activins has been researched along with Akinetic-Rigid Variant of Huntington Disease in 3 studies
Activins: Activins are produced in the pituitary, gonads, and other tissues. By acting locally, they stimulate pituitary FSH secretion and have diverse effects on cell differentiation and embryonic development. Activins are glycoproteins that are hetero- or homodimers of INHIBIN-BETA SUBUNITS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Huntington disease is characterized by the selective loss of striatal neurons, particularly of medium-sized spiny glutamate decarboxylase67 staining/GABAergic projection neurons which co-contain the calcium binding protein calbindin." | 1.30 | Administration of recombinant human Activin-A has powerful neurotrophic effects on select striatal phenotypes in the quinolinic acid lesion model of Huntington's disease. ( Alexi, T; Clark, RG; Gluckman, PD; Hughes, PE; Williams, CE, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fjodorova, M | 2 |
| Li, M | 2 |
| Arber, C | 1 |
| Precious, SV | 1 |
| Cambray, S | 1 |
| Risner-Janiczek, JR | 1 |
| Kelly, C | 1 |
| Noakes, Z | 1 |
| Heuer, A | 1 |
| Ungless, MA | 1 |
| RodrÃguez, TA | 1 |
| Rosser, AE | 1 |
| Dunnett, SB | 1 |
| Hughes, PE | 1 |
| Alexi, T | 1 |
| Williams, CE | 1 |
| Clark, RG | 1 |
| Gluckman, PD | 1 |
3 other studies available for activins and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Robust Induction of DARPP32-Expressing GABAergic Striatal Neurons from Human Pluripotent Stem Cells.
Topics: Activins; Cell Culture Techniques; Cell Differentiation; Cell- and Tissue-Based Therapy; Corpus Stri | 2018 |
Activin A directs striatal projection neuron differentiation of human pluripotent stem cells.
Topics: Activins; Animals; Cell Differentiation; Cell Line; Cell Survival; Disease Models, Animal; Dopamine | 2015 |
Administration of recombinant human Activin-A has powerful neurotrophic effects on select striatal phenotypes in the quinolinic acid lesion model of Huntington's disease.
Topics: Activins; Animals; Calbindin 2; Choline O-Acetyltransferase; Corpus Striatum; gamma-Aminobutyric Aci | 1999 |