activins has been researched along with Innate Inflammatory Response in 72 studies
Activins: Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Activin A belongs to the superfamily of transforming growth factor beta (TGFβ) and is a critical regulatory cytokine in breast cancer and inflammation." | 3.85 | The effects of activin A on the migration of human breast cancer cells and neutrophils and their migratory interaction. ( Cui, X; Deng, J; Feng, W; Lin, F; Liu, Z; Santos, S; Tian, G; Wu, J; Xie, D; Yang, K, 2017) |
| " Consistent with the role of activin A in regulating central nervous system inflammation and neurogenesis, intraventricular infusion of follistatin, an activin A antagonist, profoundly impaired neurogenesis and increased the number of microglia and reactive astrocytes following onset of kainic acid-induced neurodegeneration." | 3.75 | Activin A is essential for neurogenesis following neurodegeneration. ( Abdipranoto-Cowley, A; Croucher, D; Daniel, J; Galbraith, S; Henshall, S; Mervin, K; Park, JS; Vissel, B, 2009) |
| "Inflammation is a complex process regulated by a cascade of cytokines and growth factors." | 2.42 | Activin A and follistatin in systemic inflammation. ( de Kretser, DM; Jones, KL; Patella, S; Phillips, DJ, 2004) |
| "Although inflammation is known to trigger HO in FOP, the role of FOP-ACVR1A on inflammatory cells remains to be elucidated." | 1.72 | Recapitulation of pro-inflammatory signature of monocytes with ACVR1A mutation using FOP patient-derived iPSCs. ( Jin, Y; Kamakura, T; Kawai, S; Maekawa, H; Matsuda, S; Nagata, S; Nishio, M; Niwa, A; Saito, MK; Toguchida, J; Yoshitomi, H, 2022) |
| "Here, using experimental autoimmune encephalomyelitis, an established mouse MS model, we report that therapeutic administration of activin-A ameliorates disease severity and alleviates CNS immunopathology and demyelination, associated with decreased activation of Th17 cells." | 1.56 | Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-α-dependent pathways. ( Banos, A; Belaidi, E; Doskas, T; Garbis, SD; Kalamatas, T; Kapasa, M; Karageorgiou, K; Konstantopoulos, D; Lomenick, B; Manousopoulou, A; Morianos, I; Pan, F; Papadopoulou, G; Quintana, FJ; Sallusto, F; Semitekolou, M; Trochoutsou, AI; Wei, P; Xanthou, G, 2020) |
| "Silent coronary artery disease is a frequent complication of type 2 diabetes (T2DM)." | 1.38 | Activin A and cardiovascular disease in type 2 diabetes mellitus. ( Aakhus, S; Aukrust, P; Birkeland, KI; Endresen, K; Gullestad, L; Johansen, OE; Smith, C; Ueland, T, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (6.94) | 18.2507 |
| 2000's | 15 (20.83) | 29.6817 |
| 2010's | 47 (65.28) | 24.3611 |
| 2020's | 5 (6.94) | 2.80 |
| Authors | Studies |
|---|---|
| Waltereit-Kracke, V | 1 |
| Wehmeyer, C | 1 |
| Beckmann, D | 1 |
| Werbenko, E | 1 |
| Reinhardt, J | 1 |
| Geers, F | 1 |
| Dienstbier, M | 1 |
| Fennen, M | 1 |
| Intemann, J | 1 |
| Paruzel, P | 1 |
| Korb-Pap, A | 1 |
| Pap, T | 1 |
| Dankbar, B | 1 |
| Maekawa, H | 1 |
| Jin, Y | 1 |
| Nishio, M | 1 |
| Kawai, S | 1 |
| Nagata, S | 1 |
| Kamakura, T | 1 |
| Yoshitomi, H | 1 |
| Niwa, A | 1 |
| Saito, MK | 1 |
| Matsuda, S | 1 |
| Toguchida, J | 1 |
| Luo, Y | 1 |
| Cheng, YW | 1 |
| Yu, CY | 1 |
| Liu, RM | 1 |
| Zhao, YJ | 1 |
| Chen, DX | 1 |
| Zhong, JJ | 1 |
| Xiao, JH | 1 |
| Takei, Y | 1 |
| Takahashi, S | 1 |
| Nakasatomi, M | 1 |
| Sakairi, T | 1 |
| Ikeuchi, H | 1 |
| Kaneko, Y | 1 |
| Hiromura, K | 1 |
| Nojima, Y | 1 |
| Maeshima, A | 1 |
| Morianos, I | 1 |
| Trochoutsou, AI | 1 |
| Papadopoulou, G | 1 |
| Semitekolou, M | 4 |
| Banos, A | 1 |
| Konstantopoulos, D | 1 |
| Manousopoulou, A | 1 |
| Kapasa, M | 1 |
| Wei, P | 1 |
| Lomenick, B | 1 |
| Belaidi, E | 1 |
| Kalamatas, T | 1 |
| Karageorgiou, K | 1 |
| Doskas, T | 1 |
| Sallusto, F | 1 |
| Pan, F | 1 |
| Garbis, SD | 1 |
| Quintana, FJ | 1 |
| Xanthou, G | 4 |
| Ebering, A | 1 |
| Waisman, A | 1 |
| Estrada-Capetillo, L | 2 |
| Aragoneses-Fenoll, L | 1 |
| Domínguez-Soto, Á | 3 |
| Fuentelsaz-Romero, S | 1 |
| Nieto, C | 6 |
| Simón-Fuentes, M | 2 |
| Alonso, B | 2 |
| Portolés, P | 1 |
| Corbí, AL | 7 |
| Rojo, JM | 1 |
| Puig-Kröger, A | 4 |
| Planavila, A | 1 |
| Fernández-Solà, J | 1 |
| Villarroya, F | 1 |
| Xie, D | 1 |
| Liu, Z | 1 |
| Wu, J | 1 |
| Feng, W | 1 |
| Yang, K | 1 |
| Deng, J | 1 |
| Tian, G | 1 |
| Santos, S | 1 |
| Cui, X | 1 |
| Lin, F | 1 |
| Curzytek, K | 1 |
| Kubera, M | 1 |
| Trojan, E | 1 |
| Wójcik, K | 1 |
| Basta-Kaim, A | 1 |
| Detka, J | 1 |
| Maes, M | 1 |
| Rygula, R | 1 |
| De Berdt, P | 1 |
| Bottemanne, P | 1 |
| Bianco, J | 1 |
| Alhouayek, M | 1 |
| Diogenes, A | 1 |
| Llyod, A | 1 |
| Gerardo-Nava, J | 1 |
| Brook, GA | 1 |
| Miron, V | 1 |
| Muccioli, GG | 1 |
| Rieux, AD | 1 |
| Bragado, R | 2 |
| Municio, C | 2 |
| Sierra-Filardi, E | 3 |
| Escribese, MM | 2 |
| Domínguez-Andrés, J | 2 |
| Ardavín, C | 2 |
| Castrillo, A | 1 |
| Vega, MA | 5 |
| de Las Casas-Engel, M | 1 |
| Cuevas, VD | 1 |
| López-Bravo, M | 1 |
| Saz-Leal, P | 1 |
| Sancho, D | 1 |
| Ochoa-Grullón, J | 1 |
| Sánchez-Ramón, S | 1 |
| Hedger, MP | 11 |
| de Kretser, DM | 10 |
| Petrakou, E | 1 |
| Fotopoulos, S | 1 |
| Anagnostakou, M | 1 |
| Anatolitou, F | 1 |
| Samitas, K | 2 |
| Xanthou, M | 1 |
| Dong, F | 1 |
| He, X | 1 |
| Verhamme, FM | 1 |
| Bracke, KR | 1 |
| Amatngalim, GD | 1 |
| Verleden, GM | 1 |
| Van Pottelberge, GR | 1 |
| Hiemstra, PS | 1 |
| Joos, GF | 1 |
| Brusselle, GG | 1 |
| Tania, NP | 1 |
| Schmidt, M | 1 |
| Gosens, R | 1 |
| Vittorakis, S | 1 |
| Tousa, S | 1 |
| Zervas, E | 1 |
| Aggelakopoulou, M | 1 |
| Panoutsakopoulou, V | 1 |
| Gaga, M | 1 |
| Soler Palacios, B | 1 |
| Izquierdo, E | 1 |
| Criado, G | 1 |
| González-Alvaro, I | 1 |
| Sánchez-Mateos, P | 2 |
| Pablos, JL | 1 |
| Williamson, RD | 1 |
| O'Keeffe, GW | 1 |
| Kenny, LC | 1 |
| Brackmann, FA | 1 |
| Alzheimer, C | 4 |
| Trollmann, R | 1 |
| Hardy, CL | 2 |
| Rolland, JM | 1 |
| O'Hehir, RE | 2 |
| Yang, Y | 1 |
| Zhang, N | 2 |
| Crombruggen, KV | 1 |
| Lan, F | 1 |
| Hu, G | 1 |
| Hong, S | 1 |
| Bachert, C | 1 |
| Cui, B | 1 |
| Li, K | 1 |
| Gai, Z | 1 |
| She, X | 1 |
| Xu, C | 1 |
| Chen, X | 1 |
| An, G | 1 |
| Ma, Q | 1 |
| Wang, R | 1 |
| Snell, JN | 1 |
| Westall, GP | 1 |
| Snell, GI | 1 |
| Protic, O | 1 |
| Toti, P | 1 |
| Islam, MS | 1 |
| Occhini, R | 1 |
| Giannubilo, SR | 1 |
| Catherino, WH | 1 |
| Cinti, S | 1 |
| Petraglia, F | 1 |
| Ciavattini, A | 1 |
| Castellucci, M | 1 |
| Hinz, B | 1 |
| Ciarmela, P | 1 |
| González-Domínguez, É | 1 |
| Flores-Sevilla, JL | 1 |
| Pacheco-Blanco, M | 1 |
| Campos-Peña, V | 1 |
| Meraz-Ríos, MA | 1 |
| Sánchez-Torres, C | 2 |
| Canali, S | 1 |
| Core, AB | 1 |
| Zumbrennen-Bullough, KB | 1 |
| Merkulova, M | 1 |
| Wang, CY | 1 |
| Schneyer, AL | 1 |
| Pietrangelo, A | 1 |
| Babitt, JL | 1 |
| Hardy, JT | 1 |
| Buhimschi, IA | 1 |
| McCarthy, ME | 1 |
| Zhao, G | 1 |
| Laky, CA | 1 |
| Shook, LL | 1 |
| Buhimschi, CS | 1 |
| Palin, NK | 1 |
| Savikko, J | 1 |
| Pasternack, A | 1 |
| Rintala, JM | 1 |
| Kalra, B | 1 |
| Mistry, S | 1 |
| Kumar, A | 1 |
| Roth, MP | 3 |
| Helin, H | 1 |
| Ritvos, O | 1 |
| Papaporfyriou, A | 1 |
| Bakakos, P | 1 |
| Kostikas, K | 1 |
| Papatheodorou, G | 1 |
| Hillas, G | 1 |
| Trigidou, R | 1 |
| Katafigiotis, P | 1 |
| Koulouris, NG | 1 |
| Papiris, SA | 1 |
| Loukides, S | 1 |
| Chen, W | 1 |
| Ten Dijke, P | 1 |
| Besson-Fournier, C | 2 |
| Gineste, A | 1 |
| Latour, C | 2 |
| Gourbeyre, O | 1 |
| Meynard, D | 1 |
| Martin, P | 1 |
| Oswald, E | 1 |
| Coppin, H | 2 |
| Kanamori, Y | 1 |
| Sugiyama, M | 1 |
| Hashimoto, O | 1 |
| Murakami, M | 1 |
| Matsui, T | 1 |
| Funaba, M | 1 |
| Stayte, S | 1 |
| Rentsch, P | 1 |
| Tröscher, AR | 1 |
| Bamberger, M | 1 |
| Li, KM | 1 |
| Vissel, B | 2 |
| Nicolas, N | 1 |
| Michel, V | 1 |
| Bhushan, S | 1 |
| Wahle, E | 1 |
| Hayward, S | 1 |
| Ludlow, H | 1 |
| Loveland, KL | 2 |
| Schuppe, HC | 1 |
| Meinhardt, A | 1 |
| Fijak, M | 1 |
| Phillips, DJ | 11 |
| Abdipranoto-Cowley, A | 1 |
| Park, JS | 1 |
| Croucher, D | 1 |
| Daniel, J | 1 |
| Henshall, S | 1 |
| Galbraith, S | 1 |
| Mervin, K | 1 |
| Bertucci, MC | 1 |
| Loose, JM | 1 |
| Wallace, EM | 1 |
| Jenkin, G | 1 |
| Miller, SL | 1 |
| Della Bella, S | 1 |
| Giannelli, S | 1 |
| Cozzi, V | 1 |
| Signorelli, V | 1 |
| Cappelletti, M | 1 |
| Cetin, I | 1 |
| Villa, ML | 1 |
| Winnall, WR | 4 |
| Blanco, FJ | 1 |
| Palomero, MI | 1 |
| Bernabéu, C | 1 |
| Chen, Y | 2 |
| Wu, H | 2 |
| Makanji, Y | 1 |
| Smith, JA | 1 |
| Andersen, GØ | 1 |
| Ueland, T | 3 |
| Knudsen, EC | 1 |
| Scholz, H | 2 |
| Yndestad, A | 2 |
| Sahraoui, A | 1 |
| Smith, C | 3 |
| Lekva, T | 1 |
| Otterdal, K | 2 |
| Halvorsen, B | 2 |
| Seljeflot, I | 1 |
| Aukrust, P | 3 |
| Kariyawasam, HH | 1 |
| Robinson, DS | 1 |
| Aakhus, S | 1 |
| Endresen, K | 2 |
| Birkeland, KI | 1 |
| Gullestad, L | 2 |
| Johansen, OE | 1 |
| Liu, XJ | 1 |
| Zhang, FX | 1 |
| Liu, H | 1 |
| Li, KC | 1 |
| Lu, YJ | 1 |
| Wu, QF | 1 |
| Li, JY | 1 |
| Wang, B | 1 |
| Wang, Q | 1 |
| Lin, LB | 1 |
| Zhong, YQ | 1 |
| Xiao, HS | 1 |
| Bao, L | 1 |
| Zhang, X | 1 |
| Kautz, L | 1 |
| Bertrand, J | 1 |
| Ganz, T | 1 |
| Samaniego, R | 1 |
| Matsuyama, T | 1 |
| Calderon-Gómez, E | 1 |
| Salas, A | 1 |
| Sideras, P | 1 |
| Apostolou, E | 1 |
| Stavropoulos, A | 1 |
| Sountoulidis, A | 1 |
| Gavriil, A | 1 |
| Apostolidou, A | 1 |
| Andreakos, E | 1 |
| Kalin, R | 1 |
| Righi, A | 1 |
| Del Rosso, A | 1 |
| Bagchi, D | 1 |
| Generini, S | 1 |
| Cerinic, MM | 1 |
| Das, DK | 1 |
| Wankell, M | 1 |
| Werner, S | 4 |
| Waehre, T | 1 |
| Frøland, SS | 1 |
| Damås, JK | 1 |
| Jones, KL | 3 |
| Patella, S | 1 |
| Gaedeke, J | 1 |
| Boehler, T | 1 |
| Budde, K | 1 |
| Neumayer, HH | 1 |
| Peters, H | 1 |
| Xu, P | 2 |
| Van Slambrouck, C | 1 |
| Berti-Mattera, L | 1 |
| Hall, AK | 2 |
| Scutera, S | 1 |
| Riboldi, E | 1 |
| Daniele, R | 1 |
| Elia, AR | 1 |
| Fraone, T | 1 |
| Castagnoli, C | 1 |
| Giovarelli, M | 1 |
| Musso, T | 1 |
| Sozzani, S | 1 |
| Nüsing, RM | 1 |
| Barsig, J | 1 |
| Yu, J | 1 |
| Dolter, KE | 1 |
| Russell, CE | 1 |
| Brauman, JN | 2 |
| Munz, B | 1 |
| Hübner, G | 1 |
| Tretter, Y | 1 |
| Groome, NP | 1 |
| Scheerlinck, JY | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Vitamin D Deficit in Women With Uterine Fibroids[NCT04030182] | 127 participants (Actual) | Observational | 2019-12-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
21 reviews available for activins and Innate Inflammatory Response
| Article | Year |
|---|---|
Cardiokines as Modulators of Stress-Induced Cardiac Disorders.
Topics: Activins; Animals; Biomarkers; Fibroblast Growth Factors; Follistatin; Follistatin-Related Proteins; | 2017 |
The activins and their binding protein, follistatin-Diagnostic and therapeutic targets in inflammatory disease and fibrosis.
Topics: Activins; Animals; Asthma; Disease Models, Animal; Female; Fibrosis; Follistatin; Humans; Inflammati | 2013 |
Activin signalling and pre-eclampsia: from genetic risk to pre-symptomatic biomarker.
Topics: Activins; Biomarkers; Clinical Trials as Topic; Cytokines; Female; Genetic Predisposition to Disease | 2015 |
Activin A in perinatal brain injury.
Topics: Activins; Animals; Biomarkers; Brain; Brain Injuries; Female; Humans; Inflammation; Pregnancy; Strok | 2015 |
The immunoregulatory and fibrotic roles of activin A in allergic asthma.
Topics: Activins; Airway Remodeling; Animals; Asthma; Humans; Inflammation; Mice; Pulmonary Fibrosis; Signal | 2015 |
The potential role of activin and follistatin in lung transplant dysfunction.
Topics: Activins; Animals; Follistatin; Humans; Inflammation; Lung Diseases; Lung Transplantation | 2015 |
Immunoregulation by members of the TGFβ superfamily.
Topics: Activins; Animals; Bone Morphogenetic Proteins; Gene Expression Regulation; Homeostasis; Humans; Imm | 2016 |
Activin and related proteins in inflammation: not just interested bystanders.
Topics: Activins; Animals; Disease Models, Animal; Endometrium; Female; Follistatin; Humans; Inflammation; L | 2009 |
The regulation and functions of activin and follistatin in inflammation and immunity.
Topics: Activins; Animals; Follistatin; Gene Expression Regulation; Humans; Immune System; Inflammation | 2011 |
Activin-A: a novel critical regulator of allergic asthma.
Topics: Activins; Airway Remodeling; Animals; Asthma; Cytokines; Humans; Inflammation; Signal Transduction; | 2011 |
Regulation of activin and inhibin in the adult testis and the evidence for functional roles in spermatogenesis and immunoregulation.
Topics: Activins; Animals; Humans; Immunomodulation; Inflammation; Inhibins; Male; Signal Transduction; Sper | 2012 |
The roles of activin A and its binding protein, follistatin, in inflammation and tissue repair.
Topics: Activins; Animals; Fibrosis; Follistatin; Humans; Immunomodulation; Inflammation; Lymphocytes; TGF-b | 2012 |
Activin, neutrophils, and inflammation: just coincidence?
Topics: Activins; Adaptive Immunity; Animals; Gene Expression Regulation; Homeostasis; Humans; Immunity, Inn | 2013 |
The roles of activin in cytoprotection and tissue repair.
Topics: Activins; Animals; Cytoprotection; Follistatin; Inflammation; Keratinocytes; Mice; Morphogenesis; Ne | 2003 |
Activin A and follistatin in systemic inflammation.
Topics: Activins; Animals; Cytokines; Follistatin; Humans; Immunity, Cellular; Inflammation; Inhibin-beta Su | 2004 |
Activins, inhibins and follistatins in the large domestic species.
Topics: Activins; Animals; Animals, Domestic; Feedback, Physiological; Female; Follistatin; Inflammation; In | 2005 |
Roles of activin in tissue repair, fibrosis, and inflammatory disease.
Topics: Activins; Animals; Cicatrix; Cytokines; Fibrosis; Humans; Inflammation; Wound Healing | 2006 |
Production of activin A and its roles in inflammation and hematopoiesis.
Topics: Activins; Animals; Bone Marrow; Cytokines; Gene Expression Regulation; Glucocorticoids; Hematopoiesi | 1997 |
A novel role of activin in inflammation and repair.
Topics: Activins; Animals; Brain Injuries; Growth Substances; Humans; Inflammation; Inhibins; Rats; Skin; Wo | 1999 |
Activin A and follistatin: their role in the acute phase reaction and inflammation.
Topics: Activins; Acute-Phase Reaction; Follistatin; Glycoproteins; Growth Substances; Humans; Inflammation; | 1999 |
Evidence for activin A and follistatin involvement in the systemic inflammatory response.
Topics: Activins; Animals; Drug Interactions; Follistatin; Humans; Inflammation; Inhibin-beta Subunits; Sign | 2001 |
1 trial available for activins and Innate Inflammatory Response
| Article | Year |
|---|---|
Circulating conventional and plasmacytoid dendritic cell subsets display distinct kinetics during in vivo repeated allergen skin challenges in atopic subjects.
Topics: Activins; Adolescent; Adult; Allergens; Dendritic Cells; Dermatitis, Atopic; Female; Gene Expression | 2014 |
50 other studies available for activins and Innate Inflammatory Response
| Article | Year |
|---|---|
Deletion of activin A in mesenchymal but not myeloid cells ameliorates disease severity in experimental arthritis.
Topics: Activins; Animals; Arthritis, Experimental; Fibroblasts; Inflammation; Mice; Severity of Illness Ind | 2022 |
Recapitulation of pro-inflammatory signature of monocytes with ACVR1A mutation using FOP patient-derived iPSCs.
Topics: Activin Receptors, Type I; Activins; Animals; Doxycycline; Humans; Inflammation; Lipopolysaccharides | 2022 |
Effects of hyaluronic acid on differentiation of human amniotic epithelial cells and cell-replacement therapy in type 1 diabetic mice.
Topics: Activins; Amnion; Animals; Cell Culture Techniques; Cell Differentiation; Cell- and Tissue-Based The | 2019 |
Urinary Activin A is a novel biomarker reflecting renal inflammation and tubular damage in ANCA-associated vasculitis.
Topics: Activins; Aged; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Biomarkers; Biopsy; Fema | 2019 |
Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-α-dependent pathways.
Topics: 5'-Nucleotidase; Activins; Animals; Antigens, CD; Apyrase; Cell Differentiation; Encephalomyelitis, | 2020 |
Time to activin on pathogenic T cells.
Topics: Activins; Autoimmune Diseases; Inflammation; T-Lymphocytes; Virulence | 2020 |
CD28 is expressed by macrophages with anti-inflammatory potential and limits their T-cell activating capacity.
Topics: Activins; Animals; Arthritis, Rheumatoid; CD28 Antigens; Cells, Cultured; Gene Expression; Gene Expr | 2021 |
The effects of activin A on the migration of human breast cancer cells and neutrophils and their migratory interaction.
Topics: Activins; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Humans; Inflammation; Neutrophils; Tran | 2017 |
The effects of pessimism on cell-mediated immunity in rats.
Topics: Activins; Animals; Avoidance Learning; Biomarkers; Cell Proliferation; Discrimination, Psychological | 2018 |
Stem cells from human apical papilla decrease neuro-inflammation and stimulate oligodendrocyte progenitor differentiation via activin-A secretion.
Topics: Activins; Adult; Animals; Cell Differentiation; Cell Line; Demyelinating Diseases; Dental Papilla; H | 2018 |
The Activin A-Peroxisome Proliferator-Activated Receptor Gamma Axis Contributes to the Transcriptome of GM-CSF-Conditioned Human Macrophages.
Topics: Activins; Animals; Cell Differentiation; Cell Line; Culture Media, Conditioned; Gene Expression Regu | 2018 |
IVIg Promote Cross-Tolerance against Inflammatory Stimuli In Vitro and In Vivo.
Topics: Activins; Animals; Anti-Inflammatory Agents; Cells, Cultured; Chemokine CCL2; Enzyme Activation; Gra | 2018 |
Activin-A exerts a crucial anti-inflammatory role in neonatal infections.
Topics: Activins; Case-Control Studies; Chemokines; Cytokines; Humans; Infant, Newborn; Infant, Newborn, Dis | 2013 |
Activin A: a potential therapeutic target for characterizing and stopping joint pain early in rheumatoid arthritis patients.
Topics: Activins; Animals; Arthralgia; Arthritis, Rheumatoid; Biomarkers; Humans; Inflammation; Inflammation | 2014 |
Role of activin-A in cigarette smoke-induced inflammation and COPD.
Topics: Activins; Animals; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Follistatin; | 2014 |
Activin-A: active in inflammation in COPD.
Topics: Activins; Animals; Humans; Inflammation; Pulmonary Disease, Chronic Obstructive; Smoking | 2014 |
Macrophages from the synovium of active rheumatoid arthritis exhibit an activin A-dependent pro-inflammatory profile.
Topics: Activins; Adult; Aged; Arthritis, Rheumatoid; Cells, Cultured; Female; Humans; Hypoxia-Inducible Fac | 2015 |
Differential Expression and Release of Activin A and Follistatin in Chronic Rhinosinusitis with and without Nasal Polyps.
Topics: Activins; Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Extracellular Matrix Proteins | 2015 |
Chronic Noise Exposure Acts Cumulatively to Exacerbate Alzheimer's Disease-Like Amyloid-β Pathology and Neuroinflammation in the Rat Hippocampus.
Topics: Activins; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precurso | 2015 |
Possible involvement of inflammatory/reparative processes in the development of uterine fibroids.
Topics: Actins; Activins; Antigens, CD34; Collagen; Desmin; Female; Fibroblasts; Humans; Immunohistochemistr | 2016 |
Atypical Activin A and IL-10 Production Impairs Human CD16+ Monocyte Differentiation into Anti-Inflammatory Macrophages.
Topics: Activins; Blotting, Western; Cell Differentiation; Cell Separation; Flow Cytometry; Fluorescent Anti | 2016 |
Activin B Induces Noncanonical SMAD1/5/8 Signaling via BMP Type I Receptors in Hepatocytes: Evidence for a Role in Hepcidin Induction by Inflammation in Male Mice.
Topics: Activins; Animals; Bone Morphogenetic Protein Receptors, Type I; Cell Line, Tumor; Hepatocytes; Hepc | 2016 |
Imbalance of Amniotic Fluid Activin-A and Follistatin in Intraamniotic Infection, Inflammation, and Preterm Birth.
Topics: Activins; Adult; Amniotic Fluid; Chorioamnionitis; Female; Fetal Membranes, Premature Rupture; Folli | 2016 |
Activin inhibition limits early innate immune response in rat kidney allografts-a pilot study.
Topics: Activins; Allografts; Animals; Cytokines; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Humans; Im | 2017 |
Activin A and follistatin in patients with asthma. Does severity make the difference?
Topics: Activins; Adult; Aged; Airway Remodeling; Asthma; Basement Membrane; Bronchi; Bronchoalveolar Lavage | 2017 |
Hepcidin upregulation by inflammation is independent of Smad1/5/8 signaling by activin B.
Topics: Activins; Animals; Bacterial Infections; Bone Morphogenetic Protein 6; Endotoxemia; Escherichia coli | 2017 |
Regulation of hepcidin expression by inflammation-induced activin B.
Topics: Activin Receptors, Type II; Activins; Animals; Bone Morphogenetic Protein Receptors, Type I; Cattle; | 2016 |
Activin A Inhibits MPTP and LPS-Induced Increases in Inflammatory Cell Populations and Loss of Dopamine Neurons in the Mouse Midbrain In Vivo.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Activins; Animals; Cell Survival; Disease Models, Anim | 2017 |
Testicular activin and follistatin levels are elevated during the course of experimental autoimmune epididymo-orchitis in mice.
Topics: Actins; Activins; Animals; Antigens, CD; Autoimmune Diseases; Cell Count; Cytokines; Epididymitis; F | 2017 |
Activin A is essential for neurogenesis following neurodegeneration.
Topics: Activins; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Ex | 2009 |
Anti-inflammatory therapy in an ovine model of fetal hypoxia induced by single umbilical artery ligation.
Topics: Activins; Amniotic Fluid; Animals; Anti-Inflammatory Agents; Dinoprostone; Disease Models, Animal; F | 2011 |
Incomplete activation of peripheral blood dendritic cells during healthy human pregnancy.
Topics: Activins; Adult; Antigen Presentation; Cells, Cultured; Cytokines; Dendritic Cells; Female; Flow Cyt | 2011 |
Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers.
Topics: Activins; Animals; Biomarkers; Blotting, Western; Cell Differentiation; Cell Line; Cell Separation; | 2011 |
Tumour necrosis factor-α stimulates human neutrophils to release preformed activin A.
Topics: Activins; Apoptosis; Enzyme-Linked Immunosorbent Assay; Humans; Imidazoles; Inflammation; Inflammati | 2011 |
Activin A levels are associated with abnormal glucose regulation in patients with myocardial infarction: potential counteracting effects of activin A on inflammation.
Topics: Activins; Aged; Blood Glucose; Female; Glucose Tolerance Test; Humans; Immunoenzyme Techniques; Infl | 2011 |
Activin A and cardiovascular disease in type 2 diabetes mellitus.
Topics: Activins; Adult; Aged; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Cross-Se | 2012 |
Activin C expressed in nociceptive afferent neurons is required for suppressing inflammatory pain.
Topics: Activins; Animals; Behavior, Animal; Cell Count; Chronic Pain; Extracellular Signal-Regulated MAP Ki | 2012 |
Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling.
Topics: Activins; Animals; Antimicrobial Cationic Peptides; Bone Morphogenetic Protein 6; Bone Morphogenetic | 2012 |
The prolyl hydroxylase PHD3 identifies proinflammatory macrophages and its expression is regulated by activin A.
Topics: Activins; Blotting, Western; Dioxygenases; Enzyme-Linked Immunosorbent Assay; Gene Expression Regula | 2012 |
Regulation of activin A release from murine bone marrow-derived neutrophil precursors by tumour necrosis factor-α and insulin.
Topics: Activins; Animals; Bone Marrow Cells; Cells, Cultured; Glucose; Inflammation; Insulin; Male; Mice; M | 2013 |
Activin, a grape seed-derived proanthocyanidin extract, reduces plasma levels of oxidative stress and adhesion molecules (ICAM-1, VCAM-1 and E-selectin) in systemic sclerosis.
Topics: Activins; Anthocyanins; Cell Adhesion; E-Selectin; Humans; Inflammation; Intercellular Adhesion Mole | 2002 |
Potential anti-inflammatory role of activin A in acute coronary syndromes.
Topics: Activins; Angina, Unstable; Angioplasty, Balloon, Coronary; Cells, Cultured; Cytokines; DNA-Binding | 2004 |
Glomerular activin A overexpression is linked to fibrosis in anti-Thy1 glomerulonephritis.
Topics: Activins; Animals; Cells, Cultured; Disease Models, Animal; Enalapril; Fibroblast Growth Factor 2; G | 2005 |
Activin induces tactile allodynia and increases calcitonin gene-related peptide after peripheral inflammation.
Topics: Activins; Animals; Ankle; Calcitonin Gene-Related Peptide; Female; Freund's Adjuvant; Ganglia, Spina | 2005 |
Activin acts with nerve growth factor to regulate calcitonin gene-related peptide mRNA in sensory neurons.
Topics: Activins; Animals; Calcitonin Gene-Related Peptide; Cells, Cultured; Drug Synergism; Ganglia, Spinal | 2007 |
Production and function of activin A in human dendritic cells.
Topics: Activins; Cytokines; Dendritic Cells; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Follistatin | 2008 |
Inflammatory potency of activin A. Effect on prostanoid and nitric oxide formation.
Topics: Activins; Animals; Bone Marrow Cells; Cell Differentiation; Cinnamates; Cyclooxygenase 2; Dexamethas | 1997 |
Activin A regulates growth and acute phase proteins in the human liver cell line, HepG2.
Topics: Activins; Acute-Phase Proteins; Carcinoma, Hepatocellular; Cell Division; Dose-Response Relationship | 1999 |
Activin A release into the circulation is an early event in systemic inflammation and precedes the release of follistatin.
Topics: Activins; Animals; Enzyme-Linked Immunosorbent Assay; Follistatin; Glycoproteins; Inflammation; Inhi | 2000 |
New developments in the biology of inhibins, activins and follistatins.
Topics: Activin Receptors; Activins; Animals; Cell Division; Female; Follistatin; Glycoproteins; Humans; Inf | 2001 |