Compounds > activins

activins and Inflammation

activins has been researched along with Inflammation in 72 studies

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (6.94)18.2507
2000's15 (20.83)29.6817
2010's47 (65.28)24.3611
2020's5 (6.94)2.80

Authors

AuthorsStudies
Beckmann, D; Dankbar, B; Dienstbier, M; Fennen, M; Geers, F; Intemann, J; Korb-Pap, A; Pap, T; Paruzel, P; Reinhardt, J; Waltereit-Kracke, V; Wehmeyer, C; Werbenko, E1
Jin, Y; Kamakura, T; Kawai, S; Maekawa, H; Matsuda, S; Nagata, S; Nishio, M; Niwa, A; Saito, MK; Toguchida, J; Yoshitomi, H1
Chen, DX; Cheng, YW; Liu, RM; Luo, Y; Xiao, JH; Yu, CY; Zhao, YJ; Zhong, JJ1
Hiromura, K; Ikeuchi, H; Kaneko, Y; Maeshima, A; Nakasatomi, M; Nojima, Y; Sakairi, T; Takahashi, S; Takei, Y1
Banos, A; Belaidi, E; Doskas, T; Garbis, SD; Kalamatas, T; Kapasa, M; Karageorgiou, K; Konstantopoulos, D; Lomenick, B; Manousopoulou, A; Morianos, I; Pan, F; Papadopoulou, G; Quintana, FJ; Sallusto, F; Semitekolou, M; Trochoutsou, AI; Wei, P; Xanthou, G1
Ebering, A; Waisman, A1
Alonso, B; Aragoneses-Fenoll, L; Corbí, AL; Domínguez-Soto, Á; Estrada-Capetillo, L; Fuentelsaz-Romero, S; Nieto, C; Portolés, P; Puig-Kröger, A; Rojo, JM; Simón-Fuentes, M1
Fernández-Solà, J; Planavila, A; Villarroya, F1
Cui, X; Deng, J; Feng, W; Lin, F; Liu, Z; Santos, S; Tian, G; Wu, J; Xie, D; Yang, K1
Basta-Kaim, A; Curzytek, K; Detka, J; Kubera, M; Maes, M; Rygula, R; Trojan, E; Wójcik, K1
Alhouayek, M; Bianco, J; Bottemanne, P; Brook, GA; De Berdt, P; Diogenes, A; Gerardo-Nava, J; Llyod, A; Miron, V; Muccioli, GG; Rieux, AD1
Alonso, B; Ardavín, C; Bragado, R; Castrillo, A; Corbí, AL; Domínguez-Andrés, J; Escribese, MM; Municio, C; Nieto, C; Puig-Kröger, A; Sierra-Filardi, E; Vega, MA1
Ardavín, C; Corbí, AL; Cuevas, VD; de Las Casas-Engel, M; Domínguez-Andrés, J; Domínguez-Soto, Á; López-Bravo, M; Ochoa-Grullón, J; Sánchez-Ramón, S; Sancho, D; Saz-Leal, P; Simón-Fuentes, M; Vega, MA1
de Kretser, DM; Hedger, MP1
Anagnostakou, M; Anatolitou, F; Fotopoulos, S; Petrakou, E; Samitas, K; Semitekolou, M; Xanthou, G; Xanthou, M1
Dong, F; He, X1
Amatngalim, GD; Bracke, KR; Brusselle, GG; Hiemstra, PS; Joos, GF; Van Pottelberge, GR; Verhamme, FM; Verleden, GM1
Gosens, R; Schmidt, M; Tania, NP1
Aggelakopoulou, M; Gaga, M; Panoutsakopoulou, V; Samitas, K; Semitekolou, M; Tousa, S; Vittorakis, S; Xanthou, G; Zervas, E1
Corbí, AL; Criado, G; Estrada-Capetillo, L; González-Alvaro, I; Izquierdo, E; Municio, C; Nieto, C; Pablos, JL; Puig-Kröger, A; Sánchez-Mateos, P; Soler Palacios, B1
Kenny, LC; O'Keeffe, GW; Williamson, RD1
Alzheimer, C; Brackmann, FA; Trollmann, R1
Hardy, CL; O'Hehir, RE; Rolland, JM1
Bachert, C; Crombruggen, KV; Hong, S; Hu, G; Lan, F; Yang, Y; Zhang, N1
An, G; Chen, X; Cui, B; Gai, Z; Li, K; Ma, Q; She, X; Wang, R; Xu, C; Zhang, N1
Snell, GI; Snell, JN; Westall, GP1
Castellucci, M; Catherino, WH; Ciarmela, P; Ciavattini, A; Cinti, S; Giannubilo, SR; Hinz, B; Islam, MS; Occhini, R; Petraglia, F; Protic, O; Toti, P1
Campos-Peña, V; Corbí, ÁL; Domínguez-Soto, Á; Flores-Sevilla, JL; González-Domínguez, É; Meraz-Ríos, MA; Nieto, C; Pacheco-Blanco, M; Sánchez-Torres, C; Vega, MA1
Babitt, JL; Canali, S; Core, AB; Merkulova, M; Pietrangelo, A; Schneyer, AL; Wang, CY; Zumbrennen-Bullough, KB1
Buhimschi, CS; Buhimschi, IA; Hardy, JT; Laky, CA; McCarthy, ME; Shook, LL; Zhao, G1
Helin, H; Kalra, B; Kumar, A; Mistry, S; Palin, NK; Pasternack, A; Rintala, JM; Ritvos, O; Roth, MP; Savikko, J1
Bakakos, P; Hillas, G; Katafigiotis, P; Kostikas, K; Koulouris, NG; Loukides, S; Papaporfyriou, A; Papatheodorou, G; Papiris, SA; Trigidou, R1
Chen, W; Ten Dijke, P1
Besson-Fournier, C; Coppin, H; Gineste, A; Gourbeyre, O; Latour, C; Martin, P; Meynard, D; Oswald, E; Roth, MP1
Funaba, M; Hashimoto, O; Kanamori, Y; Matsui, T; Murakami, M; Sugiyama, M1
Bamberger, M; Li, KM; Rentsch, P; Stayte, S; Tröscher, AR; Vissel, B1
Bhushan, S; de Kretser, DM; Fijak, M; Hayward, S; Hedger, MP; Loveland, KL; Ludlow, H; Meinhardt, A; Michel, V; Nicolas, N; Schuppe, HC; Wahle, E1
de Kretser, DM; Hedger, MP; Phillips, DJ2
Abdipranoto-Cowley, A; Croucher, D; Daniel, J; Galbraith, S; Henshall, S; Mervin, K; Park, JS; Vissel, B1
Bertucci, MC; Jenkin, G; Loose, JM; Miller, SL; Wallace, EM1
Cappelletti, M; Cetin, I; Cozzi, V; Della Bella, S; Giannelli, S; Signorelli, V; Villa, ML1
de Kretser, DM; Hedger, MP; Phillips, DJ; Winnall, WR1
Bernabéu, C; Blanco, FJ; Bragado, R; Corbí, AL; Nieto, C; Palomero, MI; Puig-Kröger, A; Sierra-Filardi, E; Vega, MA1
Chen, Y; Hedger, MP; Loveland, KL; Makanji, Y; Phillips, DJ; Smith, JA; Winnall, WR; Wu, H1
Andersen, GØ; Aukrust, P; Halvorsen, B; Knudsen, EC; Lekva, T; Otterdal, K; Sahraoui, A; Scholz, H; Seljeflot, I; Smith, C; Ueland, T; Yndestad, A1
Kariyawasam, HH; Robinson, DS; Semitekolou, M; Xanthou, G1
Hedger, MP; Winnall, WR1
de Kretser, DM; Hardy, CL; Hedger, MP; O'Hehir, RE1
Aakhus, S; Aukrust, P; Birkeland, KI; Endresen, K; Gullestad, L; Johansen, OE; Smith, C; Ueland, T1
Bao, L; Li, JY; Li, KC; Lin, LB; Liu, H; Liu, XJ; Lu, YJ; Wang, B; Wang, Q; Wu, QF; Xiao, HS; Zhang, FX; Zhang, X; Zhong, YQ1
Bertrand, J; Besson-Fournier, C; Coppin, H; Ganz, T; Kautz, L; Latour, C; Roth, MP1
Calderon-Gómez, E; Corbí, AL; Escribese, MM; Matsuyama, T; Nieto, C; Salas, A; Samaniego, R; Sánchez-Mateos, P; Sánchez-Torres, C; Sierra-Filardi, E; Vega, MA1
Chen, Y; Hedger, MP; Phillips, DJ; Winnall, WR; Wu, H1
Andreakos, E; Apostolidou, A; Apostolou, E; Gavriil, A; Sideras, P; Sountoulidis, A; Stavropoulos, A1
Bagchi, D; Cerinic, MM; Das, DK; Del Rosso, A; Generini, S; Kalin, R; Righi, A1
Alzheimer, C; Wankell, M; Werner, S1
Aukrust, P; Damås, JK; Endresen, K; Frøland, SS; Gullestad, L; Halvorsen, B; Otterdal, K; Scholz, H; Smith, C; Ueland, T; Waehre, T; Yndestad, A1
de Kretser, DM; Jones, KL; Patella, S; Phillips, DJ1
Phillips, DJ2
Boehler, T; Budde, K; Gaedeke, J; Neumayer, HH; Peters, H1
Berti-Mattera, L; Hall, AK; Van Slambrouck, C; Xu, P1
Alzheimer, C; Werner, S1
Hall, AK; Xu, P1
Castagnoli, C; Daniele, R; Elia, AR; Fraone, T; Giovarelli, M; Musso, T; Riboldi, E; Scutera, S; Sozzani, S1
Barsig, J; Nüsing, RM1
Dolter, KE; Yu, J1
Brauman, JN; de Kretser, DM; Hedger, MP; Phillips, DJ; Russell, CE1
Alzheimer, C; Hübner, G; Munz, B; Tretter, Y; Werner, S1
Brauman, JN; de Kretser, DM; Groome, NP; Jones, KL; Phillips, DJ1
de Kretser, DM; Hedger, MP; Jones, KL; Phillips, DJ; Scheerlinck, JY1

Reviews

21 review(s) available for activins and Inflammation

ArticleYear
Cardiokines as Modulators of Stress-Induced Cardiac Disorders.
    Advances in protein chemistry and structural biology, 2017, Volume: 108

    Topics: Activins; Animals; Biomarkers; Fibroblast Growth Factors; Follistatin; Follistatin-Related Proteins; Growth Differentiation Factor 15; Heart Diseases; Humans; Inflammation; Interleukin-33; Myocardium; Myostatin; Paracrine Communication; Stress, Physiological; Transforming Growth Factor beta

2017
The activins and their binding protein, follistatin-Diagnostic and therapeutic targets in inflammatory disease and fibrosis.
    Cytokine & growth factor reviews, 2013, Volume: 24, Issue:3

    Topics: Activins; Animals; Asthma; Disease Models, Animal; Female; Fibrosis; Follistatin; Humans; Inflammation; Inhibins; Male; Wound Healing

2013
Activin signalling and pre-eclampsia: from genetic risk to pre-symptomatic biomarker.
    Cytokine, 2015, Volume: 71, Issue:2

    Topics: Activins; Biomarkers; Clinical Trials as Topic; Cytokines; Female; Genetic Predisposition to Disease; Humans; Inflammation; Oxidative Stress; Placenta; Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Risk Factors; Signal Transduction; Transforming Growth Factor beta

2015
Activin A in perinatal brain injury.
    Neuropediatrics, 2015, Volume: 46, Issue:2

    Topics: Activins; Animals; Biomarkers; Brain; Brain Injuries; Female; Humans; Inflammation; Pregnancy; Stroke

2015
The immunoregulatory and fibrotic roles of activin A in allergic asthma.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2015, Volume: 45, Issue:10

    Topics: Activins; Airway Remodeling; Animals; Asthma; Humans; Inflammation; Mice; Pulmonary Fibrosis; Signal Transduction

2015
The potential role of activin and follistatin in lung transplant dysfunction.
    Expert review of respiratory medicine, 2015, Volume: 9, Issue:6

    Topics: Activins; Animals; Follistatin; Humans; Inflammation; Lung Diseases; Lung Transplantation

2015
Immunoregulation by members of the TGFβ superfamily.
    Nature reviews. Immunology, 2016, 11-25, Volume: 16, Issue:12

    Topics: Activins; Animals; Bone Morphogenetic Proteins; Gene Expression Regulation; Homeostasis; Humans; Immune System; Immunomodulation; Inflammation; Multigene Family; Neoplasms; Receptors, Transforming Growth Factor beta; Signal Transduction; Transforming Growth Factor beta

2016
Activin and related proteins in inflammation: not just interested bystanders.
    Cytokine & growth factor reviews, 2009, Volume: 20, Issue:2

    Topics: Activins; Animals; Disease Models, Animal; Endometrium; Female; Follistatin; Humans; Inflammation; Lymphocytes; Male; Pregnancy; Testis; Toll-Like Receptors

2009
The regulation and functions of activin and follistatin in inflammation and immunity.
    Vitamins and hormones, 2011, Volume: 85

    Topics: Activins; Animals; Follistatin; Gene Expression Regulation; Humans; Immune System; Inflammation

2011
Activin-A: a novel critical regulator of allergic asthma.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2011, Volume: 41, Issue:11

    Topics: Activins; Airway Remodeling; Animals; Asthma; Cytokines; Humans; Inflammation; Signal Transduction; Transforming Growth Factor beta

2011
Regulation of activin and inhibin in the adult testis and the evidence for functional roles in spermatogenesis and immunoregulation.
    Molecular and cellular endocrinology, 2012, Aug-15, Volume: 359, Issue:1-2

    Topics: Activins; Animals; Humans; Immunomodulation; Inflammation; Inhibins; Male; Signal Transduction; Spermatogenesis; Testis

2012
The roles of activin A and its binding protein, follistatin, in inflammation and tissue repair.
    Molecular and cellular endocrinology, 2012, Aug-15, Volume: 359, Issue:1-2

    Topics: Activins; Animals; Fibrosis; Follistatin; Humans; Immunomodulation; Inflammation; Lymphocytes; TGF-beta Superfamily Proteins; Wound Healing

2012
Activin, neutrophils, and inflammation: just coincidence?
    Seminars in immunopathology, 2013, Volume: 35, Issue:4

    Topics: Activins; Adaptive Immunity; Animals; Gene Expression Regulation; Homeostasis; Humans; Immunity, Innate; Inflammation; Mice; Neutrophils

2013
The roles of activin in cytoprotection and tissue repair.
    Annals of the New York Academy of Sciences, 2003, Volume: 995

    Topics: Activins; Animals; Cytoprotection; Follistatin; Inflammation; Keratinocytes; Mice; Morphogenesis; Nerve Growth Factors; Skin; Skin Physiological Phenomena; Wound Healing

2003
Activin A and follistatin in systemic inflammation.
    Molecular and cellular endocrinology, 2004, Oct-15, Volume: 225, Issue:1-2

    Topics: Activins; Animals; Cytokines; Follistatin; Humans; Immunity, Cellular; Inflammation; Inhibin-beta Subunits

2004
Activins, inhibins and follistatins in the large domestic species.
    Domestic animal endocrinology, 2005, Volume: 28, Issue:1

    Topics: Activins; Animals; Animals, Domestic; Feedback, Physiological; Female; Follistatin; Inflammation; Inhibins; Male; Ovary; Pituitary Gland; Pregnancy; Testis; Uterus

2005
Roles of activin in tissue repair, fibrosis, and inflammatory disease.
    Cytokine & growth factor reviews, 2006, Volume: 17, Issue:3

    Topics: Activins; Animals; Cicatrix; Cytokines; Fibrosis; Humans; Inflammation; Wound Healing

2006
Production of activin A and its roles in inflammation and hematopoiesis.
    Cytokines, cellular & molecular therapy, 1997, Volume: 3, Issue:3

    Topics: Activins; Animals; Bone Marrow; Cytokines; Gene Expression Regulation; Glucocorticoids; Hematopoiesis; Humans; Inflammation; Inhibins; Interleukin-6; Monocytes; Tretinoin

1997
A novel role of activin in inflammation and repair.
    The Journal of endocrinology, 1999, Volume: 161, Issue:2

    Topics: Activins; Animals; Brain Injuries; Growth Substances; Humans; Inflammation; Inhibins; Rats; Skin; Wound Healing

1999
Activin A and follistatin: their role in the acute phase reaction and inflammation.
    The Journal of endocrinology, 1999, Volume: 161, Issue:2

    Topics: Activins; Acute-Phase Reaction; Follistatin; Glycoproteins; Growth Substances; Humans; Inflammation; Inhibins

1999
Evidence for activin A and follistatin involvement in the systemic inflammatory response.
    Molecular and cellular endocrinology, 2001, Jun-30, Volume: 180, Issue:1-2

    Topics: Activins; Animals; Drug Interactions; Follistatin; Humans; Inflammation; Inhibin-beta Subunits; Signal Transduction

2001

Trials

1 trial(s) available for activins and Inflammation

ArticleYear
Circulating conventional and plasmacytoid dendritic cell subsets display distinct kinetics during in vivo repeated allergen skin challenges in atopic subjects.
    BioMed research international, 2014, Volume: 2014

    Topics: Activins; Adolescent; Adult; Allergens; Dendritic Cells; Dermatitis, Atopic; Female; Gene Expression Regulation; Humans; Inflammation; Male; Middle Aged; Plasma Cells; Receptors, CCR10; Receptors, CCR4; Skin; Skin Tests

2014

Other Studies

50 other study(ies) available for activins and Inflammation

ArticleYear
Deletion of activin A in mesenchymal but not myeloid cells ameliorates disease severity in experimental arthritis.
    Annals of the rheumatic diseases, 2022, Volume: 81, Issue:8

    Topics: Activins; Animals; Arthritis, Experimental; Fibroblasts; Inflammation; Mice; Severity of Illness Index; Synovial Membrane; Synoviocytes

2022
Recapitulation of pro-inflammatory signature of monocytes with ACVR1A mutation using FOP patient-derived iPSCs.
    Orphanet journal of rare diseases, 2022, 09-21, Volume: 17, Issue:1

    Topics: Activin Receptors, Type I; Activins; Animals; Doxycycline; Humans; Inflammation; Lipopolysaccharides; Mice; Monocytes; Mutation; Myositis Ossificans; Ossification, Heterotopic; Signal Transduction; Transforming Growth Factor beta

2022
Effects of hyaluronic acid on differentiation of human amniotic epithelial cells and cell-replacement therapy in type 1 diabetic mice.
    Experimental cell research, 2019, 11-15, Volume: 384, Issue:2

    Topics: Activins; Amnion; Animals; Cell Culture Techniques; Cell Differentiation; Cell- and Tissue-Based Therapy; Cells, Cultured; Diabetes Mellitus, Experimental; Disease Models, Animal; Embryonic Stem Cells; Endoderm; Epithelial Cells; Humans; Hyaluronic Acid; Inflammation; Insulin; Insulin-Secreting Cells; Male; Mice; Pancreas

2019
Urinary Activin A is a novel biomarker reflecting renal inflammation and tubular damage in ANCA-associated vasculitis.
    PloS one, 2019, Volume: 14, Issue:10

    Topics: Activins; Aged; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Biomarkers; Biopsy; Female; Humans; Inflammation; Inhibin-beta Subunits; Kidney Tubules; Male; RNA, Messenger

2019
Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-α-dependent pathways.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 06-02, Volume: 117, Issue:22

    Topics: 5'-Nucleotidase; Activins; Animals; Antigens, CD; Apyrase; Cell Differentiation; Encephalomyelitis, Autoimmune, Experimental; GPI-Linked Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Th17 Cells

2020
Time to activin on pathogenic T cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 06-09, Volume: 117, Issue:23

    Topics: Activins; Autoimmune Diseases; Inflammation; T-Lymphocytes; Virulence

2020
CD28 is expressed by macrophages with anti-inflammatory potential and limits their T-cell activating capacity.
    European journal of immunology, 2021, Volume: 51, Issue:4

    Topics: Activins; Animals; Arthritis, Rheumatoid; CD28 Antigens; Cells, Cultured; Gene Expression; Gene Expression Profiling; Humans; Inflammation; Lymphocyte Activation; Macrophages; MafB Transcription Factor; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction; T-Lymphocytes

2021
The effects of activin A on the migration of human breast cancer cells and neutrophils and their migratory interaction.
    Experimental cell research, 2017, 08-01, Volume: 357, Issue:1

    Topics: Activins; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Humans; Inflammation; Neutrophils; Transforming Growth Factor beta

2017
The effects of pessimism on cell-mediated immunity in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2018, Jan-03, Volume: 80, Issue:Pt C

    Topics: Activins; Animals; Avoidance Learning; Biomarkers; Cell Proliferation; Discrimination, Psychological; Immunity, Cellular; Inflammation; Interferon-gamma; Interleukin-1beta; Interleukin-4; L-Selectin; Male; Optimism; Organ Size; Pessimism; Rats; Spleen; T-Lymphocytes; Thymus Gland; Uncertainty

2018
Stem cells from human apical papilla decrease neuro-inflammation and stimulate oligodendrocyte progenitor differentiation via activin-A secretion.
    Cellular and molecular life sciences : CMLS, 2018, Volume: 75, Issue:15

    Topics: Activins; Adult; Animals; Cell Differentiation; Cell Line; Demyelinating Diseases; Dental Papilla; Humans; Inflammation; Mice; Neurons; Oligodendrocyte Precursor Cells; Oligodendroglia; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries; Stem Cells; Tumor Necrosis Factor-alpha

2018
The Activin A-Peroxisome Proliferator-Activated Receptor Gamma Axis Contributes to the Transcriptome of GM-CSF-Conditioned Human Macrophages.
    Frontiers in immunology, 2018, Volume: 9

    Topics: Activins; Animals; Cell Differentiation; Cell Line; Culture Media, Conditioned; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; HEK293 Cells; Humans; Inflammation; Macrophages, Alveolar; Mice; Mice, Inbred C57BL; PPAR gamma; RNA Interference; RNA, Small Interfering

2018
IVIg Promote Cross-Tolerance against Inflammatory Stimuli In Vitro and In Vivo.
    Journal of immunology (Baltimore, Md. : 1950), 2018, 07-01, Volume: 201, Issue:1

    Topics: Activins; Animals; Anti-Inflammatory Agents; Cells, Cultured; Chemokine CCL2; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immune Tolerance; Immunoglobulins, Intravenous; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; Mice; Monocytes; STAT5 Transcription Factor

2018
Activin-A exerts a crucial anti-inflammatory role in neonatal infections.
    Pediatric research, 2013, Volume: 74, Issue:6

    Topics: Activins; Case-Control Studies; Chemokines; Cytokines; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Infections; Inflammation; Monocytes

2013
Activin A: a potential therapeutic target for characterizing and stopping joint pain early in rheumatoid arthritis patients.
    Inflammation, 2014, Volume: 37, Issue:1

    Topics: Activins; Animals; Arthralgia; Arthritis, Rheumatoid; Biomarkers; Humans; Inflammation; Inflammation Mediators; Macrophage Activation; Macrophages; Mice; Rats; Synovial Fluid; Synovial Membrane; Synovitis

2014
Role of activin-A in cigarette smoke-induced inflammation and COPD.
    The European respiratory journal, 2014, Volume: 43, Issue:4

    Topics: Activins; Animals; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Follistatin; Humans; Immunohistochemistry; Inflammation; Lung; Mice; Mice, Inbred C57BL; Pulmonary Disease, Chronic Obstructive; Real-Time Polymerase Chain Reaction; RNA, Messenger; Smoke; Smoking

2014
Activin-A: active in inflammation in COPD.
    The European respiratory journal, 2014, Volume: 43, Issue:4

    Topics: Activins; Animals; Humans; Inflammation; Pulmonary Disease, Chronic Obstructive; Smoking

2014
Macrophages from the synovium of active rheumatoid arthritis exhibit an activin A-dependent pro-inflammatory profile.
    The Journal of pathology, 2015, Volume: 235, Issue:3

    Topics: Activins; Adult; Aged; Arthritis, Rheumatoid; Cells, Cultured; Female; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; In Vitro Techniques; Inflammation; Lipopolysaccharide Receptors; Macrophages; Male; Matrix Metalloproteinase 12; Middle Aged; Phenotype; Receptors, CCR2; Signal Transduction; Smad Proteins; Synovial Membrane; Transcriptome

2015
Differential Expression and Release of Activin A and Follistatin in Chronic Rhinosinusitis with and without Nasal Polyps.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Activins; Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Extracellular Matrix Proteins; Female; Follistatin; Humans; Inflammation; Interferon-gamma; Interleukin-5; Male; Middle Aged; Nasal Polyps; Sinusitis; Transforming Growth Factor beta; Young Adult

2015
Chronic Noise Exposure Acts Cumulatively to Exacerbate Alzheimer's Disease-Like Amyloid-β Pathology and Neuroinflammation in the Rat Hippocampus.
    Scientific reports, 2015, Aug-07, Volume: 5

    Topics: Activins; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Calcium-Binding Proteins; Hippocampus; Inflammation; Male; Microfilament Proteins; Neurons; Noise; Platelet-Derived Growth Factor; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Tumor Necrosis Factor-alpha; Up-Regulation

2015
Possible involvement of inflammatory/reparative processes in the development of uterine fibroids.
    Cell and tissue research, 2016, Volume: 364, Issue:2

    Topics: Actins; Activins; Antigens, CD34; Collagen; Desmin; Female; Fibroblasts; Humans; Immunohistochemistry; Inflammation; Inflammation Mediators; Leiomyoma, Epithelioid; Macrophages; Mast Cells; Myometrium; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha; Uterine Neoplasms; Uterus

2016
Atypical Activin A and IL-10 Production Impairs Human CD16+ Monocyte Differentiation into Anti-Inflammatory Macrophages.
    Journal of immunology (Baltimore, Md. : 1950), 2016, Feb-01, Volume: 196, Issue:3

    Topics: Activins; Blotting, Western; Cell Differentiation; Cell Separation; Flow Cytometry; Fluorescent Antibody Technique; Humans; Inflammation; Interleukin-10; Macrophages; Monocytes; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Receptors, IgG

2016
Activin B Induces Noncanonical SMAD1/5/8 Signaling via BMP Type I Receptors in Hepatocytes: Evidence for a Role in Hepcidin Induction by Inflammation in Male Mice.
    Endocrinology, 2016, Volume: 157, Issue:3

    Topics: Activins; Animals; Bone Morphogenetic Protein Receptors, Type I; Cell Line, Tumor; Hepatocytes; Hepcidins; Humans; Immunoblotting; Inflammation; Male; Mice; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad1 Protein; Smad5 Protein; Smad8 Protein; Surface Plasmon Resonance

2016
Imbalance of Amniotic Fluid Activin-A and Follistatin in Intraamniotic Infection, Inflammation, and Preterm Birth.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:7

    Topics: Activins; Adult; Amniotic Fluid; Chorioamnionitis; Female; Fetal Membranes, Premature Rupture; Follistatin; Humans; Infant, Newborn; Inflammation; Obstetric Labor, Premature; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Premature Birth

2016
Activin inhibition limits early innate immune response in rat kidney allografts-a pilot study.
    Transplant international : official journal of the European Society for Organ Transplantation, 2017, Volume: 30, Issue:1

    Topics: Activins; Allografts; Animals; Cytokines; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Humans; Immunity, Innate; Inflammation; Kidney; Kidney Transplantation; Male; Pilot Projects; Rats; Rats, Wistar; Renal Insufficiency; Reperfusion Injury; Signal Transduction; Time Factors; Transforming Growth Factor beta; Transplantation, Homologous

2017
Activin A and follistatin in patients with asthma. Does severity make the difference?
    Respirology (Carlton, Vic.), 2017, Volume: 22, Issue:3

    Topics: Activins; Adult; Aged; Airway Remodeling; Asthma; Basement Membrane; Bronchi; Bronchoalveolar Lavage Fluid; Case-Control Studies; Cytokines; Eosinophils; Female; Follistatin; Humans; Inflammation; Male; Middle Aged; Severity of Illness Index; Sputum; Transforming Growth Factor beta1

2017
Hepcidin upregulation by inflammation is independent of Smad1/5/8 signaling by activin B.
    Blood, 2017, 01-26, Volume: 129, Issue:4

    Topics: Activins; Animals; Bacterial Infections; Bone Morphogenetic Protein 6; Endotoxemia; Escherichia coli Infections; Gene Expression Regulation; Hepcidins; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Protein Processing, Post-Translational; Pyrazoles; Pyrimidines; RNA, Messenger; Signal Transduction; Smad Proteins; Turpentine; Up-Regulation

2017
Regulation of hepcidin expression by inflammation-induced activin B.
    Scientific reports, 2016, 12-06, Volume: 6

    Topics: Activin Receptors, Type II; Activins; Animals; Bone Morphogenetic Protein Receptors, Type I; Cattle; Chemical and Drug Induced Liver Injury; Gene Expression Regulation; Hepatocytes; Hepcidins; Humans; Inflammation; Lipopolysaccharides; Male; Rats; Rats, Sprague-Dawley; Smad Proteins

2016
Activin A Inhibits MPTP and LPS-Induced Increases in Inflammatory Cell Populations and Loss of Dopamine Neurons in the Mouse Midbrain In Vivo.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Activins; Animals; Cell Survival; Disease Models, Animal; Dopaminergic Neurons; Inflammation; Lipopolysaccharides; Male; Mesencephalon; Mice; Mice, Inbred C57BL; MPTP Poisoning

2017
Testicular activin and follistatin levels are elevated during the course of experimental autoimmune epididymo-orchitis in mice.
    Scientific reports, 2017, 02-13, Volume: 7

    Topics: Actins; Activins; Animals; Antigens, CD; Autoimmune Diseases; Cell Count; Cytokines; Epididymitis; Fibrosis; Follistatin; Histocompatibility Antigens Class II; Inflammation; Macrophages; Male; Mice, Inbred C57BL; Orchitis; Organ Size; RNA, Messenger; T-Lymphocytes; Testis; Up-Regulation

2017
Activin A is essential for neurogenesis following neurodegeneration.
    Stem cells (Dayton, Ohio), 2009, Volume: 27, Issue:6

    Topics: Activins; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique; Gliosis; Hippocampus; Inflammation; Kainic Acid; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Neurogenesis

2009
Anti-inflammatory therapy in an ovine model of fetal hypoxia induced by single umbilical artery ligation.
    Reproduction, fertility, and development, 2011, Volume: 23, Issue:2

    Topics: Activins; Amniotic Fluid; Animals; Anti-Inflammatory Agents; Dinoprostone; Disease Models, Animal; Female; Fetal Blood; Fetal Hypoxia; Hydrogen-Ion Concentration; Inflammation; Interleukin-6; Ligation; Oxygen; Pregnancy; Sheep; Sulfasalazine; Tumor Necrosis Factor-alpha; Umbilical Arteries

2011
Incomplete activation of peripheral blood dendritic cells during healthy human pregnancy.
    Clinical and experimental immunology, 2011, Volume: 164, Issue:2

    Topics: Activins; Adult; Antigen Presentation; Cells, Cultured; Cytokines; Dendritic Cells; Female; Flow Cytometry; HLA-DR Antigens; Humans; Immune Tolerance; Inflammation; Leukocytes, Mononuclear; Lymphocyte Culture Test, Mixed; Maternal-Fetal Exchange; Pregnancy; Pregnancy Trimester, Third; Recombinant Proteins; Up-Regulation; Young Adult

2011
Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers.
    Blood, 2011, May-12, Volume: 117, Issue:19

    Topics: Activins; Animals; Biomarkers; Blotting, Western; Cell Differentiation; Cell Line; Cell Separation; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression; Gene Expression Profiling; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Inflammation; Macrophage Colony-Stimulating Factor; Macrophages; Mice; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad Proteins; Transfection

2011
Tumour necrosis factor-α stimulates human neutrophils to release preformed activin A.
    Immunology and cell biology, 2011, Volume: 89, Issue:8

    Topics: Activins; Apoptosis; Enzyme-Linked Immunosorbent Assay; Humans; Imidazoles; Inflammation; Inflammation Mediators; Leukocytes, Mononuclear; Lipopolysaccharides; MAP Kinase Signaling System; Neutrophils; Pyridines; RNA, Messenger; Tumor Necrosis Factor-alpha

2011
Activin A levels are associated with abnormal glucose regulation in patients with myocardial infarction: potential counteracting effects of activin A on inflammation.
    Diabetes, 2011, Volume: 60, Issue:5

    Topics: Activins; Aged; Blood Glucose; Female; Glucose Tolerance Test; Humans; Immunoenzyme Techniques; Inflammation; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Reverse Transcriptase Polymerase Chain Reaction

2011
Activin A and cardiovascular disease in type 2 diabetes mellitus.
    Diabetes & vascular disease research, 2012, Volume: 9, Issue:3

    Topics: Activins; Adult; Aged; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Follistatin; Humans; Inflammation; Linear Models; Male; Middle Aged

2012
Activin C expressed in nociceptive afferent neurons is required for suppressing inflammatory pain.
    Brain : a journal of neurology, 2012, Volume: 135, Issue:Pt 2

    Topics: Activins; Animals; Behavior, Animal; Cell Count; Chronic Pain; Extracellular Signal-Regulated MAP Kinases; Ganglia, Spinal; Hyperalgesia; Inflammation; Inhibin-beta Subunits; Nociceptors; Phosphorylation; Rats; Rats, Sprague-Dawley

2012
Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling.
    Blood, 2012, Jul-12, Volume: 120, Issue:2

    Topics: Activins; Animals; Antimicrobial Cationic Peptides; Bone Morphogenetic Protein 6; Bone Morphogenetic Proteins; Hep G2 Cells; Hepatocytes; Hepcidins; Humans; Inflammation; Interleukin-6; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; RNA, Messenger; Signal Transduction; Smad Proteins; Up-Regulation

2012
The prolyl hydroxylase PHD3 identifies proinflammatory macrophages and its expression is regulated by activin A.
    Journal of immunology (Baltimore, Md. : 1950), 2012, Aug-15, Volume: 189, Issue:4

    Topics: Activins; Blotting, Western; Dioxygenases; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor-Proline Dioxygenases; Immunohistochemistry; Inflammation; Macrophages; Microscopy, Confocal; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction

2012
Regulation of activin A release from murine bone marrow-derived neutrophil precursors by tumour necrosis factor-α and insulin.
    Cytokine, 2013, Volume: 61, Issue:1

    Topics: Activins; Animals; Bone Marrow Cells; Cells, Cultured; Glucose; Inflammation; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Tumor Necrosis Factor-alpha

2013
Activin, a grape seed-derived proanthocyanidin extract, reduces plasma levels of oxidative stress and adhesion molecules (ICAM-1, VCAM-1 and E-selectin) in systemic sclerosis.
    Free radical research, 2002, Volume: 36, Issue:8

    Topics: Activins; Anthocyanins; Cell Adhesion; E-Selectin; Humans; Inflammation; Intercellular Adhesion Molecule-1; Malondialdehyde; Models, Chemical; Oxidative Stress; Pilot Projects; Plant Extracts; Proanthocyanidins; Scleroderma, Systemic; Seeds; Vascular Cell Adhesion Molecule-1; Vitis

2002
Potential anti-inflammatory role of activin A in acute coronary syndromes.
    Journal of the American College of Cardiology, 2004, Jul-21, Volume: 44, Issue:2

    Topics: Activins; Angina, Unstable; Angioplasty, Balloon, Coronary; Cells, Cultured; Cytokines; DNA-Binding Proteins; Female; Follistatin; Gene Expression; Humans; Inflammation; Inflammation Mediators; Inhibin-beta Subunits; Leukocytes, Mononuclear; Male; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Smad Proteins; Trans-Activators

2004
Glomerular activin A overexpression is linked to fibrosis in anti-Thy1 glomerulonephritis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2005, Volume: 20, Issue:2

    Topics: Activins; Animals; Cells, Cultured; Disease Models, Animal; Enalapril; Fibroblast Growth Factor 2; Gene Expression Regulation; Glomerular Mesangium; Inflammation; Inhibin-beta Subunits; Interleukin-1; Male; Rats; Rats, Sprague-Dawley; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1

2005
Activin induces tactile allodynia and increases calcitonin gene-related peptide after peripheral inflammation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Oct-05, Volume: 25, Issue:40

    Topics: Activins; Animals; Ankle; Calcitonin Gene-Related Peptide; Female; Freund's Adjuvant; Ganglia, Spinal; Gene Expression Regulation; Hyperesthesia; Immunohistochemistry; Inflammation; Inhibin-beta Subunits; Nerve Growth Factor; Neurons, Afferent; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Time Factors; Touch

2005
Activin acts with nerve growth factor to regulate calcitonin gene-related peptide mRNA in sensory neurons.
    Neuroscience, 2007, Dec-12, Volume: 150, Issue:3

    Topics: Activins; Animals; Calcitonin Gene-Related Peptide; Cells, Cultured; Drug Synergism; Ganglia, Spinal; Gene Expression; Hyperalgesia; Inflammation; Ligands; Nerve Growth Factor; Neurons, Afferent; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction

2007
Production and function of activin A in human dendritic cells.
    European cytokine network, 2008, Volume: 19, Issue:1

    Topics: Activins; Cytokines; Dendritic Cells; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Follistatin; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Langerhans Cells; Lipopolysaccharides; Models, Biological; Monocytes; Reverse Transcriptase Polymerase Chain Reaction

2008
Inflammatory potency of activin A. Effect on prostanoid and nitric oxide formation.
    Advances in experimental medicine and biology, 1997, Volume: 407

    Topics: Activins; Animals; Bone Marrow Cells; Cell Differentiation; Cinnamates; Cyclooxygenase 2; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Genistein; Inflammation; Inhibins; Interleukin-2; Isoenzymes; Lipopolysaccharides; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Necrosis Factor-alpha; Tyrphostins

1997
Activin A regulates growth and acute phase proteins in the human liver cell line, HepG2.
    Molecular and cellular endocrinology, 1999, Feb-25, Volume: 148, Issue:1-2

    Topics: Activins; Acute-Phase Proteins; Carcinoma, Hepatocellular; Cell Division; Dose-Response Relationship, Drug; Follistatin; Glycoproteins; Growth Substances; Haptoglobins; Humans; Inflammation; Inhibins; Interleukin-1; Interleukin-6; Kinetics; Liver Neoplasms; Orosomucoid; Recombinant Proteins; Tumor Cells, Cultured

1999
Activin A release into the circulation is an early event in systemic inflammation and precedes the release of follistatin.
    Endocrinology, 2000, Volume: 141, Issue:5

    Topics: Activins; Animals; Enzyme-Linked Immunosorbent Assay; Follistatin; Glycoproteins; Inflammation; Inhibins; Interleukin-6; Lipopolysaccharides; Sheep; Tumor Necrosis Factor-alpha

2000
New developments in the biology of inhibins, activins and follistatins.
    Trends in endocrinology and metabolism: TEM, 2001, Volume: 12, Issue:3

    Topics: Activin Receptors; Activins; Animals; Cell Division; Female; Follistatin; Glycoproteins; Humans; Inflammation; Inhibins; Neoplasms; Pituitary-Adrenal System; Pregnancy; Receptors, Growth Factor; Receptors, Peptide; Wound Healing

2001