acrolein has been researched along with Inflammation in 69 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (4.35) | 18.2507 |
| 2000's | 9 (13.04) | 29.6817 |
| 2010's | 36 (52.17) | 24.3611 |
| 2020's | 21 (30.43) | 2.80 |
| Authors | Studies |
|---|---|
| Basbaum, AI; Bautista, DM; Jordt, SE; Julius, D; Nikai, T; Poblete, J; Read, AJ; Tsuruda, PR; Yamoah, EN | 1 |
| Gu, Y; He, Y; Jiang, Y; Li, Q; Zhou, W | 1 |
| Andersen-Civil, AIS; Blanchard, A; Kot, W; Krych, L; Myhill, LJ; Nielsen, DS; Thamsborg, SM; Williams, AR; Zhu, L | 1 |
| Gulec Peker, EG; Kaltalioglu, K | 1 |
| Batish, M; Kim, JK; Kim, YJ; Lee, JH; Pan, JH; Redding, MC; Trabulsi, J | 1 |
| Abdel-Reheim, ES; Ali, TM; Elesawy, BH; Ismail, BS; Mahmoud, B; Soliman, HA; Zaky, MY | 1 |
| Chen, W; Cheng, M; Fan, L; Liu, W; Ma, J; Nie, X; Qiu, W; Song, J; Wang, B; Wang, X; Yang, M; Ye, Z; Yu, L; Zhou, M | 1 |
| Fan, D; Jiang, Q; Liu, N; Wang, M; Yu, J; Zhao, Y | 1 |
| Alewel, DI; Evansky, PA; Gavett, SH; Grindstaff, R; Henriquez, AR; Jackson, TW; Kodavanti, UP; Schladweiler, MC; Vance, SA | 1 |
| Beauclair, T; Crodian, J; Dieterly, AM; Kim, D; Krishnan, N; Martinez, J; Mufti, SJ; Rogers, EA; Shi, R; Stingel, RL; Sun, S | 1 |
| Guo, K; Ma, T; Qi, CC; Quan, X; Song, BQ; Wang, H; Yu, CY | 1 |
| Ahn, SG; Kim, NY; Kim, SA; Trinh, NT | 1 |
| Barre, DE; Mizier-Barre, KA | 1 |
| Gao, Y; Li, X; Nie, R; Sun, X; Wang, H; Wang, Y; Wang, Z; Yu, W; Zhou, Y | 1 |
| Chen, ZD; Jiang, YY; Wierzbicki, PM; Wu, JR; Zhong, WJ; Zhu, BQ | 1 |
| Dabzadeh, M; Forouzanfar, F; Ghaddaripouri, M; Hajinejad, M; Sahab-Negah, S | 1 |
| Epifano, F; Fiorito, S; Genovese, S; Ibuka, T; Ideta, T; Kubota, M; Maruta, A; Miyazaki, T; Mizutani, T; Sakai, H; Shimizu, M; Shirakami, Y; Taddeo, VA; Tanaka, T | 1 |
| Bulimbasic, S; Galesic Ljubanovic, D; Galesic, K; Jaganjac, M; Mitrovic, J; Morovic-Vergles, J; Sredoja Tisma, V; Tatzber, F; Uchida, K; Zarkovic, N | 1 |
| Dai, Z; Jia, H; Lei, Y; Li, S; Lyu, J; Si, X; Wang, R; Wu, Z | 1 |
| Choi, SH; Choi, YH; Hong, S; Hong, SH; Jeong, JW; Jin, CY; Kim, GY; Lee, H; Molagoda, IMN; Park, C | 1 |
| Ding, Z; Liu, J; Lv, M; Qian, H; Wu, L | 1 |
| Chen, W; Feng, X; Liang, R; Shi, D; Wang, D; Xu, T | 1 |
| Chug, N; Marek, K; Mathew, J; Nesbary, A; Newaz, MA; Ranganna, K; Yousefipour, Z | 1 |
| Anjum, S; Ashraf, MU; Bhatti, A; John, P; Qadir, MMF; Sandhu, MA | 1 |
| Clapp, PW; Glish, GL; Jaspers, I; Keating, JE; Lackey, JT; Pawlak, EA; Reeber, SL | 1 |
| Claeson, AS; Fowler, CJ; Gouveia-Figueira, S; Häggström, J; Nording, ML | 1 |
| Lee, SC; Li, CC; Liu, CT; Wang, SY | 1 |
| Habing, G; Holder, E; Masterson, M; Pempek, JA; Proudfoot, KL | 1 |
| Chung, J; Kim, S; Lee, HA; Na, HS; Park, MH; Song, YR | 1 |
| Chen, A; Feng, Q; Haq, IU; Jiang, P; Li, C; Mariyam, Z; Wu, X; Zeb, F; Zhou, M | 1 |
| Abou El-Ezz, D; El-Brairy, A; Kenawy, S; Maher, A; Sallam, N | 1 |
| Qu, S; Shen, Y; Wang, M; Wang, X; Yang, Y | 1 |
| Ahmad, S; Akhtar, K; Khalid, S; Mateen, S; Moin, S; Naeem, SS; Rizvi, W; Shahzad, S | 1 |
| Hayes, AW; Karimani, A; Karimi, G; Mehri, S; Zeinali, M; Zirak, MR | 1 |
| Córdova, MM; Montrucchio, DP; Santos, AR | 1 |
| Newaz, M; Yousefipour, Z | 1 |
| Baba, SP; Barski, OA; Bhatnagar, A; Cai, J; Conklin, DJ; Hoetker, JD; Klein, JB; Merchant, M | 1 |
| Chapman, H; Jalava, N; Koivisto, A; Korjamo, T; Lindstedt, K; Pertovaara, A; Saarnilehto, M | 1 |
| Allette, YM; Due, MR; Park, J; Shi, R; Walls, M; White, FA; Zheng, L | 1 |
| Mizuno, S; Voelkel, NF; Yasuo, M | 1 |
| Comer, DM; Elborn, JS; Ennis, M | 1 |
| Chen, N; Isobe, K; Ito, S; Liu, L; Nishio, N; Sun, Y; Tanaka, Y | 1 |
| Bauer, RA; Habibovic, A; Hristova, M; O'Brien, E; Poynter, ME; Randall, MJ; Spiess, PC; van der Vliet, A | 1 |
| Blalock, JE; Davis, VA; Jackson, PL; Jones, CW; Noerager, BD; Okafor, S; Whitehead, A; Xu, X | 1 |
| Al-Salihi, M; Fitzpatrick, FA; Reichert, E | 1 |
| Ana, ID; Dewi, AH; Jansen, J | 1 |
| Bast, A; Bouwman, FG; Haenen, GR; Randall, MJ; van der Vliet, A | 1 |
| Dwivedi, AM; Ernstgård, L; Johanson, G; Lorentzen, JC; Palmberg, L; Sjögren, B | 1 |
| Gong, Y; Li, J; Liang, Y; Tu, L; Wei, M; Yang, L; Zhang, Y | 1 |
| Chen, YF; Huang, WS; Lee, MM; Leung, YM; Tsai, HY; Wang, YW; Wood, WG | 1 |
| Aldini, G; Batignani, G; Becatti, M; Capaccioli, S; Carini, M; Fiorillo, C; Lulli, M; Orioli, M; Pavoni, V; Piccini, M; Witort, E | 1 |
| Akram, M; Bae, ON; Chang, SY; Kim, E; Kim, ES; Kim, JH; Kim, JK; Kim, KA; Majid, A; Noh, D; Shin, YJ | 1 |
| Adolfse, SJ; Ahad, DS; Brüggemann, H; Burt, SA; Jongerius-Gortemaker, BG; Post, JA; Santos, RR; Tersteeg-Zijderveld, MH | 1 |
| Chen, L; Duan, YP; Feng, YL; Hu, XR; Lin, J; Liu, DS; Liu, Y; Ou, XM; Wang, T; Wang, X; Wen, FQ; Xu, D | 1 |
| Han, YM; Hong, SH; Hwang, H; Jeon, H; Kwon, BM; Lee, MS; Lee, WH; Ock, J; Suk, K | 1 |
| Bang, S; Cho, H; Hwang, SW; Yang, TJ; Yoo, S | 1 |
| Facchinetti, F; Moretto, N; Pastore, F; Volpi, G | 1 |
| Ahn, SG; Hong, SH; Kim, SA; Kwon, BM; Kwon, JY; Park, SD; Yoon, JH | 1 |
| Borovic, S; Cindric, M; Cipak, A; Jaganjac, M; Poljak-Blazi, M; Schaur, RJ; Uchida, K; Waeg, G; Zarkovic, K; Zarkovic, N | 1 |
| Calvez, R; Ffoulkes-Jones, C; Kirkham, PA; Spooner, G | 1 |
| Fu, X; Green, PS; Heinecke, JW; McDonald, TO; O'Brien, KD; Oram, JF; Shao, B; Uchida, K | 1 |
| Dai, Y; Fukuoka, T; Higashi, T; Kobayashi, K; Noguchi, K; Obata, K; Tominaga, M; Wang, S; Yamamoto, S; Yamanaka, H | 1 |
| Andrè, E; Basbaum, AI; Bautista, DM; Bunnett, NW; Campi, B; Cottrell, GS; Gatti, R; Geppetti, P; Imamachi, N; Julius, D; Materazzi, S; Nassini, R; Patacchini, R; Siemens, J; Trevisani, M | 1 |
| Go, YM; Halvey, PJ; Hansen, JM; Jones, DP; Pohl, J; Reed, M | 1 |
| Park, YS; Taniguchi, N | 1 |
| Anskeit, E; Friedrichs, B; Moennikes, O; Patskan, GJ; Vanscheeuwijck, PM | 1 |
| Anderson, MM; Hazen, SL; Heinecke, JW; Hsu, FF | 1 |
| Borchers, MT; Carty, MP; Leikauf, GD | 1 |
| Leikauf, GD | 1 |
5 review(s) available for acrolein and Inflammation
| Article | Year |
|---|---|
The polypharmacy reduction potential of cinnamic acids and some related compounds in pre- and post-onset management of type 2 diabetes mellitus.
Topics: Acrolein; Animals; Caffeic Acids; Chlorogenic Acid; Cinnamates; Coumaric Acids; Diabetes Mellitus, Type 2; Dyslipidemias; Humans; Hyperglycemia; Hypertension; Inflammation; Obesity, Abdominal; Polypharmacy | 2020 |
Natural Cinnamaldehyde and Its Derivatives Ameliorate Neuroinflammatory Pathways in Neurodegenerative Diseases.
Topics: Acrolein; Animals; Disease Models, Animal; Disease Progression; Humans; Inflammation; Neurodegenerative Diseases; Neuroprotective Agents | 2020 |
Mechanisms behind the atherothrombotic effects of acrolein, a review.
Topics: Acrolein; Atherosclerosis; Dyslipidemias; Environmental Exposure; Enzyme Activation; Extracellular Matrix; Humans; Inflammation; Matrix Metalloproteinases; Plaque, Atherosclerotic; Thrombosis; Toxicokinetics | 2019 |
TRPA1: a transducer and amplifier of pain and inflammation.
Topics: Acetanilides; Acrolein; Aldehydes; Animals; Ankyrins; Humans; Inflammation; Mustard Plant; Oximes; Pain; Plant Oils; Purines; Spinal Cord; Transient Receptor Potential Channels | 2014 |
Acrolein effects in pulmonary cells: relevance to chronic obstructive pulmonary disease.
Topics: Acrolein; Air Pollutants; Animals; Humans; Inflammation; Lung; Models, Biological; Pulmonary Disease, Chronic Obstructive; Tobacco Smoke Pollution | 2012 |
1 trial(s) available for acrolein and Inflammation
| Article | Year |
|---|---|
Acute effects of acrolein in human volunteers during controlled exposure.
Topics: Acrolein; Biomarkers; Blood Coagulation; Cross-Over Studies; Dose-Response Relationship, Drug; Eye Diseases; Female; Humans; Inflammation; Male; Odorants; Pilot Projects; Sputum | 2015 |
63 other study(ies) available for acrolein and Inflammation
| Article | Year |
|---|---|
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents.
Topics: Acrolein; Animals; Cold Temperature; Evoked Potentials, Auditory, Brain Stem; Garlic; Inflammation; Inhalation Exposure; Mice; Mice, Knockout; Molecular Structure; Nociceptors; Pain; Thermoreceptors; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2006 |
Coniferyl aldehyde alleviates LPS-induced WI-38 cell apoptosis and inflammation injury via JAK2-STAT1 pathway in acute pneumonia.
Topics: Acrolein; Anti-Inflammatory Agents; Apoptosis; Humans; Inflammation; Janus Kinase 2; Lipopolysaccharides; MicroRNAs; Pneumonia; STAT1 Transcription Factor; Tumor Necrosis Factor-alpha | 2021 |
The phytonutrient cinnamaldehyde limits intestinal inflammation and enteric parasite infection.
Topics: Acrolein; Animals; Cells, Cultured; Dietary Supplements; Female; Gastrointestinal Microbiome; Immunity, Mucosal; Inflammation; Intestinal Mucosa; Intestine, Small; Lymph Nodes; Macrophages; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Nematospiroides dubius; Phytochemicals; Strongylida Infections; T-Lymphocytes; Transcription, Genetic; Transcriptome; Xenobiotics | 2022 |
Cinnamaldehyde and eugenol protect against LPS-stimulated oxidative stress and inflammation in Raw 264.7 cells.
Topics: Acrolein; Animals; Eugenol; Inflammation; Lipopolysaccharides; Mice; Oxidative Stress; RAW 264.7 Cells | 2021 |
Apiaceous vegetables protect against acrolein-induced pulmonary injuries through modulating hepatic detoxification and inflammation in C57BL/6 male mice.
Topics: Acrolein; Animals; Apiaceae; Diet; Inactivation, Metabolic; Inflammation; Liver; Lung; Lung Injury; Male; Mice; Mice, Inbred C57BL; Protective Agents; Vegetables | 2022 |
Cinnamaldehyde Mitigates Atherosclerosis Induced by High-Fat Diet
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; Cholesterol, LDL; Creatine Kinase; Diet, High-Fat; Hyperlipidemias; Inflammation; Oxidative Stress; Rats; Rats, Wistar | 2022 |
Cross-sectional and longitudinal associations of acrolein exposure with pulmonary function alteration: Assessing the potential roles of oxidative DNA damage, inflammation, and pulmonary epithelium injury in a general adult population.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acrolein; Adult; Biomarkers; C-Reactive Protein; Cross-Sectional Studies; Cysteine; Epithelium; Humans; Inflammation; Oxidative Stress | 2022 |
Apigenin and apigenin-7, 4'-O-dioctanoate protect against acrolein-aggravated inflammation via inhibiting the activation of NLRP3 inflammasome and HMGB1/MYD88/NF-κB signaling pathway in Human umbilical vein endothelial cells (HUVEC).
Topics: Acrolein; Apigenin; Caspase 1; Environmental Pollutants; Glutathione Peroxidase; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Inflammasomes; Inflammation; Interleukin-18; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Myeloid Differentiation Factor 88; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Nucleotides; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2022 |
Sex-specific respiratory and systemic endocrine effects of acute acrolein and trichloroethylene inhalation.
Topics: Acrolein; Administration, Inhalation; Animals; Female; Inflammation; Male; Rats; Rats, Inbred WKY; Respiratory System; Trichloroethylene | 2023 |
The contribution of initial concussive forces and resulting acrolein surge to β-amyloid accumulation and functional alterations in neuronal networks using a TBI-on-a-chip model.
Topics: Acrolein; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain Injuries, Traumatic; Inflammation; Lab-On-A-Chip Devices; Mice; Tumor Necrosis Factor-alpha | 2023 |
Hydralazine Promotes Central Nervous System Recovery after Spinal Cord Injury by Suppressing Oxidative Stress and Inflammation through Macrophage Regulation.
Topics: Acrolein; Animals; Hydralazine; Inflammation; Macrophages; Mice; Neuralgia; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2023 |
Cinnamaldehyde protects against oxidative stress and inhibits the TNF‑α‑induced inflammatory response in human umbilical vein endothelial cells.
Topics: Acrolein; Animals; Blotting, Western; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Mice; NF-E2-Related Factor 2; Oxidative Stress; Tumor Necrosis Factor-alpha; U937 Cells; Vascular Cell Adhesion Molecule-1 | 2020 |
Coniferyl Aldehyde Inhibits the Inflammatory Effects of Leptomeningeal Cells by Suppressing the JAK2 Signaling.
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Cell Line; Cytokines; Inflammation; Janus Kinase 2; Macrophages; Meninges; Mice; Mice, Inbred C57BL; Microglia; RAW 264.7 Cells; Signal Transduction | 2020 |
The protective impact of Trans-Cinnamaldehyde (TCA) against the IL-1b induced inflammation in in vitro osteoarthritis model by regulating PI3K/AKT pathways.
Topics: Acrolein; Cells, Cultured; Chondrocytes; Dinoprostone; Humans; Inflammation; Interleukin-1beta; Interleukin-8; Osteoarthritis; Phosphatidylinositol 3-Kinase; Protective Agents; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Necrosis Factor-alpha | 2020 |
Novel FXR agonist nelumal A suppresses colitis and inflammation-related colorectal carcinogenesis.
Topics: Acrolein; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred A; RNA-Binding Proteins | 2021 |
The Onset of Systemic Oxidative Stress Associated with the Accumulation of Lipid Peroxidation Product Acrolein in the Skin of Patients with Small-Vessel Vasculitis.
Topics: Acrolein; Adult; Aged; Aged, 80 and over; Blood Vessels; Female; Homeostasis; Humans; Inflammation; Lipid Peroxidation; Male; Middle Aged; Oxidative Stress; Peroxides; Skin; Vasculitis | 2021 |
Protective Effects of Cinnamaldehyde on the Inflammatory Response, Oxidative Stress, and Apoptosis in Liver of
Topics: Acrolein; Animals; Apoptosis; Blotting, Western; DNA, Ribosomal; Gastrointestinal Microbiome; In Situ Nick-End Labeling; Inflammation; Liver; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Salmonella typhimurium; Signal Transduction | 2021 |
Inhibition of Lipopolysaccharide-Induced Inflammatory and Oxidative Responses by
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Disease Models, Animal; Drug Evaluation, Preclinical; Inflammation; Lipopolysaccharides; Mice; Myoblasts; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Toll-Like Receptor 4; Zebrafish | 2021 |
Cinnamaldehyde inhibits psoriasis‑like inflammation by suppressing proliferation and inflammatory response of keratinocytes via inhibition of NF‑κB and JNK signaling pathways.
Topics: Acrolein; Cell Differentiation; Cell Line; Cell Proliferation; Cytokines; Down-Regulation; Epidermis; Humans; Inflammation; Keratinocytes; MAP Kinase Signaling System; NF-kappa B; Oxidative Stress; Phosphorylation; Psoriasis; Signal Transduction; Tumor Necrosis Factor-alpha | 2021 |
Urinary acrolein metabolites, systemic inflammation, and blood lipids: Results from the National Health and Nutrition Examination Survey.
Topics: Acrolein; Cholesterol, HDL; Humans; Inflammation; Lipids; Nutrition Surveys | 2022 |
Contribution of PPARγ in modulation of acrolein-induced inflammatory signaling in gp91
Topics: Acrolein; Animals; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; PPAR gamma; Receptors, Immunologic; Signal Transduction | 2017 |
Immunomodulatory and therapeutic role of Cinnamomum verum extracts in collagen-induced arthritic BALB/c mice.
Topics: Acrolein; Alkaloids; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Cinnamomum zeylanicum; Collagen; Edema; Immunologic Factors; Inflammation; Knee Joint; Lymphocytes; Mice; Mice, Inbred BALB C; Phytotherapy; Plant Extracts; Spleen; Triterpenes; Tumor Necrosis Factor-alpha | 2018 |
Flavored e-cigarette liquids and cinnamaldehyde impair respiratory innate immune cell function.
Topics: Acrolein; Adolescent; Adult; Electronic Nicotine Delivery Systems; Female; Humans; Immunity, Innate; Inflammation; Killer Cells, Natural; Macrophages; Male; Middle Aged; Neutrophils; Nicotine; Phagocytosis; Young Adult | 2017 |
Levels of oxylipins, endocannabinoids and related lipids in plasma before and after low-level exposure to acrolein in healthy individuals and individuals with chemical intolerance.
Topics: Acrolein; Adult; Endocannabinoids; Environmental Pollutants; Female; Healthy Volunteers; Heptanes; Humans; Inflammation; Lipids; Male; Middle Aged; Oxylipins | 2017 |
Anti-inflammatory effect of cinnamaldehyde and linalool from the leaf essential oil of Cinnamomum osmophloeum Kanehira in endotoxin-induced mice.
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Biomarkers; Cinnamomum; Cytokines; Endotoxins; Humans; Inflammation; Inflammation Mediators; Male; Mice; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oils, Volatile; Plant Extracts; Plant Leaves; Signal Transduction | 2018 |
Short communication: Investigation of antibiotic alternatives to improve health and growth of veal calves.
Topics: Acrolein; Animal Feed; Animals; Anti-Bacterial Agents; Body Weight; Cattle; Cattle Diseases; Colostrum; Diarrhea; Diet; Dietary Supplements; Female; Health Status; Inflammation; Lactoferrin; Milk; Weight Gain | 2018 |
Trans-cinnamic aldehyde inhibits Aggregatibacter actinomycetemcomitans-induced inflammation in THP-1-derived macrophages via autophagy activation.
Topics: Acrolein; Aggregatibacter actinomycetemcomitans; Animals; Autophagy; Humans; Inflammation; Lipopolysaccharides; Macrophages; Mice; X-Ray Microtomography | 2018 |
Acrolein-induced atherogenesis by stimulation of hepatic flavin containing monooxygenase 3 and a protection from hydroxytyrosol.
Topics: Acrolein; Animals; Atherosclerosis; ATP Binding Cassette Transporter 1; Biological Transport; Cholesterol; Endothelial Cells; Humans; Inflammation; Lipid Metabolism; Lipoproteins, LDL; Liver; Mice; Oxygenases; Phenylethyl Alcohol; RAW 264.7 Cells; Signal Transduction | 2018 |
Trans-cinnamaldehyde Modulates Hippocampal Nrf2 Factor and Inhibits Amyloid Beta Aggregation in LPS-Induced Neuroinflammation Mouse Model.
Topics: Acrolein; Amyloid beta-Peptides; Animals; Disease Models, Animal; Hippocampus; Inflammation; Lipopolysaccharides; Male; Maze Learning; Mice; NF-E2-Related Factor 2; Protein Aggregation, Pathological; Random Allocation | 2018 |
Suppression of miR-21 and miR-155 of macrophage by cinnamaldehyde ameliorates ulcerative colitis.
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Antigens, Differentiation; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Humans; Inflammasomes; Inflammation; Inflammation Mediators; Interleukin-10; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; MicroRNAs; NLR Family, Pyrin Domain-Containing 3 Protein; RAW 264.7 Cells; Reactive Oxygen Species; U937 Cells | 2019 |
Cinnamaldehyde and eugenol attenuates collagen induced arthritis via reduction of free radicals and pro-inflammatory cytokines.
Topics: Acrolein; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arthritis, Experimental; Arthritis, Rheumatoid; Collagen Type II; Cytokines; Eugenol; Female; Free Radicals; Inflammation; Nitric Oxide; Oxidative Stress; Rats, Wistar; Tumor Necrosis Factor-alpha | 2019 |
Plant derived aporphinic alkaloid S-(+)-dicentrine induces antinociceptive effect in both acute and chronic inflammatory pain models: evidence for a role of TRPA1 channels.
Topics: Acetone; Acrolein; Acrylamides; Acute Disease; Alkaloids; Analgesics; Animals; Aporphines; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Chronic Pain; Cold Temperature; Freund's Adjuvant; Gene Expression; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Pain Measurement; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2013 |
Acrolein-induced inflammatory signaling in vascular smooth muscle cells requires activation of serum response factor (SRF) and NFκB.
Topics: Acrolein; Animals; Cell Survival; Cells, Cultured; Environmental Pollutants; Inflammation; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Rats; Serum Response Factor | 2013 |
Role of aldose reductase in the metabolism and detoxification of carnosine-acrolein conjugates.
Topics: Acetylcysteine; Acrolein; Aldehyde Reductase; Animals; Antioxidants; Carnosine; Humans; Inflammation; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Reperfusion Injury; Tissue Distribution | 2013 |
Acrolein involvement in sensory and behavioral hypersensitivity following spinal cord injury in the rat.
Topics: Acrolein; Animals; Behavior, Animal; Blotting, Western; Cold Temperature; DNA, Complementary; Electrophysiological Phenomena; Ganglia, Sensory; Hot Temperature; Hydralazine; Inflammation; Injections, Spinal; Lipid Peroxidation; Male; Neuralgia; Nociceptors; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reflex, Abnormal; RNA; Spinal Cord Injuries; TRPA1 Cation Channel; TRPC Cation Channels | 2014 |
Does drug-induced emphysema exist?
Topics: Acrolein; Animals; Cyclophosphamide; Diet; Emphysema; Histone Deacetylase Inhibitors; Humans; Inflammation; Lung; Signal Transduction; Vascular Endothelial Growth Factor A | 2013 |
Inflammatory and cytotoxic effects of acrolein, nicotine, acetylaldehyde and cigarette smoke extract on human nasal epithelial cells.
Topics: Acetaldehyde; Acrolein; Cell Death; Cells, Cultured; Epithelial Cells; Humans; Inflammation; Nasal Mucosa; Nicotiana; Nicotine; Smoke | 2014 |
Enhancement of the acrolein-induced production of reactive oxygen species and lung injury by GADD34.
Topics: Acetylcysteine; Acrolein; Animals; Apoptosis; Cells, Cultured; Endoplasmic Reticulum Stress; Epithelial Cells; Female; Inflammation; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering | 2015 |
Inhalation of the reactive aldehyde acrolein promotes antigen sensitization to ovalbumin and enhances neutrophilic inflammation.
Topics: Acrolein; Administration, Inhalation; Animals; Asthma; Cytokines; Immunoglobulin G; Inflammation; Lung; Male; Mice; Neutrophils; Ovalbumin | 2016 |
A Potential Role for Acrolein in Neutrophil-Mediated Chronic Inflammation.
Topics: Acrolein; Aminopeptidases; Chronic Disease; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Dose-Response Relationship, Drug; Humans; Inflammation; Leukotriene A4; Matrix Metalloproteinase 9; Neutrophils; Oligopeptides; Proline; Prolyl Oligopeptidases; Serine Endopeptidases | 2015 |
Influence of myeloperoxidase on colon tumor occurrence in inflamed versus non-inflamed colons of Apc(Min/+) mice.
Topics: Acrolein; Animals; Colitis; Colonic Neoplasms; Female; Gene Expression; Inflammation; Male; Mice; Mice, Transgenic; Oxidation-Reduction; Peroxidase; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Resorcinols; RNA, Small Interfering; Sodium Dodecyl Sulfate | 2015 |
Calcium carbonate hydrogel construct with cynnamaldehyde incorporated to control inflammation during surgical procedure.
Topics: Acrolein; Bacteria; Calcium Carbonate; Cell Death; Cell Survival; Drug Liberation; Fibroblasts; Gingiva; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogen-Ion Concentration; Inflammation; Materials Testing; Microbial Sensitivity Tests; Surgical Procedures, Operative | 2016 |
The tobacco smoke component acrolein induces glucocorticoid resistant gene expression via inhibition of histone deacetylase.
Topics: Acrolein; Cell Line, Tumor; Cells, Cultured; Drug Resistance; Gene Expression; Glucocorticoids; Glutathione; Histone Deacetylase 2; Humans; Hydrocortisone; Inflammation; Interleukin-8; Lipopolysaccharides; Lung; Macrophages; Pulmonary Disease, Chronic Obstructive; RNA, Messenger; Smoking; Tumor Necrosis Factor-alpha; Up-Regulation | 2016 |
[Changes of CD(4)(+) Foxp3+ regulatory T cells and CD(4)(+)IL-17+T cells in acrolein exposure rats].
Topics: Acrolein; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Forkhead Transcription Factors; Inflammation; Male; Rats; Rats, Wistar; T-Lymphocytes, Regulatory; Th17 Cells | 2015 |
Trans-Cinnamaldehyde, An Essential Oil in Cinnamon Powder, Ameliorates Cerebral Ischemia-Induced Brain Injury via Inhibition of Neuroinflammation Through Attenuation of iNOS, COX-2 Expression and NFκ-B Signaling Pathway.
Topics: Acrolein; Animals; Brain Injuries; Brain Ischemia; Cinnamomum zeylanicum; Cyclooxygenase 2; Disease Models, Animal; Gene Expression Regulation; Inflammation; Microglia; NF-kappa B; Nitric Oxide Synthase Type II | 2016 |
Albumin Cys34 adducted by acrolein as a marker of oxidative stress in ischemia-reperfusion injury during hepatectomy.
Topics: Acrolein; Albumins; Hepatectomy; Humans; Inflammation; Oxidative Stress; Reperfusion Injury | 2016 |
Selective inhibition of JAK2/STAT1 signaling and iNOS expression mediates the anti-inflammatory effects of coniferyl aldehyde.
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Carrageenan; Cell Line; Down-Regulation; Ear; Edema; Humans; Inflammation; Janus Kinase 2; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type II; Rats, Sprague-Dawley; RAW 264.7 Cells; Signal Transduction; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate | 2016 |
Cinnamaldehyde, Carvacrol and Organic Acids Affect Gene Expression of Selected Oxidative Stress and Inflammation Markers in IPEC-J2 Cells Exposed to Salmonella typhimurium.
Topics: Acrolein; Animals; Cymenes; Epithelial Cells; Gene Expression; Inflammation; Monoterpenes; Oxidative Stress; Salmonella typhimurium | 2016 |
Effect of sildenafil on acrolein-induced airway inflammation and mucus production in rats.
Topics: Acrolein; Analysis of Variance; Animals; Blotting, Western; Bronchoalveolar Lavage; Cyclic GMP; Cytokines; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Inflammation; Leukocytes; Lung Diseases; Male; Mucins; Nitric Oxide; Piperazines; Purines; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; Sildenafil Citrate; Sulfones | 2009 |
2'-Hydroxycinnamaldehyde targets low-density lipoprotein receptor-related protein-1 to inhibit lipopolysaccharide-induced microglial activation.
Topics: Acrolein; Anti-Inflammatory Agents; Antigens, CD; Blotting, Western; Cell Line; Cinnamomum aromaticum; Coculture Techniques; Cytokines; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Gene Expression; Humans; Immunoblotting; Inflammation; Lipopolysaccharides; Low Density Lipoprotein Receptor-Related Protein-1; Microglia; Neurons; Neuroprotective Agents; Plant Bark; Plant Extracts; Plant Stems; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels.
Topics: Acrolein; Analgesics; Animals; Calcium; Calcium Channels; Cells, Cultured; Disease Models, Animal; Freund's Adjuvant; Ganglia, Spinal; Gene Expression Regulation; Hemiterpenes; Humans; Inflammation; Membrane Potentials; Mice; Mice, Inbred ICR; Mice, Knockout; Nerve Tissue Proteins; Organophosphorus Compounds; Pain; Patch-Clamp Techniques; RNA, Messenger; RNA, Small Interfering; Sensory Receptor Cells; Transfection; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels | 2011 |
2'-Benzoyloxycinnamaldehyde inhibits nitric oxide production in lipopolysaccharide-stimulated RAW 264.7 cells via regulation of AP-1 pathway.
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Benzoates; Cell Line; Inflammation; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Transcription Factor AP-1 | 2012 |
Elevated neutrophil elastase and acrolein-protein adducts are associated with W256 regression.
Topics: Acrolein; Aldehydes; Animals; Cell Membrane; Disease Progression; Fatty Acids, Unsaturated; Granulocytes; Inflammation; Leukocyte Elastase; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Respiratory Burst; Tumor Microenvironment | 2012 |
Cigarette smoke triggers macrophage adhesion and activation: role of lipid peroxidation products and scavenger receptor.
Topics: Acrolein; Animals; Cell Adhesion; Chemotaxis; Humans; Inflammation; Lipid Peroxidation; Macrophages, Alveolar; Mice; Nicotiana; Oxidative Stress; Plants, Toxic; Proteins; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Receptors, Immunologic; Receptors, Scavenger; Smoke; Smoking | 2003 |
Acrolein impairs ATP binding cassette transporter A1-dependent cholesterol export from cells through site-specific modification of apolipoprotein A-I.
Topics: Acrolein; Adenosine Triphosphate; Amino Acid Sequence; Antibodies, Monoclonal; Apolipoprotein A-I; Arteries; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Blotting, Western; Cholesterol; Chromatography, Liquid; Crystallography, X-Ray; Electrophoresis, Polyacrylamide Gel; Humans; Immunohistochemistry; Inflammation; Lipid Peroxidation; Lipoproteins, HDL; Lysine; Mass Spectrometry; Models, Chemical; Molecular Sequence Data; Peptides; Peroxidase; Phospholipids; Protein Structure, Secondary; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Temperature; Threonine; Time Factors | 2005 |
Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain.
Topics: Acrolein; Animals; Ankyrins; Behavior, Animal; Calcium Channels; Cell Line; Electrophysiology; Enzyme Activation; Ganglia, Spinal; Gene Expression Regulation; Humans; Inflammation; Isothiocyanates; Male; Nerve Tissue Proteins; Pain; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, PAR-2; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels; Type C Phospholipases | 2007 |
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
Topics: Acrolein; Aldehydes; Ankyrins; Calcium Channels; Cell Line; Cloning, Molecular; Humans; Inflammation; Pain; Patch-Clamp Techniques; TRPA1 Cation Channel; TRPC Cation Channels | 2007 |
Reactive aldehyde modification of thioredoxin-1 activates early steps of inflammation and cell adhesion.
Topics: Acrolein; Aldehydes; Amino Acid Sequence; Animals; Aorta; Atherosclerosis; Cattle; Cell Adhesion; Cell Line; Endothelial Cells; Glutathione; Humans; Inflammation; JNK Mitogen-Activated Protein Kinases; Molecular Sequence Data; Monocytes; NF-kappa B; Oxidation-Reduction; Phosphorylation; Reactive Oxygen Species; Thioredoxins | 2007 |
Acrolein induces inflammatory response underlying endothelial dysfunction: a risk factor for atherosclerosis.
Topics: Acrolein; Air Pollution; Atherosclerosis; Cyclooxygenase 2; Dinoprostone; Endothelium, Vascular; Enzyme Induction; Humans; Inflammation; Lipid Peroxidation; Polyamines; Risk Factors; Smoking; Thioredoxin-Disulfide Reductase | 2008 |
Reduced toxicological activity of cigarette smoke by the addition of ammonia magnesium phosphate to the paper of an electrically heated cigarette: subchronic inhalation toxicology.
Topics: Acetaldehyde; Acrolein; Animals; Bronchoalveolar Lavage Fluid; Carbon Monoxide; Carboxyhemoglobin; Female; Formaldehyde; Hot Temperature; Inflammation; Magnesium Compounds; Male; Neutrophils; Nicotiana; Nicotine; Particle Size; Phosphates; Rats; Rats, Sprague-Dawley; Respiratory Tract Diseases; Smoke; Smoking | 2008 |
Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated
Topics: Acetaldehyde; Acrolein; Aldehydes; Amino Acids; Catalase; Chlorides; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Heme; Humans; Hydrogen Peroxide; Hydroxy Acids; Hypochlorous Acid; Inflammation; Lysine; Mass Spectrometry; Molecular Structure; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Serine; Threonine | 1997 |
Regulation of human airway mucins by acrolein and inflammatory mediators.
Topics: Acrolein; Carcinoma, Mucoepidermoid; Dinoprostone; Gene Expression Regulation; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Kinetics; Lung Neoplasms; Mucin 5AC; Mucin-5B; Mucins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Mechanisms of aldehyde-induced bronchial reactivity: role of airway epithelium.
Topics: Acetylcholine; Acrolein; Air Pollutants; Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Epithelium; Epoprostenol; Formaldehyde; Guinea Pigs; Hyperplasia; Inflammation; Leukocyte Count; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Phenothiazines; Phenylbutyrates; Prostaglandins F; SRS-A; Thromboxane B2; Time Factors | 1992 |