activins has been researched along with Cirrhosis, Liver in 13 studies
Activins: Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine the expression of activin A, a member of the transforming growth factor (TGFbeta) superfamily, recently has been reported to be overexpressed in liver cirrhosis, in the course of carbon tetrachloride-induced rat hepatic fibrosis." | 3.71 | Expression changes of activin A in the development of hepatic fibrosis. ( Cheng, JL; Huang, X; Li, DG; Li, X; Lu, HM; Wang, ZR; Wei, HS; Xu, QF; Zhan, YT; Zhou, X, 2001) |
| "Liver fibrosis is the end stage of almost all chronic liver diseases, such as non-alcoholic fatty liver disease, and at the moment, there is no effective anti-fibrotic therapy available." | 3.01 | Expression and Function of BMP and Activin Membrane-Bound Inhibitor (BAMBI) in Chronic Liver Diseases and Hepatocellular Carcinoma. ( Buechler, C; Mester, P; Treeck, O; Weber, F, 2023) |
| "In patients with non-alcoholic steatohepatitis (NASH, n=38), there were particularly high levels of activin A that were significantly related to the degree of hepatic fibrosis." | 1.35 | A complex role of activin A in non-alcoholic fatty liver disease. ( Aukrust, P; Berge, C; Berge, RK; Birkeland, K; Bjøro, K; Dahl, TB; Damås, JK; Gladhaug, IP; Haaland, T; Halvorsen, B; Haukeland, JW; Konopski, Z; Linnestad, P; Løberg, EM; Yndestad, A, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 3 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 1 |
| Hamang, M | 1 |
| Culver, A | 1 |
| Jiang, H | 1 |
| Yanum, J | 1 |
| Garcia, V | 1 |
| Lee, J | 1 |
| White, E | 1 |
| Kusumanchi, P | 1 |
| Chalasani, N | 1 |
| Liangpunsakul, S | 1 |
| Yaden, BC | 1 |
| Dai, G | 1 |
| Weber, F | 1 |
| Treeck, O | 1 |
| Mester, P | 1 |
| Buechler, C | 1 |
| Chen, Y | 1 |
| Qian, B | 1 |
| Sun, X | 1 |
| Kang, Z | 1 |
| Huang, Z | 1 |
| Ding, Z | 1 |
| Dong, L | 1 |
| Chen, J | 1 |
| Zhang, J | 1 |
| Zang, Y | 1 |
| Manavski, Y | 1 |
| Abel, T | 1 |
| Hu, J | 1 |
| Kleinlützum, D | 1 |
| Buchholz, CJ | 1 |
| Belz, C | 1 |
| Augustin, HG | 1 |
| Boon, RA | 1 |
| Dimmeler, S | 1 |
| Kiagiadaki, F | 1 |
| Kampa, M | 1 |
| Voumvouraki, A | 2 |
| Castanas, E | 1 |
| Kouroumalis, E | 2 |
| Notas, G | 2 |
| Zhang, H | 1 |
| Ju, B | 1 |
| Nie, Y | 1 |
| Song, B | 1 |
| Xu, Y | 1 |
| Gao, P | 1 |
| Ding, ZY | 1 |
| Jin, GN | 1 |
| Wang, W | 1 |
| Sun, YM | 1 |
| Chen, WX | 1 |
| Chen, L | 1 |
| Liang, HF | 1 |
| Datta, PK | 1 |
| Zhang, MZ | 1 |
| Zhang, B | 1 |
| Chen, XP | 1 |
| Yndestad, A | 1 |
| Haukeland, JW | 1 |
| Dahl, TB | 1 |
| Bjøro, K | 1 |
| Gladhaug, IP | 1 |
| Berge, C | 1 |
| Damås, JK | 1 |
| Haaland, T | 1 |
| Løberg, EM | 1 |
| Linnestad, P | 1 |
| Birkeland, K | 1 |
| Konopski, Z | 1 |
| Halvorsen, B | 1 |
| Berge, RK | 1 |
| Aukrust, P | 1 |
| Koulentaki, M | 1 |
| Georgiadou, M | 1 |
| Klironomos, S | 1 |
| Patella, S | 1 |
| Phillips, DJ | 1 |
| Tchongue, J | 1 |
| de Kretser, DM | 1 |
| Sievert, W | 1 |
| Pirisi, M | 1 |
| Fabris, C | 1 |
| Luisi, S | 1 |
| Santuz, M | 1 |
| Toniutto, P | 1 |
| Vitulli, D | 1 |
| Federico, E | 1 |
| Del Forno, M | 1 |
| Mattiuzzo, M | 1 |
| Branca, B | 1 |
| Petraglia, F | 1 |
| Huang, X | 1 |
| Li, DG | 1 |
| Wang, ZR | 1 |
| Wei, HS | 1 |
| Cheng, JL | 1 |
| Zhan, YT | 1 |
| Zhou, X | 1 |
| Xu, QF | 1 |
| Li, X | 1 |
| Lu, HM | 1 |
| Gressner, AM | 1 |
| Weiskirchen, R | 1 |
| Breitkopf, K | 1 |
| Dooley, S | 1 |
2 reviews available for activins and Cirrhosis, Liver
| Article | Year |
|---|---|
Expression and Function of BMP and Activin Membrane-Bound Inhibitor (BAMBI) in Chronic Liver Diseases and Hepatocellular Carcinoma.
Topics: Activins; Bone Morphogenetic Proteins; Carcinoma, Hepatocellular; Humans; Liver Cirrhosis; Liver Neo | 2023 |
Roles of TGF-beta in hepatic fibrosis.
Topics: Activins; Animals; Apoptosis; Humans; Liver; Liver Cirrhosis; Models, Biological; Models, Molecular; | 2002 |
11 other studies available for activins and Cirrhosis, Liver
| Article | Year |
|---|---|
Activin B promotes the initiation and progression of liver fibrosis.
Topics: Activins; Adenosine Diphosphate; Animals; Carbon Tetrachloride; Humans; Liver Cirrhosis; Mice; Nitri | 2022 |
Sox9/INHBB axis-mediated crosstalk between the hepatoma and hepatic stellate cells promotes the metastasis of hepatocellular carcinoma.
Topics: Activins; Animals; Carcinoma, Hepatocellular; Cell Proliferation; Disease Progression; Gene Expressi | 2021 |
Endothelial transcription factor KLF2 negatively regulates liver regeneration via induction of activin A.
Topics: Activins; Animals; Carbon Tetrachloride; Cell Proliferation; Chemical and Drug Induced Liver Injury; | 2017 |
Activin-A causes Hepatic stellate cell activation via the induction of TNFα and TGFβ in Kupffer cells.
Topics: Activins; Aged; Animals; Case-Control Studies; Fibrosis; Hepatic Stellate Cells; Humans; Kupffer Cel | 2018 |
Adenovirus‑mediated knockdown of activin A receptor type 2A attenuates immune‑induced hepatic fibrosis in mice and inhibits interleukin‑17‑induced activation of primary hepatic stellate cells.
Topics: Activin Receptors, Type II; Activins; Adenoviridae; Animals; Cells, Cultured; Concanavalin A; Gene K | 2018 |
Activin A-Smad Signaling Mediates Connective Tissue Growth Factor Synthesis in Liver Progenitor Cells.
Topics: Activins; Adult Stem Cells; Animals; Case-Control Studies; Connective Tissue Growth Factor; HEK293 C | 2016 |
A complex role of activin A in non-alcoholic fatty liver disease.
Topics: Activins; Adult; Cell Line, Tumor; Fatty Liver; Female; Follistatin; Gene Expression; Humans; Liver | 2009 |
Increased serum activin-A differentiates alcoholic from cirrhosis of other aetiologies.
Topics: Activins; Adult; Aged; Carcinoma, Hepatocellular; Female; Hepatitis C, Chronic; Humans; Liver Cirrho | 2012 |
Follistatin attenuates early liver fibrosis: effects on hepatic stellate cell activation and hepatocyte apoptosis.
Topics: Activins; Animals; Apoptosis; Follistatin; Gene Expression Regulation; Hepatocytes; Inhibin-beta Sub | 2006 |
Evaluation of circulating activin-A as a serum marker of hepatocellular carcinoma.
Topics: Activins; Adult; Aged; Aged, 80 and over; alpha-Fetoproteins; Aspartate Aminotransferases; Biomarker | 2000 |
Expression changes of activin A in the development of hepatic fibrosis.
Topics: Activins; Animals; Carbon Tetrachloride; Gene Expression; Immunohistochemistry; Inhibin-beta Subunit | 2001 |