Page last updated: 2024-10-31

activins and Diseases, Metabolic

activins has been researched along with Diseases, Metabolic in 2 studies

Activins: Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.

Research Excerpts

ExcerptRelevanceReference
"Animal studies in vivo indicate that leptin treatment in extremely leptin-sensitive ob/ob mice reduces body weight exclusively by reducing fat mass and that it increases muscle mass by downregulating myostatin expression."5.15Leptin treatment reduces body fat but does not affect lean body mass or the myostatin-follistatin-activin axis in lean hypoleptinemic women. ( Brinkoetter, M; Magkos, F; Mantzoros, CS; Vamvini, M, 2011)
"Activins and inhibins were first identified by virtue of their ability to regulate follicle-stimulating hormone (FSH) secretion from the anterior pituitary."2.42Activins, myostatin and related TGF-beta family members as novel therapeutic targets for endocrine, metabolic and immune disorders. ( Tsuchida, K, 2004)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brinkoetter, M1
Magkos, F1
Vamvini, M1
Mantzoros, CS1
Tsuchida, K1

Reviews

1 review available for activins and Diseases, Metabolic

ArticleYear
Activins, myostatin and related TGF-beta family members as novel therapeutic targets for endocrine, metabolic and immune disorders.
    Current drug targets. Immune, endocrine and metabolic disorders, 2004, Volume: 4, Issue:2

    Topics: Activins; Animals; Autoimmune Diseases of the Nervous System; Drug Delivery Systems; Endocrine Syste

2004

Trials

1 trial available for activins and Diseases, Metabolic

ArticleYear
Leptin treatment reduces body fat but does not affect lean body mass or the myostatin-follistatin-activin axis in lean hypoleptinemic women.
    American journal of physiology. Endocrinology and metabolism, 2011, Volume: 301, Issue:1

    Topics: Activins; Adipose Tissue; Adult; Body Composition; Body Weight; Double-Blind Method; Down-Regulation

2011