acrolein has been researched along with Lung Neoplasms in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (11.76) | 18.7374 |
| 1990's | 5 (14.71) | 18.2507 |
| 2000's | 6 (17.65) | 29.6817 |
| 2010's | 15 (44.12) | 24.3611 |
| 2020's | 4 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Peterson, LA; Seabloom, D; Seelig, DM; Smith, WE; Vevang, KR; Wiedmann, TS; Zhang, L | 1 |
| Igarashi, K; Kashiwagi, K; Sakamoto, A; Terui, Y | 1 |
| Baek, SH; Park, J | 1 |
| Bryant, M; Cao, X; Healy, S; Rosenfeldt, H; Wu, Q; Xiong, R | 1 |
| Tian, F; Wang, Q; Ye, WD; Yu, CT | 1 |
| Sarkar, P | 1 |
| Agarwal, AR; Cadenas, E; Yin, F | 1 |
| Cao, D; Cao, Z; Chen, X; Huang, D; Huang, H; Wang, Y; Wang, Z; Zhang, X; Zhou, B | 1 |
| Kim, SY; Lee, HJ; Lee, YS; Nam, JW; Seo, EK | 1 |
| Carmella, SG; Chen, M; Hecht, SS; Koh, WP; Murphy, SE; Wang, R; Yuan, JM | 1 |
| Carmella, SG; Chen, M; Haiman, CA; Hecht, SS; Le Marchand, L; Park, SL; Patel, Y; Stram, DO | 1 |
| Chen, LC; Chin, C; Huang, W; Lee, HW; Lepor, H; Rom, WN; Tang, MS; Wang, HT; Weng, MW; Wu, XR | 1 |
| Chang, CM; Chen, TW; Cherng, J; Cherng, JM; Chou, KS; Liu, YH; Tsai, KD; Wong, HY; Yang, SM; Yao, BT | 1 |
| Chen, TW; Cherng, J; Cherng, JM; Liu, YH; Tsai, KD; Wong, HY; Yang, SM | 1 |
| Chen, TY; Tang, MS; Wang, HT; Weng, CW; Yang, CH | 1 |
| Chen, X; Jiang, S; Liu, S; Teng, Y; Tian, F; Wang, R; Wu, C; Wu, J; Zheng, P; Zhou, J; Zhuang, Y; Zou, X | 1 |
| Hu, Y; Tang, MS; Wang, HT; Zhang, S | 1 |
| Burcham, PC; Thompson, CA | 1 |
| Burcham, PC; Raso, A; Thompson, CA | 1 |
| Akao, M; Chen, WS; Feng, Z; Hu, W; Hu, Y; Tang, MS; Wang, HT | 1 |
| Bein, K; Leikauf, GD | 1 |
| Biswal, S; Kehrer, JP; Maxwell, T; Rangasamy, T | 1 |
| Feng, Z; Hu, W; Hu, Y; Tang, MS | 1 |
| Hecht, SS | 1 |
| Bryant, BM; Ford, HT; Jarman, M; Smith, IE | 1 |
| Saiers, JH; Slavik, M | 1 |
| Ahmed, T; Kehrer, JP; Pakenham, G; Perry, CS; Ramu, K | 1 |
| Horton, ND; Kehrer, JP; Mamiya, BM | 1 |
| Biswal, SS; Bratta, J; Corrigan, LL; Horton, ND; Kehrer, JP | 1 |
| Borchers, MT; Carty, MP; Leikauf, GD | 1 |
| Acquaah-Mensah, G; Biswal, S; Datta, K; Kehrer, JP; Wu, X | 1 |
| Carlens, E | 1 |
| Grafström, RC | 1 |
| Wardle, EN | 1 |
2 review(s) available for acrolein and Lung Neoplasms
| Article | Year |
|---|---|
Acrolein induced DNA damage, mutagenicity and effect on DNA repair.
Topics: Acrolein; Animals; Carcinogenicity Tests; Carcinogens; DNA Adducts; DNA Damage; DNA Repair; Humans; Lipid Peroxidation; Lung Neoplasms; Mutagenicity Tests; Mutation; Rats; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms | 2011 |
Acrolein - a pulmonary hazard.
Topics: Acrolein; Animals; Apoptosis; Asthma; Bronchitis; Cooking; DNA Adducts; Gene Expression Regulation; Humans; Lung Neoplasms; Pulmonary Disease, Chronic Obstructive; Toxicity Tests, Acute; Tumor Suppressor Protein p53 | 2011 |
1 trial(s) available for acrolein and Lung Neoplasms
| Article | Year |
|---|---|
Prevention of isophosphamide-induced urothelial toxicity with 2-mercaptoethane sulphonate sodium (mesnum) in patients with advanced carcinoma.
Topics: Acrolein; Carcinoma, Bronchogenic; Clinical Trials as Topic; Cyclophosphamide; Female; Hematuria; Humans; Ifosfamide; Kinetics; Lung Neoplasms; Male; Mercaptoethanol; Mesna; Phosphoramide Mustards; Urinary Bladder | 1980 |
31 other study(ies) available for acrolein and Lung Neoplasms
| Article | Year |
|---|---|
Acrolein Increases the Pulmonary Tumorigenic Activity of the Tobacco-Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
Topics: Acrolein; Adenoma; Animals; Butanones; Carcinogenesis; Carcinogens; DNA Adducts; Humans; Lung; Lung Neoplasms; Mice; Nicotiana; Nitrosamines; Smoke; Tobacco Smoke Pollution | 2022 |
Transient Receptor Potential Ankyrin 1 (TRPA1) Channel Mediates Acrolein Cytotoxicity in Human Lung Cancer Cells.
Topics: Acrolein; Ankyrins; Cytoskeletal Proteins; Humans; Lung Neoplasms; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2023 |
Combination Therapy with Cinnamaldehyde and Hyperthermia Induces Apoptosis of A549 Non-Small Cell Lung Carcinoma Cells via Regulation of Reactive Oxygen Species and Mitogen-Activated Protein Kinase Family.
Topics: A549 Cells; Acetylcysteine; Acrolein; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Proliferation; Cell Survival; Combined Modality Therapy; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Humans; Hyperthermia, Induced; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; MAP Kinase Signaling System; Phosphorylation; Reactive Oxygen Species | 2020 |
In vitro dosimetry analyses for acrolein exposure in normal human lung epithelial cells and human lung cancer cells.
Topics: Acrolein; Cell Line; Cell Survival; Epithelial Cells; Glutathione; Humans; Lung; Lung Neoplasms; Protein Carbonylation | 2021 |
Cinnamaldehyde induces cell apoptosis mediated by a novel circular RNA hsa_circ_0043256 in non-small cell lung cancer.
Topics: Acrolein; Animals; Apoptosis; beta Catenin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Mice, Inbred BALB C; MicroRNAs; Repressor Proteins; RNA; RNA, Circular; Ubiquitin-Protein Ligases; Wnt Proteins; Xenograft Model Antitumor Assays | 2017 |
Response of DNA damage genes in acrolein-treated lung adenocarcinoma cells.
Topics: Acrolein; Adenocarcinoma; Biomarkers, Tumor; DNA Damage; DNA Repair; DNA Repair Enzymes; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Tumor Cells, Cultured | 2019 |
Metabolic shift in lung alveolar cell mitochondria following acrolein exposure.
Topics: Acrolein; Adenocarcinoma; Animals; Cell Respiration; Cell Survival; Cells, Cultured; Epithelial Cells; Flow Cytometry; Glucose; Glucosephosphate Dehydrogenase; Glycolysis; Humans; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred A; Mitochondria; Oxygen Consumption; Palmitates; Phosphatidylcholines; Phospholipases A2; Pulmonary Alveoli; Rats | 2013 |
Statil suppresses cancer cell growth and proliferation by the inhibition of tumor marker AKR1B10.
Topics: Acrolein; Aldehyde Reductase; Aldo-Keto Reductases; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Diclofenac; DNA Damage; Humans; Lung Neoplasms; Phthalazines | 2014 |
Coniferyl aldehyde reduces radiation damage through increased protein stability of heat shock transcriptional factor 1 by phosphorylation.
Topics: Acrolein; Animals; Antineoplastic Agents, Phytogenic; Bone Marrow Cells; Cell Line, Tumor; DNA-Binding Proteins; Female; Heat Shock Transcription Factors; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; In Situ Nick-End Labeling; Lung Neoplasms; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Paclitaxel; Phosphorylation; Radiation Injuries, Experimental; Radiation-Protective Agents; RNA, Messenger; Transcription Factors; Whole-Body Irradiation | 2015 |
Elevated levels of mercapturic acids of acrolein and crotonaldehyde in the urine of Chinese women in Singapore who regularly cook at home.
Topics: Acetylcysteine; Acrolein; Aged; Aldehydes; Asian People; Benzene; Biomarkers; Carcinogens; Cooking; Female; Humans; Lung Neoplasms; Middle Aged; Singapore; Smoking | 2015 |
Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.
Topics: Acetylcysteine; Acrolein; Aged; Aldehydes; Ethnicity; Female; Hawaii; Humans; Lung Neoplasms; Male; Middle Aged; Risk Factors; Smoking | 2015 |
Cigarette side-stream smoke lung and bladder carcinogenesis: inducing mutagenic acrolein-DNA adducts, inhibiting DNA repair and enhancing anchorage-independent-growth cell transformation.
Topics: Acrolein; Animals; Carcinogenesis; Cell Adhesion; Cell Proliferation; Cell Transformation, Neoplastic; DNA Adducts; DNA Repair; Lung Neoplasms; Male; Mice; Smoke; Tobacco Products; Urinary Bladder Neoplasms | 2015 |
Cinnamomum verum Component 2-Methoxycinnamaldehyde: A Novel Anticancer Agent with Both Anti-Topoisomerase I and II Activities in Human Lung Adenocarcinoma A549 Cells In Vitro and In Vivo.
Topics: Acrolein; Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cinnamomum zeylanicum; Cytochromes c; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Humans; Lung Neoplasms; Male; Membrane Potential, Mitochondrial; Mice; Mice, Nude; NF-kappa B; Topoisomerase Inhibitors; Xenograft Model Antitumor Assays | 2016 |
Cinnamomum verum ingredient 2-methoxycinnamaldehyde: a new antiproliferative drug targeting topoisomerase I and II in human lung squamous cell carcinoma NCI-H520 cells.
Topics: Acrolein; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Squamous Cell; Cell Proliferation; Cinnamomum; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Humans; Lung Neoplasms; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Poly-ADP-Ribose Binding Proteins; Xenograft Model Antitumor Assays | 2017 |
Acrolein preferentially damages nucleolus eliciting ribosomal stress and apoptosis in human cancer cells.
Topics: A549 Cells; Acrolein; Antineoplastic Agents; Apoptosis; Binding Sites; Cell Nucleolus; DNA Adducts; DNA, Ribosomal; Dose-Response Relationship, Drug; E2F1 Transcription Factor; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Lung Neoplasms; Oxidative Stress; Promoter Regions, Genetic; Protein Stability; Proteolysis; Proto-Oncogene Proteins c-mdm2; Ribosomal Proteins; Ribosomes; RNA Polymerase I; RNA, Ribosomal; Signal Transduction; Time Factors; Tumor Suppressor Protein p53; Uterine Cervical Neoplasms | 2016 |
Cinnamaldehyde induces apoptosis and reverses epithelial-mesenchymal transition through inhibition of Wnt/β-catenin pathway in non-small cell lung cancer.
Topics: A549 Cells; Acrolein; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; beta Catenin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cobalt; Dose-Response Relationship, Drug; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2017 |
Mutagenicity and sequence specificity of acrolein-DNA adducts.
Topics: Acrolein; Animals; Base Sequence; Deoxyguanine Nucleotides; Deoxyguanosine; DNA Adducts; DNA Repair; Genes, p53; Humans; Lung Neoplasms; Mice; Mutagenesis; Smoking | 2009 |
Genome-wide transcriptional responses to acrolein.
Topics: Acrolein; Antigens, Differentiation; Blotting, Western; Cell Line, Tumor; Cell Survival; DNA Fragmentation; DNA-Binding Proteins; Early Growth Response Protein 2; Environmental Pollutants; Epithelial Cells; Gene Expression Regulation, Neoplastic; Genome; Heme Oxygenase-1; HSP70 Heat-Shock Proteins; Humans; Lung Neoplasms; Nuclear Receptor Subfamily 4, Group A, Member 1; Oligonucleotide Array Sequence Analysis; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Up-Regulation | 2008 |
Toxicity of smoke extracts towards A549 lung cells: role of acrolein and suppression by carbonyl scavengers.
Topics: Acrolein; Adenosine Triphosphate; Cell Line, Tumor; Early Growth Response Protein 1; Free Radical Scavengers; GADD45 Proteins; Heme Oxygenase-1; HSP70 Heat-Shock Proteins; Humans; Intracellular Signaling Peptides and Proteins; Keratin-18; Keratin-7; Keratin-8; Lung Neoplasms; NAD(P)H Dehydrogenase (Quinone); Nuclear Receptor Subfamily 4, Group A, Member 1; Polyethylene; Protein Carbonylation; Smoke; Vimentin | 2010 |
Modulation of benzo[a]pyrene-induced p53 DNA activity by acrolein.
Topics: Acrolein; Adenocarcinoma; Antimetabolites, Antineoplastic; Benzo(a)pyrene; Blotting, Western; Buthionine Sulfoximine; DNA, Neoplasm; Electrophoretic Mobility Shift Assay; Glutathione; Humans; Luciferases; Lung Neoplasms; Precipitin Tests; Promoter Regions, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2003 |
Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair.
Topics: Acrolein; Binding Sites; Carcinogens; Cell Line; CpG Islands; DNA Adducts; DNA Damage; DNA Methylation; DNA Repair; Humans; Lung Neoplasms; Molecular Structure; Mutation; Smoking; Tumor Suppressor Protein p53 | 2006 |
Smoking and lung cancer--a new role for an old toxicant?
Topics: Acrolein; Carcinogens; DNA Damage; Humans; Lung Neoplasms; Smoking | 2006 |
Phase I clinical study of acetylcysteine's preventing ifosfamide-induced hematuria.
Topics: Acetylcysteine; Acrolein; Adenocarcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Cystitis; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Hematuria; Humans; Ifosfamide; Lung Neoplasms | 1983 |
Studies on the basis for the toxicity of acrolein mercapturates.
Topics: Acetylcysteine; Acrolein; Adenocarcinoma; Cyclophosphamide; Growth Inhibitors; Humans; Lung Neoplasms; Tumor Cells, Cultured | 1996 |
Relationships between cell density, glutathione and proliferation of A549 human lung adenocarcinoma cells treated with acrolein.
Topics: Acrolein; Adenocarcinoma; CCAAT-Enhancer-Binding Proteins; Cell Count; Cell Division; Cell Survival; DNA-Binding Proteins; Glutathione; Growth Inhibitors; HSP70 Heat-Shock Proteins; Humans; Lung Neoplasms; Nuclear Proteins; Transcription Factor CHOP; Transcription Factors; Tumor Cells, Cultured | 1997 |
Acrolein causes inhibitor kappaB-independent decreases in nuclear factor kappaB activation in human lung adenocarcinoma (A549) cells.
Topics: Acrolein; Adenocarcinoma; Cell Division; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Humans; I-kappa B Proteins; Lung Neoplasms; Maleates; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Regulation of human airway mucins by acrolein and inflammatory mediators.
Topics: Acrolein; Carcinoma, Mucoepidermoid; Dinoprostone; Gene Expression Regulation; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Kinetics; Lung Neoplasms; Mucin 5AC; Mucin-5B; Mucins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Inhibition of cell proliferation and AP-1 activity by acrolein in human A549 lung adenocarcinoma cells due to thiol imbalance and covalent modifications.
Topics: Acrolein; Adenocarcinoma; Cell Division; DNA Damage; Glutathione; Humans; Lung Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-jun; Transcription Factor AP-1; Tumor Cells, Cultured | 2002 |
[Are we hunting the wrong villain in the cigarette?].
Topics: Acrolein; Bronchi; Bronchial Neoplasms; Carcinogens; Cyanides; Formaldehyde; Humans; Lung Neoplasms; Mucous Membrane; Smoking | 1978 |
In vitro studies of aldehyde effects related to human respiratory carcinogenesis.
Topics: Acrolein; Aldehydes; Bronchi; Calcium; Cell Division; Cell Membrane; Cell Survival; Cells, Cultured; DNA Damage; DNA Repair; Epithelium; Fibroblasts; Formaldehyde; Humans; Lung Neoplasms; Sulfhydryl Compounds | 1990 |
Alveolar cell carcinoma in a cook.
Topics: Acrolein; Adenocarcinoma, Bronchiolo-Alveolar; Aged; Cooking; Female; Humans; Lung Neoplasms; Occupational Diseases | 1988 |