activins and Cachexia

activins has been researched along with Cachexia in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (8.33)	18.2507
2000's	5 (13.89)	29.6817
2010's	20 (55.56)	24.3611
2020's	8 (22.22)	2.80

Authors

Authors	Studies
Koniaris, LG; Liu, S; Liu, Y; Narasimhan, A; Shahda, S; Silverman, LM; Wan, J; Young, AR; Zhong, X; Zimmers, TA	1
Hagg, A; Harrison, CA; O'Shea, E; Walton, KL	1
Andersen, S; Bjørkøy, G; Grønberg, BH; Hatakeyama, S; Jacobi, C; Kim, J; Lach-Trifilieff, E; Lambert, C; Moestue, S; Nonstad, U; Pettersen, K; Schilb, A; van der Veen, A	1
Ilonen, I; Järvinen, T; Koli, K; Lauri, H; Lemström, K; Myllärniemi, M; Ollila, H; Paajanen, J; Räsänen, J; Ritvos, O; Rouvinen, E; Sutinen, E	1
Ballarò, R; Baumann, M; Euro, L; Hentilä, J; Hulmi, JJ; Lalowski, M; Lautaoja, JH; Nissinen, TA; Penna, F; Pirinen, E; Pöllänen, N; Ritvos, O; Soliymani, R	1
Falch, D; Grusch, M; Hoda, MA; Pany, L; Ries, A; Schelch, K	1
Cao, Z; Glab, J; Hoogenraad, NJ; Jose, I; Osellame, LD; Puthalakath, H	1
Boor, P; Cohen, CD; Eichinger, F; Hoxha, E; Huber, TB; Kilic, T; Klinkhammer, BM; Kretz, O; Kretzler, M; Kylies, D; Lindenmeyer, MT; Liu, S; Lu, S; Martin, IV; Matsakas, A; Menon, R; Meyer, C; Mitchell, R; Nair, V; Omairi, S; Ostendorf, T; Paolini, A; Pasternack, A; Patel, K; Puelles, VG; Ritvos, O; Sandri, M; Solagna, F; Tezze, C; Tharaux, PL; Turner, JE; Wanner, N; Wiesch, JSZ; Wu, G; Zhao, Y	1
de Barsy, M; Gruson, D; Lause, P; Loumaye, A; Nachit, M; Thissen, JP; Trefois, P; van Maanen, A	1
Constam, DB; Donovan, P; Dubey, OA; Kallioinen, S; Muehlethaler, K; Müller, P; Rimoldi, D; Rogers, KW	1
Cadena, SM; Chen, H; Chen, Z; Glass, DJ; Gong, C; Hadcock, JR; Jones, JE; Lach-Trifilieff, E; Vickers, C; Wang, SX; Wang, X	1
Chen, R; Ding, H; Fu, X; Gui, X; Ji, X; Zhou, G	1
Ceppa, EP; Couch, ME; House, MG; Jiang, G; Jiang, Y; Koniaris, LG; Liu, J; Liu, Y; Nakeeb, A; Poirier, C; Pons, M; Sandusky, GE; Schmidt, CM; Shahda, S; Zhong, X; Zimmers, TA; Zyromski, NJ	1
Arnold, Q; Chen, JL; Colgan, TD; Gregorevic, P; Hagg, A; Harrison, CA; Kelly, E; La, M; Lovrecz, G; Lu, L; Qian, H; Walton, KL	1
Loumaye, A; Thissen, JP	1
Gold, E; Marino, FE; Risbridger, G	1
Chen, JL; Gregorevic, P; Harrison, CA; Lynch, GS; Makanji, Y; Murphy, KT; Qian, H; Thomson, RE; Walton, KL; Winbanks, CE	1
de Velasco, MA; Fujita, Y; Hayashi, H; Kitano, M; Kogita, A; Kudo, M; Nishio, K; Okuno, K; Sakai, K; Sakamoto, H; Terashima, M; Togashi, Y; Tomida, S	1
de Barsy, M; Frateur, L; Gruson, D; Lause, P; Loumaye, A; Nachit, M; Thissen, JP; Trefois, P; van Maanen, A	1
Adachi, S; Handa, O; Ishikawa, T; Itoh, Y; Kamada, K; Katada, K; Kimura, R; Kokura, S; Matsuyama, T; Mizushima, K; Naito, Y; Oka, K; Okajima, M; Okayama, T; Sakai, H; Sakamoto, N; Takagi, T; Uchiyama, K	1
Chen, JL; Colgan, TD; Gregorevic, P; Hagg, A; Harrison, CA; Qian, H; Walton, KL; Watt, MJ	1
Bertona, M; Emanuele, E; Fiuza-Luces, C; Lucia, A; Morales, JS; Pareja-Galeano, H; Sanchis-Gomar, F	1
Boone, T; Chen, Q; Goldberg, AL; Han, HQ; Jiao, Q; Kwak, KS; Lacey, DL; Lu, J; Rosenfeld, R; Simonet, WS; Song, Y; Wang, JL; Zhou, X	1
Vanchieri, C	1
Mathew, SJ	1
Bonala, S; Kambadur, R; Lokireddy, S; McFarlane, C; Sharma, M; Sze, SK; Wei, M; Wijesoma, IW	1
Fearon, KC; Glass, DJ; Guttridge, DC	1
Gold, E; Harrison, C; Makanji, Y; Marino, FE; Risbridger, G	1
Bavers, DL; Beuschlein, F; Bleasdale, SE; Hammer, GD; Looyenga, BD; Mutch, C; Nilson, JH; Parlow, AF	1
Brown, CA; Chen, L; Matzuk, MM; Wu, X; Yan, C	1
Gray, PC; Harrison, CA; Robertson, DM; Vale, WW	1
Kumar, R; Li, Q; Loveland, KL; Matzuk, MM; O'Connor, AE; Seehra, JS; Underwood, K	1
Bradley, A; Finegold, MJ; Krummen, L; Lu, H; Mather, JP; Matzuk, MM	1
Bradley, A; Coerver, KA; Finegold, MJ; Mather, J; Matzuk, MM; Woodruff, TK	1
Matzuk, MM; Shou, W; Woodruff, TK	1
Davies, MV; Esquela, AF; Haynes, P; Koniaris, LG; Lee, SJ; McPherron, AC; Tomkinson, KN; Wolfman, NM; Zimmers, TA	1

Reviews

5 review(s) available for activins and Cachexia

Article	Year
Activin A: an emerging target for improving cancer treatment? Expert opinion on therapeutic targets, 2020, Volume: 24, Issue:10 Topics: Activins; Animals; Biomarkers, Tumor; Cachexia; Drug Resistance, Neoplasm; Humans; Molecular Targeted Therapy; Neoplasms; Neovascularization, Pathologic; Tumor Microenvironment	2020
[Role of Activin A and Myostatin in cancer cachexia]. Annales d'endocrinologie, 2013, Volume: 74, Issue:2 Topics: Activins; Animals; Cachexia; Humans; Mice; Mice, Knockout; Myostatin; Neoplasms	2013
The therapeutic potential of blocking the activin signalling pathway. Cytokine & growth factor reviews, 2013, Volume: 24, Issue:5 Topics: Activins; Animals; Antineoplastic Agents; Cachexia; Cell Proliferation; Humans; Musculoskeletal Diseases; Neoplasm Proteins; Neoplasms, Gonadal Tissue; Neuromuscular Diseases; Signal Transduction; Transforming Growth Factor beta	2013
Cancer cachexia: mediators, signaling, and metabolic pathways. Cell metabolism, 2012, Aug-08, Volume: 16, Issue:2 Topics: Activins; Cachexia; Humans; Interleukin-6; Lipolysis; Metabolic Networks and Pathways; Models, Biological; Muscular Atrophy; Myostatin; Neoplasms; Signal Transduction; Tumor Necrosis Factor-alpha	2012
Antagonists of activin signaling: mechanisms and potential biological applications. Trends in endocrinology and metabolism: TEM, 2005, Volume: 16, Issue:2 Topics: Activins; Animals; Cachexia; Hormone Antagonists; Humans; Neoplasms; Signal Transduction; Wound Healing	2005

Other Studies

31 other study(ies) available for activins and Cachexia

Article	Year
Sex specificity of pancreatic cancer cachexia phenotypes, mechanisms, and treatment in mice and humans: role of Activin. Journal of cachexia, sarcopenia and muscle, 2022, Volume: 13, Issue:4 Topics: Activins; Adenocarcinoma; Animals; Cachexia; Carcinoma, Pancreatic Ductal; Estradiol; Female; Follistatin-Related Proteins; Humans; Male; Mice; Muscle, Skeletal; Muscular Atrophy; Pancreatic Neoplasms; Phenotype; Sex Factors	2022
Targeting activins and inhibins to treat reproductive disorders and cancer cachexia. The Journal of endocrinology, 2023, 07-01, Volume: 258, Issue:1 Topics: Activins; Animals; Cachexia; Female; Follicle Stimulating Hormone; Humans; Inhibins; Mice; Neoplasms; Pregnancy	2023
Autocrine activin A signalling in ovarian cancer cells regulates secretion of interleukin 6, autophagy, and cachexia. Journal of cachexia, sarcopenia and muscle, 2020, Volume: 11, Issue:1 Topics: Activins; Animals; Autocrine Communication; Autophagy; Cachexia; Disease Models, Animal; Female; Humans; Interleukin-6; Mice; Ovarian Neoplasms; Signal Transduction	2020
Elevated Circulating Activin A Levels in Patients With Malignant Pleural Mesothelioma Are Related to Cancer Cachexia and Reduced Response to Platinum-based Chemotherapy. Clinical lung cancer, 2020, Volume: 21, Issue:3 Topics: Activins; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cachexia; Carcinoma, Non-Small-Cell Lung; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Mesothelioma, Malignant; Middle Aged; Platinum; Pleural Neoplasms; Prognosis; Prospective Studies; Retrospective Studies; ROC Curve	2020
Muscle NAD Molecular metabolism, 2020, Volume: 41 Topics: Activin Receptors; Activins; Acute-Phase Proteins; Animals; Cachexia; Cell Line, Tumor; Disease Models, Animal; Male; Mice; Mitochondria; Muscle, Skeletal; Muscular Atrophy; Myostatin; NAD; Oxidative Phosphorylation; Serpins	2020
Generation of reporter cell lines for factors inducing muscle wasting in cancer cachexia. Analytical biochemistry, 2020, 10-01, Volume: 606 Topics: Activins; Animals; Cachexia; Cell Line, Transformed; Genes, Reporter; Green Fluorescent Proteins; Humans; Mice; Mice, Inbred C57BL; Muscular Atrophy; Myoblasts; Myostatin; Neoplasms; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases	2020
Pro-cachectic factors link experimental and human chronic kidney disease to skeletal muscle wasting programs. The Journal of clinical investigation, 2021, 06-01, Volume: 131, Issue:11 Topics: Activin Receptors, Type II; Activins; Animals; Cachexia; Disease Models, Animal; HEK293 Cells; Humans; Mice; Mice, Knockout; Muscle, Skeletal; Muscular Atrophy; Renal Insufficiency, Chronic; Wasting Syndrome	2021
Circulating Activin A predicts survival in cancer patients. Journal of cachexia, sarcopenia and muscle, 2017, Volume: 8, Issue:5 Topics: Activins; Adipose Tissue; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Body Composition; Cachexia; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Muscle, Skeletal; Neoplasm Staging; Neoplasms; Nutritional Status; Organ Size; Prognosis; Young Adult	2017
Paracrine Activin-A Signaling Promotes Melanoma Growth and Metastasis through Immune Evasion. The Journal of investigative dermatology, 2017, Volume: 137, Issue:12 Topics: Activins; Animals; Cachexia; Cell Cycle; Disease Progression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immune Evasion; Immune System; Ki-67 Antigen; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Neovascularization, Pathologic; Phenotype; Signal Transduction; Skin Neoplasms; Tumor Microenvironment	2017
Supraphysiologic Administration of GDF11 Induces Cachexia in Part by Upregulating GDF15. Cell reports, 2018, 02-06, Volume: 22, Issue:6 Topics: Activins; Animals; Bone Morphogenetic Proteins; Cachexia; Growth Differentiation Factor 15; Growth Differentiation Factors; Male; Mice; Mice, Inbred C57BL; Up-Regulation	2018
Elevated serum Activin A in chronic obstructive pulmonary disease with skeletal muscle wasting. Clinics (Sao Paulo, Brazil), 2019, Volume: 74 Topics: Activins; Adult; Aged; Body Mass Index; Cachexia; Case-Control Studies; Female; Humans; Inhibin-beta Subunits; Male; Middle Aged; Muscle, Skeletal; Muscular Atrophy; Pulmonary Disease, Chronic Obstructive; Tumor Necrosis Factor-alpha	2019
The systemic activin response to pancreatic cancer: implications for effective cancer cachexia therapy. Journal of cachexia, sarcopenia and muscle, 2019, Volume: 10, Issue:5 Topics: Activin Receptors, Type II; Activins; Animals; Biomarkers; Body Weights and Measures; Cachexia; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Disease Management; Disease Models, Animal; Gene Expression; Humans; Immunohistochemistry; Mice; Muscle Fibers, Skeletal; Muscular Atrophy; Pancreatic Neoplasms; Prognosis; Proportional Hazards Models	2019
Activin A-Induced Cachectic Wasting Is Attenuated by Systemic Delivery of Its Cognate Propeptide in Male Mice. Endocrinology, 2019, 10-01, Volume: 160, Issue:10 Topics: Activins; Animals; Cachexia; CHO Cells; Cricetinae; Cricetulus; Kidney; Liver; Male; Mice; Muscle, Skeletal; Myocardium; Organ Size; Peptides	2019
Elevated expression of activins promotes muscle wasting and cachexia. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2014, Volume: 28, Issue:4 Topics: Activin Receptors, Type II; Activins; Animals; Blotting, Western; Cachexia; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Dependovirus; Gene Expression; Genetic Vectors; Humans; MCF-7 Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Myostatin; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; SKP Cullin F-Box Protein Ligases	2014
Activin signal promotes cancer progression and is involved in cachexia in a subset of pancreatic cancer. Cancer letters, 2015, Jan-28, Volume: 356, Issue:2 Pt B Topics: Activins; Aged; Aged, 80 and over; Animals; Apoptosis; Biomarkers, Tumor; Blotting, Western; Cachexia; Cell Proliferation; Disease Progression; Female; Humans; Immunoenzyme Techniques; Lymphatic Metastasis; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Staging; Pancreatic Neoplasms; Prognosis; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Survival Rate; Tumor Cells, Cultured; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays	2015
Role of Activin A and myostatin in human cancer cachexia. The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:5 Topics: Activins; Adult; Aged; Aged, 80 and over; Body Composition; Cachexia; Colorectal Neoplasms; Cross-Sectional Studies; Female; Humans; Lung Neoplasms; Male; Middle Aged; Myostatin; Prospective Studies; Quality of Life	2015
Tumor inoculation site affects the development of cancer cachexia and muscle wasting. International journal of cancer, 2015, Dec-01, Volume: 137, Issue:11 Topics: Activins; Animals; Cachexia; Cell Line, Tumor; Disease Models, Animal; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Myocardium; RNA, Messenger; SKP Cullin F-Box Protein Ligases; Transforming Growth Factor beta; Tripartite Motif Proteins; Tumor Microenvironment; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases	2015
Differential Effects of IL6 and Activin A in the Development of Cancer-Associated Cachexia. Cancer research, 2016, 09-15, Volume: 76, Issue:18 Topics: Activins; Animals; Blotting, Western; Cachexia; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Neoplasms; Polymerase Chain Reaction	2016
Baicalin supplementation reduces serum biomarkers of skeletal muscle wasting and may protect against lean body mass reduction in cancer patients: Results from a pilot open-label study. Neuro endocrinology letters, 2016, Volume: 37, Issue:3 Topics: Absorptiometry, Photon; Activins; Aged; Biomarkers; Body Weight; Cachexia; Endpoint Determination; Female; Flavonoids; Humans; Male; Middle Aged; Muscle, Skeletal; Muscular Atrophy; Neoplasms; NF-kappa B; Pilot Projects; Wasting Syndrome; Weight Loss	2016
Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival. Cell, 2010, Aug-20, Volume: 142, Issue:4 Topics: Activin Receptors, Type II; Activins; Animals; Anorexia; Atrophy; Cachexia; Female; Humans; Inhibins; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Myoblasts; Myocardium; Neoplasm Transplantation; Neoplasms; Signal Transduction; Transplantation, Heterologous; Tumor Necrosis Factor-alpha	2010
Cachexia in cancer: is it treatable at the molecular level? Journal of the National Cancer Institute, 2010, Nov-17, Volume: 102, Issue:22 Topics: Activins; Cachexia; Humans; Muscle, Skeletal; Myostatin; Neoplasms; Receptors, Androgen	2010
InACTIVatINg cancer cachexia. Disease models & mechanisms, 2011, Volume: 4, Issue:3 Topics: Activin Receptors, Type II; Activins; Animals; Cachexia; Disease Models, Animal; Humans; Mice; Muscle, Skeletal; Neoplasms; Signal Transduction; Transforming Growth Factor beta	2011
Myostatin is a novel tumoral factor that induces cancer cachexia. The Biochemical journal, 2012, Aug-15, Volume: 446, Issue:1 Topics: Activin Receptors, Type II; Activins; Animals; Autophagy; Cachexia; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Culture Media, Conditioned; Humans; Lysosomes; Mice; Mice, Inbred Strains; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts, Skeletal; Myostatin; NF-kappa B; Reactive Oxygen Species; Signal Transduction	2012
Activin-β(c) reduces reproductive tumour progression and abolishes cancer-associated cachexia in inhibin-deficient mice. The Journal of pathology, 2013, Volume: 229, Issue:4 Topics: Activins; Animals; Apoptosis; Cachexia; Cell Line; Cell Proliferation; Dimerization; Disease Progression; Female; Follistatin; Gene Expression; Humans; Inhibin-beta Subunits; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Ovarian Neoplasms; Phosphorylation; Sequence Deletion; Smad2 Protein; Testicular Neoplasms	2013
Activin induces x-zone apoptosis that inhibits luteinizing hormone-dependent adrenocortical tumor formation in inhibin-deficient mice. Molecular and cellular biology, 2003, Volume: 23, Issue:11 Topics: Activins; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Carcinoma; Animals; Apoptosis; Body Weight; Cachexia; DNA-Binding Proteins; Estradiol; Female; Humans; In Situ Hybridization; Inhibins; Luteinizing Hormone; Male; Mice; Mice, Knockout; Mice, Transgenic; Ovarian Neoplasms; Ovariectomy; Phenotype; Receptors, LH; Smad2 Protein; Testosterone; Trans-Activators	2003
Interrelationship of growth differentiation factor 9 and inhibin in early folliculogenesis and ovarian tumorigenesis in mice. Molecular endocrinology (Baltimore, Md.), 2004, Volume: 18, Issue:6 Topics: Activins; Animals; Bone Morphogenetic Protein 15; Cachexia; Cell Differentiation; Cell Proliferation; DNA-Binding Proteins; Female; Granulosa Cells; Growth Differentiation Factor 9; Homeodomain Proteins; In Situ Hybridization; Inhibins; Intercellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Mice, Transgenic; Oncogene Proteins; Ovarian Follicle; Ovarian Neoplasms; Protein Structure, Tertiary; Proto-Oncogene Proteins c-kit; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Stem Cell Factor; Steroidogenic Factor 1; Theca Cells; Time Factors; Transcription Factors; Up-Regulation; Wasting Syndrome	2004
Prevention of cachexia-like syndrome development and reduction of tumor progression in inhibin-deficient mice following administration of a chimeric activin receptor type II-murine Fc protein. Molecular human reproduction, 2007, Volume: 13, Issue:9 Topics: Activin Receptors, Type II; Activins; Animals; Cachexia; Disease Progression; Female; Follicle Stimulating Hormone; Gastric Mucosa; Immunoglobulin Fc Fragments; Immunoglobulin G; Inhibins; Liver; Male; Mice; Mice, Knockout; Recombinant Fusion Proteins; Sex Cord-Gonadal Stromal Tumors; Stomach; Syndrome; Testicular Neoplasms; Wasting Syndrome	2007
Development of cancer cachexia-like syndrome and adrenal tumors in inhibin-deficient mice. Proceedings of the National Academy of Sciences of the United States of America, 1994, Sep-13, Volume: 91, Issue:19 Topics: Activins; Adrenal Gland Neoplasms; Animals; Cachexia; Female; Inhibins; Male; Mice; Mice, Knockout; Neoplasms, Gonadal Tissue; Orchiectomy; Ovariectomy	1994
Activin signaling through activin receptor type II causes the cachexia-like symptoms in inhibin-deficient mice. Molecular endocrinology (Baltimore, Md.), 1996, Volume: 10, Issue:5 Topics: Activin Receptors; Activins; Animals; Cachexia; Female; Inhibins; Liver; Male; Mice; Mice, Mutant Strains; Oligopeptides; Ovarian Neoplasms; Peptides; Receptors, Growth Factor; Sex Cord-Gonadal Stromal Tumors; Signal Transduction; Stomach; Testicular Neoplasms; Weight Loss	1996
Role of androgens in testicular tumor development in inhibin-deficient mice. Endocrinology, 1997, Volume: 138, Issue:11 Topics: Activins; Androgen-Insensitivity Syndrome; Androgens; Animals; Cachexia; Female; Hybridization, Genetic; Inhibins; Male; Mice; Mice, Mutant Strains; Mutation; Peptides; Receptors, Androgen; Testicular Neoplasms	1997
Induction of cachexia in mice by systemically administered myostatin. Science (New York, N.Y.), 2002, May-24, Volume: 296, Issue:5572 Topics: 3T3 Cells; Activins; Adipose Tissue; Animals; Body Weight; Cachexia; CHO Cells; Cricetinae; Eating; Female; Follistatin; Liver; Mice; Mice, Nude; Muscle Fibers, Skeletal; Muscle, Skeletal; Myostatin; Organ Size; Peptide Fragments; Recombinant Proteins; Transforming Growth Factor beta; Wasting Syndrome; Weight Loss	2002