activins has been researched along with Cancer of Granulosa Cells in 15 studies
Activins: Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ovarian juvenile granulosa cell tumors are a rare cause of sexual precocity." | 2.39 | Immunoreactive inhibin, müllerian inhibitory substance, and activin as biochemical markers for juvenile granulosa cell tumors. ( Gitelman, SE; Silverman, LA, 1996) |
| "In patient PP, a residual tumor was found 6 years after primary surgery; at the time A levels were elevated, while inhibin levels remained low." | 1.32 | Activin B in patients with granulosa cell tumors: serum levels in comparison to inhibin. ( Bläuer, M; Puistola, U; Tuohimaa, P; Vihko, KK, 2003) |
| "None of the patients with an epithelial ovarian cancer presented an increase of serum inhibin B." | 1.30 | Inhibin B is the major form of inhibin/activin family secreted by granulosa cell tumors. ( Bidart, JM; Lhomme, C; Luisi, S; Pautier, P; Petraglia, F; Rey, R; Sabourin, JC, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (40.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reader, KL | 1 |
| Marino, FE | 1 |
| Nicholson, HD | 1 |
| Risbridger, GP | 1 |
| Gold, EJ | 1 |
| McTavish, KJ | 1 |
| Nonis, D | 1 |
| Hoang, YD | 1 |
| Shimasaki, S | 1 |
| Cheng, JC | 1 |
| Chang, HM | 1 |
| Qiu, X | 1 |
| Fang, L | 1 |
| Leung, PC | 1 |
| Bilandzic, M | 1 |
| Chu, S | 2 |
| Farnworth, PG | 1 |
| Harrison, C | 1 |
| Nicholls, P | 1 |
| Wang, Y | 1 |
| Escalona, RM | 1 |
| Fuller, PJ | 2 |
| Findlay, JK | 1 |
| Stenvers, KL | 1 |
| Suresh, PS | 1 |
| Rajan, T | 1 |
| Tsutsumi, R | 1 |
| Vihko, KK | 2 |
| Bläuer, M | 2 |
| Puistola, U | 1 |
| Tuohimaa, P | 1 |
| Gurusinghe, CJ | 1 |
| Healy, DL | 1 |
| Jobling, T | 2 |
| Mamers, P | 2 |
| Burger, HG | 3 |
| Silverman, LA | 1 |
| Gitelman, SE | 1 |
| Arora, DS | 1 |
| Cooke, IE | 1 |
| Ganesan, TS | 1 |
| Ramsdale, J | 1 |
| Manek, S | 1 |
| Charnock, FM | 1 |
| Groome, NP | 1 |
| Wells, M | 1 |
| Petraglia, F | 1 |
| Luisi, S | 1 |
| Pautier, P | 1 |
| Sabourin, JC | 1 |
| Rey, R | 1 |
| Lhomme, C | 1 |
| Bidart, JM | 1 |
| Rahman, NA | 1 |
| Huhtaniemi, I | 1 |
| Woodruff, TK | 1 |
| Fikret, S | 1 |
| Robertson, DM | 1 |
| Stephenson, T | 1 |
| Pruysers, E | 1 |
| McCloud, P | 1 |
| Tsigos, A | 1 |
| Groome, N | 1 |
| McNeilage, J | 1 |
| Healy, D | 1 |
6 reviews available for activins and Cancer of Granulosa Cells
| Article | Year |
|---|---|
New targets for old hormones: inhibins clinical role revisited.
Topics: Activins; Animals; Bone and Bones; Cattle; Female; Follicle Stimulating Hormone; Granulosa Cell Tumo | 2011 |
Immunoreactive inhibin, müllerian inhibitory substance, and activin as biochemical markers for juvenile granulosa cell tumors.
Topics: Activins; Anti-Mullerian Hormone; Biomarkers, Tumor; Child; Child, Preschool; Female; Glycoproteins; | 1996 |
[Activins and inhibins--from laboratory to clinics].
Topics: Activins; Animals; Female; Fertilization in Vitro; Forecasting; Granulosa Cell Tumor; Humans; Infert | 1997 |
Role of inhibins and activins in ovarian cancer.
Topics: Activins; Cell Transformation, Neoplastic; Female; Granulosa Cell Tumor; Humans; Inhibins; Ovarian F | 2002 |
Molecular pathogenesis of granulosa cell tumours.
Topics: Activin Receptors; Activins; Animals; Female; Gene Expression Regulation, Neoplastic; Granulosa Cell | 2002 |
Inhibins/activins as diagnostic markers for ovarian cancer.
Topics: Activins; Antibodies, Monoclonal; Biomarkers, Tumor; Female; Follicle Stimulating Hormone; Granulosa | 2002 |
9 other studies available for activins and Cancer of Granulosa Cells
| Article | Year |
|---|---|
Role of activin C in normal ovaries and granulosa cell tumours of mice and humans.
Topics: Activins; Animals; Female; Granulosa Cell Tumor; Granulosa Cells; Humans; Inhibins; Mice; Ovarian Fo | 2018 |
Granulosa cell tumor mutant FOXL2C134W suppresses GDF-9 and activin A-induced follistatin transcription in primary granulosa cells.
Topics: Activins; Animals; Cells, Cultured; Female; Follistatin; Forkhead Box Protein L2; Forkhead Transcrip | 2013 |
FOXL2-induced follistatin attenuates activin A-stimulated cell proliferation in human granulosa cell tumors.
Topics: Activins; Cell Proliferation; Down-Regulation; Follistatin; Forkhead Box Protein L2; Forkhead Transc | 2014 |
Loss of betaglycan contributes to the malignant properties of human granulosa tumor cells.
Topics: Activins; Cell Adhesion; Cell Line, Tumor; Female; Gene Silencing; Granulosa Cell Tumor; Humans; Inh | 2009 |
Activin B in patients with granulosa cell tumors: serum levels in comparison to inhibin.
Topics: Activins; Adolescent; Biological Assay; Disease Progression; Female; Granulosa Cell Tumor; Humans; I | 2003 |
Inhibin and activin are demonstrable by immunohistochemistry in ovarian tumor tissue.
Topics: Activins; Adenocarcinoma; Aged; Female; Granulosa Cell Tumor; Growth Substances; Humans; Immune Sera | 1995 |
Immunohistochemical expression of inhibin/activin subunits in epithelial and granulosa cell tumours of the ovary.
Topics: Activins; Adult; Aged; Biomarkers, Tumor; Female; Granulosa Cell Tumor; Growth Substances; Humans; I | 1997 |
Inhibin B is the major form of inhibin/activin family secreted by granulosa cell tumors.
Topics: Activins; Adult; Anti-Mullerian Hormone; Female; Glycoproteins; Granulosa Cell Tumor; Growth Inhibit | 1998 |
Hormonal regulation of proliferation of granulosa and Leydig cell lines derived from gonadal tumors of transgenic mice expressing the inhibin-alpha subunit promoter/simian virus 40 T-antigen fusion gene.
Topics: Activins; Animals; Antigens, Polyomavirus Transforming; Artificial Gene Fusion; DNA, Neoplasm; Femal | 1999 |