acrolein and Pain
acrolein has been researched along with Pain in 29 studies
Research
Studies (29)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.45) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (34.48) | 29.6817 |
| 2010's | 15 (51.72) | 24.3611 |
| 2020's | 3 (10.34) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Basbaum, AI; Bautista, DM; Jordt, SE; Julius, D; Nikai, T; Poblete, J; Read, AJ; Tsuruda, PR; Yamoah, EN | 1 |
| Cravatt, BF; Dubin, AE; Evans, MJ; Macpherson, LJ; Marr, F; Patapoutian, A; Schultz, PG | 1 |
| Baraldi, PG; Geppetti, P; Materazzi, S; Preti, D | 1 |
| Malekzadeh Shafaroudi, A; Molania, T; Moosazadeh, M; Rostamkalaei, SS; Saeedi, M; Salehabadi, N; Salehi, M; Valipour, F | 1 |
| Fan, Z; Qi, C; Quan, X; Wang, X; Wu, S; Wu, T; Yu, C; Zhang, H | 1 |
| Chen, Z; Herr, SA; Jiao, Y; Lin, Y; Rogers, E; Shi, L; Shi, R; Tang, J | 1 |
| Baggio, CH; Cipriani, TR; da Silva, CF; de Souza, LM; Hamm, LA; Nascimento, AM; Nomura, EC; Rodrigues, MR; Werner, MF | 1 |
| Chapman, H; Jalava, N; Koivisto, A; Korjamo, T; Lindstedt, K; Pertovaara, A; Saarnilehto, M | 1 |
| Chen, P; Li, Y; Tang, C; Wang, Y; Zhang, H | 1 |
| Athayde, ML; Boligon, AA; Ferreira, J; Hoffmeister, C; Klafke, JZ; Pinheiro, FV; Pinheiro, KV; Rosa, F; Rossato, MF; Tonello, R; Trevisan, G | 1 |
| Imam, MZ; Khatun, A; Rana, MS | 1 |
| DeBerry, JJ; Dewberry, LS; Sorge, RE; Taylor, JC; Totsch, SK; Watts, SA; Yessick, LR | 1 |
| Babes, A; Barbu, I; Ciobanu, C; Kerek, F; Neacsu, C; Szegli, G; Toader, O | 1 |
| Bi, H; Ji, W; Liang, J | 1 |
| Abzianidze, E; Carstens, E; Carstens, MI; Gurtskaia, G; Klein, AH; Sawyer, CM; Tsagareli, MG; Tsiklauri, N; Zanotto, KL | 1 |
| Córdova, MM; Pizzolatti, MG; Ruani, AP; Santos, AR; Silva, MD; Werner, MF | 1 |
| Bang, S; Cho, H; Hwang, SW; Yang, TJ; Yoo, S | 1 |
| Anand, P; Roberts, K; Shenoy, R | 1 |
| Alenmyr, L; Greiff, L; Herrmann, A; Högestätt, ED; Zygmunt, PM | 1 |
| Averbeck, B; Carr, RW; Laubender, RP; Rucker, F | 1 |
| Boucher, M; Coudoré-Civiale, MA; Eschalier, A; Méen, M; Parry, L | 1 |
| Bandell, M; Earley, TJ; Eid, SR; Hwang, SW; Patapoutian, A; Petrus, MJ; Story, GM; Viswanath, V | 1 |
| Avelino, A; Bevan, S; Charrua, A; Cruz, F; Dinis, P; Nagy, I; Yaqoob, M | 1 |
| Handwerker, HO; Maihöfner, C; Namer, B; Seifert, F | 1 |
| Caterina, MJ | 1 |
| Dai, Y; Fukuoka, T; Higashi, T; Kobayashi, K; Noguchi, K; Obata, K; Tominaga, M; Wang, S; Yamamoto, S; Yamanaka, H | 1 |
| Andrè, E; Basbaum, AI; Bautista, DM; Bunnett, NW; Campi, B; Cottrell, GS; Gatti, R; Geppetti, P; Imamachi, N; Julius, D; Materazzi, S; Nassini, R; Patacchini, R; Siemens, J; Trevisani, M | 1 |
| Handwerker, H; Jorum, E; Kleggetveit, IP; Namer, B; Schmelz, M | 1 |
| Parker, CM; Smith, GG; Sprince, H | 1 |
Reviews
2 review(s) available for acrolein and Pain
| Article | Year |
|---|---|
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Peripheral Nervous System Diseases; Pulmonary Disease, Chronic Obstructive; Transient Receptor Potential Channels | 2010 |
TRPA1: a transducer and amplifier of pain and inflammation.
Topics: Acetanilides; Acrolein; Aldehydes; Animals; Ankyrins; Humans; Inflammation; Mustard Plant; Oximes; Pain; Plant Oils; Purines; Spinal Cord; Transient Receptor Potential Channels | 2014 |
Trials
4 trial(s) available for acrolein and Pain
| Article | Year |
|---|---|
Evaluation of cinnamaldehyde mucoadhesive patches on minor recurrent aphthous stomatitis: a randomized, double-blind, placebo-controlled clinical trial.
Topics: Acrolein; Double-Blind Method; Humans; Pain; Retrospective Studies; Stomatitis, Aphthous; Treatment Outcome | 2022 |
TRPV1 and TRPA1 stimulation induces MUC5B secretion in the human nasal airway in vivo.
Topics: Acrolein; Administration, Intranasal; Adult; Aged; Arachidonic Acids; Biopsy; Calcium; Calcium Channels; Capsaicin; Cilia; Cross-Over Studies; Double-Blind Method; Endocannabinoids; Humans; Immunohistochemistry; Methanol; Middle Aged; Movement; Mucin 5AC; Mucin-5B; Mustard Plant; Nasal Lavage; Nasal Mucosa; Nerve Tissue Proteins; Pain; Pain Measurement; Plant Oils; Polyunsaturated Alkamides; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Sensory System Agents; Sweden; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels; Young Adult | 2011 |
TRPA1 and TRPM8 activation in humans: effects of cinnamaldehyde and menthol.
Topics: Acrolein; Adult; Axons; Cross-Over Studies; Double-Blind Method; Female; Humans; Hyperalgesia; Ion Channels; Laser-Doppler Flowmetry; Male; Menthol; Neoplasm Proteins; Pain; Pain Measurement; Pain Threshold; Reflex; Time Factors; TRPM Cation Channels; Vasodilation | 2005 |
Role of TRPM8 and TRPA1 for cold allodynia in patients with cold injury.
Topics: Acrolein; Adult; Afferent Pathways; Calcium Channels; Cold Temperature; Cross-Over Studies; Double-Blind Method; Humans; Menthol; Nerve Fibers, Unmyelinated; Nerve Tissue Proteins; Nociceptors; Pain; Pain Threshold; Thermosensing; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels | 2008 |
Other Studies
23 other study(ies) available for acrolein and Pain
| Article | Year |
|---|---|
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents.
Topics: Acrolein; Animals; Cold Temperature; Evoked Potentials, Auditory, Brain Stem; Garlic; Inflammation; Inhalation Exposure; Mice; Mice, Knockout; Molecular Structure; Nociceptors; Pain; Thermoreceptors; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2006 |
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines.
Topics: Acrolein; Animals; Cysteine; Disulfides; Dithiothreitol; Electric Conductivity; Ethyl Methanesulfonate; Humans; Ion Channel Gating; Mice; Mustard Plant; Noxae; Pain; Plant Oils; Transient Receptor Potential Channels | 2007 |
Hydralazine plays an immunomodulation role of pro-regeneration in a mouse model of spinal cord injury.
Topics: Acrolein; Animals; Hydralazine; Macrophages; Male; Mice; Pain; Rats; Spinal Cord; Spinal Cord Injuries | 2023 |
Acrolein scavenger dimercaprol offers neuroprotection in an animal model of Parkinson's disease: implication of acrolein and TRPA1.
Topics: Acrolein; Animals; Behavior, Animal; Cerebral Cortex; Dimercaprol; Dopaminergic Neurons; Hydroxydopamines; Male; Motor Activity; Neostriatum; Neuroprotective Agents; Pain; Pain Measurement; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Substantia Nigra; TRPA1 Cation Channel | 2021 |
Antinociceptive effects of ethanolic extract from the flowers of Acmella oleracea (L.) R.K. Jansen in mice.
Topics: Acrolein; Analgesics; Animals; Asteraceae; Capsaicin; Ethanol; Flowers; Formaldehyde; Hot Temperature; Hyperalgesia; Ligation; Male; Mice; Pain; Phytotherapy; Plant Extracts; Sciatic Nerve; Solvents; Touch | 2013 |
Antinociceptive and anti-inflammatory activities of extract and two isolated flavonoids of Carthamus tinctorius L.
Topics: Acetic Acid; Acrolein; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Carthamus tinctorius; Ear; Edema; Female; Foot; Glucosides; Kaempferols; Male; Mice; Pain; Phytotherapy; Plant Extracts; Xylenes | 2014 |
Gallic acid functions as a TRPA1 antagonist with relevant antinociceptive and antiedematogenic effects in mice.
Topics: Acrolein; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Edema; Gallic Acid; Hydrogen Peroxide; Hyperalgesia; Male; Mice; Pain; Psychomotor Performance; Sciatic Nerve; Spinal Cord; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2014 |
Antinociceptive effect of methanol extract of leaves of Persicaria hydropiper in mice.
Topics: Acetic Acid; Acrolein; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Bangladesh; Behavior, Animal; Formaldehyde; Glutamic Acid; Male; Medicine, Traditional; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Phytotherapy; Plant Extracts; Plant Leaves; Polygonum | 2015 |
A novel zebrafish-based model of nociception.
Topics: Acetic Acid; Acrolein; Analgesics, Opioid; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Histamine; Histamine Agonists; Male; Morphine; Mustard Plant; Naloxone; Narcotic Antagonists; Nociception; Pain; Plant Oils; Swimming; Zebrafish | 2017 |
Substance MCS-18 isolated from Helleborus purpurascens is a potent antagonist of the capsaicin receptor, TRPV1, in rat cultured sensory neurons.
Topics: Acids; Acrolein; Animals; Biological Products; Calcium; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Ganglia, Spinal; Helleborus; Hot Temperature; Membrane Potentials; Pain; Patch-Clamp Techniques; Rats; Sensory Receptor Cells; TRPV Cation Channels | 2010 |
Involvement of TRPA1 in ET-1-induced pain-like behavior in mice.
Topics: Acrolein; Animals; Behavior, Animal; Endothelin-1; Enzyme Inhibitors; Irritants; Male; Mice; Mice, Inbred C57BL; Pain; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2010 |
Behavioral evidence of thermal hyperalgesia and mechanical allodynia induced by intradermal cinnamaldehyde in rats.
Topics: Acrolein; Animals; Ankyrins; Behavior, Animal; Calcium Channel Agonists; Calcium Channels; Cold Temperature; Hot Temperature; Hyperalgesia; Injections, Intradermal; Male; Pain; Rats; Rats, Sprague-Dawley; Touch; TRPA1 Cation Channel; TRPC Cation Channels | 2010 |
Further antinociceptive effects of myricitrin in chemical models of overt nociception in mice.
Topics: Acrolein; Amiloride; Analgesics, Non-Narcotic; Animals; Bradykinin; Camphor; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Flavonoids; Functional Laterality; Hyperalgesia; Male; Mice; Models, Chemical; Pain; Pain Measurement; Pain Threshold; Ruthenium Red | 2011 |
Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels.
Topics: Acrolein; Analgesics; Animals; Calcium; Calcium Channels; Cells, Cultured; Disease Models, Animal; Freund's Adjuvant; Ganglia, Spinal; Gene Expression Regulation; Hemiterpenes; Humans; Inflammation; Membrane Potentials; Mice; Mice, Inbred ICR; Mice, Knockout; Nerve Tissue Proteins; Organophosphorus Compounds; Pain; Patch-Clamp Techniques; RNA, Messenger; RNA, Small Interfering; Sensory Receptor Cells; Transfection; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels | 2011 |
A novel human volunteer pain model using contact heat evoked potentials (CHEP) following topical skin application of transient receptor potential agonists capsaicin, menthol and cinnamaldehyde.
Topics: Acrolein; Adult; Capsaicin; Electroencephalography; Evoked Potentials; Female; Hot Temperature; Human Experimentation; Humans; Male; Menthol; Middle Aged; Models, Biological; Pain; Pain Measurement; Pain Threshold; Sensory System Agents; Skin; Transient Receptor Potential Channels; Young Adult | 2011 |
Thermal grill-evoked sensations of heat correlate with cold pain threshold and are enhanced by menthol and cinnamaldehyde.
Topics: Acrolein; Adult; Cold Temperature; Female; Hot Temperature; Humans; Male; Menthol; Nociceptors; Pain; Pain Measurement; Pain Threshold; Skin; Thermosensing | 2013 |
Involvement of N-methyl-D-aspartate receptors in nociception in the cyclophosphamide-induced vesical pain model in the conscious rat.
Topics: Acrolein; Animals; Antineoplastic Agents, Alkylating; Behavior, Animal; Cyclophosphamide; Cystitis; Dizocilpine Maleate; Dose-Response Relationship, Drug; Injections, Intravenous; Injections, Spinal; Ketamine; Male; Models, Animal; Pain; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2002 |
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin.
Topics: Acrolein; Animals; Behavior, Animal; Bradykinin; Cell Membrane; CHO Cells; Cold Temperature; Cricetinae; Dose-Response Relationship, Drug; Humans; Inflammation Mediators; Ion Channels; Membrane Potentials; Mice; Neurons, Afferent; Nociceptors; Pain; Pain Measurement; Rats; Transient Receptor Potential Channels; TRPA1 Cation Channel; Type C Phospholipases | 2004 |
Anandamide-evoked activation of vanilloid receptor 1 contributes to the development of bladder hyperreflexia and nociceptive transmission to spinal dorsal horn neurons in cystitis.
Topics: Acrolein; Animals; Arachidonic Acids; Capsaicin; Cyclophosphamide; Cystitis; Endocannabinoids; Female; Hydrolysis; Ion Channels; Pain; Polyunsaturated Alkamides; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Reflex, Abnormal; TRPV Cation Channels; Urinary Bladder | 2004 |
Chemical biology: sticky spices.
Topics: Acrolein; Animals; Cysteine; Humans; Ion Channel Gating; Mice; Mustard Plant; Pain; Plant Oils; Spices; Taste; Transient Receptor Potential Channels | 2007 |
Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain.
Topics: Acrolein; Animals; Ankyrins; Behavior, Animal; Calcium Channels; Cell Line; Electrophysiology; Enzyme Activation; Ganglia, Spinal; Gene Expression Regulation; Humans; Inflammation; Isothiocyanates; Male; Nerve Tissue Proteins; Pain; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, PAR-2; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels; Type C Phospholipases | 2007 |
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
Topics: Acrolein; Aldehydes; Ankyrins; Calcium Channels; Cell Line; Cloning, Molecular; Humans; Inflammation; Pain; Patch-Clamp Techniques; TRPA1 Cation Channel; TRPC Cation Channels | 2007 |
Comparison of protection by L-ascorbic acid, L-cysteine, and adrenergic-blocking agents against acetaldehyde, acrolein, and formaldehyde toxicity: implications in smoking.
Topics: Acetaldehyde; Acrolein; Adrenergic beta-Antagonists; Aldehydes; Anesthesia; Animals; Ascorbic Acid; Cysteine; Formaldehyde; Humans; Infant, Newborn; Male; Pain; Rats; Respiratory Distress Syndrome, Newborn; Smoking; Time Factors | 1979 |