activins has been researched along with Diseases, Metabolic in 2 studies
Activins: Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.
Excerpt | Relevance | Reference |
---|---|---|
"Animal studies in vivo indicate that leptin treatment in extremely leptin-sensitive ob/ob mice reduces body weight exclusively by reducing fat mass and that it increases muscle mass by downregulating myostatin expression." | 5.15 | Leptin treatment reduces body fat but does not affect lean body mass or the myostatin-follistatin-activin axis in lean hypoleptinemic women. ( Brinkoetter, M; Magkos, F; Mantzoros, CS; Vamvini, M, 2011) |
"Activins and inhibins were first identified by virtue of their ability to regulate follicle-stimulating hormone (FSH) secretion from the anterior pituitary." | 2.42 | Activins, myostatin and related TGF-beta family members as novel therapeutic targets for endocrine, metabolic and immune disorders. ( Tsuchida, K, 2004) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Brinkoetter, M | 1 |
Magkos, F | 1 |
Vamvini, M | 1 |
Mantzoros, CS | 1 |
Tsuchida, K | 1 |
1 review available for activins and Diseases, Metabolic
Article | Year |
---|---|
Activins, myostatin and related TGF-beta family members as novel therapeutic targets for endocrine, metabolic and immune disorders.
Topics: Activins; Animals; Autoimmune Diseases of the Nervous System; Drug Delivery Systems; Endocrine Syste | 2004 |
1 trial available for activins and Diseases, Metabolic
Article | Year |
---|---|
Leptin treatment reduces body fat but does not affect lean body mass or the myostatin-follistatin-activin axis in lean hypoleptinemic women.
Topics: Activins; Adipose Tissue; Adult; Body Composition; Body Weight; Double-Blind Method; Down-Regulation | 2011 |