acrolein has been researched along with Pulmonary Disease, Chronic Obstructive in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 12 (52.17) | 24.3611 |
| 2020's | 5 (21.74) | 2.80 |
| Authors | Studies |
|---|---|
| Baraldi, PG; Geppetti, P; Materazzi, S; Preti, D | 1 |
| Kodavanti, UP; Leermakers, PA; Opperhuizen, A; Remels, AHV; Snow, SJ; Tulen, CBM; van Schooten, FJ | 1 |
| Cha, H; Chen, Y; Cho, AE; Crowley, L; Eun Moon, J; Han Chang, M; Hee Jo, E; Hee Lee, S; Hoon Pan, J; Hyun Park, J; Hyup Lee, J; Jin Lim, Y; Kim, HW; Kyeom Kim, J; Le, B; Li, Y; Nukhet, AB; Pil Pack, S; Rae Cho, Y; Zhao, J; Zhong, Y | 1 |
| Cremers, JWJM; Dentener, MA; Duistermaat, E; Fokkens, PHB; Gremmer, ER; Jessen, PJJ; Klerx, WNM; Kloosterboer, N; Koene, EJC; Maas, L; Opperhuizen, A; Remels, AHV; Staal, YCM; Tulen, CBM; van Schooten, FJ; Weibolt, N | 1 |
| Opperhuizen, A; Remels, AHV; Tulen, CBM; van Schooten, FJ | 1 |
| Hikisz, P; Jacenik, D | 1 |
| Bryant, M; Cao, X; Davis, K; Healy, SM; Muskhelishvili, L; Rosenfeldt, H; Shemansky, JM; Wu, Q; Xiong, R | 1 |
| Droma, Y; Hanaoka, M; Imamura, H; Ito, M; Kawakubo, M; Kitaguchi, Y; Yasuo, M | 1 |
| Accurso, FJ; Blalock, JE; Bowen, LE; Boydston, JA; Clancy, JP; Courville, CA; Dransfield, MT; Fortenberry, JA; Jackson, PL; Jones, CW; Liu, B; McNicholas, CM; Raju, SV; Rowe, SM; Sabbatini, G; Sloane, PA; Tang, LP; Tidwell, S | 1 |
| Crystal, RG | 1 |
| Bast, A; Bouwman, FG; Haenen, GR; Randall, MJ; van der Vliet, A | 1 |
| Blumental-Perry, A; Gao, XH; Kenche, H; Richards, DM; Tew, KD; Townsend, DM; Vedagiri, K; Ye, ZW | 1 |
| Atkinson, JJ; Borchers, MT; Deshmukh, HS; Di, PY; Dietsch, M; Hardie, WD; Korfhagen, TR; Leikauf, GD; Liu, Y; McLachlan, A; Wesselkamper, SC | 1 |
| Aldini, G; Andrè, E; Azzari, C; Carini, M; Carnini, C; Cerbai, E; Civelli, M; Geppetti, P; Massi, D; Materazzi, S; McGarvey, L; Nassini, R; Patacchini, R; Pedretti, P; Preti, D; Sadofsky, L; Sartiani, L; Stokesberry, S; Trevisan, G; Trevisani, M; Villetti, G | 1 |
| Bein, K; Leikauf, GD | 1 |
| Hanaoka, M; Kitaguchi, Y; Kraskauskas, D; Natarajan, R; Taraseviciene-Stewart, L; Voelkel, NF | 1 |
| Facchinetti, F; Moretto, N; Pastore, F; Volpi, G | 1 |
| Bertolini, S; Facchinetti, F; Iadicicco, C; Kaur, M; Marchini, G; Moretto, N; Patacchini, R; Singh, D; Volpi, G | 1 |
| Calvez, R; Ffoulkes-Jones, C; Kirkham, PA; Spooner, G | 1 |
| Beckman, E; Borchers, MT; Deshmukh, H; Harris, NL; Leikauf, GD; Tichelaar, JW; Vitucci, M; Wesselkamper, SC | 1 |
| Borchers, MT; Case, LM; Corradi, M; Deshmukh, HS; Dietsch, M; Hardie, WD; Korfhagen, TR; Leikauf, GD; Nadel, JA; Shaver, C; Wesselkamper, SC | 1 |
| Kohyama, T; Liu, X; Rennard, SI; Romberger, DJ; Sköld, CM; Spurzem, JR; Umino, T; Wang, H; Zhu, Y | 1 |
| Borchers, MT; Leikauf, GD; Prows, DR; Simpson, LG | 1 |
6 review(s) available for acrolein and Pulmonary Disease, Chronic Obstructive
| Article | Year |
|---|---|
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Peripheral Nervous System Diseases; Pulmonary Disease, Chronic Obstructive; Transient Receptor Potential Channels | 2010 |
Disruption of the Molecular Regulation of Mitochondrial Metabolism in Airway and Lung Epithelial Cells by Cigarette Smoke: Are Aldehydes the Culprit?
Topics: Acetaldehyde; Acrolein; Aldehydes; Cigarette Smoking; Epithelial Cells; Formaldehyde; Lung; Mitochondria; Nicotiana; Pulmonary Disease, Chronic Obstructive | 2023 |
The Tobacco Smoke Component, Acrolein, as a Major Culprit in Lung Diseases and Respiratory Cancers: Molecular Mechanisms of Acrolein Cytotoxic Activity.
Topics: Acrolein; Electronic Nicotine Delivery Systems; Humans; Lung; Neoplasms; Pulmonary Disease, Chronic Obstructive; Tobacco Smoke Pollution | 2023 |
Acrolein - a pulmonary hazard.
Topics: Acrolein; Animals; Apoptosis; Asthma; Bronchitis; Cooking; DNA Adducts; Gene Expression Regulation; Humans; Lung Neoplasms; Pulmonary Disease, Chronic Obstructive; Toxicity Tests, Acute; Tumor Suppressor Protein p53 | 2011 |
Acrolein effects in pulmonary cells: relevance to chronic obstructive pulmonary disease.
Topics: Acrolein; Air Pollutants; Animals; Humans; Inflammation; Lung; Models, Biological; Pulmonary Disease, Chronic Obstructive; Tobacco Smoke Pollution | 2012 |
Mucin apoprotein expression in COPD.
Topics: Acrolein; Animals; Gene Expression Regulation; Genetic Predisposition to Disease; Humans; Mice; Mucins; Mucus; Pulmonary Disease, Chronic Obstructive; Rats; Respiratory Mucosa | 2002 |
1 trial(s) available for acrolein and Pulmonary Disease, Chronic Obstructive
| Article | Year |
|---|---|
Cigarette smoke and its component acrolein augment IL-8/CXCL8 mRNA stability via p38 MAPK/MK2 signaling in human pulmonary cells.
Topics: Acrolein; Bronchi; Cells, Cultured; Chemotaxis; Dactinomycin; Epithelial Cells; Female; Humans; Interleukin-8; Intracellular Signaling Peptides and Proteins; Male; MAP Kinase Signaling System; Middle Aged; Myocytes, Smooth Muscle; Neutrophil Activation; Neutrophils; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Pneumonia; Protein Serine-Threonine Kinases; Pulmonary Disease, Chronic Obstructive; Respiratory Mucosa; RNA Stability; RNA, Messenger; Tobacco Smoke Pollution | 2012 |
16 other study(ies) available for acrolein and Pulmonary Disease, Chronic Obstructive
| Article | Year |
|---|---|
Acrolein inhalation acutely affects the regulation of mitochondrial metabolism in rat lung.
Topics: Acrolein; Administration, Inhalation; Aldehydes; Animals; Lung; Mitochondria; Nicotiana; Pulmonary Disease, Chronic Obstructive; Rats | 2022 |
Sensitization of GSH synthesis by curcumin curtails acrolein-induced alveolar epithelial apoptosis via Keap1 cysteine conjugation: A randomized controlled trial and experimental animal model of pneumonitis.
Topics: Acrolein; Air Pollutants; Animals; Apoptosis; Body Weight; Curcumin; Cysteine; Cytokines; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Inbred C57BL; Models, Animal; NF-E2-Related Factor 2; Pneumonia; Pulmonary Disease, Chronic Obstructive | 2023 |
Smoking-Associated Exposure of Human Primary Bronchial Epithelial Cells to Aldehydes: Impact on Molecular Mechanisms Controlling Mitochondrial Content and Function.
Topics: Acetaldehyde; Acrolein; Aldehydes; Epithelial Cells; Formaldehyde; Humans; Mitochondria; Nicotiana; Pulmonary Disease, Chronic Obstructive; RNA, Messenger; Smoking | 2022 |
Evaluating Mode of Action of Acrolein Toxicity in an In Vitro Human Airway Tissue Model.
Topics: Acrolein; Apoptosis; Asthma; Cell Survival; Cells, Cultured; Cigarette Smoking; Epithelial Cells; Glutathione; Glutathione Disulfide; Heme Oxygenase-1; Humans; Inhalation Exposure; Lung; Mucin-1; Nicotiana; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Respiratory System; Smoke | 2018 |
The relationship between acrolein and oxidative stress in COPD: in systemic plasma and in local lung tissue.
Topics: Acrolein; Aged; Biomarkers; Case-Control Studies; Female; Humans; Lung; Male; Non-Smokers; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Smokers; Smoking | 2019 |
Cigarette smoke induces systemic defects in cystic fibrosis transmembrane conductance regulator function.
Topics: Acrolein; Aged; Animals; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Exercise Tolerance; Female; Humans; Intestinal Mucosa; Male; Mice; Middle Aged; Nasal Mucosa; Pulmonary Disease, Chronic Obstructive; Smoking; Sodium; Spirometry; Sweat | 2013 |
Are the smoking-induced diseases an acquired form of cystic fibrosis?
Topics: Acrolein; Animals; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Humans; Male; Pulmonary Disease, Chronic Obstructive; Smoking; Sweat | 2013 |
The tobacco smoke component acrolein induces glucocorticoid resistant gene expression via inhibition of histone deacetylase.
Topics: Acrolein; Cell Line, Tumor; Cells, Cultured; Drug Resistance; Gene Expression; Glucocorticoids; Glutathione; Histone Deacetylase 2; Humans; Hydrocortisone; Inflammation; Interleukin-8; Lipopolysaccharides; Lung; Macrophages; Pulmonary Disease, Chronic Obstructive; RNA, Messenger; Smoking; Tumor Necrosis Factor-alpha; Up-Regulation | 2016 |
Adverse Outcomes Associated with Cigarette Smoke Radicals Related to Damage to Protein-disulfide Isomerase.
Topics: Acrolein; Animals; Atmosphere Exposure Chambers; Cell Line; Cell Survival; Enzyme Induction; Female; Free Radicals; Humans; Hydrogen Peroxide; Hydroxylation; Lung; Mice, Inbred C57BL; Oxidation-Reduction; Peroxynitrous Acid; Protein Conformation; Protein Disulfide-Isomerases; Pulmonary Disease, Chronic Obstructive; Quinones; Respiratory Mucosa; Smoking; Unfolded Protein Response | 2016 |
Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production.
Topics: Acrolein; Animals; Enzyme Activation; Epithelial Cells; Erlotinib Hydrochloride; Gene Expression Regulation, Enzymologic; Humans; Lung; Matrix Metalloproteinase 14; Mice; Mucins; Protein Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Quinazolines; Respiratory Mucosa | 2009 |
Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents.
Topics: Acetaminophen; Acrolein; Analgesics, Non-Narcotic; Animals; Asthma; Benzoquinones; Bronchoalveolar Lavage; Calcium; Cell Line; Chromatography, Liquid; Guinea Pigs; Humans; Imines; Immunohistochemistry; Male; Mice; Pulmonary Disease, Chronic Obstructive; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2010 |
Acrolein induces endoplasmic reticulum stress and causes airspace enlargement.
Topics: Acrolein; Animals; Caspase 3; Endoplasmic Reticulum Stress; Gene Expression; Lung; Male; Protein Binding; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Rats; Rats, Sprague-Dawley; Unfolded Protein Response; Vascular Endothelial Growth Factor A | 2012 |
Cigarette smoke triggers macrophage adhesion and activation: role of lipid peroxidation products and scavenger receptor.
Topics: Acrolein; Animals; Cell Adhesion; Chemotaxis; Humans; Inflammation; Lipid Peroxidation; Macrophages, Alveolar; Mice; Nicotiana; Oxidative Stress; Plants, Toxic; Proteins; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Receptors, Immunologic; Receptors, Scavenger; Smoke; Smoking | 2003 |
CD8+ T cells contribute to macrophage accumulation and airspace enlargement following repeated irritant exposure.
Topics: Acrolein; Animals; Bronchoalveolar Lavage Fluid; CD8 Antigens; CD8-Positive T-Lymphocytes; Cytokines; Humans; Irritants; Lung; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Pulmonary Disease, Chronic Obstructive; Smoking; T-Lymphocyte Subsets | 2007 |
Acrolein-activated matrix metalloproteinase 9 contributes to persistent mucin production.
Topics: Acrolein; Animals; Enzyme Activation; ErbB Receptors; Gene Expression Regulation, Enzymologic; Humans; Lung; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mucin 5AC; Mucins; Pulmonary Disease, Chronic Obstructive; RNA, Messenger; Sputum; Tissue Inhibitor of Metalloproteinase-3 | 2008 |
Cigarette smoke inhibits human bronchial epithelial cell repair processes.
Topics: Acetaldehyde; Acrolein; Bronchi; Cell Division; Chemical Fractionation; Chemotaxis; Collagen; Epithelial Cells; Extracellular Matrix; Fibroblasts; Fibronectins; Freeze Drying; Gels; Growth Inhibitors; Humans; Nicotiana; Pulmonary Disease, Chronic Obstructive; Smoke; Smoking; Transforming Growth Factor beta; Volatilization | 2001 |