Compounds > activins

activins and Cell Transformation, Neoplastic

activins has been researched along with Cell Transformation, Neoplastic in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.17)18.2507
2000's8 (33.33)29.6817
2010's14 (58.33)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Hanahan, D; Michael, IP; Saghafinia, S1
Chen, L; De Menna, M; Groenewoud, A; Kruithof-de Julio, M; Snaar-Jagalska, BE; Thalmann, GN1
Castellucci, M; Ciarmela, P; Ciavattini, A; Giannubilo, SR; Greco, S; Hinz, B; Islam, MS; Lamanna, P; Petraglia, F; Protic, O1
Hanahan, D; Marinoni, I; Michael, IP; Perren, A; Saghafinia, S; Tichet, M; Zangger, N1
Aicher, A; Cioffi, M; Dorado, J; Hahn, S; Heeschen, C; Hidalgo, M; Lonardo, E; Miranda-Lorenzo, I; Ramirez, JC; Reis Vieira, C; Sainz, B; Sanchez-Ripoll, Y; Trabulo, SM1
Annunziata, CM; Bunch, KP; Gharwan, H1
Andl, CD; Andl, T; El-Rifai, W; Koumangoye, RB; Le Bras, GF; Loomans, HA; Quast, LL; Romero-Morales, AI; Taylor, C; Zaika, AI1
Choy, L; Derynck, R; Knouse, KA; Liu, IM; Schilling, SH; Wang, XF1
Akçetin, Z; Behrens, J; Huber, O; Knaup, K; Sachs, M; Wacker, I; Weiske, J; Wiesener, M1
de Jong, FH; Hofland, J1
Gold, E; Risbridger, G1
Drummond, AE; Fuller, PJ1
Aicher, A; Alcala, S; Balic, A; Bartenstein, P; Berger, F; Cebrián, DÁ; Garcia, E; Heeschen, C; Hermann, PC; Heuchel, R; Hidalgo, M; Huber, S; Löhr, M; Lonardo, E; Miranda-Lorenzo, I; Mueller, MT; Ramirez, JC; Rodriguez-Arabaolaza, I; Torres-Ruíz, R; Zagorac, S1
Antsiferova, M; Dummer, R; Havran, WL; Hohl, D; Huber, M; MacLeod, AS; Meyer, M; Piwko-Czuchra, A; Ramadan, T; Werner, S1
Kang, J; Liu, N; Song, C; Yan, H; Zhu, S1
Gold, E; Ottley, E1
DeFilippis, R; Fessenden, TB; Fordyce, CA; Hwang, ES; Patten, KT; Tlsty, TD; Zhao, J1
Adkins, HB; Benjamin, C; Bianco, C; Chen, LL; Cheung, AE; De Luca, A; Jarpe, M; LePage, D; Miatkowski, K; Normanno, N; Olson, D; Orozco, O; Rayhorn, P; Salomon, D; Sanicola, M; Schiffer, SG; Williams, KP; Zafari, M1
Graff, JM; Li, Q; Loveland, KL; Matzuk, MM; O'Connor, AE1
Hammer, GD; Looyenga, BD1
Hagiwara, K; Hanyu, A; Miyazono, K; Mogi, A; Nagamachi, Y; Nagashima, M; Takenoshita, S; Yagi, K; Yang, K1
Danila, DC; Dickersin, GR; Fletcher, JA; Hedley-Whyte, ET; Johnson, SR; Klibanski, A; Selig, MK; Zhang, X; Zhou, Y1
Woodruff, TK1
Chen, YG; Lee, JM; Lin, SL; Lui, HM; Ying, SY1

Reviews

8 review(s) available for activins and Cell Transformation, Neoplastic

ArticleYear
Activin A in Inflammation, Tissue Repair, and Fibrosis: Possible Role as Inflammatory and Fibrotic Mediator of Uterine Fibroid Development and Growth.
    Seminars in reproductive medicine, 2017, Volume: 35, Issue:6

    Topics: Activin Receptors, Type I; Activin Receptors, Type II; Activins; Cell Transformation, Neoplastic; Female; Humans; Inhibin-beta Subunits; Leiomyoma; Leiomyomatosis; Models, Biological; Myometrium; Signal Transduction; Tumor Burden; Uterine Neoplasms

2017
The role of reproductive hormones in epithelial ovarian carcinogenesis.
    Endocrine-related cancer, 2015, Volume: 22, Issue:6

    Topics: Activins; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma; Cell Differentiation; Cell Transformation, Neoplastic; Chickens; Drug Screening Assays, Antitumor; Epithelial Cells; Fallopian Tubes; Female; Genes, Neoplasm; Genitalia, Female; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Hypothalamo-Hypophyseal System; Immune System; Immunotherapy; Inhibins; Mice; Models, Animal; Models, Biological; Mutation; Neovascularization, Pathologic; NF-kappa B; Ovarian Neoplasms; Primates; Stromal Cells; Tumor Microenvironment

2015
Inhibins and activins: their roles in the adrenal gland and the development of adrenocortical tumors.
    Molecular and cellular endocrinology, 2012, Aug-15, Volume: 359, Issue:1-2

    Topics: Activins; Adrenal Cortex Neoplasms; Adrenal Glands; Animals; Cell Transformation, Neoplastic; Humans; Hyperplasia; Inhibins; TGF-beta Superfamily Proteins

2012
Activins and activin antagonists in the prostate and prostate cancer.
    Molecular and cellular endocrinology, 2012, Aug-15, Volume: 359, Issue:1-2

    Topics: Activins; Animals; Cell Transformation, Neoplastic; Follistatin; Follistatin-Related Proteins; GPI-Linked Proteins; Humans; Inhibins; Intercellular Signaling Peptides and Proteins; Male; Membrane Proteins; Neoplasm Proteins; Prostate; Prostatic Neoplasms

2012
Activin and inhibin, estrogens and NFκB, play roles in ovarian tumourigenesis is there crosstalk?
    Molecular and cellular endocrinology, 2012, Aug-15, Volume: 359, Issue:1-2

    Topics: Activin Receptors; Activins; Animals; Cell Transformation, Neoplastic; Female; Humans; Inhibins; NF-kappa B; Ovarian Neoplasms; Receptor Cross-Talk; Receptors, Estrogen; Signal Transduction

2012
Insensitivity to the growth inhibitory effects of activin A: an acquired capability in prostate cancer progression.
    Cytokine & growth factor reviews, 2012, Volume: 23, Issue:3

    Topics: Activins; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Growth Inhibitors; Humans; Male; MicroRNAs; Prostatic Neoplasms

2012
Role of inhibins and activins in ovarian cancer.
    Cancer treatment and research, 2002, Volume: 107

    Topics: Activins; Cell Transformation, Neoplastic; Female; Granulosa Cell Tumor; Humans; Inhibins; Ovarian Follicle; Ovarian Neoplasms; Ovary; Signal Transduction

2002
Regulation of cell proliferation, apoptosis, and carcinogenesis by activin.
    Experimental biology and medicine (Maywood, N.J.), 2002, Volume: 227, Issue:2

    Topics: Activin Receptors; Activins; Animals; Apoptosis; Cell Division; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Humans; Inhibin-beta Subunits; Signal Transduction; Trans-Activators; Tumor Suppressor Protein p53

2002

Other Studies

16 other study(ies) available for activins and Cell Transformation, Neoplastic

ArticleYear
A set of microRNAs coordinately controls tumorigenesis, invasion, and metastasis.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 11-26, Volume: 116, Issue:48

    Topics: Activin Receptors, Type I; Activins; Algorithms; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Computational Biology; Doxycycline; Gene Expression Regulation, Neoplastic; Humans; LDL-Receptor Related Proteins; Liver Neoplasms; Membrane Transport Proteins; Mice; MicroRNAs; Neuroendocrine Tumors; Pancreatic Neoplasms; Prognosis; Receptors, LDL; Xenograft Model Antitumor Assays

2019
A NF-ĸB-Activin A signaling axis enhances prostate cancer metastasis.
    Oncogene, 2020, Volume: 39, Issue:8

    Topics: Activins; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Staging; Neoplastic Stem Cells; NF-kappa B; PC-3 Cells; Prostatic Neoplasms; Signal Transduction; Smad Proteins; Up-Regulation; Zebrafish

2020
ALK7 Signaling Manifests a Homeostatic Tissue Barrier That Is Abrogated during Tumorigenesis and Metastasis.
    Developmental cell, 2019, 05-06, Volume: 49, Issue:3

    Topics: Activin Receptors, Type I; Activins; Animals; Apoptosis; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Transformation, Neoplastic; Female; Heterografts; Homeostasis; Humans; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, SCID; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta; Tumor Microenvironment

2019
The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells.
    Gut, 2015, Volume: 64, Issue:12

    Topics: Activins; Animals; Antimetabolites, Antineoplastic; Carcinoma, Pancreatic Ductal; Cell Cycle Checkpoints; Cell Self Renewal; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p57; Deoxycytidine; Down-Regulation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Mice; Mice, Nude; MicroRNAs; Neoplastic Stem Cells; Nodal Protein; Pancreatic Neoplasms; RNA, Long Noncoding; Signal Transduction; T-Box Domain Proteins; Transcriptome; Transforming Growth Factor beta1

2015
Activin a signaling regulates cell invasion and proliferation in esophageal adenocarcinoma.
    Oncotarget, 2015, Oct-27, Volume: 6, Issue:33

    Topics: Activins; Adenocarcinoma; Barrett Esophagus; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Enzyme-Linked Immunosorbent Assay; Esophageal Neoplasms; Fluorescent Antibody Technique; Humans; Neoplasm Invasiveness

2015
TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch.
    The EMBO journal, 2009, Jan-21, Volume: 28, Issue:2

    Topics: Activins; Animals; Benzamides; Bone Morphogenetic Proteins; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Dioxoles; Humans; Mice; Phosphorylation; Protein Binding; Protein Isoforms; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad1 Protein; Smad5 Protein; Transforming Growth Factor beta

2009
Key role for activin B in cellular transformation after loss of the von Hippel-Lindau tumor suppressor.
    Molecular and cellular biology, 2009, Volume: 29, Issue:7

    Topics: Activins; Animals; Carcinoma, Renal Cell; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cell Transformation, Neoplastic; Extracellular Matrix; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Mice; Mice, Nude; Neoplasm Invasiveness; Rats; RNA, Small Interfering; Up-Regulation; Von Hippel-Lindau Tumor Suppressor Protein; Xenograft Model Antitumor Assays

2009
Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.
    Cell stem cell, 2011, Nov-04, Volume: 9, Issue:5

    Topics: AC133 Antigen; Activins; Animals; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Female; Gene Targeting; Glycoproteins; Humans; Mice; Mice, Nude; Neoplastic Stem Cells; Nodal Protein; Pancreatic Neoplasms; Peptides; Pluripotent Stem Cells; Signal Transduction; Spheroids, Cellular; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2011
Activin enhances skin tumourigenesis and malignant progression by inducing a pro-tumourigenic immune cell response.
    Nature communications, 2011, Dec-06, Volume: 2

    Topics: Activins; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Epidermis; Gene Expression Regulation, Neoplastic; Humans; Keratinocytes; Langerhans Cells; Mice; Mice, Transgenic; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; T-Lymphocytes, Regulatory; Wound Healing

2011
Bone morphogenetic protein (BMP) signaling regulates mitotic checkpoint protein levels in human breast cancer cells.
    Cellular signalling, 2012, Volume: 24, Issue:4

    Topics: Activins; Benzamides; Bone Morphogenetic Proteins; Breast Neoplasms; Calcium-Binding Proteins; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytoskeletal Proteins; Dioxoles; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Mad2 Proteins; Nocodazole; Nuclear Proteins; Plasmids; Poly-ADP-Ribose Binding Proteins; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Repressor Proteins; Signal Transduction; Transfection; Transforming Growth Factor beta

2012
Cell-extrinsic consequences of epithelial stress: activation of protumorigenic tissue phenotypes.
    Breast cancer research : BCR, 2012, Dec-07, Volume: 14, Issue:6

    Topics: Actins; Activins; Carcinoma, Intraductal, Noninfiltrating; Cell Movement; Cell Transformation, Neoplastic; Cells, Cultured; Coculture Techniques; Cyclooxygenase 2; Dinoprostone; DNA Damage; DNA Repair; Epithelial Cells; Fibroblasts; Glycolysis; Humans; Mammary Glands, Human; Stress, Physiological; Telomere; Telomere Homeostasis

2012
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo.
    The Journal of clinical investigation, 2003, Volume: 112, Issue:4

    Topics: Activin Receptors, Type I; Activins; Animals; Antibodies, Monoclonal; Breast Neoplasms; Cell Division; Cell Separation; Cell Transformation, Neoplastic; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epitopes; Flow Cytometry; GPI-Linked Proteins; Humans; Immunoblotting; Immunoglobulin G; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Ligands; Male; Membrane Glycoproteins; Mice; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Nodal Protein; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Transfection; Transforming Growth Factor beta; Tumor Cells, Cultured

2003
SMAD3 regulates gonadal tumorigenesis.
    Molecular endocrinology (Baltimore, Md.), 2007, Volume: 21, Issue:10

    Topics: Activins; Animals; Cell Transformation, Neoplastic; Female; Follicle Stimulating Hormone; Inhibins; Male; Mice; Mice, Knockout; Ovarian Neoplasms; RNA, Messenger; Smad3 Protein; Testicular Neoplasms; Wasting Syndrome; Weight Loss

2007
Genetic removal of Smad3 from inhibin-null mice attenuates tumor progression by uncoupling extracellular mitogenic signals from the cell cycle machinery.
    Molecular endocrinology (Baltimore, Md.), 2007, Volume: 21, Issue:10

    Topics: Activins; Adrenal Cortex; Adrenal Cortex Neoplasms; Animals; Cell Cycle; Cell Transformation, Neoplastic; Cyclin D2; Cyclins; Down-Regulation; Female; Follicle Stimulating Hormone; Gene Expression Profiling; Gonadotropins; Inhibins; Insulin-Like Growth Factor I; Male; Mice; Mice, Knockout; Neoplastic Stem Cells; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Repressor Proteins; Smad3 Protein; Testicular Neoplasms

2007
Characterization of the MADH2/Smad2 gene, a human Mad homolog responsible for the transforming growth factor-beta and activin signal transduction pathway.
    Genomics, 1998, Feb-15, Volume: 48, Issue:1

    Topics: Activins; Amino Acid Sequence; Animals; Base Sequence; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Blotting, Northern; Cell Transformation, Neoplastic; COS Cells; DNA-Binding Proteins; Exons; Humans; Inhibins; Introns; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; Repressor Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Signal Transduction; Smad2 Protein; Trans-Activators; Transforming Growth Factor beta

1998
A human pituitary tumor-derived folliculostellate cell line.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:3

    Topics: Activin Receptors; Activins; Adenoma; Aged; Blotting, Western; Cell Transformation, Neoplastic; Chromosomes; Enzyme-Linked Immunosorbent Assay; Follistatin; Glycoproteins; Growth Substances; Humans; Immunohistochemistry; Inhibins; Luciferases; Male; Microscopy, Electron; Mutation; Pituitary Neoplasms; Receptors, Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2000