Page last updated: 2024-08-18

acrolein and Spinal Cord Injuries

acrolein has been researched along with Spinal Cord Injuries in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (33.33)29.6817
2010's11 (52.38)24.3611
2020's3 (14.29)2.80

Authors

AuthorsStudies
Gardeen, SS; Herr, SA; Low, PS; Shi, R1
Fan, Z; Qi, C; Quan, X; Wang, X; Wu, S; Wu, T; Yu, C; Zhang, H1
Guo, K; Ma, T; Qi, CC; Quan, X; Song, BQ; Wang, H; Yu, CY1
Acosta, G; Butler, B; Shi, R1
Acosta, G; Ambaw, A; Herr, SA; Hubers, SA; Liu, F; Pond, A; Rochet, JC; Shi, R; Strathearn, KE; Tambe, MA; Tang, J; Truong, A; Walls, E; Zheng, L1
Cooper, B; Jannasch, A; Park, J; Shi, R; Tully, M; Walls, M; Zheng, L1
Allette, YM; Due, MR; Park, J; Shi, R; Walls, M; White, FA; Zheng, L1
Duerstock, B; Marquis, A; Ouyang, Z; Park, J; Pond, A; Shi, R; Vega-Alvarez, S; Walls, M; Wang, H; Zheng, L1
Shi, R; Tully, M; Zheng, L1
Acosta, G; Cao, P; Chen, Z; Muratori, B; Park, J; Shi, R; Vega-Alvarez, S; Zheng, L1
Brenia, J; Deng, LX; Gianaris, A; Gianaris, T; Goetz, M; Liu, NK; Lu, QB; Oakes, E; Ruan, Y; Shi, R; Vega-Alvarez, S; Wang, XF; Xu, XM1
Shi, R; Tian, R1
Durkes, A; Hamann, K; Ouyang, H; Pond, A; Shi, R; Uchida, K1
Hamann, K; Shi, R1
Andrade, EL; Bento, AF; Calixto, JB; Dias, MA; Forner, S; Koepp, J; Leal, PC; Leite, DF1
Rickett, T; Shi, R; Sun, W1
Luo, J; Shi, R1
Luo, J; Shi, R; Uchida, K1
Chen, WQ; John, JP; Lubec, G; Petter-Puchner, A; Pintsov, O; Pollak, A; Redl, H1
Duerstock, B; Hamann, K; Nehrt, G; Ouyang, H; Shi, R1
Burcham, PC; Kaminskas, LM; Pyke, SM; Tan, D1

Reviews

4 review(s) available for acrolein and Spinal Cord Injuries

ArticleYear
Acrolein detection: potential theranostic utility in multiple sclerosis and spinal cord injury.
    Expert review of neurotherapeutics, 2014, Volume: 14, Issue:6

    Topics: Acrolein; Humans; Lipid Peroxidation; Multiple Sclerosis; Oxidative Stress; Spinal Cord Injuries

2014
Acrolein scavenging: a potential novel mechanism of attenuating oxidative stress following spinal cord injury.
    Journal of neurochemistry, 2009, Volume: 111, Issue:6

    Topics: Acrolein; Animals; Free Radical Scavengers; Humans; Hydralazine; Lipid Peroxidation; Models, Biological; Oxidative Stress; Spinal Cord Injuries

2009
Acrolein-mediated injury in nervous system trauma and diseases.
    Molecular nutrition & food research, 2011, Volume: 55, Issue:9

    Topics: Acrolein; Animals; Central Nervous System; Humans; Mitochondria; Multiple Sclerosis; Myelin Sheath; Spinal Cord Injuries; Trauma, Nervous System

2011
Carbonyl-scavenging drugs & protection against carbonyl stress-associated cell injury.
    Mini reviews in medicinal chemistry, 2008, Volume: 8, Issue:4

    Topics: Acrolein; Alzheimer Disease; Animals; Atherosclerosis; Cell Death; Free Radical Scavengers; Humans; Hydralazine; Liver Diseases, Alcoholic; Oxidative Stress; Protective Agents; Spinal Cord Injuries

2008

Other Studies

17 other study(ies) available for acrolein and Spinal Cord Injuries

ArticleYear
Targeted delivery of acrolein scavenger hydralazine in spinal cord injury using folate-linker-drug conjugation.
    Free radical biology & medicine, 2022, 05-01, Volume: 184

    Topics: Acrolein; Animals; Folic Acid; Humans; Hydralazine; Lipid Peroxidation; Rats; Spinal Cord Injuries

2022
Hydralazine plays an immunomodulation role of pro-regeneration in a mouse model of spinal cord injury.
    Experimental neurology, 2023, Volume: 363

    Topics: Acrolein; Animals; Hydralazine; Macrophages; Male; Mice; Pain; Rats; Spinal Cord; Spinal Cord Injuries

2023
Hydralazine Promotes Central Nervous System Recovery after Spinal Cord Injury by Suppressing Oxidative Stress and Inflammation through Macrophage Regulation.
    Current medical science, 2023, Volume: 43, Issue:4

    Topics: Acrolein; Animals; Hydralazine; Inflammation; Macrophages; Mice; Neuralgia; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2023
Exogenous Acrolein intensifies sensory hypersensitivity after spinal cord injury in rat.
    Journal of the neurological sciences, 2017, Aug-15, Volume: 379

    Topics: Acrolein; Administration, Inhalation; Animals; Hyperalgesia; Male; Neuralgia; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tobacco Smoke Pollution

2017
Acrolein-mediated neuronal cell death and alpha-synuclein aggregation: Implications for Parkinson's disease.
    Molecular and cellular neurosciences, 2018, Volume: 88

    Topics: Acrolein; alpha-Synuclein; Animals; Cell Death; Cell Line; Dopamine; Dopaminergic Neurons; Oxidative Stress; Parkinson Disease; Rats; Spinal Cord Injuries; Substantia Nigra

2018
Determination of urine 3-HPMA, a stable acrolein metabolite in a rat model of spinal cord injury.
    Journal of neurotrauma, 2013, Aug-01, Volume: 30, Issue:15

    Topics: Acetylcysteine; Acrolein; Animals; Biomarkers; Chromatography, Liquid; Disease Models, Animal; Immunoblotting; Male; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tandem Mass Spectrometry

2013
Acrolein involvement in sensory and behavioral hypersensitivity following spinal cord injury in the rat.
    Journal of neurochemistry, 2014, Volume: 128, Issue:5

    Topics: Acrolein; Animals; Behavior, Animal; Blotting, Western; Cold Temperature; DNA, Complementary; Electrophysiological Phenomena; Ganglia, Sensory; Hot Temperature; Hydralazine; Inflammation; Injections, Spinal; Lipid Peroxidation; Male; Neuralgia; Nociceptors; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reflex, Abnormal; RNA; Spinal Cord Injuries; TRPA1 Cation Channel; TRPC Cation Channels

2014
Neuroprotective role of hydralazine in rat spinal cord injury-attenuation of acrolein-mediated damage.
    Journal of neurochemistry, 2014, Volume: 129, Issue:2

    Topics: Acrolein; Animals; Behavior, Animal; Blotting, Western; Contusions; Hydralazine; Locomotion; Male; Neuralgia; Neuroprotective Agents; Pain Measurement; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries

2014
Acrolein contributes to TRPA1 up-regulation in peripheral and central sensory hypersensitivity following spinal cord injury.
    Journal of neurochemistry, 2015, Volume: 135, Issue:5

    Topics: Acetylcysteine; Acrolein; Animals; Disease Models, Animal; Ganglia, Spinal; Hydralazine; Hyperalgesia; Locomotion; Male; Neuralgia; Pain Threshold; Rats; Rats, Sprague-Dawley; Skin; Spinal Cord; Spinal Cord Injuries; TRPA1 Cation Channel; TRPC Cation Channels; Up-Regulation; Vasodilator Agents

2015
Unilateral microinjection of acrolein into thoracic spinal cord produces acute and chronic injury and functional deficits.
    Neuroscience, 2016, 06-21, Volume: 326

    Topics: Acrolein; Animals; Astrocytes; Axons; Dose-Response Relationship, Drug; Female; Locomotion; Myelin Sheath; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2016
Dimercaprol is an acrolein scavenger that mitigates acrolein-mediated PC-12 cells toxicity and reduces acrolein in rat following spinal cord injury.
    Journal of neurochemistry, 2017, Volume: 141, Issue:5

    Topics: Acrolein; Animals; Body Weight; Cell Death; Dimercaprol; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Free Radical Scavengers; L-Lactate Dehydrogenase; Magnetic Resonance Spectroscopy; Male; PC12 Cells; Rats; Spinal Cord; Spinal Cord Injuries

2017
Critical role of acrolein in secondary injury following ex vivo spinal cord trauma.
    Journal of neurochemistry, 2008, Volume: 107, Issue:3

    Topics: Acrolein; Animals; Cell Membrane Permeability; Guinea Pigs; Immunoblotting; Immunohistochemistry; L-Lactate Dehydrogenase; Lysine; Spinal Cord Injuries; Superoxides

2008
TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury.
    American journal of physiology. Renal physiology, 2011, Volume: 300, Issue:5

    Topics: Acetanilides; Acrolein; Animals; Ankyrins; Calcium Channels; Capsaicin; Carbachol; Disease Models, Animal; Ganglia, Spinal; Muscle Contraction; Oligonucleotides, Antisense; Purines; Rats; RNA, Messenger; Spinal Cord; Spinal Cord Injuries; TRPA1 Cation Channel; TRPC Cation Channels; Urinary Bladder; Urinary Bladder, Overactive; Urodynamics

2011
Acrolein induces axolemmal disruption, oxidative stress, and mitochondrial impairment in spinal cord tissue.
    Neurochemistry international, 2004, Volume: 44, Issue:7

    Topics: Acrolein; Animals; Antioxidants; Axons; Cell Membrane; Ethidium; Female; Fluorescent Dyes; Guinea Pigs; Horseradish Peroxidase; L-Lactate Dehydrogenase; Lipid Peroxidation; Mitochondria; Oxidative Stress; Spinal Cord; Spinal Cord Injuries; Synaptosomes; Tetrazolium Salts; Thiazoles

2004
Accumulation of acrolein-protein adducts after traumatic spinal cord injury.
    Neurochemical research, 2005, Volume: 30, Issue:3

    Topics: Acrolein; Aldehydes; Animals; Blotting, Western; Densitometry; Female; Guinea Pigs; Immunohistochemistry; Lipid Peroxidation; Protein Binding; Proteins; Spinal Cord Injuries

2005
Nitric oxide and oxygen radical attack on GDP-dissociation inhibitor 2 (GDI-2) in spinal cord injury of the rat.
    Journal of proteome research, 2007, Volume: 6, Issue:4

    Topics: Acrolein; Amino Acid Sequence; Animals; Guanine Nucleotide Dissociation Inhibitors; Lipid Peroxidation; Male; Molecular Sequence Data; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spinal Cord Injuries; Tyrosine

2007
Hydralazine inhibits compression and acrolein-mediated injuries in ex vivo spinal cord.
    Journal of neurochemistry, 2008, Volume: 104, Issue:3

    Topics: Acrolein; Analysis of Variance; Animals; Antihypertensive Agents; Dextrans; Drug Interactions; Glutathione; Guinea Pigs; Hydralazine; In Vitro Techniques; L-Lactate Dehydrogenase; Neural Conduction; Rhodamines; Spinal Cord Injuries; Superoxides; Tetrazolium Salts; Thiazoles

2008