Page last updated: 2024-08-17

acrylamide and Encephalopathy, Toxic

acrylamide has been researched along with Encephalopathy, Toxic in 72 studies

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (18.06)29.6817
2010's32 (44.44)24.3611
2020's27 (37.50)2.80

Authors

AuthorsStudies
Hassan, DM; Welson, NN; Yassa, HD1
Deng, L; Fan, L; Lu, X; Zhao, L; Zhao, M; Zhu, Y1
Chang, CH; Chen, YR; Chen, YT; Hung, CY; Lin, TJ; Tsai, NZ; Yi, HH1
Banaś-Ząbczyk, A; Kopańska, M; Kuduk, B; Łagowska, A1
Chen, C; Fan, B; Wang, F; Zhang, W1
Arockiaraj, J; Atef Hatamleh, A; Boopathi, S; Gatasheh, MK; Gopinath, P; Guru, A; Haridevamuthu, B; Juliet, A; Manjunathan, T; Murugan, R; Ranjith Wilson Alphonse, C1
Abboud, MI; Daher, R; El-Zakhem Naous, G; Merhi, A; Mroueh, M; Taleb, RI1
Alm, IM; Andersen, JM; Dirven, H; Duale, N; Holme, JA; Lauvås, AJ; Lislien, M; Macko, P; Myhre, O; Paulsen, RE; Pistollato, F; Skarpen, E; Sørensen, V1
Chen, X; Fu, H; Gao, W; Li, B; Li, Y; Xiao, J; Yang, H; Zhang, Y1
Huang, Z; Liu, Z; Lou, J; Shan, S; Song, F; Wang, S; Yang, Y; Yong, H1
Abd-Elhakim, YM; Abd-Elsalam, MM; Abdelhamid, AE; Abduljabbar, MH; Alosaimi, ME; Alsieni, M; Dahran, N; El-Shetry, ES; Hassan, BA; Metwally, MMM; Mohamed, AA; Said, EN1
Chen, J; Gao, H; Gao, Q; Pang, Y; Xue, Y; Yang, J1
Ekuban, FA; Fergany, A; Ichihara, G; Ichihara, S; Iwakura, Y; Kimura, Y; Suzuki, A; Zong, C1
Eisvand, F; Ghasemzadeh Rahbardar, M; Ghobakhlou, F; Hosseinzadeh, H; Razavi, BM1
Admon, A; Arick, MA; Bedrossiantz, J; Ben-Lulu, S; Faria, M; Garcia-Reyero, N; Gómez-Canela, C; Gómez-Oliván, LM; Hsu, CY; Orozco, M; Prats, E; Raldúa, D; Ziv, T1
Abnous, K; Hosseinzadeh, H; Mehri, S; Tabeshpour, J2
Hu, Y; Huang, L; Li, X; Thomas, ER; Wang, W1
Foroutanfar, A; Hosseinzadeh, H; Kamyar, M; Mehri, S; Tandisehpanah, Z1
Cao, X; Guo, J; Hu, X; Li, S; Wang, J1
Abd-Elsalam, RM; Ahmed, KA; Ali, SE; Alsherbiny, MA; El Badawy, SA; Farag, OM; Li, CG; Ogaly, HA1
Abdel-Daim, MM; Abdel-Fattah, AM; Bin-Jumah, M; El-Seedi, HR; Saied, EM1
Lee, C; Lee, YJ; Sim, KH; Triningsih, D; Yang, JH1
Alexander, J; Andreassen, M; Caspersen, IH; Dirven, H; Forsby, A; Hofer, T; Husøy, T; Johansson, Y; Knutsen, HK; Lindeman, B; Myhre, O; Paulsen, RE; Vejrup, K1
Baghal, E; Ghobadi, H; Hashemidanesh, N; Khodaparast, F; Salimi, A; Seydi, E1
Abdel-Daim, MM; Almeer, R; Emam, MA; Farouk, SM; Gad, FA1
Cho, JW; Chun, HS; Kim, WK; Lee, J; Lee, S; Park, JS; Samanta, P; Yoon, S1
Davuljigari, CB; Ekuban, FA; Fergany, AAM; Ichihara, G; Morikawa, K; Zong, C1
Jacobsson, SOP; Karlsson, J; Popova, D1
Cao, P; Chen, X; Li, B; Li, ZS; Shao, H; Wang, XH; Xiao, JW; Yang, YG; Zhang, B; Zhu, D1
Moustafa, EM; Thabet, NM1
Esmaeelpanah, E; Hosseinzadeh, H; Razavi, BM; Vahdati Hasani, F1
Attoff, K; Forsby, A; Gliga, A; Lundqvist, J; Norinder, U1
Admon, A; Ben-Lulu, S; Faria, M; Gómez-Canela, C; Gómez-Oliván, LM; Novoa-Luna, KA; Piña, B; Prats, E; Raldúa, D; Tauler, R; Ziv, T1
Abboud, MI; El-Zakhem Naous, G; Merhi, A; Mroueh, M; Taleb, RI1
Hayes, AW; Hosseinzadeh, H; Karimi, G; Kianfar, M; Mehri, S; Nezami, A1
Kunnel, SG; Sahoo, I; Satapathy, P; Subramanya, S; Zameer, F1
Bedrossiantz, J; Faria, M; Gómez-Oliván, LM; Orozco, M; Porta, JM; Prats, E; Raldúa, D; Valls, A1
Hasegawa, R; Ichihara, G; Ichihara, S; Nagashima, D; Ohsako, S; Sakurai, T; Urushitani, M; Zhang, L; Zong, C1
Malaguarnera, G; Malaguarnera, M; Pennisi, M; Puglisi, V; Vacante, M; Vinciguerra, L1
Klimatskaya, LG; Kolesnikov, SI; Tarskikh, MM1
Prasad, SN3
Li, GZ; Song, FY; Xie, KQ; Yang, XW; Yi, C; Yu, SF; Zhang, CL; Zhao, XL1
Mohd Amin, MC; Pandey, M1
Hosseinzadeh, H; Mehri, S; Meshki, MA1
Chen, S; Hu, X; Song, L; Wang, J; Yan, R; Zhang, W; Zhao, S1
Adewale, OO; Brimson, JM; Gbadegesin, MA; Isidoro, C; Odunola, OA; Owumi, SE; Tencomnao, T1
Cheng, G; Guo, X; Lu, Q; Pan, X; Xiong, F; Yan, H1
Friedman, M1
E, M; Li, G; Wang, S; Wei, X; Yan, F; Yang, X; Yu, S; Zhang, C; Zhang, F1
Alsulaimani, MS; Ansar, S; El Ansary, AK; Siddiqi, NJ; Zargar, S1
Chan, HM; Chen, F; Hu, XS; Wang, FSL; Zhao, M1
Li, L; Liu, W; Shao, ML; Sun, HY; Zhao, HY1
Jilin, F; Shuming, C; Xichun, Z1
Guo, C; Li, B; Xiao, J1
Honma, M; Inoue, K; Irie, K; Koyama, N; Morikawa, T; Nishikawa, A; Shibutani, M; Takahashi, M; Yoshida, M1
Barber, DS; Gavin, T; LoPachin, RM; Zhang, L1
Gavin, T; LoPachin, RM1
Ali, MM; Handa, SS; Khanna, VK; Maurya, RR; Shukla, PK; Srimal, RC1
LoPachin, RM2
Decaprio, AP; Lopachin, RM1
Igisu, H; Kinoshita, Y1
Han, JY; Zhang, CW1
Das, S; Gavin, T; Geohagen, BC; LoPachin, RM1
Blaauboer, B; Forsby, A1
Barber, DS; LoPachin, RM; Stevens, S1
Barber, DS; Gavin, T; LoPachin, RM1
Eyer, J; Peterson, AP; Sickles, DW; Stone, JD1

Reviews

14 review(s) available for acrylamide and Encephalopathy, Toxic

ArticleYear
Acrylamide Neurotoxicity as a Possible Factor Responsible for Inflammation in the Cholinergic Nervous System.
    International journal of molecular sciences, 2022, Feb-12, Volume: 23, Issue:4

    Topics: Acetylcholine; Acetylcholinesterase; Acrylamide; Animals; Cholinergic Neurons; Humans; Neurotoxicity Syndromes; Receptors, Cholinergic

2022
Acrylamide-induced peripheral neuropathy: manifestations, mechanisms, and potential treatment modalities.
    Environmental science and pollution research international, 2021, Volume: 28, Issue:11

    Topics: Acrylamide; Animals; Cooking; Humans; Neurotoxicity Syndromes; Peripheral Nervous System Diseases; Solanum tuberosum

2021
Does the food processing contaminant acrylamide cause developmental neurotoxicity? A review and identification of knowledge gaps.
    Reproductive toxicology (Elmsford, N.Y.), 2021, Volume: 101

    Topics: Acrylamide; Animals; Dietary Exposure; Embryonic Development; Female; Food Handling; Humans; Maternal-Fetal Exchange; Neurotoxicity Syndromes; Pregnancy

2021
Acrylamide Induced Toxicity and the Propensity of Phytochemicals in Amelioration: A Review.
    Central nervous system agents in medicinal chemistry, 2019, Volume: 19, Issue:2

    Topics: Acrylamide; Animals; Cooking; Humans; Mitochondrial Diseases; Neurotoxicity Syndromes; Oxidative Stress; Phytochemicals

2019
Neurotoxicity of acrylamide in exposed workers.
    International journal of environmental research and public health, 2013, Aug-27, Volume: 10, Issue:9

    Topics: Acrylamide; Animals; Humans; Neurotoxicity Syndromes; Occupational Exposure; Risk Assessment

2013
The Potential for Plant Derivatives against Acrylamide Neurotoxicity.
    Phytotherapy research : PTR, 2015, Volume: 29, Issue:7

    Topics: Acorus; Acrylamide; Acyclic Monoterpenes; Curcuma; Disulfides; Flavonoids; Humans; Monoterpenes; Neuroprotective Agents; Neurotoxicity Syndromes; Panax; Phytochemicals; Phytotherapy; Rosmarinus; Rutin; Soy Foods; Sulfinic Acids; Zingiber officinale

2015
Acrylamide: inhibition of formation in processed food and mitigation of toxicity in cells, animals, and humans.
    Food & function, 2015, Volume: 6, Issue:6

    Topics: Acrylamide; Animals; Anticarcinogenic Agents; Antidotes; Antioxidants; Apoptosis; Carcinogens; Cooking; Fast Foods; Food Additives; Food Contamination; Food Handling; Food, Preserved; Guidelines as Topic; Hot Temperature; Humans; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Teratogens

2015
[General survey of mechanisms of acrylamide neurotoxicity].
    Wei sheng yan jiu = Journal of hygiene research, 2010, Volume: 39, Issue:3

    Topics: Acrylamide; Animals; Apoptosis; Axonal Transport; Energy Metabolism; Humans; Neurotoxicity Syndromes; Peripheral Nervous System Diseases

2010
Molecular mechanism of acrylamide neurotoxicity: lessons learned from organic chemistry.
    Environmental health perspectives, 2012, Volume: 120, Issue:12

    Topics: Acrylamide; Algorithms; Animals; Ecotoxicology; Humans; Mice; Nerve Endings; Neurotoxicity Syndromes; Proteomics; Rats; Risk Assessment

2012
The changing view of acrylamide neurotoxicity.
    Neurotoxicology, 2004, Volume: 25, Issue:4

    Topics: Acrylamide; Animals; Carcinogens; Environmental Pollutants; Humans; Neurotoxicity Syndromes

2004
Protein adduct formation as a molecular mechanism in neurotoxicity.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 86, Issue:2

    Topics: Acrylamide; Animals; Hexanones; Humans; Nerve Tissue Proteins; Neurotoxicity Syndromes; Neurotoxins; Protein Binding; Xenobiotics

2005
Acrylamide neurotoxicity: neurological, morhological and molecular endpoints in animal models.
    Advances in experimental medicine and biology, 2005, Volume: 561

    Topics: Acrylamide; Acrylamides; Animals; Cell Membrane; Chemical Industry; Cysteine; Disease Models, Animal; Electrophysiology; Humans; Muscle, Skeletal; Nerve Degeneration; Nervous System Diseases; Neurons; Neurotoxicity Syndromes; Neurotoxins; Rats; Temperature; Time Factors

2005
[Toxicity study for acrylamide].
    Wei sheng yan jiu = Journal of hygiene research, 2006, Volume: 35, Issue:4

    Topics: Acrylamide; Animals; Carcinogens; Humans; Mutagens; Neurotoxicity Syndromes

2006
Molecular mechanisms of the conjugated alpha,beta-unsaturated carbonyl derivatives: relevance to neurotoxicity and neurodegenerative diseases.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 104, Issue:2

    Topics: Acrolein; Acrylamide; Aldehydes; Alzheimer Disease; Animals; Brain; Disease Models, Animal; DNA Adducts; DNA Damage; Humans; Neurotoxicity Syndromes

2008

Other Studies

58 other study(ies) available for acrylamide and Encephalopathy, Toxic

ArticleYear
The Possible Protective Role of Dark Chocolate Against Acrylamide Neurotoxicity in Weaning Rats Cerebellum.
    Molecular neurobiology, 2022, Volume: 59, Issue:1

    Topics: Acrylamide; Animals; Cerebellum; Chocolate; Male; Neurons; Neurotoxicity Syndromes; Protective Agents; Rats; Rats, Sprague-Dawley; Weaning

2022
The involvement of oxidative stress, neuronal lesions, neurotransmission impairment, and neuroinflammation in acrylamide-induced neurotoxicity in C57/BL6 mice.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:27

    Topics: Acrylamide; Animals; Glutathione; Mice; Neuroinflammatory Diseases; Neurotoxicity Syndromes; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Synaptic Transmission

2022
AQP4 Attenuated TRAF6/NFκB Activation in Acrylamide-Induced Neurotoxicity.
    Molecules (Basel, Switzerland), 2022, Feb-04, Volume: 27, Issue:3

    Topics: Acrylamide; Animals; Aquaporin 4; Male; Neuroprotective Agents; Neurotoxicity Syndromes; NF-kappa B; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; TNF Receptor-Associated Factor 6

2022
Acrylamide causes neurotoxicity by inhibiting glycolysis and causing the accumulation of carbonyl compounds in BV2 microglial cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2022, Volume: 163

    Topics: Acrylamide; Animals; Glycolysis; Lipopolysaccharides; Mice; Microglia; Neurotoxicity Syndromes; NF-kappa B; Pyruvaldehyde

2022
Amelioration of acrylamide induced neurotoxicity by benzo[b]thiophene analogs via glutathione redox dynamics in zebrafish larvae.
    Brain research, 2022, 08-01, Volume: 1788

    Topics: Acrylamide; Animals; Antioxidants; Glutathione; Larva; Neurotoxicity Syndromes; Oxidation-Reduction; Oxidative Stress; Thiophenes; Zebrafish

2022
Carcinogenic and neurotoxic risks of acrylamide consumed through bread, kaak, toast, and crackers among the Lebanese Population.
    Regulatory toxicology and pharmacology : RTP, 2022, Volume: 132

    Topics: Acrylamide; Bread; Carcinogens; Child; Chromatography, Liquid; Food Contamination; Humans; Neurotoxicity Syndromes; Tandem Mass Spectrometry; Young Adult

2022
Developmental neurotoxicity of acrylamide and its metabolite glycidamide in a human mixed culture of neurons and astrocytes undergoing differentiation in concentrations relevant for human exposure.
    Neurotoxicology, 2022, Volume: 92

    Topics: Acrylamide; Astrocytes; Brain-Derived Neurotrophic Factor; Epoxy Compounds; Female; Humans; Induced Pluripotent Stem Cells; Infant, Newborn; Microtubule-Associated Proteins; Nestin; Neurons; Neurotoxicity Syndromes; Pregnancy; Tubulin

2022
Acrylamide-induced damage to postsynaptic plasticity is CYP2E1 dependent in an SH-SY5Y co-culture system.
    Toxicology in vitro : an international journal published in association with BIBRA, 2022, Volume: 84

    Topics: Acrylamide; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Coculture Techniques; Cytochrome P-450 CYP2E1; Humans; Neuroblastoma; Neurotoxicity Syndromes; Receptors, N-Methyl-D-Aspartate

2022
Mitochondrial dysfunction promotes the necroptosis of Purkinje cells in the cerebellum of acrylamide-exposed rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2023, Volume: 171

    Topics: Acrylamide; Animals; Cerebellum; Humans; Mitochondria; Necroptosis; Neurotoxicity Syndromes; Purkinje Cells; Rats

2023
Palliative effect of Moringa olifera-mediated zinc oxide nanoparticles against acrylamide-induced neurotoxicity in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2023, Volume: 171

    Topics: Acetylcholinesterase; Acrylamide; Animals; Catalase; Dopamine; Humans; Male; Nanoparticles; Neurotoxicity Syndromes; Oxidative Stress; Rats; Rats, Sprague-Dawley; Zinc Oxide

2023
Protective effect and mechanism of
    Food & function, 2023, May-22, Volume: 14, Issue:10

    Topics: Acrylamide; Animals; Humans; Lycium; Neuroblastoma; Neuroprotective Agents; Neurotoxicity Syndromes; NF-E2-Related Factor 2; Rats

2023
Deletion of IL-1β exacerbates acrylamide-induced neurotoxicity in mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2023, Sep-28, Volume: 195, Issue:2

    Topics: Acrylamide; Animals; Body Weight; Glutathione; Glutathione Disulfide; Humans; Interleukin-1beta; Male; Mice; Mice, Knockout; Neurotoxicity Syndromes; Oxidative Stress

2023
Evaluating the effect of alpha-mangostin on neural toxicity induced by acrylamide in rats.
    Environmental science and pollution research international, 2023, Volume: 30, Issue:42

    Topics: Acrylamide; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Glutathione; Humans; Male; Neurotoxicity Syndromes; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Vitamin E

2023
Therapeutic potential of N-acetylcysteine in acrylamide acute neurotoxicity in adult zebrafish.
    Scientific reports, 2019, 11-11, Volume: 9, Issue:1

    Topics: Acetylcysteine; Acrylamide; Acylation; Animals; Antioxidants; Blood-Brain Barrier; Cell Membrane Permeability; Free Radical Scavengers; Glutathione; Neurotoxicity Syndromes; Oxidative Stress; Proteome; Transcriptome; Zebrafish

2019
Role of Oxidative Stress, MAPKinase and Apoptosis Pathways in the Protective Effects of Thymoquinone Against Acrylamide-Induced Central Nervous System Toxicity in Rat.
    Neurochemical research, 2020, Volume: 45, Issue:2

    Topics: Acrylamide; Animals; Apoptosis; Benzoquinones; Cerebral Cortex; Glutathione; Lipid Peroxidation; Male; MAP Kinase Signaling System; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Rats

2020
Neuroprotective effects of notoginsenoside R1 by upregulating Trx-1 on acrylamide-induced neurotoxicity in PC12.
    Human & experimental toxicology, 2020, Volume: 39, Issue:6

    Topics: Acrylamide; Animals; Cell Survival; Ginsenosides; Membrane Potential, Mitochondrial; Mitochondria; Neuroprotective Agents; Neurotoxicity Syndromes; PC12 Cells; Rats; Reactive Oxygen Species; Thioredoxins; Up-Regulation

2020
Protective effect of punicalagin, the main polyphenol compound of pomegranate, against acrylamide-induced neurotoxicity and hepatotoxicity in rats.
    Phytotherapy research : PTR, 2020, Volume: 34, Issue:12

    Topics: Acrylamide; Animals; Chemical and Drug Induced Liver Injury; Fruit; Hydrolyzable Tannins; Male; Neurotoxicity Syndromes; Polyphenols; Pomegranate; Rats; Rats, Wistar

2020
The anti-apoptotic, antioxidant and anti-inflammatory effects of curcumin on acrylamide-induced neurotoxicity in rats.
    BMC pharmacology & toxicology, 2020, 08-18, Volume: 21, Issue:1

    Topics: Acrylamide; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Behavior, Animal; Brain; Curcumin; Interleukin-1beta; Male; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Rats, Sprague-Dawley; Telomerase; Tumor Necrosis Factor-alpha

2020
Metabolomic Profiling and Neuroprotective Effects of Purslane Seeds Extract Against Acrylamide Toxicity in Rat's Brain.
    Neurochemical research, 2021, Volume: 46, Issue:4

    Topics: Acrylamide; Animals; Brain; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Gene Expression; Male; Metabolomics; Neuroprotective Agents; Neurotoxicity Syndromes; Plant Extracts; Portulaca; Proto-Oncogene Proteins c-akt; Rats, Wistar; Seeds; Signal Transduction

2021
Acrylamide and its metabolite induce neurotoxicity via modulation of protein kinase C and AMP-activated protein kinase pathways.
    Toxicology in vitro : an international journal published in association with BIBRA, 2021, Volume: 72

    Topics: Acrylamide; AMP-Activated Protein Kinases; Animals; Autophagy; Cytochrome P-450 CYP2E1; Epoxy Compounds; Extracellular Signal-Regulated MAP Kinases; Neurotoxicity Syndromes; PC12 Cells; Protein Kinase C; Rats; RNA, Small Interfering

2021
Mitochondrial, lysosomal and DNA damages induced by acrylamide attenuate by ellagic acid in human lymphocyte.
    PloS one, 2021, Volume: 16, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acrylamide; Blood Donors; Cells, Cultured; DNA Damage; Ellagic Acid; Female; Glutathione; Humans; Lipid Peroxidation; Lymphocytes; Lysosomes; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria; Neurotoxicity Syndromes; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Young Adult

2021
Exploring the possible neuroprotective and antioxidant potency of lycopene against acrylamide-induced neurotoxicity in rats' brain.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 138

    Topics: Acrylamide; Administration, Oral; Animals; Antioxidants; Brain; Lycopene; Male; Neuroprotection; Neurotoxicity Syndromes; Oxidative Stress; Rats

2021
Developmental and Neurotoxicity of Acrylamide to Zebrafish.
    International journal of molecular sciences, 2021, Mar-29, Volume: 22, Issue:7

    Topics: Acrylamide; Air Sacs; Animals; Animals, Genetically Modified; Disease Models, Animal; Embryo, Nonmammalian; Embryonic Development; Neurotoxicity Syndromes; Scoliosis; Swimming; Zebrafish

2021
Nrf2 Activation Attenuates Acrylamide-Induced Neuropathy in Mice.
    International journal of molecular sciences, 2021, Jun-01, Volume: 22, Issue:11

    Topics: Acrylamide; Animals; Disease Models, Animal; Humans; Inflammation; Isothiocyanates; Mice; Microglia; Neurotoxicity Syndromes; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Signal Transduction; Sulfoxides

2021
Comparison of neurons derived from mouse P19, rat PC12 and human SH-SY5Y cells in the assessment of chemical- and toxin-induced neurotoxicity.
    BMC pharmacology & toxicology, 2017, 06-05, Volume: 18, Issue:1

    Topics: Acrylamide; Animals; Buthionine Sulfoximine; Cell Differentiation; Cell Line, Tumor; Cell Survival; Glutathione; Humans; Membrane Potential, Mitochondrial; Methylmercury Compounds; Mice; Models, Biological; Neurons; Neurotoxicity Syndromes; Okadaic Acid; Rats

2017
Acrylamide-induced Subacute Neurotoxic Effects on the Cerebral Cortex and Cerebellum at the Synapse Level in Rats.
    Biomedical and environmental sciences : BES, 2017, Volume: 30, Issue:6

    Topics: Acrylamide; Animals; Cerebellum; Cerebral Cortex; Drug Administration Schedule; Gait; Gene Expression Regulation; Male; Neurons; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Synapses; Synapsins; Synaptic Vesicles; Weight Loss

2017
Protective effect of rutin against brain injury induced by acrylamide or gamma radiation: role of PI3K/AKT/GSK-3β/NRF-2 signalling pathway.
    Archives of physiology and biochemistry, 2018, Volume: 124, Issue:2

    Topics: Acrylamide; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Brain; Dietary Supplements; Environmental Pollutants; Gamma Rays; Gene Expression Regulation; Male; MAP Kinase Signaling System; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Radiation Injuries; Radiation-Protective Agents; Rats, Sprague-Dawley; Rutin

2018
Evaluation of epigallocatechin gallate and epicatechin gallate effects on acrylamide-induced neurotoxicity in rats and cytotoxicity in PC 12 cells.
    Drug and chemical toxicology, 2018, Volume: 41, Issue:4

    Topics: Acrylamide; Animals; Catechin; Cell Survival; Cerebral Cortex; Eating; Glutathione; Lipid Peroxidation; Male; Neurotoxicity Syndromes; PC12 Cells; Rats; Rats, Wistar

2018
Whole genome microarray analysis of neural progenitor C17.2 cells during differentiation and validation of 30 neural mRNA biomarkers for estimation of developmental neurotoxicity.
    PloS one, 2017, Volume: 12, Issue:12

    Topics: Acrylamide; Animals; Biomarkers; Cell Differentiation; Cell Line; Cell Survival; Gene Expression Profiling; Gene Expression Regulation; Genome; Mannitol; Methylmercury Compounds; Mice; Microarray Analysis; Neural Stem Cells; Neurotoxicity Syndromes; Principal Component Analysis; Reproducibility of Results; RNA, Messenger; Time Factors; Valproic Acid

2017
Acrylamide acute neurotoxicity in adult zebrafish.
    Scientific reports, 2018, 05-21, Volume: 8, Issue:1

    Topics: Acrylamide; Acute Disease; Animals; Behavior, Animal; Gene Expression Regulation; Neurotoxicity Syndromes; Proteome; Transcriptome; Zebrafish; Zebrafish Proteins

2018
Carcinogenic and neurotoxic risks of acrylamide consumed through caffeinated beverages among the lebanese population.
    Chemosphere, 2018, Volume: 208

    Topics: Acrylamide; Adolescent; Adult; Aged; Beverages; Caffeine; Carcinogens; Child; Child, Preschool; Dietary Exposure; Female; Food Contamination; Humans; Lebanon; Male; Middle Aged; Neurotoxicity Syndromes; Risk Assessment; Young Adult

2018
The protective effect of fasudil against acrylamide-induced cytotoxicity in PC12 cells.
    Drug and chemical toxicology, 2020, Volume: 43, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acrylamide; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cell Survival; Cytoprotection; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species

2020
Neuroprotective Effects of Thymoquinone in Acrylamide-Induced Peripheral Nervous System Toxicity Through MAPKinase and Apoptosis Pathways in Rat.
    Neurochemical research, 2019, Volume: 44, Issue:5

    Topics: Acrylamide; Animals; Antioxidants; Glutathione; Male; Malondialdehyde; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Peripheral Nervous System; Rats, Wistar

2019
Further characterization of the zebrafish model of acrylamide acute neurotoxicity: gait abnormalities and oxidative stress.
    Scientific reports, 2019, 05-08, Volume: 9, Issue:1

    Topics: Acrylamide; Acute Disease; Animals; Behavior, Animal; Brain; Disease Models, Animal; Female; Gait; Glutathione; Male; Neurotoxicity Syndromes; Oxidative Stress; Phenotype; Software; Swimming; Zebrafish

2019
Role of microglial activation and neuroinflammation in neurotoxicity of acrylamide in vivo and in vitro.
    Archives of toxicology, 2019, Volume: 93, Issue:7

    Topics: Acrylamide; Animals; Cell Line; Cell Survival; Cerebral Cortex; Cytokines; Dose-Response Relationship, Drug; Environmental Pollutants; Inflammasomes; Inflammation; Male; Mice; Microglia; Neuroimmunomodulation; Neurotoxicity Syndromes; Rats, Wistar

2019
Pathogenesis of neurotoxicity of acrylates acrylonitrile and acrylamide: from cell to organism.
    Bulletin of experimental biology and medicine, 2013, Volume: 155, Issue:4

    Topics: Acrylamide; Acrylonitrile; Animals; Animals, Outbred Strains; Brain; Catalase; Environmental Pollutants; Humans; Lethal Dose 50; Lipid Peroxidation; Male; Malondialdehyde; Neurotoxicity Syndromes; Occupational Exposure; Rats; Reactive Oxygen Species

2013
Neuroprotective effect of geraniol and curcumin in an acrylamide model of neurotoxicity in Drosophila melanogaster: relevance to neuropathy.
    Journal of insect physiology, 2014, Volume: 60

    Topics: Acetylcholinesterase; Acrylamide; Acyclic Monoterpenes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Citrate (si)-Synthase; Curcumin; Dopamine; Drosophila melanogaster; Drug Evaluation, Preclinical; Glutathione; Locomotion; Male; Mitochondrial Diseases; Neurotoxicity Syndromes; Oxidative Stress; Phytotherapy; Succinate Dehydrogenase; Sulfhydryl Compounds; Terpenes

2014
Acrylamide alters cytoskeletal protein level in rat serum.
    Biomedical and environmental sciences : BES, 2013, Volume: 26, Issue:11

    Topics: Acrylamide; Animals; Behavior, Animal; Blotting, Western; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gait Ataxia; Male; Motor Activity; Neurotoxicity Syndromes; Rats; Rats, Wistar

2013
CNS neurotoxicity of bacterial cellulose-poly(acrylamide-sodium acrylate) hydrogel: a future therapeutic carrier.
    CNS neuroscience & therapeutics, 2014, Volume: 20, Issue:4

    Topics: Acrylamide; Animals; Bacteria; Brain; Cell Line; Cellulose; Cricetulus; Drug Carriers; Female; Fibroblasts; Hydrogels; Materials Testing; Mice; Mice, Inbred ICR; Neurotoxicity Syndromes

2014
Linalool as a neuroprotective agent against acrylamide-induced neurotoxicity in Wistar rats.
    Drug and chemical toxicology, 2015, Volume: 38, Issue:2

    Topics: Acrylamide; Acyclic Monoterpenes; Animals; Antioxidants; Cerebral Cortex; Dose-Response Relationship, Drug; Gait; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Monoterpenes; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Rats; Rats, Wistar

2015
Effective suppression of acrylamide neurotoxicity by lithium in mouse.
    Neurochemical research, 2014, Volume: 39, Issue:11

    Topics: Acrylamide; Animals; Behavior, Animal; Disease Models, Animal; Hippocampus; Lithium; Male; Mice; Neurogenesis; Neurotoxicity Syndromes; Oxidative Stress

2014
Mitigation of acrylamide-induced behavioral deficits, oxidative impairments and neurotoxicity by oral supplements of geraniol (a monoterpene) in a rat model.
    Chemico-biological interactions, 2014, Nov-05, Volume: 223

    Topics: Acrylamide; Acyclic Monoterpenes; Administration, Oral; Animals; Antioxidants; Behavior, Animal; Brain; Curcumin; Disease Models, Animal; Humans; Male; Mitochondria; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Rats; Rats, Wistar; Sciatic Nerve; Terpenes

2014
Acrylamide increases dopamine levels by affecting dopamine transport and metabolism related genes in the striatal dopaminergic system.
    Toxicology letters, 2015, Jul-02, Volume: 236, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acrylamide; Administration, Oral; Animals; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Dose-Response Relationship, Drug; Food Contamination; Gene Expression Regulation; Homovanillic Acid; Male; Nerve Tissue Proteins; Neurotoxicity Syndromes; Random Allocation; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation; Vesicular Monoamine Transport Proteins

2015
Neuroprotective Effect of Calpeptin on Acrylamide-Induced Neuropathy in Rats.
    Neurochemical research, 2015, Volume: 40, Issue:11

    Topics: Acrylamide; Animals; Behavior, Animal; Calpain; Cysteine Proteinase Inhibitors; Dipeptides; Female; Gait Disorders, Neurologic; Injections, Intraperitoneal; Neurofilament Proteins; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; Rats, Wistar; Spinal Cord

2015
Therapeutic role of quercetin on oxidative damage induced by acrylamide in rat brain.
    Pharmaceutical biology, 2016, Volume: 54, Issue:9

    Topics: Acrylamide; Animals; Antioxidants; Brain; Cytoprotection; Disease Models, Animal; Dopamine; Female; Guanosine; Interferon-gamma; Male; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Quercetin; Rats, Wistar; Serotonin

2016
Effect of acrylamide-induced neurotoxicity in a primary astrocytes/microglial co-culture model.
    Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 39

    Topics: Acrylamide; Animals; Astrocytes; Cell Survival; Coculture Techniques; Cytokines; Glutathione; Glutathione Disulfide; Mice, Inbred BALB C; Microglia; Neurotoxicity Syndromes; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress

2017
Silymarin protects against acrylamide-induced neurotoxicity via Nrf2 signalling in PC12 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 102

    Topics: Acrylamide; Animals; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Glutathione Peroxidase; Malondialdehyde; Neurotoxicity Syndromes; NF-E2-Related Factor 2; PC12 Cells; Rats; Reactive Oxygen Species; Silymarin

2017
The moderating role of dark soy sauce to acrylamide-induced oxidative stress and neurophysiological perturbations in rats.
    Toxicology mechanisms and methods, 2009, Volume: 19, Issue:6-7

    Topics: Acrylamide; Animals; Behavior, Animal; Brain; Brain Chemistry; Creatine Kinase; Epinephrine; Female; Humans; L-Lactate Dehydrogenase; Lipid Peroxidation; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Rats; Rats, Sprague-Dawley; Serotonin; Soy Foods

2009
Life stage-related differences in susceptibility to acrylamide-induced neural and testicular toxicity.
    Archives of toxicology, 2011, Volume: 85, Issue:9

    Topics: Acrylamide; Aging; Animals; Body Weight; Cerebellum; Comet Assay; Dose-Response Relationship, Drug; Glutathione; Glutathione Transferase; Immunohistochemistry; Liver; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Testis; Trigeminal Ganglion

2011
Role of the Nrf2-ARE pathway in acrylamide neurotoxicity.
    Toxicology letters, 2011, Aug-10, Volume: 205, Issue:1

    Topics: Acrylamide; Animals; Antioxidants; Blotting, Western; Brain; Cell Separation; Centrifugation; Electrophoresis, Polyacrylamide Gel; Hepatocytes; Nerve Endings; Neurotoxicity Syndromes; NF-E2-Related Factor 2; Proteins; Rats; Rats, Sprague-Dawley; Response Elements; Signal Transduction; Synaptosomes

2011
Evidence of acrylamide induced oxidative stress and neurotoxicity in Drosophila melanogaster - its amelioration with spice active enrichment: relevance to neuropathy.
    Neurotoxicology, 2012, Volume: 33, Issue:5

    Topics: Acetylcholinesterase; Acrylamide; Adenosine Triphosphate; Analysis of Variance; Animals; Antioxidants; Disease Models, Animal; Drosophila melanogaster; Environment; Eugenol; Glutathione; Lipid Peroxidation; Male; Multienzyme Complexes; Neurotoxicity Syndromes; Oxidative Stress; Protein Carbonylation; Reactive Oxygen Species; Spices; Succinate Dehydrogenase

2012
Protective effect of acorus calamus against acrylamide induced neurotoxicity.
    Phytotherapy research : PTR, 2002, Volume: 16, Issue:3

    Topics: Acorus; Acrylamide; Animals; Behavior, Animal; Corpus Striatum; Glutathione; Glutathione Transferase; Hindlimb; Male; Motor Activity; Neurotoxicity Syndromes; Paralysis; Phytotherapy; Plant Extracts; Protective Agents; Rats; Rats, Wistar; Receptors, Dopamine; Rhizome

2002
NTP-CERHR monograph on the potential human reproductive and developmental effects of acrylamide.
    NTP CERHR MON, 2005, Issue:14

    Topics: Acrylamide; Animals; Female; Fetus; Humans; Male; Neoplasms; Neurotoxicity Syndromes; Pregnancy; Reproduction

2005
Magnetic resonance for evaluation of toxic encephalopathies: implications from animal experiments.
    Neurotoxicology, 2007, Volume: 28, Issue:2

    Topics: Acrylamide; Adenosine Triphosphate; Animals; Aspartate Aminotransferases; Brain; Creatine Kinase; Enzyme Inhibitors; Ethylene Oxide; Hexachlorophene; Humans; Hydrocarbons, Brominated; L-Lactate Dehydrogenase; Magnetic Resonance Imaging; Male; Mice; Neurotoxicity Syndromes; Rats; Rats, Wistar; Risk Assessment; Spectrophotometry; Time Factors

2007
Neurotoxic mechanisms of electrophilic type-2 alkenes: soft soft interactions described by quantum mechanical parameters.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 98, Issue:2

    Topics: 1-Propanol; Acrolein; Acrylamide; Acrylates; Alkenes; Animals; Butanones; Corpus Striatum; Cysteine; Dopamine; Ethylmaleimide; Male; Neurotoxicity Syndromes; Propanols; Quantum Theory; Rats; Rats, Sprague-Dawley; Synaptosomes

2007
Integration of in vitro neurotoxicity data with biokinetic modelling for the estimation of in vivo neurotoxicity.
    Human & experimental toxicology, 2007, Volume: 26, Issue:4

    Topics: Acrylamide; Animals; Anticonvulsants; Brain Neoplasms; Caffeine; Calcium Channels; Central Nervous System Stimulants; Diazepam; Endpoint Determination; Humans; Hypnotics and Sedatives; Kinetics; Lethal Dose 50; Models, Statistical; Nerve Tissue Proteins; Neuroblastoma; Neurotoxicity Syndromes; Pesticides; Phenytoin; Rats; Xenobiotics

2007
Proteomic analysis of rat striatal synaptosomes during acrylamide intoxication at a low dose rate.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 100, Issue:1

    Topics: Acrylamide; Animals; Basal Ganglia; Body Weight; Chromatography, Liquid; Cysteine; Gait; Isotope Labeling; Male; Nerve Tissue Proteins; Neurotoxicity Syndromes; Proteomics; Rats; Rats, Sprague-Dawley; Synaptosomes; Tandem Mass Spectrometry; Time Factors

2007
Neurofilaments are non-essential elements of toxicant-induced reductions in fast axonal transport: pulse labeling in CNS neurons.
    Neurotoxicology, 2000, Volume: 21, Issue:4

    Topics: Acrylamide; Animals; Axonal Transport; Central Nervous System; Hexanones; Kinetics; Male; Mice; Mice, Transgenic; Neurofilament Proteins; Neurons; Neurotoxicity Syndromes; Neurotoxins

2000