acrolein has been researched along with Disease Models, Animal in 107 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.87) | 18.7374 |
| 1990's | 5 (4.67) | 18.2507 |
| 2000's | 13 (12.15) | 29.6817 |
| 2010's | 62 (57.94) | 24.3611 |
| 2020's | 25 (23.36) | 2.80 |
| Authors | Studies |
|---|---|
| Bhadada, SK; Bhunia, RK; Bishnoi, M; Kaur, J; Khare, P; Kondepudi, KK; Kuhad, A; Kumar, V; Mahajan, N; Shafi, S | 1 |
| Chen, C; Han, Y; Hou, J; Hu, Y; Liu, Q; Lu, J; Mak, MS; Peng, W; Pi, R; Tsim, KWK; Wang, S; Xin, W; Yang, Y; Zhou, X; Zhu, Z | 1 |
| Albo, M; Chiang, G; Khimji, C; Lee, J; Lee, S; Malkmus, S; Yaksh, T | 1 |
| Deng, JH; Li, YL; Luo, JN; Qi, XM; Wang, GS; Wang, J; Zhang, XG | 1 |
| Chen, C; Chen, X; Lu, J; Peng, W; Pi, J; Pi, R; Wang, S; Xin, W; Yang, X; Yang, Y; Yao, L; Yin, W; Zhou, X; Zhu, Z | 1 |
| Le, TT; Urasaki, Y | 1 |
| Aihara, S; Hirashima, Y; Kitazono, T; Nakano, T; Torisu, K | 1 |
| Jiang, X; Peng, W; Pi, R; Wang, S; Yang, S; Zhou, S | 1 |
| Chen, H; Chen, J; Chen, X; Lin, J; Song, Z; Wu, Z; Yang, X; Zhao, R | 1 |
| Arıkök, AT; Bozkurt, H; Çelikoğlu, E; Gürer, B; Karakoç, A; Kertmen, H; Kuru Bektaşoğlu, P; Öztürk, ÖÇ | 1 |
| Mustafa, HN | 1 |
| Bellinghausen, I; Lucas, K; Maxeiner, J; Ose, R; Saloga, J; Schink, A; Schuster, P; Tu, J | 1 |
| Binda, NS; Borges, MH; Carobin, NV; Castro Junior, CJ; Ferreira, J; Gomez, MV; Kushmerick, C; Pinto Nagem, RA; Ribeiro, FM; Rita Pereira, EM; Santos, DC; Silva Júnior, CA; Silva, JF; Souza, JM | 1 |
| Chen, L; Li, YX; Liu, L; Mao, Y; Peng, X; Qu, S; Tian, J; Wang, Z | 1 |
| Chu, X; Deng, X; Liu, Y; Wang, T; Zhang, Y; Zhou, T; Zhou, Y | 1 |
| Boechat, SK; Neto, JGO; Oliveira, KJ; Pazos-Moura, CC; Romão, JS | 1 |
| Buday, T; Grendar, M; Plevkova, J; Sterusky, M | 1 |
| Singh, K | 1 |
| Chen, ML; Ge, YZ; Han, ZJ; Ma, KL; Pan, M; Shao, J; Wang, CZ; Wang, TM; Wu, DQ; Yan, GM | 1 |
| Chaurasia, SS; Fink, MK; Gupta, S; Hesemann, NP; Martin, LM; Mohan, RR; Rodier, JT; Sinha, NR; Sinha, PR | 1 |
| Dabzadeh, M; Forouzanfar, F; Ghaddaripouri, M; Hajinejad, M; Sahab-Negah, S | 1 |
| Chen, L; Lu, ZJ; Qu, SL; Wang, XY; Wen, XS; Yang, YF; Zuo, JP | 1 |
| Epifano, F; Fiorito, S; Genovese, S; Ibuka, T; Ideta, T; Kubota, M; Maruta, A; Miyazaki, T; Mizutani, T; Sakai, H; Shimizu, M; Shirakami, Y; Taddeo, VA; Tanaka, T | 1 |
| Cai, D; Chen, J; Chen, S; Jiang, L; Qin, J; Wang, J; Wu, J | 1 |
| Altuner, D; Bayram, R; Coban, TA; Dilber, M; Erhan, E; Salcan, I; Suleyman, B; Suleyman, H; Yazici, GN | 1 |
| Acosta, G; Andrews, KD; Cao, J; Dietrich, AD; Liu, Z; Lu, KH; Lungwitz, EA; Majumdar, S; Race, NS; Shekhar, A; Shi, R; Truitt, WA; Vega Alvarez, SM; Warner, TR | 1 |
| Choi, SH; Choi, YH; Hong, S; Hong, SH; Jeong, JW; Jin, CY; Kim, GY; Lee, H; Molagoda, IMN; Park, C | 1 |
| Akakın, D; Çelikoğlu, E; Demir, D; Gürer, B; Koyuncuoğlu, T; Kuru Bektaşoğlu, P; Peker Eyüboğlu, İ; Sucu, G; Yeğen, BÇ; Yüksel, M | 1 |
| Bergmayr, C; Buchleitner, S; Dvorak, Z; Fazekas, J; Jensen-Jarolim, E; Manzano-Szalai, K; Meitz, S; Moskovskich, A; Müller, MA; Neunkirchner, A; Roth, GA; Roth-Walter, F; Stremnitzer, C | 1 |
| Huang, HJ; Lin, AM; Lin, HC; Lo, YL; Wang, HT; Wang, YT; Zhao, WZ | 1 |
| Igarashi, K; Kashiwagi, K; Uemura, T | 1 |
| Hurley, JH; Johnson, PL; Kunkler, PE; Oxford, GS; Zhang, L | 1 |
| Higashi, K; Igarashi, K; Kashiwagi, K; Kitajima, M; Ko, K; Kogure, N; Sakamoto, A; Sugita, Y; Takao, K; Takayama, H; Terui, Y; Toida, T; Uemura, T; Watanabe, K | 1 |
| Jafari, M; Pham, HM; Schriner, SE; Sevrioukov, EA; Xu, A | 1 |
| Abou El-Ezz, D; El-Brairy, A; Kenawy, S; Maher, A; Sallam, N | 1 |
| Qu, S; Shen, Y; Wang, M; Wang, X; Yang, Y | 1 |
| Anand, P; Bhardwaj, M; Masand, N; Patil, VM | 1 |
| Aramsangtienchai, P; Chiranthanut, N; Kitwiwat, NT; Kongsamak, K; Mankhong, S; Srisook, K; Tongjurai, P | 1 |
| André, E; Arbiser, JL; Bomfim, MRQ; Calixto, JB; Fernandes, ES; Ferro, TAF; Gonzaga, LF; Machado, MCAM; Mendes, SJF; Monteiro-Neto, V; Pereira, DMS; Rodrigues, JFS; Souza, EB; Suarez, MAM | 1 |
| Guo, D; Jin, T; Shi, C; Xia, X; Yang, G; Yin, S; Zhang, C | 1 |
| Li, W; Liu, F; Niu, X; Zang, L; Zhao, J; Zhi, W | 1 |
| Hou, J; Liu, S; Wan, J; Wang, D; Wang, P; Yang, Y; Zhou, P | 1 |
| Cooper, B; Jannasch, A; Park, J; Shi, R; Tully, M; Walls, M; Zheng, L | 1 |
| Chiba, K; Hayashi, D; Igarashi, K; Ikuo, Y; Ishii, I; Kashiwagi, K; Kobayashi, K; Nishimura, K; Saiki, R; Toida, T | 1 |
| Costa, DL; Farraj, AK; Griggs, J; Haykal-Coates, N; Hazari, MS; Ledbetter, A; Winsett, DW | 1 |
| Habibovic, A; Hristova, M; Kasahara, D; Poynter, ME; Randall, MJ; Spiess, PC; van der Vliet, A | 1 |
| André, E; de Moura, JC; Gavioli, EC; Geppetti, P; Marone, IM; Materazzi, S; Minocci, D; Nassini, R; Noroes, MM; Preti, D; Rachetti, Vde P; Soares, BL | 1 |
| Gao, Z; Ji, K; Nissen, JC; Tsirka, SE | 1 |
| Chiou, TW; Harn, HJ; Hsieh, J; Lin, PC; Lin, SZ; Lin, YC; Liu, JW; Rajamani, K; Subeq, YM; Wen, TC | 1 |
| Taguchi, Y | 1 |
| Higashi, K; Igarashi, K; Nishimura, K; Saiki, R; Suabjakyong, P; Toida, T; Van Griensven, LJ | 1 |
| Bernardi, C; Cecconi, F; Cerù, MP; Cimini, A; Fanelli, F; Fracassi, A; Moreno, S; Porcellotti, S; Sepe, S | 1 |
| Chen, R; Dong, L; He, T; Li, L; Li, Y; Wen, Y; Zhang, C; Zhang, X; Zhang, Y; Zhao, J; Zheng, X; Zhu, X | 1 |
| Acosta, G; Park, J; Race, N; Shi, R; Vega-Alvarez, SM; Walls, MK; Zheng, L | 1 |
| Acosta, G; Cao, P; Chen, Z; Muratori, B; Park, J; Shi, R; Vega-Alvarez, S; Zheng, L | 1 |
| Ansari, NH; Ayadi, AE; Enkhbaatar, P; Finnerty, CC; Goswamy, J; Herndon, DN; Mifflin, R; Papaconstantinou, J; Sousse, L; Wang, CZ | 1 |
| Igarashi, K; Kashiwagi, K; Nakamura, M; Nishimura, K; Park, H; Saiki, R; Sakamoto, A; Terui, Y; Toida, T; Uemura, T | 1 |
| Bian, ZY; Hu, ZF; Liu, Y; Tang, QZ; Wu, QQ; Yang, L | 1 |
| Costa, SKP; da Costa, R; Fernandes, ES; Ferro, TAF; Grisotto, MAG; Mendes, SJF; Monteiro-Neto, V; Mouchrek, AQS; Nascimento, JLM; Pereira, DMS; Pereira, ICP; Pinheiro, AJMCR; Silva, BLR; Sousa, FIAB | 1 |
| Chen, YF; Huang, WS; Lee, MM; Leung, YM; Tsai, HY; Wang, YW; Wood, WG | 1 |
| Kaneko, A; Kono, T; Kubota, K; Mase, A; Matsushima, H; Miyano, K; Ohbuchi, K; Ohno, N; Tsuchiya, K; Uezono, Y; Yamamoto, M | 1 |
| Ahmad, N; Gautam, J; Karvande, A; Khedgikar, V; Kumar, P; Kushwaha, P; Maurya, R; Trivedi, R | 1 |
| Hu, T; Jia, ZX; Tie, C; Zhang, JL | 1 |
| Chen, Y; Fu, Y; Qin, Z; Xu, Y; Yang, P; Zhang, L; Zhang, Z | 1 |
| Aviram, M; Bar, H; Danin-Poleg, Y; Hayek, T; Kashi, Y; Korach-Rechtman, H; Rom, O | 1 |
| Cebak, JE; Hall, ED; Hill, RL; Singh, IN; Wang, JA | 1 |
| Bi, L; Cao, W; Wang, S; Xie, Y; Yang, Q; Zhang, M; Zhao, H; Zhou, F | 1 |
| Campos, AR; da Costa, FN; de Vasconcellos Abdon, AP; Duailibe, MA; Melo, LT; Pessoa, LM; Vieira-Neto, AE | 1 |
| Amalaradjou, MA; Mooyottu, S; Muyyarikkandy, MS; Narayanan, A; Venkitanarayanan, K | 1 |
| DeBerry, JJ; Dewberry, LS; Sorge, RE; Taylor, JC; Totsch, SK; Watts, SA; Yessick, LR | 1 |
| Shi, R; Tian, R | 1 |
| Bjorling, DE; Guerios, SD; Merriam, FV; Wang, ZY | 1 |
| Igarashi, K; Ishii, I; Kashiwagi, K; Nishimura, K; Okuyama, S; Omura, T; Saiki, R | 1 |
| Belvisi, MG; Birrell, MA; Faruqi, S; Freund-Michel, V; Grace, M; Hele, DJ; Maher, SA; Morice, AH; Sadofsky, L | 1 |
| Abe, S; Arai, R; Inoue, S; Ishibashi, H; Sagawa, T; Taguchi, Y; Takizawa, T; Yamaguchi, H | 1 |
| Beckman, E; Borchers, MT; Deshmukh, H; Leikauf, GD; Medvedovic, M; Sartor, M; Wesselkamper, SC | 1 |
| Aizawa, N; Igawa, Y; Nishizawa, O; Wyndaele, JJ | 1 |
| Igarashi, K; Ikeguchi, Y; Ishii, I; Kashiwagi, K; Kojima, S; Nishimura, K; Park, H; Pegg, AE; Saiki, R; Tatsukawa, H; Toida, T; Yoshida, M | 1 |
| Bein, K; Berndt, A; Brant, KA; Concel, VJ; Di, YP; Dietsch, M; Dopico, RA; Ganguly, K; Jang, AS; Kaminski, N; Leikauf, GD; Li, Q; Liu, P; Medvedovic, M; Pope-Varsalona, H; Prows, DR; Vuga, LJ; You, M | 1 |
| Córdova, MM; Pizzolatti, MG; Ruani, AP; Santos, AR; Silva, MD; Werner, MF | 1 |
| Igarashi, K; Kashiwagi, K | 2 |
| Bang, S; Cho, H; Hwang, SW; Yang, TJ; Yoo, S | 1 |
| Andrade, EL; Bento, AF; Calixto, JB; Dias, MA; Forner, S; Koepp, J; Leal, PC; Leite, DF | 1 |
| Abe, S; Arai, R; Hayama, K; Okada, M; Sagawa, T; Taguchi, Y | 1 |
| Maier, CS; Stevens, JF; Wu, J | 1 |
| Bae, KH; Chang, KC; Hwa, JS; Jin, YC; Kim, HJ; Kim, YM; Kim, YS; Ko, YS; Lee, JH; Lee, YS; Ngoc, TM; Shi, LY | 1 |
| Ito, M; Sawada, Y; Tankam, JM | 1 |
| Kumar, S; Sharma, S; Vasudeva, N | 1 |
| Gong, YJ; Liang, YH; Liu, J; Tu, L; Wei, M; Zhang, JH | 1 |
| Chang, H; Hong, SH; Ismail, IA; Kang, HS; Kim, HS; Kim, NH; Kwon, BM; Lee, CW; Lee, HJ; Yook, JI; Yun, J | 1 |
| Chung, H; Kang, SG; Kim, YT; Kwon, BM; Lee, JJ; Park, JK; Yoo, YD; Yu, YS | 1 |
| Peasley, MA; Shi, R | 1 |
| Campochiaro, PA; Dong, A; Peng, YW; Petters, RM; Shen, J; Wong, F; Yang, X | 1 |
| Murata, T; Nagai, H; Okamoto, N; Tamai, H; Tanaka, H | 1 |
| Baker, G; Khan, MA; Moskal, JR; Tanay, VA; Todd, KG; Wood, PL | 1 |
| Batista, CK; Brito, GA; Cunha, FQ; Leitão, BT; Ribeiro, RA; Souza, ML | 1 |
| Barber, DS; Gavin, T; LoPachin, RM | 1 |
| Almeida, PR; Baltazar, F; Macedo, FY; Mota, JM; Mourão, LC; Ribeiro, RA; Schmitt, FC | 1 |
| Egle, JL; Green, MA | 1 |
| Morris, ME; Springate, JE; Zamlauski-Tucker, MJ | 1 |
| Basketter, DA; Gerberick, GF | 1 |
| Boucher, M; Codron, JP; Coudore, F; Eschalier, A; Kemeny, JL; Meen, M | 1 |
| Allenby, CF; Basketter, DA | 1 |
| Breitenstein, MJ; Susten, AS | 1 |
| Beeley, JM; Bell, S; Buchanan, JD; Clark, RJ; Critchley, JA; Edginton, JA; Spurlock, MS; Summerfield, M | 1 |
| Anvaer, LP; Babenko, EIa; Fediakina, RP; Malinina, EM; Shcheglova, TS | 1 |
4 review(s) available for acrolein and Disease Models, Animal
| Article | Year |
|---|---|
Natural Cinnamaldehyde and Its Derivatives Ameliorate Neuroinflammatory Pathways in Neurodegenerative Diseases.
Topics: Acrolein; Animals; Disease Models, Animal; Disease Progression; Humans; Inflammation; Neurodegenerative Diseases; Neuroprotective Agents | 2020 |
[Oral health care by utilizing food function].
Topics: Acrolein; Animals; Candida albicans; Candidiasis, Oral; Cinnamomum aromaticum; Disease Models, Animal; Drug Resistance, Fungal; Humans; Methylcellulose; Mice; Plant Extracts; Plants, Medicinal; Spices; Syzygium | 2014 |
Protein-conjugated acrolein as a biochemical marker of brain infarction.
Topics: Acrolein; Animals; Biomarkers; Brain Infarction; C-Reactive Protein; Disease Models, Animal; Humans; Interleukin-6; Mice; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Reactive Oxygen Species; Renal Insufficiency; ROC Curve; Sensitivity and Specificity; Sjogren's Syndrome; Stroke; Thrombosis | 2011 |
Molecular mechanisms of the conjugated alpha,beta-unsaturated carbonyl derivatives: relevance to neurotoxicity and neurodegenerative diseases.
Topics: Acrolein; Acrylamide; Aldehydes; Alzheimer Disease; Animals; Brain; Disease Models, Animal; DNA Adducts; DNA Damage; Humans; Neurotoxicity Syndromes | 2008 |
1 trial(s) available for acrolein and Disease Models, Animal
| Article | Year |
|---|---|
Studies of the quenching phenomenon in delayed contact hypersensitivity reactions.
Topics: Acrolein; Adult; Aged; Animals; Dermatitis, Contact; Disease Models, Animal; Eugenol; Female; Guinea Pigs; Humans; Male; Middle Aged; Patch Tests; Perfume | 1991 |
102 other study(ies) available for acrolein and Disease Models, Animal
| Article | Year |
|---|---|
Combination of TRP channel dietary agonists induces energy expending and glucose utilizing phenotype in HFD-fed mice.
Topics: Acrolein; Animals; Capsaicin; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Menthol; Mice; Mice, Inbred C57BL; Phenotype; Transient Receptor Potential Channels | 2022 |
Acrolein, an endogenous aldehyde induces Alzheimer's disease-like pathologies in mice: A new sporadic AD animal model.
Topics: Acrolein; Actin Depolymerizing Factors; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Hippocampus; Male; Mice, Inbred C57BL; Neurons; Olfactory Bulb; Peptide Fragments; Phosphorylation; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Synapsins; tau Proteins | 2022 |
Repeated Low-Dose Acrolein Triggers Irreversible Lamina Propria Edema in Urinary Bladder, Transient Voiding Behavior and Widening of Eyes to Mechanical Stimuli.
Topics: Acrolein; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Cyclophosphamide; Cystitis; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Hemorrhage; Humans; Mice; Mucous Membrane; Muscle, Smooth; Urinary Bladder | 2021 |
Effect of Cinnamaldehyde on C. albicans cell wall and (1,3)- β - D-glucans in vivo.
Topics: Acrolein; Animals; Candida albicans; Candidiasis; Cell Wall; Disease Models, Animal; Glucans; Immunocompromised Host; Male; Mice; Mice, Inbred BALB C | 2022 |
Acrolein, an endogenous aldehyde induces synaptic dysfunction in vitro and in vivo: Involvement of RhoA/ROCK2 pathway.
Topics: Acrolein; Aldehydes; Alzheimer Disease; Animals; Disease Models, Animal; Hippocampus; Humans; Mice; rho-Associated Kinases; rhoA GTP-Binding Protein | 2022 |
A Composition of Phytonutrients for Glycemic and Weight Management.
Topics: Acrolein; Animals; Berberine; Blood Glucose; Curcumin; Diabetes Mellitus; Disease Models, Animal; Fatty Acids; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Lipids; Mice; Obesity; Phytochemicals; Weight Gain | 2022 |
Acrolein produced during acute kidney injury promotes tubular cell death.
Topics: Acrolein; Acute Kidney Injury; Animals; Cell Death; Cysteamine; Disease Models, Animal; Humans; Hypoxia; Ischemia; Kidney; Mice; Oxygen; Polyamines; Reperfusion Injury; RNA, Messenger | 2023 |
Acrolein Induces Retinal Abnormalities of Alzheimer's Disease in Mice.
Topics: Acrolein; Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Mice; Retina | 2023 |
Trans-cinnamaldehyde shows anti-depression effect in the forced swimming test and possible involvement of the endocannabinoid system.
Topics: Acrolein; Animals; Antidepressive Agents; Depression; Depressive Disorder; Disease Models, Animal; Endocannabinoids; Male; Mice, Inbred BALB C; Swimming | 2019 |
The effects of Cinnamaldehyde on early brain injury and cerebral vasospasm following experimental subarachnoid hemorrhage in rabbits.
Topics: Acrolein; Animals; Basilar Artery; Disease Models, Animal; Hippocampus; Male; Nerve Degeneration; Neuroprotective Agents; Rabbits; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2019 |
Neuro-amelioration of cinnamaldehyde in aluminum-induced Alzheimer's disease rat model.
Topics: Acrolein; Aluminum; Aluminum Chloride; Aluminum Compounds; Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Hippocampus; Male; Memory; Neurofibrillary Tangles; Neuroprotective Agents; Oxidative Stress; Plaque, Amyloid; Rats, Wistar | 2020 |
Cinnamon extract inhibits allergen-specific immune responses in human and murine allergy models.
Topics: Acrolein; Animals; Basophils; Betula; CD4-Positive T-Lymphocytes; Cell Proliferation; Cinnamomum zeylanicum; Coculture Techniques; Cymenes; Cytokines; Dendritic Cells; Dermatitis, Atopic; Disease Models, Animal; Humans; Hypersensitivity, Immediate; Mice; Mice, Inbred BALB C; Ovalbumin; Plant Extracts; Plethysmography, Whole Body; Poaceae; Pollen; Respiratory Hypersensitivity; Rhinitis, Allergic, Seasonal | 2020 |
Phoneutria toxin PnTx3-5 inhibits TRPV1 channel with antinociceptive action in an orofacial pain model.
Topics: Acrolein; Anilides; Animals; Calcium; Calcium Signaling; Capsaicin; Cinnamates; Disease Models, Animal; Facial Pain; Glutamic Acid; HEK293 Cells; Humans; Inhibitory Concentration 50; Male; Neuropeptides; Nociception; Patch-Clamp Techniques; Rats; Sensory System Agents; Transfection; Trigeminal Ganglion; TRPA1 Cation Channel; TRPV Cation Channels | 2020 |
Cinnamaldehyde inhibits Candida albicans growth by causing apoptosis and its treatment on vulvovaginal candidiasis and oropharyngeal candidiasis.
Topics: Acrolein; Animals; Antifungal Agents; Apoptosis; Calcium; Candida albicans; Candidiasis, Oral; Candidiasis, Vulvovaginal; Cytochromes c; Disease Models, Animal; Female; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mitochondria; Reactive Oxygen Species | 2019 |
Cinnamaldehyde inhibits type three secretion system in Salmonella enterica serovar Typhimurium by affecting the expression of key effector proteins.
Topics: Acrolein; Animals; Anti-Bacterial Agents; Disease Models, Animal; Gene Expression Regulation, Bacterial; HeLa Cells; Humans; Mice; Salmonella Infections; Salmonella typhimurium; Type III Secretion Systems | 2019 |
Treatment with cinnamaldehyde reduces the visceral adiposity and regulates lipid metabolism, autophagy and endoplasmic reticulum stress in the liver of a rat model of early obesity.
Topics: Acrolein; Adiposity; Animals; Autophagy; Body Weight; Disease Models, Animal; Endoplasmic Reticulum Stress; Hyperphagia; Insulin Resistance; Intra-Abdominal Fat; Lipid Metabolism; Lipids; Liver; Male; Obesity; Rats; Rats, Wistar; Triglycerides | 2020 |
Female Guinea Pig Model for Cough Studies and Its Response to Most Common Tussive Substances.
Topics: Acrolein; Animals; Capsaicin; Citric Acid; Cough; Disease Models, Animal; Female; Guinea Pigs; Male; Sex Characteristics | 2020 |
Evaluation of antifungal activity of cinnamaldehyde against Cryptococcus neoformans var. grubii.
Topics: Acrolein; Animals; Antifungal Agents; Brain; Cryptococcosis; Cryptococcus neoformans; Disease Models, Animal; Drug Resistance, Fungal; Liver; Lung; Mice; Microbial Sensitivity Tests; Mycoses; Survival Analysis | 2020 |
[Therapeutic effect of cinnamaldehyde on ulcerative colitis in mice induced by dextran sulfate sodium with Candida albicans colonization and its effect on dectin-1/TLRs/NF-κB signaling pathway].
Topics: Acrolein; Animals; Candida albicans; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Lectins, C-Type; Mice; NF-kappa B; Signal Transduction | 2020 |
A rabbit model for evaluating ocular damage from acrolein toxicity in vivo.
Topics: Acrolein; Animals; Chemical Warfare Agents; Cornea; Corneal Injuries; Disease Models, Animal; Rabbits | 2020 |
Suppression of Th17 cell differentiation via sphingosine-1-phosphate receptor 2 by cinnamaldehyde can ameliorate ulcerative colitis.
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Cell Differentiation; Colitis, Ulcerative; Colon; Cytokines; Disease Models, Animal; Inflammation Mediators; Intestinal Mucosa; Male; Mice, Inbred BALB C; Phenotype; RNA, Long Noncoding; Signal Transduction; Sphingosine-1-Phosphate Receptors; Th17 Cells | 2021 |
Novel FXR agonist nelumal A suppresses colitis and inflammation-related colorectal carcinogenesis.
Topics: Acrolein; Animals; Azoxymethane; Carcinogenesis; Carcinogens; Colitis; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred A; RNA-Binding Proteins | 2021 |
Coniferaldehyde prevents articular cartilage destruction in a murine model via Nrf2/HO‑1 pathway.
Topics: Acrolein; Animals; Cartilage, Articular; Cells, Cultured; Disease Models, Animal; Heme Oxygenase-1; Membrane Proteins; Mice; NF-E2-Related Factor 2; Osteoarthritis; Signal Transduction | 2021 |
Protective effect of lutein against acrolein-induced ototoxicity in rats.
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Inflammation Mediators; Lutein; Male; Ototoxicity; Oxidative Stress; Rats, Wistar; Vestibulocochlear Nerve; Vestibulocochlear Nerve Diseases | 2021 |
Psychosocial impairment following mild blast-induced traumatic brain injury in rats.
Topics: Acetylcysteine; Acrolein; Animals; Blast Injuries; Brain; Brain Concussion; Brain Injuries; Disease Models, Animal; Magnetic Resonance Imaging; Male; Prefrontal Cortex; Psychosocial Functioning; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 2021 |
Inhibition of Lipopolysaccharide-Induced Inflammatory and Oxidative Responses by
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Disease Models, Animal; Drug Evaluation, Preclinical; Inflammation; Lipopolysaccharides; Mice; Myoblasts; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Toll-Like Receptor 4; Zebrafish | 2021 |
Neuroprotective Effect of Cinnamaldehyde on Secondary Brain Injury After Traumatic Brain Injury in a Rat Model.
Topics: Acrolein; Animals; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Male; Neuroprotective Agents; Rats; Rats, Wistar; Reactive Oxygen Species | 2021 |
Janus-faced Acrolein prevents allergy but accelerates tumor growth by promoting immunoregulatory Foxp3+ cells: Mouse model for passive respiratory exposure.
Topics: Acrolein; Allergens; Animals; Antibody Formation; Cytokines; Disease Models, Animal; Forkhead Transcription Factors; Hypersensitivity; Immunologic Factors; Lung; Mice; Neoplasms; NF-kappa B; Receptors, Aryl Hydrocarbon; Resveratrol; Signal Transduction; Stilbenes; T-Lymphocytes, Regulatory | 2017 |
Acrolein acts as a neurotoxin in the nigrostriatal dopaminergic system of rat: involvement of α-synuclein aggregation and programmed cell death.
Topics: Acrolein; alpha-Synuclein; Animals; Cell Death; Disease Models, Animal; Dopaminergic Neurons; Encephalitis; Male; Oxidative Stress; Parkinsonian Disorders; Protein Aggregation, Pathological; Rats, Sprague-Dawley; Substantia Nigra | 2017 |
Acrolein: An Effective Biomarker for Tissue Damage Produced from Polyamines.
Topics: Acrolein; Animals; Biomarkers; Calcium; Cell Line; Disease Models, Animal; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Hydrogen Peroxide; Male; Mice; Polyamines; Reactive Oxygen Species; Spermine; Stroke; Thrombosis | 2018 |
Induction of chronic migraine phenotypes in a rat model after environmental irritant exposure.
Topics: Acrolein; Analysis of Variance; Animals; Chronic Disease; Disease Models, Animal; Exploratory Behavior; Hyperalgesia; Irritants; Laser-Doppler Flowmetry; Male; Migraine Disorders; Physical Stimulation; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Smell; Sumatriptan; Trigeminal Nuclei; Vasoconstrictor Agents | 2018 |
Protective Effects of Brain Infarction by
Topics: Acetylcysteine; Acrolein; Animals; Brain; Brain Infarction; Cell Line, Tumor; Disease Models, Animal; Glutathione; Mice; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species | 2018 |
Cinnamaldehyde Improves Lifespan and Healthspan in
Topics: Acrolein; Alzheimer Disease; Animals; Disease Models, Animal; Drosophila melanogaster; Longevity; tau Proteins | 2018 |
Trans-cinnamaldehyde Modulates Hippocampal Nrf2 Factor and Inhibits Amyloid Beta Aggregation in LPS-Induced Neuroinflammation Mouse Model.
Topics: Acrolein; Amyloid beta-Peptides; Animals; Disease Models, Animal; Hippocampus; Inflammation; Lipopolysaccharides; Male; Maze Learning; Mice; NF-E2-Related Factor 2; Protein Aggregation, Pathological; Random Allocation | 2018 |
Suppression of miR-21 and miR-155 of macrophage by cinnamaldehyde ameliorates ulcerative colitis.
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Antigens, Differentiation; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Humans; Inflammasomes; Inflammation; Inflammation Mediators; Interleukin-10; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; MicroRNAs; NLR Family, Pyrin Domain-Containing 3 Protein; RAW 264.7 Cells; Reactive Oxygen Species; U937 Cells | 2019 |
Cinnamaldehyde Analogs: Docking Based Optimization, COX-2 Inhibitory In Vivo and In Vitro Studies.
Topics: Acrolein; Animals; Carrageenan; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Drug Development; Edema; Enzyme Assays; Female; Humans; Insecta; Male; Membrane Proteins; Mice; Molecular Docking Simulation; Recombinant Proteins; Structure-Activity Relationship | 2020 |
Anti-inflammatory effect of trans-4-methoxycinnamaldehyde from Etlingera pavieana in LPS-stimulated macrophages mediated through inactivation of NF-κB and JNK/c-Jun signaling pathways and in rat models of acute inflammation.
Topics: Acrolein; Alkynes; Animals; Anti-Inflammatory Agents; Carrageenan; Cyclooxygenase 2; Disease Models, Animal; Edema; Endotoxins; Humans; JNK Mitogen-Activated Protein Kinases; Macrophage Activation; Macrophages; Male; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-jun; Rats, Sprague-Dawley; RAW 264.7 Cells; Rhizome; Signal Transduction; Zingiberaceae | 2019 |
Topical Application of Cinnamaldehyde Promotes Faster Healing of Skin Wounds Infected with
Topics: Acrolein; Animals; Anti-Infective Agents; Biofilms; Disease Models, Animal; Female; Interleukin-17; Mice; Pseudomonas aeruginosa; Pseudomonas Infections; Skin; TRPA1 Cation Channel; Vascular Endothelial Growth Factor A; Wound Healing | 2019 |
trans-Cinnamaldehyde mitigated intestinal inflammation induced by Cronobacter sakazakii in newborn mice.
Topics: Acrolein; Animals; Animals, Newborn; Cronobacter sakazakii; Disease Models, Animal; Enterocolitis, Necrotizing; Female; Humans; Interleukin-6; Intestines; Isomerism; Male; Mice; Tumor Necrosis Factor-alpha | 2019 |
Cinnamaldehyde attenuates atherosclerosis via targeting the IκB/NF-κB signaling pathway in high fat diet-induced ApoE
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Cholesterol, HDL; Cholesterol, LDL; Cinnamomum aromaticum; Cytokines; Diet, High-Fat; Disease Models, Animal; I-kappa B Proteins; Male; Malondialdehyde; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Phosphorylation; Plant Extracts; Plaque, Atherosclerotic; Signal Transduction; Transcription Factor RelA | 2019 |
Cinnamaldehyde Ameliorates High-Glucose-Induced Oxidative Stress and Cardiomyocyte Injury Through Transient Receptor Potential Ankyrin 1.
Topics: Acrolein; Animals; Antioxidants; Apoptosis; Cardiotoxicity; Cell Line; Diabetic Cardiomyopathies; Disease Models, Animal; Fibrosis; Glucose; Mice, Inbred C57BL; Myocytes, Cardiac; NF-E2-Related Factor 2; Oxidative Stress; Rats; Signal Transduction; TRPA1 Cation Channel | 2019 |
Determination of urine 3-HPMA, a stable acrolein metabolite in a rat model of spinal cord injury.
Topics: Acetylcysteine; Acrolein; Animals; Biomarkers; Chromatography, Liquid; Disease Models, Animal; Immunoblotting; Male; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tandem Mass Spectrometry | 2013 |
Acrolein stimulates the synthesis of IL-6 and C-reactive protein (CRP) in thrombosis model mice and cultured cells.
Topics: Acrolein; Animals; Brain Neoplasms; C-Reactive Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; Cerebral Infarction; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; Macrophages; Mice; Neuroblastoma; Thrombosis; Transcription Factor RelA | 2013 |
A single exposure to acrolein desensitizes baroreflex responsiveness and increases cardiac arrhythmias in normotensive and hypertensive rats.
Topics: Acrolein; Air Pollutants; Animals; Arrhythmias, Cardiac; Baroreflex; Blood Pressure; Blood Pressure Determination; Disease Models, Animal; Electrocardiography, Ambulatory; Heart Rate; Hypertension; Male; Plethysmography, Whole Body; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Respiration; Risk Assessment; Telemetry; Time Factors | 2014 |
Acrolein exposure suppresses antigen-induced pulmonary inflammation.
Topics: Acrolein; Animals; Asthma; Disease Models, Animal; Glutathione; Immunoglobulin G; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Ovalbumin; Signal Transduction; Sulfhydryl Compounds; Th1-Th2 Balance; Transcription Factors | 2013 |
The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice.
Topics: Acetanilides; Acrolein; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Depression; Diazepam; Disease Models, Animal; Male; Mice, Knockout; Nortriptyline; Purines; Signal Transduction; Swimming; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2014 |
The experimental autoimmune encephalomyelitis disease course is modulated by nicotine and other cigarette smoke components.
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Cells, Cultured; Demyelinating Diseases; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Nicotiana; Nicotine; Peptides; Smoke; Smoking | 2014 |
The antisenescence effect of trans-cinnamaldehyde on adipose-derived stem cells.
Topics: Acrolein; Adipose Tissue; Alanine Transaminase; alpha-Fetoproteins; Animals; Aspartate Aminotransferases; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cellular Senescence; Disease Models, Animal; Female; HEK293 Cells; Humans; Hydrogen Peroxide; Isomerism; Liver; Liver Cirrhosis; Middle Aged; Rats; Rats, Wistar; Sirtuin 1; Stem Cell Transplantation; Stem Cells; Telomerase; Transcriptome | 2015 |
Polyphenol extract from Phellinus igniarius protects against acrolein toxicity in vitro and provides protection in a mouse stroke model.
Topics: Acrolein; Animals; Antioxidants; Basidiomycota; Cell Line; Disease Models, Animal; Environmental Pollutants; Hydrogen Peroxide; Male; Mice; Polyphenols; Protective Agents; Stroke | 2015 |
Oxidative Stress during the Progression of β-Amyloid Pathology in the Neocortex of the Tg2576 Mouse Model of Alzheimer's Disease.
Topics: Acrolein; Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; ATP-Binding Cassette Transporters; Disease Models, Animal; Down-Regulation; Female; Genotype; Glial Fibrillary Acidic Protein; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Neocortex; Nerve Tissue Proteins; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Peroxisomes; PPAR alpha; Superoxide Dismutase; Superoxide Dismutase-1; Transcription Factors | 2015 |
Cinnamaldehyde inhibits inflammation and brain damage in a mouse model of permanent cerebral ischaemia.
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Brain; Chemokine CCL2; Disease Models, Animal; E-Selectin; Infarction, Middle Cerebral Artery; Interleukin-1beta; Male; Mice; Neuroprotective Agents; NF-kappa B; RNA, Messenger; TNF Receptor-Associated Factor 6; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Water | 2015 |
Structural and biochemical abnormalities in the absence of acute deficits in mild primary blast-induced head trauma.
Topics: Acrolein; Animals; Blast Injuries; Blood-Brain Barrier; Brain Injuries; Disease Models, Animal; Memory, Short-Term; Motor Activity; Oxidative Stress; Rats | 2016 |
Acrolein contributes to TRPA1 up-regulation in peripheral and central sensory hypersensitivity following spinal cord injury.
Topics: Acetylcysteine; Acrolein; Animals; Disease Models, Animal; Ganglia, Spinal; Hydralazine; Hyperalgesia; Locomotion; Male; Neuralgia; Pain Threshold; Rats; Rats, Sprague-Dawley; Skin; Spinal Cord; Spinal Cord Injuries; TRPA1 Cation Channel; TRPC Cation Channels; Up-Regulation; Vasodilator Agents | 2015 |
Topically applied metal chelator reduces thermal injury progression in a rat model of brass comb burn.
Topics: Acrolein; Administration, Cutaneous; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Animals; Burns; Chelating Agents; Copper; Dimethyl Sulfoxide; Disease Models, Animal; Edetic Acid; Immunohistochemistry; Malondialdehyde; Mitochondrial Proteins; Oxidative Stress; Permeability; Rats; Retinal Dehydrogenase; Skin; Sulfones; Trauma Severity Indices; Zinc | 2015 |
Toxic acrolein production due to Ca(2+) influx by the NMDA receptor during stroke.
Topics: Acrolein; Animals; Blotting, Western; Brain; Brain Infarction; Calcium; Cell Line, Tumor; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate | 2016 |
Cinnamaldehyde attenuates pressure overload-induced cardiac hypertrophy.
Topics: Acrolein; Animals; Cytoprotection; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Hemodynamics; Hypertrophy, Left Ventricular; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Protein Kinase Inhibitors; Signal Transduction; Ventricular Function, Left | 2015 |
Cinnamaldehyde modulates LPS-induced systemic inflammatory response syndrome through TRPA1-dependent and independent mechanisms.
Topics: Acetanilides; Acrolein; Animals; Cell Movement; Cinnamomum zeylanicum; Disease Models, Animal; Female; Interleukin-10; Interleukin-1beta; Lipopolysaccharides; Macrophages; Mice; Pregnancy; Purines; Systemic Inflammatory Response Syndrome; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2016 |
Trans-Cinnamaldehyde, An Essential Oil in Cinnamon Powder, Ameliorates Cerebral Ischemia-Induced Brain Injury via Inhibition of Neuroinflammation Through Attenuation of iNOS, COX-2 Expression and NFκ-B Signaling Pathway.
Topics: Acrolein; Animals; Brain Injuries; Brain Ischemia; Cinnamomum zeylanicum; Cyclooxygenase 2; Disease Models, Animal; Gene Expression Regulation; Inflammation; Microglia; NF-kappa B; Nitric Oxide Synthase Type II | 2016 |
Transient receptor potential ankyrin 1 agonists improve intestinal transit in a murine model of postoperative ileus.
Topics: Acrolein; Amides; Animals; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Transit; Ileus; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Naphthoquinones; Organ Culture Techniques; TRPA1 Cation Channel | 2016 |
A neoflavonoid dalsissooal isolated from heartwood of Dalbergia sissoo Roxb. has bone forming effects in mice model for osteoporosis.
Topics: Acrolein; Animals; Calcification, Physiologic; Cancellous Bone; Cell Differentiation; Dalbergia; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogens; Female; Flavonoids; Gene Expression Regulation; Mice; Osteoblasts; Osteocalcin; Osteogenesis; Osteoporosis; Ovariectomy; Phenols; Plant Leaves; Uterus | 2016 |
Derivatization Strategy for the Comprehensive Characterization of Endogenous Fatty Aldehydes Using HPLC-Multiple Reaction Monitoring.
Topics: Acrolein; Aldehydes; Animals; Biomarkers; Brain; Chromatography, High Pressure Liquid; Dementia; Deuterium; Discriminant Analysis; Disease Models, Animal; Fatty Acids; Limit of Detection; Male; Principal Component Analysis; Rats; Rats, Wistar; Triazines | 2016 |
Trans-cinnamaldehyde improves memory impairment by blocking microglial activation through the destabilization of iNOS mRNA in mice challenged with lipopolysaccharide.
Topics: Acrolein; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Enzyme Stability; Escherichia coli; Lipopolysaccharides; Male; MAP Kinase Signaling System; Memory Disorders; Mice, Inbred ICR; Microglia; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Nootropic Agents; Random Allocation; Rats, Sprague-Dawley; RNA, Messenger | 2016 |
Acrolein increases macrophage atherogenicity in association with gut microbiota remodeling in atherosclerotic mice: protective role for the polyphenol-rich pomegranate juice.
Topics: Acrolein; Animals; Apolipoproteins E; Atherosclerosis; Cell Line; Disease Models, Animal; Gastrointestinal Microbiome; Lipid Metabolism; Lythraceae; Macrophages; Macrophages, Peritoneal; Male; Mice; Mice, Knockout; Oxidative Stress; Polyphenols | 2017 |
Phenelzine Protects Brain Mitochondrial Function In Vitro and In Vivo following Traumatic Brain Injury by Scavenging the Reactive Carbonyls 4-Hydroxynonenal and Acrolein Leading to Cortical Histological Neuroprotection.
Topics: Acrolein; Aldehydes; Animals; Brain Injuries, Traumatic; Cerebral Cortex; Disease Models, Animal; Male; Mitochondria; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Phenelzine; Rats; Rats, Sprague-Dawley | 2017 |
Cinnamaldehyde ameliorates LPS-induced cardiac dysfunction via TLR4-NOX4 pathway: The regulation of autophagy and ROS production.
Topics: Acrolein; Animals; Autophagy; Biomarkers; Cytokines; Disease Models, Animal; Echocardiography; Inflammation Mediators; Lipopolysaccharides; Male; MAP Kinase Signaling System; Myocytes, Cardiac; NADPH Oxidase 4; NADPH Oxidases; Rats; Reactive Oxygen Species; RNA Interference; Signal Transduction; Toll-Like Receptor 4; Ventricular Dysfunction | 2016 |
(-)-α-Bisabolol reduces orofacial nociceptive behavior in rodents.
Topics: Acrolein; Administration, Oral; Administration, Topical; Analgesics; Animals; Behavior, Animal; Binding Sites; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Compounding; Facial Pain; Formaldehyde; Male; Mice; Molecular Docking Simulation; Monocyclic Sesquiterpenes; Nociception; Nociceptive Pain; Protein Binding; Protein Conformation; Rats, Wistar; Sesquiterpenes; Temporomandibular Joint; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels | 2017 |
Oral supplementation of trans-cinnamaldehyde reduces uropathogenic Escherichia coli colonization in a mouse model.
Topics: Acrolein; Animals; Anti-Bacterial Agents; Disease Models, Animal; Escherichia coli Infections; Female; Humans; Mice; Mice, Inbred C57BL; Urinary Tract Infections; Uropathogenic Escherichia coli | 2017 |
A novel zebrafish-based model of nociception.
Topics: Acetic Acid; Acrolein; Analgesics, Opioid; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Histamine; Histamine Agonists; Male; Morphine; Mustard Plant; Naloxone; Narcotic Antagonists; Nociception; Pain; Plant Oils; Swimming; Zebrafish | 2017 |
Dimercaprol is an acrolein scavenger that mitigates acrolein-mediated PC-12 cells toxicity and reduces acrolein in rat following spinal cord injury.
Topics: Acrolein; Animals; Body Weight; Cell Death; Dimercaprol; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Free Radical Scavengers; L-Lactate Dehydrogenase; Magnetic Resonance Spectroscopy; Male; PC12 Cells; Rats; Spinal Cord; Spinal Cord Injuries | 2017 |
Cannabinoid receptor 2 is increased in acutely and chronically inflamed bladder of rats.
Topics: Acrolein; Animals; Cystitis; Disease Models, Animal; Female; Ganglia, Spinal; Gene Expression Regulation; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; RNA, Messenger; Spinal Cord; Time Factors; Urinary Bladder | 2008 |
Intense correlation between brain infarction and protein-conjugated acrolein.
Topics: Acetylcysteine; Acrolein; Animals; Brain; Carrier Proteins; Disease Models, Animal; Down-Regulation; Free Radical Scavengers; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Photochemistry; Rose Bengal; Spermidine; Spermine; Time Factors; Up-Regulation | 2009 |
TRPA1 agonists evoke coughing in guinea pig and human volunteers.
Topics: Acrolein; Adult; Animals; Calcium Channels; Cough; Disease Models, Animal; Guinea Pigs; Humans; Male; Middle Aged; Nerve Tissue Proteins; Transient Receptor Potential Channels; TRPA1 Cation Channel; Vagus Nerve | 2009 |
Therapeutic effects on murine oral candidiasis by oral administration of cassia (Cinnamomum cassia) preparation.
Topics: Acrolein; Administration, Oral; Animals; Candida albicans; Candidiasis, Oral; Cinnamomum aromaticum; Cymbopogon; Disease Models, Animal; Drug Resistance, Fungal; Female; Mice; Mice, Inbred ICR; Phytotherapy; Plant Preparations | 2010 |
The role of T cells in the regulation of acrolein-induced pulmonary inflammation and epithelial-cell pathology.
Topics: Acrolein; Air Pollutants; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Interferon-gamma; Lung; Macrophages, Alveolar; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oligonucleotide Array Sequence Analysis; Pneumonia; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta; Respiratory Mucosa; T-Lymphocyte Subsets; Urban Health | 2009 |
Effects of nitric oxide on the primary bladder afferent activities of the rat with and without intravesical acrolein treatment.
Topics: Acrolein; Administration, Intravesical; Afferent Pathways; Animals; Arginine; Cystitis; Disease Models, Animal; Enzyme Inhibitors; Female; Irritants; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neural Conduction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Urinary Bladder | 2011 |
Brain infarction correlates more closely with acrolein than with reactive oxygen species.
Topics: Acrolein; Animals; Brain Infarction; Cell Line, Tumor; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Phospholipids; Reactive Oxygen Species; RNA; Spermine | 2011 |
Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1.
Topics: Acrolein; Activin Receptors, Type I; Acute Lung Injury; Animals; Disease Models, Animal; Female; Haplotypes; Mice; Mice, Inbred A; Polymorphism, Single Nucleotide; Protein Array Analysis | 2011 |
Further antinociceptive effects of myricitrin in chemical models of overt nociception in mice.
Topics: Acrolein; Amiloride; Analgesics, Non-Narcotic; Animals; Bradykinin; Camphor; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Flavonoids; Functional Laterality; Hyperalgesia; Male; Mice; Models, Chemical; Pain; Pain Measurement; Pain Threshold; Ruthenium Red | 2011 |
Use of polyamine metabolites as markers for stroke and renal failure.
Topics: Acrolein; Aged; Animals; Biomarkers; C-Reactive Protein; Cell Line, Tumor; Cell Proliferation; Diagnostic Imaging; Disease Models, Animal; Enzyme Assays; Female; Humans; Hydrogen Peroxide; Interleukin-6; Light; Male; Mice; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Renal Insufficiency; Spermine; Stroke; Thrombosis | 2011 |
Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels.
Topics: Acrolein; Analgesics; Animals; Calcium; Calcium Channels; Cells, Cultured; Disease Models, Animal; Freund's Adjuvant; Ganglia, Spinal; Gene Expression Regulation; Hemiterpenes; Humans; Inflammation; Membrane Potentials; Mice; Mice, Inbred ICR; Mice, Knockout; Nerve Tissue Proteins; Organophosphorus Compounds; Pain; Patch-Clamp Techniques; RNA, Messenger; RNA, Small Interfering; Sensory Receptor Cells; Transfection; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels | 2011 |
TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury.
Topics: Acetanilides; Acrolein; Animals; Ankyrins; Calcium Channels; Capsaicin; Carbachol; Disease Models, Animal; Ganglia, Spinal; Muscle Contraction; Oligonucleotides, Antisense; Purines; Rats; RNA, Messenger; Spinal Cord; Spinal Cord Injuries; TRPA1 Cation Channel; TRPC Cation Channels; Urinary Bladder; Urinary Bladder, Overactive; Urodynamics | 2011 |
Therapeutic effects of cinnamaldehyde and potentiation of its efficacy in combination with methylcellulose on murine oral candidiasis.
Topics: Acrolein; Administration, Oral; Animals; Candidiasis, Oral; Cassia; Disease Models, Animal; Drug Synergism; Female; Methylcellulose; Mice; Mice, Inbred ICR; Plant Preparations | 2011 |
Mass spectrometry-based quantification of myocardial protein adducts with acrolein in an in vivo model of oxidative stress.
Topics: Acrolein; Amino Acid Sequence; Animals; Chloroform; Chromatography, High Pressure Liquid; Disease Models, Animal; Malate Dehydrogenase; Male; Mitochondria, Heart; Mitochondrial ADP, ATP Translocases; Mitochondrial Proteins; Molecular Sequence Data; Myocardium; Oxidative Stress; Peptides; Proteome; Rats; Rats, Inbred F344; Tandem Mass Spectrometry | 2011 |
2-methoxycinnamaldehyde from Cinnamomum cassia reduces rat myocardial ischemia and reperfusion injury in vivo due to HO-1 induction.
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotonic Agents; Cinnamomum aromaticum; Coculture Techniques; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemodynamics; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Neutrophil Infiltration; NF-kappa B; Oxidative Stress; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; RNA Interference; Superoxide Dismutase; Time Factors; Transfection; Troponin I; Tumor Necrosis Factor-alpha; U937 Cells; Vascular Cell Adhesion Molecule-1; Ventricular Function, Left; Ventricular Pressure | 2012 |
Regular ingestion of cinnamomi cortex pulveratus offers gastroprotective activity in mice.
Topics: Acrolein; Animals; Anti-Ulcer Agents; Aspirin; Cinnamomum zeylanicum; Disease Models, Animal; Drugs, Chinese Herbal; Ethanol; Indomethacin; Male; Mice; Stomach Ulcer | 2013 |
GC-MS analysis and screening of antidiabetic, antioxidant and hypolipidemic potential of Cinnamomum tamala oil in streptozotocin induced diabetes mellitus in rats.
Topics: Acrolein; Administration, Oral; Animals; Antioxidants; Biomarkers; Blood Glucose; Cinnamomum; Diabetes Mellitus, Experimental; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glutathione; Glycated Hemoglobin; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Lipids; Liver; Male; Malondialdehyde; Oils, Volatile; Plant Leaves; Plant Oils; Rats; Rats, Wistar; Time Factors | 2012 |
[Effect of acrolein exposure on the percentage of CD4⁺CD25⁺ regulatory T cells and expression of transcription factor Foxp3 in asthmatic rats].
Topics: Acrolein; Animals; Asthma; Disease Models, Animal; Forkhead Transcription Factors; Male; Rats; Rats, Wistar; T-Lymphocytes, Regulatory | 2012 |
2-Hydroxycinnamaldehyde inhibits the epithelial-mesenchymal transition in breast cancer cells.
Topics: Acrolein; Animals; Antineoplastic Agents; Benzoates; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Movement; Cell Survival; Cinnamates; Disease Models, Animal; Epidermal Growth Factor; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Differentiation Protein 1; MCF-7 Cells; Mice; Neoplasm Metastasis; Snail Family Transcription Factors; Transcription Factors; Transcriptional Activation; Wnt Signaling Pathway | 2013 |
Effect of 2'-benzoyl-oxycinnamaldehyde on RPE cells in vitro and in an experimental proliferative vitreoretinopathy model.
Topics: Acrolein; Adolescent; Adult; Animals; Apoptosis; Arabidopsis Proteins; CDC2-CDC28 Kinases; Cell Division; Cells, Cultured; Cyclin D; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Disease Models, Animal; Down-Regulation; GADD45 Proteins; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Middle Aged; Phosphorylation; Pigment Epithelium of Eye; Plant Proteins; Potassium Channels; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins c-bcl-2; Rabbits; Retina; Tumor Suppressor Protein p53; Vitreoretinopathy, Proliferative | 2002 |
Ischemic insult exacerbates acrolein-induced conduction loss and axonal membrane disruption in guinea pig spinal cord white matter.
Topics: Acrolein; Action Potentials; Animals; Axons; Cell Membrane; Disease Models, Animal; Female; Free Radicals; Glucose; Guinea Pigs; Hypoxia; Lipid Peroxidation; Neural Conduction; Oxidative Stress; Reperfusion Injury; Spinal Cord Ischemia | 2003 |
Oxidative damage is a potential cause of cone cell death in retinitis pigmentosa.
Topics: Acrolein; Aldehydes; Animals; Animals, Genetically Modified; Biomarkers; Cell Communication; Cell Death; Cell Survival; Disease Models, Animal; DNA Damage; Hyperoxia; Immunohistochemistry; Lipid Peroxidation; Nerve Degeneration; Oxidative Stress; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Retinitis Pigmentosa; Sus scrofa | 2005 |
Effects of alpha tocopherol and probucol supplements on allergen-induced airway inflammation and hyperresponsiveness in a mouse model of allergic asthma.
Topics: Acrolein; Allergens; alpha-Tocopherol; Animals; Antioxidants; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Dietary Supplements; Dinoprost; Disease Models, Animal; Eosinophils; Female; Hypersensitivity; Immunoglobulin E; Interleukin-4; Interleukin-5; Mice; Mice, Inbred BALB C; Ovalbumin; Oxidative Stress; Probucol | 2006 |
Aldehyde load in ischemia-reperfusion brain injury: neuroprotection by neutralization of reactive aldehydes with phenelzine.
Topics: Acrolein; Aldehydes; Animals; Brain; Brain Ischemia; Cells, Cultured; Disease Models, Animal; Gerbillinae; Male; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Phenelzine; Propylamines; Rats; Reperfusion Injury; Retina; Retinal Ganglion Cells; Time Factors | 2006 |
A model of hemorrhagic cystitis induced with acrolein in mice.
Topics: Acrolein; Animals; Cystitis; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Hemorrhage; Male; Mesna; Mice; Protective Agents; Urinary Bladder | 2006 |
Induction of COX-2 expression by acrolein in the rat model of hemorrhagic cystitis.
Topics: Acrolein; Administration, Intravesical; Animals; Cyclooxygenase 2; Cystitis; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Induction; Hemorrhage; Male; Organ Size; Rats; Rats, Wistar; Time Factors; Urinary Bladder | 2008 |
The effects of acetaldehyde and acrolein on blood pressure in guanethidine-pretreated hypertensive rats.
Topics: Acetaldehyde; Acrolein; Aldehydes; Animals; Blood Pressure; Disease Models, Animal; Drug Interactions; Ethanol; Guanethidine; Hypertension; Nicotiana; Plants, Toxic; Rats; Rats, Inbred Strains; Smoke | 1983 |
Ifosfamide metabolite chloroacetaldehyde causes Fanconi syndrome in the perfused rat kidney.
Topics: Absorption; Acetaldehyde; Acrolein; Animals; Chemotherapy, Cancer, Regional Perfusion; Disease Models, Animal; Fanconi Syndrome; Glucose; Ifosfamide; Kidney; Kidney Tubules, Proximal; Male; Organ Size; Phosphates; Prodrugs; Rats; Rats, Inbred Lew; Sodium; Sulfates | 1994 |
An interlaboratory evaluation of the Buehler test for the identification and classification of skin sensitizers.
Topics: 1-Propanol; Acrolein; Allergens; Animals; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Disease Models, Animal; Ethanol; Eugenol; Europe; European Union; Evaluation Studies as Topic; Guidelines as Topic; Guinea Pigs; Irritants; Laboratories; Legislation, Medical; Patch Tests; Propanols; Reproducibility of Results; Risk Assessment; Risk Management; Sensitivity and Specificity | 1996 |
Cyclophosphamide-induced cystitis in freely-moving conscious rats: behavioral approach to a new model of visceral pain.
Topics: Acrolein; Animals; Antineoplastic Agents, Alkylating; Behavior, Animal; Consciousness; Cyclophosphamide; Cystitis; Disease Models, Animal; Female; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Pelvic Pain; Rats; Rats, Sprague-Dawley; Urinary Bladder | 2000 |
Failure of acrolein to produce sensitization in the guinea pig maximization test.
Topics: Acrolein; Aldehydes; Animals; Dermatitis, Contact; Disease Models, Animal; Female; Guinea Pigs | 1990 |
Evaluation of N-acetylcysteine and methylprednisolone as therapies for oxygen and acrolein-induced lung damage.
Topics: Acrolein; Administration, Inhalation; Aldehydes; Animals; Cystine; Disease Models, Animal; Injections, Intravenous; Lung Diseases; Methylprednisolone; Organ Size; Oxygen; Rats; Rats, Inbred Strains | 1990 |
[Problem of correlating the effect of carbon fiber dust on the body and the degree of migration of residual monomers and the products of their thermal destruction in a model biological media].
Topics: Acrolein; Acrylonitrile; Air Pollutants, Occupational; Aldehydes; Animals; Chemical Industry; Disease Models, Animal; Hot Temperature; Humans; Hydrogen Cyanide; Nitriles; Occupational Diseases; Pulmonary Fibrosis; Rats; Rats, Inbred Strains | 1989 |