acrolein has been researched along with Cystitis in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (21.21) | 18.7374 |
| 1990's | 5 (15.15) | 18.2507 |
| 2000's | 14 (42.42) | 29.6817 |
| 2010's | 6 (18.18) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Albo, M; Chiang, G; Khimji, C; Lee, J; Lee, S; Malkmus, S; Yaksh, T | 1 |
| Bjorling, DE; Wang, P; Wang, ZY | 1 |
| Chai, Y; Dai, M; Fan, Z; Huang, F; Huang, H; Jiang, Q; Li, X; Liu, Q; Lu, Y; Mai, Q; Meng, F; Shen, K; Sun, J; Wei, Q; Xu, D; Xu, N; Yu, G; Zhang, Y; Zhao, H; Zhou, D; Zhou, H; Zhou, Y | 1 |
| Angara, B; Arditi, M; Bhowmick, NA; Dru, C; Duong, F; Fernandez, A; Haldar, S; Mishra, R; Tripathi, M | 1 |
| Fan, J; Gao, S; Huang, Y; Kamiyama, M; Koizumi, S; Mitsui, T; Takeda, M; Tanaka, M; Yao, J; Zhang, X; Zhang, Z | 1 |
| Bjorling, DE; Guerios, SD; Merriam, FV; Wang, ZY | 1 |
| Alfieri, AB; Linares-Fernández, B | 1 |
| Bhatnagar, A; Conklin, DJ; Haberzettl, P; Lesgards, JF; Prough, RA; Srivastava, S | 1 |
| Aizawa, N; Igawa, Y; Nishizawa, O; Wyndaele, JJ | 1 |
| Liu, SH; Wang, CC; Weng, TI; Wu, ET; Wu, MH; Yang, RS | 1 |
| Boucher, M; Coudoré-Civiale, MA; Eschalier, A; Méen, M; Parry, L | 1 |
| Avelino, A; Bevan, S; Charrua, A; Cruz, F; Dinis, P; Nagy, I; Yaqoob, M | 1 |
| Batista, CK; Brito, GA; Cunha, FQ; Leitão, BT; Mota, JM; Ribeiro, RA; Souza, MH; Souza, ML | 1 |
| Batista, CK; Brito, GA; Cunha, FQ; Leitão, BT; Ribeiro, RA; Souza, ML | 1 |
| Korkmaz, A; Oter, S; Topal, T | 1 |
| Bjorling, DE; Boldon, K; Bushman, W; Elkahwaji, JE; Hopkins, WJ; Janda, LM; Wang, ZY | 1 |
| Almeida, PR; Baltazar, F; Macedo, FY; Mota, JM; Mourão, LC; Ribeiro, RA; Schmitt, FC | 1 |
| Bjorling, DE; Boldon, K; Bushman, W; Guerios, SD; Wang, ZY | 1 |
| Saiers, JH; Slavik, M | 1 |
| Ahluwalia, A; Giuliani, S; Lecci, A; Maggi, CA; Santicioli, P | 1 |
| Hader, JE; Jacobs, SC; Marzella, L; Myers, RA; Naslund, MJ | 1 |
| de Groat, WC; Erdman, SL; Vizzard, MA | 1 |
| Al-Fiar, F; Al-Rawithi, S; El-Yazigi, A; Ernst, P; Nicholls, PJ | 1 |
| Belichard, P; Defrêne, E; Duclos, H; Faye, P; Franck, RM; Luccarini, JM; Paquet, JL; Pruneau, D | 1 |
| Boucher, M; Codron, JP; Coudore, F; Eschalier, A; Kemeny, JL; Meen, M | 1 |
| Cubeddu, LX; Malave, A; Xu, X | 1 |
| Malley, SE; Vizzard, MA | 1 |
| Brock, N; Niemeyer, U; Pohl, J; Scheffler, G; Stekar, J | 1 |
| Abel, G; Cox, PJ | 1 |
| Cox, PJ | 2 |
| Levine, LA; Richie, JP | 1 |
| Chaviano, AH; Gill, WB; Ruggiero, KJ; Vermeulen, CW | 1 |
2 review(s) available for acrolein and Cystitis
| Article | Year |
|---|---|
Pathophysiological aspects of cyclophosphamide and ifosfamide induced hemorrhagic cystitis; implication of reactive oxygen and nitrogen species as well as PARP activation.
Topics: Acrolein; Antineoplastic Agents; Cell Death; Cyclophosphamide; Cystitis; Cytokines; DNA Damage; Enzyme Activation; Hemorrhage; Humans; Ifosfamide; Lipid Peroxidation; Mesna; Nitrogen; Oxygen; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Transcription Factors | 2007 |
Urological complications of cyclophosphamide.
Topics: Acrolein; Adult; Carcinoma, Transitional Cell; Child; Cyclophosphamide; Cystitis; Dose-Response Relationship, Drug; Humans; Urinary Bladder Neoplasms; Urination Disorders | 1989 |
2 trial(s) available for acrolein and Cystitis
| Article | Year |
|---|---|
Continuous IV infusion of MESNA can prevent hemorrhagic cystitis in HSCT and retain MESNA concentration in urine.
Topics: Acrolein; Adolescent; Adult; Aged; Allografts; Biotransformation; Child; Cyclophosphamide; Cystitis; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Hemorrhage; Histocompatibility; Humans; Incidence; Infusions, Intravenous; Mesna; Middle Aged; Proportional Hazards Models; Prospective Studies; Retrospective Studies; Transplantation Conditioning; Young Adult | 2015 |
Urinary excretion and pharmacokinetics of acrolein and its parent drug cyclophosphamide in bone marrow transplant patients.
Topics: Acrolein; Adolescent; Adult; Bone Marrow Transplantation; Cyclophosphamide; Cystitis; Female; Graft Rejection; Humans; Immunosuppressive Agents; Male; Middle Aged; Transplantation, Homologous | 1998 |
29 other study(ies) available for acrolein and Cystitis
| Article | Year |
|---|---|
Repeated Low-Dose Acrolein Triggers Irreversible Lamina Propria Edema in Urinary Bladder, Transient Voiding Behavior and Widening of Eyes to Mechanical Stimuli.
Topics: Acrolein; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Cyclophosphamide; Cystitis; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Hemorrhage; Humans; Mice; Mucous Membrane; Muscle, Smooth; Urinary Bladder | 2021 |
Activation of cannabinoid receptor 2 inhibits experimental cystitis.
Topics: Acrolein; Animals; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cystitis; Dose-Response Relationship, Drug; Female; Hyperalgesia; Indenes; Indoles; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Pain Measurement; Pyrazoles; Receptor, Cannabinoid, CB2; Severity of Illness Index | 2013 |
Histone deacetylase inhibitors mediate DNA damage repair in ameliorating hemorrhagic cystitis.
Topics: Acrolein; Animals; Cells, Cultured; Cyclophosphamide; Cystitis; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Glycosylases; DNA Methyltransferase 3B; DNA Repair; Down-Regulation; Female; Histone Deacetylase Inhibitors; Hydroxamic Acids; Mesna; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Niacinamide; Reactive Oxygen Species; Urinary Bladder; Vorinostat | 2016 |
Carbenoxolone inhibits TRPV4 channel-initiated oxidative urothelial injury and ameliorates cyclophosphamide-induced bladder dysfunction.
Topics: Acrolein; Animals; Calcium; Carbenoxolone; Cyclophosphamide; Cystitis; Enzyme Activation; Female; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; TRPV Cation Channels; Urinary Bladder; Urothelium | 2017 |
Cannabinoid receptor 2 is increased in acutely and chronically inflamed bladder of rats.
Topics: Acrolein; Animals; Cystitis; Disease Models, Animal; Female; Ganglia, Spinal; Gene Expression Regulation; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; RNA, Messenger; Spinal Cord; Time Factors; Urinary Bladder | 2008 |
[Changes in nitric oxide, prostaglandins and myeloperoxidase activity in acrolein-induced cystitis in rats].
Topics: Acrolein; Androstanes; Animals; Benzimidazoles; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cystitis; Dinoprostone; Drug Evaluation, Preclinical; Lactones; Male; Meloxicam; Membrane Proteins; Neurokinin-1 Receptor Antagonists; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulfones; Thiazines; Thiazoles; Urinary Bladder | 2009 |
Increased sensitivity of glutathione S-transferase P-null mice to cyclophosphamide-induced urinary bladder toxicity.
Topics: Acetylcysteine; Acrolein; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Cystitis; Glutathione Transferase; Hemorrhage; Immunohistochemistry; In Situ Nick-End Labeling; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Size; Reverse Transcriptase Polymerase Chain Reaction; Urinary Bladder; Urinary Bladder Diseases | 2009 |
Effects of nitric oxide on the primary bladder afferent activities of the rat with and without intravesical acrolein treatment.
Topics: Acrolein; Administration, Intravesical; Afferent Pathways; Animals; Arginine; Cystitis; Disease Models, Animal; Enzyme Inhibitors; Female; Irritants; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neural Conduction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Urinary Bladder | 2011 |
Involvement of interleukin-6-regulated nitric oxide synthase in hemorrhagic cystitis and impaired bladder contractions in young rats induced by acrolein, a urinary metabolite of cyclophosphamide.
Topics: Acrolein; Animals; Blotting, Western; Cyclophosphamide; Cystitis; Female; Hemorrhage; Immunohistochemistry; Interleukin-6; Muscle Contraction; Muscle, Smooth; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Urinary Bladder | 2013 |
Involvement of N-methyl-D-aspartate receptors in nociception in the cyclophosphamide-induced vesical pain model in the conscious rat.
Topics: Acrolein; Animals; Antineoplastic Agents, Alkylating; Behavior, Animal; Cyclophosphamide; Cystitis; Dizocilpine Maleate; Dose-Response Relationship, Drug; Injections, Intravenous; Injections, Spinal; Ketamine; Male; Models, Animal; Pain; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2002 |
Anandamide-evoked activation of vanilloid receptor 1 contributes to the development of bladder hyperreflexia and nociceptive transmission to spinal dorsal horn neurons in cystitis.
Topics: Acrolein; Animals; Arachidonic Acids; Capsaicin; Cyclophosphamide; Cystitis; Endocannabinoids; Female; Hydrolysis; Ion Channels; Pain; Polyunsaturated Alkamides; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Reflex, Abnormal; TRPV Cation Channels; Urinary Bladder | 2004 |
Amifostine and glutathione prevent ifosfamide- and acrolein-induced hemorrhagic cystitis.
Topics: Acrolein; Amifostine; Animals; Antidotes; Antineoplastic Agents, Alkylating; Cystitis; Dose-Response Relationship, Drug; Edema; Glutathione; Hemorrhage; Ifosfamide; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Radiation-Protective Agents; Urinary Bladder | 2007 |
A model of hemorrhagic cystitis induced with acrolein in mice.
Topics: Acrolein; Animals; Cystitis; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Hemorrhage; Male; Mesna; Mice; Protective Agents; Urinary Bladder | 2006 |
Acute acrolein-induced cystitis in mice.
Topics: Acrolein; Acute Disease; Administration, Intravesical; Animals; Cystitis; Dose-Response Relationship, Drug; Female; Irritants; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Severity of Illness Index; Urothelium | 2007 |
Induction of COX-2 expression by acrolein in the rat model of hemorrhagic cystitis.
Topics: Acrolein; Administration, Intravesical; Animals; Cyclooxygenase 2; Cystitis; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Induction; Hemorrhage; Male; Organ Size; Rats; Rats, Wistar; Time Factors; Urinary Bladder | 2008 |
Blockade of NGF and trk receptors inhibits increased peripheral mechanical sensitivity accompanying cystitis in rats.
Topics: Acrolein; Animals; Carbazoles; Cystitis; Drug Administration Routes; Enzyme Inhibitors; Female; Gene Expression Regulation; Hyperalgesia; Indole Alkaloids; Nerve Growth Factor; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Wistar; Receptor, trkA; Receptors, Nerve Growth Factor; Time Factors; Urinary Bladder | 2008 |
Phase I clinical study of acetylcysteine's preventing ifosfamide-induced hematuria.
Topics: Acetylcysteine; Acrolein; Adenocarcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Cystitis; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Hematuria; Humans; Ifosfamide; Lung Neoplasms | 1983 |
Characterization of the capsaicin-sensitive component of cyclophosphamide-induced inflammation in the rat urinary bladder.
Topics: Acrolein; Animals; Blood Proteins; Bradykinin; Capsaicin; Cyclophosphamide; Cystitis; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Neurons, Afferent; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Urinary Bladder | 1994 |
Hyperbaric oxygen treatment for experimental cyclophosphamide-induced hemorrhagic cystitis.
Topics: Acrolein; Animals; Cyclophosphamide; Cystitis; Female; Hemorrhage; Hyperbaric Oxygenation; Rats; Rats, Sprague-Dawley; Urinary Bladder; Urinary Bladder Diseases | 1993 |
Increased expression of neuronal nitric oxide synthase in bladder afferent pathways following chronic bladder irritation.
Topics: Acrolein; Afferent Pathways; Animals; Antineoplastic Agents; Cyclophosphamide; Cystitis; Female; Ganglia, Spinal; Immunohistochemistry; Irritants; Male; Neurons; Nitric Oxide Synthase; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spinal Cord; Urinary Bladder | 1996 |
Pharmacological and molecular evidence for kinin B1 receptor expression in urinary bladder of cyclophosphamide-treated rats.
Topics: Acrolein; Animals; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Cyclophosphamide; Cystitis; Dose-Response Relationship, Drug; Gene Expression Regulation; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Protease Inhibitors; Rats; Rats, Wistar; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin; RNA, Messenger; Urinary Bladder; Urothelium | 1999 |
Cyclophosphamide-induced cystitis in freely-moving conscious rats: behavioral approach to a new model of visceral pain.
Topics: Acrolein; Animals; Antineoplastic Agents, Alkylating; Behavior, Animal; Consciousness; Cyclophosphamide; Cystitis; Disease Models, Animal; Female; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Pelvic Pain; Rats; Rats, Sprague-Dawley; Urinary Bladder | 2000 |
Expression of inducible nitric oxide synthase in primary culture of rat bladder smooth muscle cells by plasma from cyclophosphamide-treated rats.
Topics: Acrolein; Animals; Cells, Cultured; Cyclophosphamide; Cystitis; Dose-Response Relationship, Drug; Hemorrhage; Interferon-gamma; Isothiuronium; Male; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organ Size; Plasma; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Urinary Bladder | 2001 |
Changes in urinary bladder cytokine mRNA and protein after cyclophosphamide-induced cystitis.
Topics: Acrolein; Animals; Cyclophosphamide; Cystitis; Cytokines; Drug Administration Schedule; Female; Injections, Intraperitoneal; Organ Size; Proteins; Rats; Rats, Wistar; RNA, Messenger; Up-Regulation; Urinary Bladder | 2002 |
Acrolein, the causative factor of urotoxic side-effects of cyclophosphamide, ifosfamide, trofosfamide and sufosfamide.
Topics: Acrolein; Aldehydes; Animals; Cyclophosphamide; Cystitis; Female; Ifosfamide; Inactivation, Metabolic; Kidney; Male; Mesna; Rats; Urinary Bladder; Urinary Tract; Urologic Diseases | 1979 |
Cyclophosphamide cystitis. Studies aimed at its minimization.
Topics: Acrolein; Animals; Carcinoma 256, Walker; Croton Oil; Cyclophosphamide; Cystitis; Kinetics; Male; Organ Size; Rats; Succimer; Time Factors; Urinary Bladder | 1979 |
Cyclophosphamide cystitis--identification of acrolein as the causative agent.
Topics: Acetylcysteine; Acrolein; Aldehydes; Animals; Carcinoma 256, Walker; Cyclophosphamide; Cystitis; Female; Male; Organ Size; Rats; Urinary Bladder | 1979 |
Cyclophosphamide cystitis and bladder cancer. A hypothesis.
Topics: Acrolein; Cyclophosphamide; Cystitis; Humans; Urinary Bladder; Urinary Bladder Neoplasms | 1979 |
Experimental cytoxan cystitis and prevention by acetylcysteine.
Topics: Acetylcysteine; Acrolein; Animals; Cyclophosphamide; Cystitis; Female; Rats; Urinary Bladder | 1985 |