Page last updated: 2024-10-31

activins and Edema-Proteinuria-Hypertension Gestosis

activins has been researched along with Edema-Proteinuria-Hypertension Gestosis in 64 studies

Activins: Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.

Research Excerpts

ExcerptRelevanceReference
"To analyse the predictive power of maternal serum inhibin A, activin A, human chorionic gonadotropin (hCG), unconjugated estriol (uE(3)), alpha-fetoprotein (AFP) levels and uterine artery Doppler in the second trimester of pregnancy in screening for pre-eclampsia."7.73Screening for pre-eclampsia by using maternal serum inhibin A, activin A, human chorionic gonadotropin, unconjugated estriol, and alpha-fetoprotein levels and uterine artery Doppler in the second trimester of pregnancy. ( Ay, E; Elter, K; Gokaslan, H; Kavak, ZN; Pekin, T, 2005)
"To analyse the predictive power of maternal serum inhibin A, activin A, human chorionic gonadotropin (hCG), unconjugated estriol (uE(3)), alpha-fetoprotein (AFP) levels and uterine artery Doppler in the second trimester of pregnancy in screening for pre-eclampsia."3.73Screening for pre-eclampsia by using maternal serum inhibin A, activin A, human chorionic gonadotropin, unconjugated estriol, and alpha-fetoprotein levels and uterine artery Doppler in the second trimester of pregnancy. ( Ay, E; Elter, K; Gokaslan, H; Kavak, ZN; Pekin, T, 2005)
"Preeclampsia is a major cause of maternal morbidity and mortality worldwide."2.44Novel biomarkers for predicting preeclampsia. ( Carty, DM; Delles, C; Dominiczak, AF, 2008)
"It is known that preeclampsia affects lactogenesis."1.91Preeclampsia and Its Impact on Human Milk Activin A Concentration. ( Barbagallo, I; Bertino, E; Coscia, A; Galvano, F; Gazzolo, D; Livolti, G; Peila, C; Riboldi, L; Sottemano, S; Spada, E, 2023)
"Preeclampsia is a multisystem hypertensive disorder of pregnancy that remains one of the leading causes of maternal and perinatal morbidity and mortality worldwide."1.72Activin A causes endothelial dysfunction of mouse aorta and human aortic cells. ( Barber, C; Hannan, NJ; Marshall, SA; Wallace, EM; Yap, Y, 2022)
"Clinical management of preeclampsia has remained unchanged for almost 5 decades."1.42Activin and NADPH-oxidase in preeclampsia: insights from in vitro and murine studies. ( Acharya, R; Delpachitra, P; Drummond, GR; Hobson, S; Lim, R; Sobey, CG; Wallace, EM, 2015)
"The pregnancy-specific disorder preeclampsia is a major cause of maternal mortality and morbidity."1.38High levels of activin A detected in preeclamptic placenta induce trophoblast cell apoptosis by promoting nodal signaling. ( Bai, Y; Cao, B; Cui, N; Fu, G; Li, D; Li, J; Li, YX; Liao, QP; Liu, M; Peng, C; Wang, H; Wang, YL; Yang, HX; Ye, G; Yu, L, 2012)
"In the women with preeclampsia, but not in those with a normal pregnancy, circulating levels of 8-isoprostane and activin A were significantly and positively correlated (r(2) = 0."1.34Oxidative stress increases placental and endothelial cell activin A secretion. ( Mandang, S; Manuelpillai, U; Wallace, EM, 2007)
"The best cut-off values for predicting preeclampsia of placental growth factor, activin A and fibronectin based on ROC curve analysis were 90 pg/ml, 14 ng/ml and 370 mg/l respectively."1.33Prediction of preeclampsia with maternal mid-trimester placental growth factor, activin A, fibronectin and uterine artery Doppler velocimetry. ( Kuseyrioglu, B; Madazli, R; Ocak, V; Uludag, S; Uzun, H, 2005)
"Preeclampsia has been shown to be associated with an increased number of fetal and maternal erythroblasts in the maternal circulation, suggesting that preeclampsia involves increased leakage of fetal cells across the placental barrier, as well as increased erythropoiesis."1.33Examination of maternal plasma erythropoietin and activin A concentrations with regard to circulatory erythroblast levels in normal and preeclamptic pregnancies. ( Hahn, S; Holzgreve, W; Ladewig, A; Troeger, C; Zhong, XY, 2006)
"Those with chronic hypertension have lower serum but not urine free activin A levels, compared with severe pre-eclampsia and mild pre-eclampsia."1.33Serum and urine inhibin A but not free activin A are endocrine biomarkers of severe pre-eclampsia. ( Buhimschi, CS; Buhimschi, IA; Copel, JA; Funai, EF; Hamar, BD; Magloire, LK; Pettker, CM; Sfakianaki, AK, 2006)
"Activin A is not a useful predictor of preeclampsia in this setting."1.32Maternal serum activin A is not elevated before preeclampsia in women who are at high risk. ( Blackburn, CA; Keelan, JA; North, RA; Taylor, RS, 2003)
"Nineteen women with preeclampsia symptoms were matched with 19 normal pregnant controls for gestational age, maternal age, and parity."1.32Women with preeclampsia have increased serum levels of pregnancy-associated plasma protein A (PAPP-A), inhibin A, activin A and soluble E-selectin. ( Bersinger, NA; Groome, NP; Muttukrishna, S; Redman, CW; Smárason, AK, 2003)
"Activin A is raised in preeclampsia, suggesting a possible involvement in its pathophysiology."1.32Endothelial cells and peripheral blood mononuclear cells are a potential source of extraplacental activin a in preeclampsia. ( Groome, NP; Muttukrishna, S; Redman, CW; Sargent, IL; Tannetta, DS, 2003)
"Twenty women with preeclampsia were enrolled in this study."1.32[Study on the relationship between activin A, follistatin and preeclampsia]. ( Li, H; Liu, ZH; Shang, T; Tang, S; Wang, YL; Zhao, L, 2003)
"Twelve patients with preeclampsia were identified and matched with 24 controls."1.31Serum levels of activin A and inhibin A and the subsequent development of preeclampsia. ( Grobman, WA; Wang, EY, 2000)
"Serum samples of 20 women with preeclampsia (study group) and 20 normotensive pregnant women, matched for maternal and gestational age and parity, were assayed for inhibin A, inhibin B and activin A by specific enzyme-linked immunosorbent assay."1.31Serum levels of inhibin B, unlike inhibin A and activin A, are not altered in women with preeclampsia. ( Eshed-Englender, T; Frenkel, J; Geva, E; Kupferminc, MJ; Sherman, D; Yair, D, 2001)
"In contrast to women with preeclampsia, normotensive women with SGA pregnancies do not have markedly elevated circulating levels of activin A and inhibin A."1.31Serum activin A, inhibin A, and follistatin concentrations in preeclampsia or small for gestational age pregnancies. ( Groome, NP; Keelan, JA; Mitchell, MD; North, RA; Schellenberg, JC; Taylor, R, 2002)
"Activin A levels were higher in the preeclampsia group (median 31."1.30Comparison of maternal serum total activin A and inhibin A in normal, preeclamptic, and nonproteinuric gestationally hypertensive pregnancies. ( Canick, JA; Hogan, J; Lambert-Messerlian, GM; Silver, HM; Star, JA, 1999)

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (7.81)18.2507
2000's38 (59.38)29.6817
2010's17 (26.56)24.3611
2020's4 (6.25)2.80

Authors

AuthorsStudies
Wong, GP1
Andres, F1
Walker, SP1
MacDonald, TM1
Cannon, P1
Nguyen, TV1
Keenan, E1
Hannan, NJ2
Tong, S2
Kaitu'u-Lino, TJ1
Barber, C1
Yap, Y1
Wallace, EM11
Marshall, SA2
Barrero, JA1
Villamil-Camargo, LM1
Imaz, JN1
Arciniegas-Villa, K1
Rubio-Romero, JA1
Coscia, A1
Riboldi, L1
Spada, E1
Bertino, E1
Sottemano, S1
Barbagallo, I1
Livolti, G1
Galvano, F1
Gazzolo, D1
Peila, C1
Hobson, SR2
Lim, R5
Mockler, JC2
Gurusinghe, S3
Cox, AG1
Rahman, R2
Chan, ST2
Muljadi, R1
Singh, H1
Leaw, B2
Murthi, P2
Acharya, R3
Delpachitra, P1
Hobson, S1
Sobey, CG1
Drummond, GR1
Gangooly, S1
Muttukrishna, S8
Jauniaux, E1
Williamson, RD1
O'Keeffe, GW1
Kenny, LC1
Thulluru, HK1
Michel, OJ1
Oudejans, CB1
van Dijk, M1
Adhikari, S1
Ciayadi, R1
Potdar, M1
Kelso, GF1
Hearn, MT1
Zhu, XL1
Wang, J1
Jiang, RZ1
Teng, YC1
Yong, HE1
Wong, MH1
Kalionis, B1
Cartwright, JE1
Brennecke, SP1
Keogh, RJ1
Wijayarathna, R1
de Kretser, DM2
Mockler, J1
Xu, YT1
Shen, MH1
Jin, AY1
Li, H3
Zhu, R1
Carty, DM1
Delles, C1
Dominiczak, AF1
Spencer, K3
Cowans, NJ1
Nicolaides, KH5
Reddy, A1
Suri, S1
Sargent, IL2
Redman, CW6
Akolekar, R1
Etchegaray, A1
Zhou, Y1
Maiz, N1
Yu, J1
Shixia, CZ1
Wu, Y1
Duan, T1
Huang, F1
Shelling, AN1
Yu, L1
Li, D1
Liao, QP1
Yang, HX1
Cao, B1
Fu, G1
Ye, G1
Bai, Y1
Wang, H1
Cui, N1
Liu, M1
Li, YX1
Li, J1
Peng, C1
Wang, YL2
Lai, J1
Pinas, A1
Syngelaki, A1
Poon, LC1
Blumenstein, M1
Mitchell, MD2
Groome, NP7
Keelan, JA3
Manuelpillai, U3
Schneider-Kolsky, M2
Thirunavukarasu, P1
Dole, A2
Waldron, K1
Davidson, EJ1
Riley, SC1
Roberts, SA1
Shearing, CH1
Martin, CW1
Florio, P3
Ciarmela, P1
Luisi, S2
Palumbo, MA1
Lambert-Messerlian, G1
Severi, FM2
Petraglia, F4
Reis, FM2
Pezzani, I1
Schneider-Kolsky, ME1
Edwards, A1
Baker, L1
Jenkin, G1
Blackburn, CA1
Taylor, RS2
North, RA3
Bersinger, NA1
Smárason, AK1
Casagrandi, D1
Bearfield, C1
Geary, J1
Hanisch, CG1
Pfeiffer, KA1
Schlebusch, H1
Schmolling, J1
Tannetta, DS1
Zhao, L1
Shang, T1
Tang, S1
Liu, ZH1
Seufert, R1
Neubert, S1
Tanner, B1
Schaffrath, M1
Pollow, K1
Kölbl, H1
Ong, CY1
Liao, AW1
Munim, S1
Rohra, DK1
Qidwai, N1
Madazli, R1
Kuseyrioglu, B1
Uzun, H1
Uludag, S1
Ocak, V1
Ay, E1
Kavak, ZN1
Elter, K1
Gokaslan, H1
Pekin, T1
Troeger, C1
Holzgreve, W2
Ladewig, A1
Zhong, XY2
Hahn, S2
Yu, CK1
Savvidou, M1
Papageorghiou, AT1
Ekbom, P1
Damm, P1
Andersson, AM1
Skakkebaek, NE1
Feldt-Rasmussen, U1
Mathiesen, ER1
Hyett, J1
Paine, M1
Moodley, J1
Groome, N2
Rodeck, C1
Arai, K1
Taya, K1
Hamar, BD1
Buhimschi, IA1
Sfakianaki, AK1
Pettker, CM1
Magloire, LK1
Funai, EF1
Copel, JA1
Buhimschi, CS1
Diesch, CH1
Mandang, S1
Banzola, I1
Farina, A1
Concu, M1
Sekizawa, A1
Purwosunu, Y1
Strada, I1
Arcelli, D1
Simonazzi, G1
Caramelli, E1
Rizzo, N1
Aguzzoli, L1
Gallinelli, A1
Zonca, M1
Benedetto, C2
Woodruff, K1
Lindheimer, MD1
Woodruff, TK1
Knight, PG1
Ledger, WL2
Silver, HM1
Lambert-Messerlian, GM1
Star, JA1
Hogan, J1
Canick, JA1
Laivuori, H1
Kaaja, R1
Turpeinen, U1
Stenman, UH1
Ylikorkala, O1
D'Antona, D1
Evans, LW1
Morris, J1
Schellenberg, JC2
Asselin, J1
Ledger, W1
Grobman, WA1
Wang, EY1
Yair, D1
Eshed-Englender, T1
Kupferminc, MJ1
Geva, E1
Frenkel, J1
Sherman, D1
Taylor, R1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Is a History of Pre-eclampsia Before Systemic Sclerosis Onset a Risk Factor for Vascular Phenotype in Women With Systemic Sclerosis?[NCT04363021]378 participants (Actual)Observational2020-07-06Completed
Diagnostic Value of Calponin 2 in Identifying Tubal Pregnancies[NCT05591599]407 participants (Anticipated)Observational2022-12-05Recruiting
Screening for Placental Insufficiency by a Combination of Second Trimester Uterine Artery Doppler and Maternal Serum Leptin and Lipids[NCT00465634]235 participants (Actual)Observational2003-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for activins and Edema-Proteinuria-Hypertension Gestosis

ArticleYear
Maternal Serum Activin A, Inhibin A and Follistatin-Related Proteins across Preeclampsia: Insights into Their Role in Pathogenesis and Prediction.
    Journal of mother and child, 2023, Jun-01, Volume: 27, Issue:1

    Topics: Activins; Female; Follistatin; Follistatin-Related Proteins; Humans; Inhibins; Pre-Eclampsia; Pregna

2023
Activin signalling and pre-eclampsia: from genetic risk to pre-symptomatic biomarker.
    Cytokine, 2015, Volume: 71, Issue:2

    Topics: Activins; Biomarkers; Clinical Trials as Topic; Cytokines; Female; Genetic Predisposition to Disease

2015
Pulsatility index in combination with biomarkers or mean arterial pressure for the prediction of pre-eclampsia: Systematic literature review and meta-analysis.
    Annals of medicine, 2015, Volume: 47, Issue:5

    Topics: Activins; Biomarkers; Blood Pressure; Female; Galectins; Humans; Inhibins; Placenta Growth Factor; P

2015
Activins in reproductive biology and beyond.
    Human reproduction update, 2016, Volume: 22, Issue:3

    Topics: Activins; Animals; Female; Follistatin; Glycoproteins; Humans; Inhibin-beta Subunits; Inhibins; Male

2016
Novel biomarkers for predicting preeclampsia.
    Trends in cardiovascular medicine, 2008, Volume: 18, Issue:5

    Topics: Activins; Angiogenesis Inducing Agents; Antigens, CD; Apolipoproteins E; Biomarkers; Endoglin; Femal

2008
[Activin and activin receptors in related gynecologic and obstetric diseases].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2010, Volume: 35, Issue:8

    Topics: Activin Receptors; Activins; Animals; Endometrial Neoplasms; Endometriosis; Female; Humans; Ovarian

2010
Mutations in inhibin and activin genes associated with human disease.
    Molecular and cellular endocrinology, 2012, Aug-15, Volume: 359, Issue:1-2

    Topics: Activins; Animals; Endocrine Gland Neoplasms; Female; Genital Neoplasms, Male; Humans; Inhibins; Mal

2012
Biochemical screening for the prediction of preeclampsia.
    JPMA. The Journal of the Pakistan Medical Association, 2005, Volume: 55, Issue:2

    Topics: Activins; Biomarkers; Female; Humans; Inhibin-beta Subunits; Inhibins; Leptin; Pre-Eclampsia; Pregna

2005
Measurement of inhibin A and activin A in pregnancy--possible diagnostic applications.
    Molecular and cellular endocrinology, 2001, Jun-30, Volume: 180, Issue:1-2

    Topics: Activins; Down Syndrome; Female; Humans; Inhibins; Obstetric Labor, Premature; Pre-Eclampsia; Pregna

2001

Trials

1 trial available for activins and Edema-Proteinuria-Hypertension Gestosis

ArticleYear
The addition of activin A and inhibin A measurement to uterine artery Doppler velocimetry to improve the early prediction of pre-eclampsia.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2003, Volume: 21, Issue:2

    Topics: Activins; Adult; Blood Flow Velocity; Female; Humans; Inhibin-beta Subunits; Inhibins; Laser-Doppler

2003

Other Studies

54 other studies available for activins and Edema-Proteinuria-Hypertension Gestosis

ArticleYear
Circulating Activin A is elevated at 36 weeks' gestation preceding a diagnosis of preeclampsia.
    Pregnancy hypertension, 2022, Volume: 27

    Topics: Activins; Adult; Biomarkers; Case-Control Studies; Female; Humans; Placenta; Pre-Eclampsia; Pregnanc

2022
Activin A causes endothelial dysfunction of mouse aorta and human aortic cells.
    Reproduction (Cambridge, England), 2022, 02-14, Volume: 163, Issue:3

    Topics: Activins; Animals; Aorta; Endothelial Cells; Endothelium, Vascular; Female; Humans; Mice, Inbred C57

2022
Preeclampsia and Its Impact on Human Milk Activin A Concentration.
    Nutrients, 2023, Oct-09, Volume: 15, Issue:19

    Topics: Activins; Breast Feeding; Female; Humans; Milk, Human; Pre-Eclampsia; Pregnancy

2023
Role of Activin A in the Pathogenesis of Endothelial Cell Dysfunction in Preeclampsia.
    Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1710

    Topics: Activins; Cells, Cultured; Endothelial Cells; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Femal

2018
Resveratrol mitigates trophoblast and endothelial dysfunction partly via activation of nuclear factor erythroid 2-related factor-2.
    Placenta, 2017, Volume: 60

    Topics: Activins; Antioxidants; Endothelial Cells; Female; Heme Oxygenase-1; Human Umbilical Vein Endothelia

2017
Activin and NADPH-oxidase in preeclampsia: insights from in vitro and murine studies.
    American journal of obstetrics and gynecology, 2015, Volume: 212, Issue:1

    Topics: Activins; Animals; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Female; Humans; In Vit

2015
In-vitro study of the effect of anti-hypertensive drugs on placental hormones and angiogenic proteins synthesis in pre-eclampsia.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Activins; Angiogenic Proteins; Antigens, CD; Antihypertensive Agents; Chorionic Gonadotropin; Chorio

2014
ACVR2A promoter polymorphism rs1424954 in the Activin-A signaling pathway in trophoblasts.
    Placenta, 2015, Volume: 36, Issue:4

    Topics: Activin Receptors, Type II; Activins; Alleles; Cell Line; Down-Regulation; Exons; Female; Gene Expre

2015
Inhibition of activin A signalling in a mouse model of pre-eclampsia.
    Placenta, 2015, Volume: 36, Issue:8

    Topics: Activin Receptors; Activins; Animals; Disease Models, Animal; Female; Mice; Pre-Eclampsia; Pregnancy

2015
Effects of normal and high circulating concentrations of activin A on vascular endothelial cell functions and vasoactive factor production.
    Pregnancy hypertension, 2015, Volume: 5, Issue:4

    Topics: Activin Receptors, Type II; Activins; Adult; Biomarkers; Cell Culture Techniques; Endothelium, Vascu

2015
Role of activin A in the pathogenesis of endothelial cell dysfunction in preeclampsia.
    Pregnancy hypertension, 2016, Volume: 6, Issue:2

    Topics: Activins; Adult; Biomarkers; Case-Control Studies; Endothelin-1; Female; Human Umbilical Vein Endoth

2016
Maternal circulating levels of transforming growth factor-β superfamily and its soluble receptors in hypertensive disorders of pregnancy.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2017, Volume: 137, Issue:3

    Topics: Activins; Adult; Endoglin; Female; Humans; Hypertension, Pregnancy-Induced; Inhibins; Pre-Eclampsia;

2017
Maternal serum inhibin-A and activin-A levels in the first trimester of pregnancies developing pre-eclampsia.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2008, Volume: 32, Issue:5

    Topics: Activins; Biomarkers; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Gestational A

2008
Maternal circulating levels of activin A, inhibin A, sFlt-1 and endoglin at parturition in normal pregnancy and pre-eclampsia.
    PloS one, 2009, Volume: 4, Issue:2

    Topics: Activins; Antigens, CD; Case-Control Studies; Endoglin; Female; Humans; Inhibins; Labor, Obstetric;

2009
Maternal serum activin a at 11-13 weeks of gestation in hypertensive disorders of pregnancy.
    Fetal diagnosis and therapy, 2009, Volume: 25, Issue:3

    Topics: Activins; Adult; Case-Control Studies; Female; Gestational Age; Humans; Hypertension, Pregnancy-Indu

2009
Inhibin A, activin A, placental growth factor and uterine artery Doppler pulsatility index in the prediction of pre-eclampsia.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2011, Volume: 37, Issue:5

    Topics: Activins; Adult; Biomarkers; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Humans

2011
High levels of activin A detected in preeclamptic placenta induce trophoblast cell apoptosis by promoting nodal signaling.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:8

    Topics: Activin Receptors, Type I; Activins; Adult; Amino Acid Sequence; Apoptosis; Case-Control Studies; Ce

2012
Maternal serum activin-A at 30-33 weeks in the prediction of preeclampsia.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2013, Volume: 26, Issue:8

    Topics: Activins; Biomarkers; Case-Control Studies; Female; Humans; Pre-Eclampsia; Predictive Value of Tests

2013
Hypoxia inhibits activin A production by term villous trophoblast in vitro.
    Placenta, 2002, Volume: 23, Issue:10

    Topics: Activins; Cell Hypoxia; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Female; Follistatin; Hum

2002
Effect of hypoxia on placental activin A, inhibin A and follistatin synthesis.
    Placenta, 2003, Volume: 24, Issue:1

    Topics: Activins; Adult; Cell Hypoxia; Cells, Cultured; Cobalt; Endothelial Growth Factors; Endothelium, Vas

2003
Maternal serum activin, inhibin, human chorionic gonadotrophin and alpha-fetoprotein as second trimester predictors of pre-eclampsia.
    BJOG : an international journal of obstetrics and gynaecology, 2003, Volume: 110, Issue:1

    Topics: Activins; Adolescent; Adult; alpha-Fetoproteins; Biomarkers; Case-Control Studies; Chorionic Gonadot

2003
Pre-eclampsia with fetal growth restriction: placental and serum activin A and inhibin A levels.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2002, Volume: 16, Issue:5

    Topics: Activins; Adult; Female; Fetal Growth Retardation; Humans; Inhibin-beta Subunits; Inhibins; Placenta

2002
Maternal serum activin A levels in association with intrauterine fetal growth restriction.
    BJOG : an international journal of obstetrics and gynaecology, 2003, Volume: 110, Issue:3

    Topics: Activins; Biomarkers; Cohort Studies; Enzyme-Linked Immunosorbent Assay; Female; Fetal Growth Retard

2003
Maternal serum activin A is not elevated before preeclampsia in women who are at high risk.
    American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:3

    Topics: Activins; Adult; Cohort Studies; Female; Forecasting; Humans; Hypertension; Inhibin-beta Subunits; P

2003
Women with preeclampsia have increased serum levels of pregnancy-associated plasma protein A (PAPP-A), inhibin A, activin A and soluble E-selectin.
    Hypertension in pregnancy, 2003, Volume: 22, Issue:1

    Topics: Activins; Adolescent; Adult; Biomarkers; Case-Control Studies; E-Selectin; Enzyme-Linked Immunosorbe

2003
Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia.
    Molecular human reproduction, 2003, Volume: 9, Issue:4

    Topics: Activin Receptors; Activins; Female; Follistatin; Gene Expression Regulation; Humans; Inhibins; Plac

2003
Adhesion molecules, activin and inhibin--candidates for the biochemical prediction of hypertensive diseases in pregnancy?
    Archives of gynecology and obstetrics, 2004, Volume: 270, Issue:2

    Topics: Activins; Adult; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Enzyme-Linked Im

2004
Endothelial cells and peripheral blood mononuclear cells are a potential source of extraplacental activin a in preeclampsia.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:12

    Topics: Activins; Cells, Cultured; Endothelium, Vascular; Endotoxins; Escherichia coli; Female; Follistatin;

2003
[Study on the relationship between activin A, follistatin and preeclampsia].
    Zhonghua fu chan ke za zhi, 2003, Volume: 38, Issue:11

    Topics: Activins; Adult; Female; Follistatin; Humans; Inhibin-beta Subunits; Pre-Eclampsia; Pregnancy; RNA,

2003
[Inhibins and Activin A in hypertensive Disorders of Pregnancy and HELLP-Syndrome].
    Zentralblatt fur Gynakologie, 2004, Volume: 126, Issue:3

    Topics: Activins; Female; HELLP Syndrome; Humans; Hypertension; Inhibin-beta Subunits; Inhibins; Pre-Eclamps

2004
First-trimester maternal serum activin A in pre-eclampsia and fetal growth restriction.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2004, Volume: 15, Issue:3

    Topics: Activins; Case-Control Studies; Female; Fetal Growth Retardation; Humans; Inhibin-beta Subunits; Pre

2004
Prediction of preeclampsia with maternal mid-trimester placental growth factor, activin A, fibronectin and uterine artery Doppler velocimetry.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2005, Volume: 89, Issue:3

    Topics: Activins; Adult; Biomarkers; Blood Flow Velocity; Female; Fibronectins; Humans; Inhibin-beta Subunit

2005
Screening for pre-eclampsia by using maternal serum inhibin A, activin A, human chorionic gonadotropin, unconjugated estriol, and alpha-fetoprotein levels and uterine artery Doppler in the second trimester of pregnancy.
    The Australian & New Zealand journal of obstetrics & gynaecology, 2005, Volume: 45, Issue:4

    Topics: Activins; Adult; alpha-Fetoproteins; Arteries; Blood Flow Velocity; Chorionic Gonadotropin; Estriol;

2005
Examination of maternal plasma erythropoietin and activin A concentrations with regard to circulatory erythroblast levels in normal and preeclamptic pregnancies.
    Fetal diagnosis and therapy, 2006, Volume: 21, Issue:1

    Topics: Activins; Erythroblasts; Erythropoiesis; Erythropoietin; Female; Humans; Inhibin-beta Subunits; Plac

2006
Prediction of pre-eclampsia by uterine artery Doppler ultrasonography and maternal serum pregnancy-associated plasma protein-A, free beta-human chorionic gonadotropin, activin A and inhibin A at 22 + 0 to 24 + 6 weeks' gestation.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2006, Volume: 27, Issue:6

    Topics: Activins; Arteries; Biomarkers; Chorionic Gonadotropin, beta Subunit, Human; Epidemiologic Methods;

2006
Serum levels of activin A and inhibin A are not related to the increased susceptibility to pre-eclampsia in type I diabetic pregnancies.
    Acta obstetricia et gynecologica Scandinavica, 2006, Volume: 85, Issue:2

    Topics: Activins; Adult; Analysis of Variance; Chi-Square Distribution; Disease Susceptibility; Female; Huma

2006
Uterine vein and maternal urinary levels of activin A and inhibin A in pre-eclampsia patients.
    Clinical endocrinology, 2006, Volume: 64, Issue:4

    Topics: Activins; Adult; Analysis of Variance; Case-Control Studies; Catheterization, Peripheral; Female; Fo

2006
Activin A, hypoxia and the prediction of obstetric outcomes.
    The Australian & New Zealand journal of obstetrics & gynaecology, 2006, Volume: 46, Issue:2

    Topics: Activins; Adult; Biomarkers; Case-Control Studies; Delivery, Obstetric; Female; Fetal Growth Retarda

2006
[Inhibin/activin and pregnancy].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 4

    Topics: Activins; Animals; Biomarkers; Down Syndrome; Female; Fetal Diseases; Follistatin; Hydatidiform Mole

2006
Serum and urine inhibin A but not free activin A are endocrine biomarkers of severe pre-eclampsia.
    American journal of obstetrics and gynecology, 2006, Volume: 195, Issue:6

    Topics: Activins; Adult; Biomarkers; Creatinine; Female; Humans; Hypertension; Immunoassay; Inhibins; Pre-Ec

2006
Comparison of activin A and cell-free fetal DNA levels in maternal plasma from patients at high risk for preeclampsia.
    Prenatal diagnosis, 2006, Volume: 26, Issue:13

    Topics: Activins; Adult; Arteries; DNA; Enzyme-Linked Immunosorbent Assay; Female; Fetal Blood; Fetus; Human

2006
Oxidative stress increases placental and endothelial cell activin A secretion.
    The Journal of endocrinology, 2007, Volume: 192, Issue:3

    Topics: Activins; Adult; Antioxidants; Ascorbic Acid; Case-Control Studies; Cells, Cultured; Endothelial Cel

2007
Performance of a panel of maternal serum markers in predicting preeclampsia at 11-15 weeks' gestation.
    Prenatal diagnosis, 2007, Volume: 27, Issue:11

    Topics: Activins; Adult; Biomarkers; Case-Control Studies; Female; Humans; Mothers; P-Selectin; Pre-Eclampsi

2007
Hypertension in pregnancy: changes in activin A maternal serum concentration.
    Placenta, 1995, Volume: 16, Issue:5

    Topics: Activins; Adult; Animals; Case-Control Studies; Evaluation Studies as Topic; Female; Humans; Hyperte

1995
Activin A, inhibin A, and pre-eclampsia.
    Lancet (London, England), 1997, May-03, Volume: 349, Issue:9061

    Topics: Activins; Biomarkers; Female; Humans; Inhibins; Pre-Eclampsia; Pregnancy

1997
Activin A and inhibin A as possible endocrine markers for pre-eclampsia.
    Lancet (London, England), 1997, May-03, Volume: 349, Issue:9061

    Topics: Activins; Biomarkers; Chorionic Gonadotropin; Chromatography, Liquid; Cross-Sectional Studies; Femal

1997
Comparison of maternal serum total activin A and inhibin A in normal, preeclamptic, and nonproteinuric gestationally hypertensive pregnancies.
    American journal of obstetrics and gynecology, 1999, Volume: 180, Issue:5

    Topics: Activins; Adult; Female; Gestational Age; Humans; Hypertension; Inhibins; Pre-Eclampsia; Pregnancy;

1999
Serum activin A and inhibin A elevated in pre-eclampsia: no relation to insulin sensitivity.
    British journal of obstetrics and gynaecology, 1999, Volume: 106, Issue:12

    Topics: Activins; Adult; Biomarkers; Female; Gestational Age; Humans; Inhibins; Insulin Resistance; Peptides

1999
Increased maternal serum activin A but not follistatin levels in pregnant women with hypertensive disorders.
    The Journal of endocrinology, 2000, Volume: 165, Issue:1

    Topics: Activins; Case-Control Studies; Female; Fetal Growth Retardation; Follistatin; Glycoproteins; Humans

2000
Serum inhibin A and activin A are elevated prior to the onset of pre-eclampsia.
    Human reproduction (Oxford, England), 2000, Volume: 15, Issue:7

    Topics: Activins; Adult; Case-Control Studies; Female; Gestational Age; Humans; Hypertension; Inhibins; Long

2000
Serum levels of activin A and inhibin A and the subsequent development of preeclampsia.
    Obstetrics and gynecology, 2000, Volume: 96, Issue:3

    Topics: Activins; Adolescent; Adult; Biomarkers; Female; Humans; Infant, Newborn; Inhibins; Pre-Eclampsia; P

2000
Serum levels of inhibin B, unlike inhibin A and activin A, are not altered in women with preeclampsia.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2001, Volume: 45, Issue:3

    Topics: Activins; Adult; Female; Humans; Inhibins; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Pro

2001
Activin A and activin receptors in gestational tissue from preeclamptic pregnancies.
    The Journal of endocrinology, 2001, Volume: 171, Issue:1

    Topics: Activin Receptors; Activins; Case-Control Studies; Eclampsia; Extraembryonic Membranes; Female; Huma

2001
Serum activin A, inhibin A, and follistatin concentrations in preeclampsia or small for gestational age pregnancies.
    Obstetrics and gynecology, 2002, Volume: 99, Issue:2

    Topics: Activins; Adult; Blood Pressure; Case-Control Studies; Cross-Sectional Studies; Female; Fetal Growth

2002