies

Activins: Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.

Research Excerpts

ExcerptRelevanceReference
" In the total cohort, fasting plasma Fst correlated positively with fasting plasma glucose, serum insulin and C-peptide levels, homeostasis model assessment of insulin resistance, and hepatic and adipose tissue insulin resistance after adjusting for age, gender and group (all r > 0."3.96Circulating Follistatin and Activin A and Their Regulation by Insulin in Obesity and Type 2 Diabetes. ( Højlund, K; Kruse, R; Møller, PM; Richter, EA; Sylow, L; Vind, BF; Wojtaszewski, JFP, 2020)
"Preeclampsia is a major cause of maternal morbidity and mortality worldwide."2.44Novel biomarkers for predicting preeclampsia. ( Carty, DM; Delles, C; Dominiczak, AF, 2008)
"The development of insulin resistance is tightly linked to fatty liver disease and is considered a major health concern worldwide, although their mechanistic relationship remains controversial."1.39Increased activin bioavailability enhances hepatic insulin sensitivity while inducing hepatic steatosis in male mice. ( Bonomi, LM; Brown, ML; Schneyer, AL; Ungerleider, NA, 2013)
"Consequently, their role in type 2 diabetes (T2D) was examined."1.38Correlation between blood activin levels and clinical parameters of type 2 diabetes. ( Allan, CA; Chen, Y; Hedger, MP; Phillips, DJ; Wu, H; Wu, M, 2012)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's1 (7.14)29.6817
2010's10 (71.43)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Perakakis, N1
Kokkinos, A1
Peradze, N1
Tentolouris, N1
Ghaly, W1
Tsilingiris, D1
Alexandrou, A1
Mantzoros, CS1
Sylow, L1
Vind, BF1
Kruse, R1
Møller, PM1
Wojtaszewski, JFP1
Richter, EA1
Højlund, K1
Hashimoto, O2
Funaba, M2
Sekiyama, K2
Doi, S1
Shindo, D1
Satoh, R1
Itoi, H1
Oiwa, H1
Morita, M1
Suzuki, C1
Sugiyama, M1
Yamakawa, N1
Takada, H1
Matsumura, S1
Inoue, K1
Oyadomari, S1
Sugino, H1
Kurisaki, A2
Ushiro, Y1
Ungerleider, NA1
Bonomi, LM1
Brown, ML1
Schneyer, AL1
Blumensatt, M1
Greulich, S2
Herzfeld de Wiza, D1
Mueller, H2
Maxhera, B1
Rabelink, MJ1
Hoeben, RC1
Akhyari, P1
Al-Hasani, H1
Ruige, JB1
Ouwens, DM2
Boström, PA1
Fernández-Real, JM1
Nomura, M1
Morinaga, H1
Zhu, HL1
Wang, L1
Hasuzawa, N1
Takayanagi, R1
Teramoto, N1
Brandt, C1
Hansen, RH1
Hansen, JB1
Olsen, CH1
Galle, P1
Mandrup-Poulsen, T1
Gehl, J1
Pedersen, BK1
Hojman, P1
Carty, DM1
Delles, C1
Dominiczak, AF1
de Wiza, DH1
Preilowski, S1
Ding, Z1
Langin, D1
Jaquet, K1
Eckel, J1
Bonomi, L1
Brown, M1
Ungerleider, N1
Muse, M1
Matzuk, MM1
Schneyer, A1
Wu, H1
Wu, M1
Chen, Y1
Allan, CA1
Phillips, DJ1
Hedger, MP1
Laivuori, H1
Kaaja, R1
Turpeinen, U1
Stenman, UH1
Ylikorkala, O1

Reviews

1 review available for activins and Insulin Sensitivity

ArticleYear
Novel biomarkers for predicting preeclampsia.
    Trends in cardiovascular medicine, 2008, Volume: 18, Issue:5

    Topics: Activins; Angiogenesis Inducing Agents; Antigens, CD; Apolipoproteins E; Biomarkers; Endoglin; Femal

2008

Other Studies

13 other studies available for activins and Insulin Sensitivity

ArticleYear
Metabolic regulation of activins in healthy individuals and in obese patients undergoing bariatric surgery.
    Diabetes/metabolism research and reviews, 2020, Volume: 36, Issue:5

    Topics: Activins; Bariatric Surgery; Biomarkers; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Typ

2020
Circulating Follistatin and Activin A and Their Regulation by Insulin in Obesity and Type 2 Diabetes.
    The Journal of clinical endocrinology and metabolism, 2020, 05-01, Volume: 105, Issue:5

    Topics: Activins; Blood Glucose; C-Peptide; Case-Control Studies; Diabetes Mellitus, Type 2; Fasting; Female

2020
Activin E Controls Energy Homeostasis in Both Brown and White Adipose Tissues as a Hepatokine.
    Cell reports, 2018, 10-30, Volume: 25, Issue:5

    Topics: Activin Receptors, Type I; Activins; Adipocytes, Beige; Adipocytes, Brown; Adipose Tissue, Brown; Ad

2018
Activin E enhances insulin sensitivity and thermogenesis by activating brown/beige adipocytes.
    The Journal of veterinary medical science, 2019, May-11, Volume: 81, Issue:5

    Topics: Actins; Activins; Adipocytes, Beige; Adipocytes, Brown; Adipose Tissue, Brown; Adipose Tissue, White

2019
Increased activin bioavailability enhances hepatic insulin sensitivity while inducing hepatic steatosis in male mice.
    Endocrinology, 2013, Volume: 154, Issue:6

    Topics: Activins; Animals; Biological Availability; Cells, Cultured; Fatty Liver; Follistatin-Related Protei

2013
Activin A impairs insulin action in cardiomyocytes via up-regulation of miR-143.
    Cardiovascular research, 2013, Nov-01, Volume: 100, Issue:2

    Topics: Activins; Adipokines; Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies

2013
Metabolism: Irisin, the metabolic syndrome and follistatin in humans.
    Nature reviews. Endocrinology, 2014, Volume: 10, Issue:1

    Topics: Activins; Female; Fibronectins; Follistatin; Humans; Insulin Resistance; Male; Metabolic Syndrome; M

2014
Activation of activin type IB receptor signals in pancreatic β cells leads to defective insulin secretion through the attenuation of ATP-sensitive K+ channel activity.
    Biochemical and biophysical research communications, 2014, Jul-18, Volume: 450, Issue:1

    Topics: Activin Receptors, Type I; Activins; Animals; Cells, Cultured; Glucose; Insulin; Insulin Resistance;

2014
Over-expression of Follistatin-like 3 attenuates fat accumulation and improves insulin sensitivity in mice.
    Metabolism: clinical and experimental, 2015, Volume: 64, Issue:2

    Topics: Activins; Adiposity; Animals; Diet, High-Fat; Female; Follistatin-Related Proteins; Glucagon; Glucos

2015
Secretory products of guinea pig epicardial fat induce insulin resistance and impair primary adult rat cardiomyocyte function.
    Journal of cellular and molecular medicine, 2011, Volume: 15, Issue:11

    Topics: Activins; Animals; Calcium; Cardiovascular Diseases; Cells, Cultured; Diabetes Mellitus, Type 2; Die

2011
Activin B regulates islet composition and islet mass but not whole body glucose homeostasis or insulin sensitivity.
    American journal of physiology. Endocrinology and metabolism, 2012, Sep-01, Volume: 303, Issue:5

    Topics: Activins; Aging; Animals; Blood Glucose; Cell Count; Follistatin; Glucagon-Secreting Cells; Homeosta

2012
Correlation between blood activin levels and clinical parameters of type 2 diabetes.
    Experimental diabetes research, 2012, Volume: 2012

    Topics: Activins; Adult; Aged; Biomarkers; Blood Glucose; C-Reactive Protein; Diabetes Mellitus, Type 2; Fas

2012
Serum activin A and inhibin A elevated in pre-eclampsia: no relation to insulin sensitivity.
    British journal of obstetrics and gynaecology, 1999, Volume: 106, Issue:12

    Topics: Activins; Adult; Biomarkers; Female; Gestational Age; Humans; Inhibins; Insulin Resistance; Peptides

1999