activins has been researched along with Cancer of Endometrium in 10 studies
Activins: Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "High-risk type II endometrial cancers account for ~30% of cases but ~75% of deaths due, in part, to their tendency to metastasize." | 1.43 | Activin B promotes endometrial cancer cell migration by down-regulating E-cadherin via SMAD-independent MEK-ERK1/2-SNAIL signaling. ( Cheng, JC; Klausen, C; Leung, PC; Xiong, S, 2016) |
| "The proliferations of the 3 endometrial cancer cells were completely unaffected by activin A, whereas it suppressed the cell proliferation of a human ovarian endometrioid adenocarcinoma cell line, OVK-18, in a dose-dependent manner." | 1.32 | Expression and function of activin receptors in human endometrial adenocarcinoma cells. ( Minami, S; Otani, T; Tanaka, T; Toujima, S; Umesaki, N; Yamoto, M, 2003) |
| "Human endometrial cancer cells express both activin receptor and TGF-beta receptor, and TGF-beta1 utilizes the same intracellular signaling molecules as activin A." | 1.32 | Activin A inhibits growth-inhibitory signals by TGF-beta1 in differentiated human endometrial adenocarcinoma cells. ( Tanaka, T; Toujima, S; Umesaki, N, 2004) |
| "controls)." | 1.30 | Expression and secretion of inhibin and activin in normal and neoplastic uterine tissues. High levels of serum activin A in women with endometrial and cervical carcinoma. ( Di Blasio, AM; Florio, P; Gadducci, A; Gallo, R; Genazzani, AR; Luisi, S; Petraglia, F; Vale, W; Viganò, P, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Q | 1 |
| Xiong, S | 1 |
| Klausen, C | 1 |
| Cheng, JC | 1 |
| Leung, PC | 1 |
| Li, H | 1 |
| Huang, F | 1 |
| Tanaka, T | 2 |
| Toujima, S | 2 |
| Otani, T | 2 |
| Minami, S | 2 |
| Yamoto, M | 2 |
| Umesaki, N | 3 |
| Florio, P | 2 |
| Rossi, M | 1 |
| Sigurdardottir, M | 1 |
| Ciarmela, P | 1 |
| Luisi, S | 2 |
| Viganò, P | 2 |
| Grasso, D | 1 |
| Fiore, G | 1 |
| Cobellis, L | 1 |
| Di Blasio, AM | 2 |
| Petraglia, F | 2 |
| Kimura, F | 1 |
| Takebayashi, K | 1 |
| Takahashi, K | 1 |
| Noda, Y | 1 |
| Gallo, R | 1 |
| Gadducci, A | 1 |
| Genazzani, AR | 1 |
| Vale, W | 1 |
| Di Simone, N | 1 |
| Schneyer, AL | 1 |
| Caliandro, D | 1 |
| Castellani, R | 1 |
| Caruso, A | 1 |
3 reviews available for activins and Cancer of Endometrium
| Article | Year |
|---|---|
[Activin and activin receptors in related gynecologic and obstetric diseases].
Topics: Activin Receptors; Activins; Animals; Endometrial Neoplasms; Endometriosis; Female; Humans; Ovarian | 2010 |
Paracrine regulation of endometrial function: interaction between progesterone and corticotropin-releasing factor (CRF) and activin A.
Topics: Activins; Cell Differentiation; Cell Division; Corticotropin-Releasing Hormone; Endometrial Neoplasm | 2003 |
[Activins and uterine endometrium].
Topics: Activin Receptors; Activins; Adenocarcinoma; Embryo Implantation; Endometrial Neoplasms; Endometrium | 2006 |
7 other studies available for activins and Cancer of Endometrium
| Article | Year |
|---|---|
Tumor-suppressive signaling in the uterus.
Topics: Activins; Animals; Endometrial Neoplasms; Female; Humans; Mice; Signal Transduction; Uterus | 2019 |
Activin B promotes endometrial cancer cell migration by down-regulating E-cadherin via SMAD-independent MEK-ERK1/2-SNAIL signaling.
Topics: Activins; Antigens, CD; Cadherins; Cell Line, Tumor; Cell Movement; Endometrial Neoplasms; Extracell | 2016 |
Expression and function of activin receptors in human endometrial adenocarcinoma cells.
Topics: Activin Receptors; Activins; Adenocarcinoma; Apoptosis; Cell Division; Cell Line, Tumor; Cell Membra | 2003 |
Activin A inhibits growth-inhibitory signals by TGF-beta1 in differentiated human endometrial adenocarcinoma cells.
Topics: Activins; Adenocarcinoma; Cell Differentiation; Cell Division; Cell Line, Tumor; Endometrial Neoplas | 2004 |
Expression and secretion of inhibin and activin in normal and neoplastic uterine tissues. High levels of serum activin A in women with endometrial and cervical carcinoma.
Topics: Activin Receptors; Activins; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Case-Control Studies; E | 1998 |
Production of activin A in hyperplasia and adenocarcinoma of the human endometrium.
Topics: Activins; Adenocarcinoma; Adult; Aged; Endometrial Hyperplasia; Endometrial Neoplasms; Enzyme-Linked | 2001 |
Regulation of endometrial adenocarcinoma cell proliferation by Activin-A and its modulation by 17beta-estradiol.
Topics: Activin Receptors, Type I; Activin Receptors, Type II; Activins; Adenocarcinoma; Apoptosis; bcl-2-As | 2002 |