Page last updated: 2024-08-18

acrolein and Allodynia

acrolein has been researched along with Allodynia in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (17.65)29.6817
2010's14 (82.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Acosta, G; Butler, B; Shi, R1
Hurley, JH; Johnson, PL; Kunkler, PE; Oxford, GS; Zhang, L1
Lötsch, J; Weyer-Menkhoff, I1
Chae, HK; Kim, SK; Kim, W1
Bjorling, DE; Wang, P; Wang, ZY1
Córdova, MM; Montrucchio, DP; Santos, AR1
Falck, L; Koivisto, A; Lasierra, M; Pertovaara, A; Saarnilehto, M; Viisanen, H; Wei, H1
Baggio, CH; Cipriani, TR; da Silva, CF; de Souza, LM; Hamm, LA; Nascimento, AM; Nomura, EC; Rodrigues, MR; Werner, MF1
Athayde, ML; Boligon, AA; Ferreira, J; Hoffmeister, C; Klafke, JZ; Pinheiro, FV; Pinheiro, KV; Rosa, F; Rossato, MF; Tonello, R; Trevisan, G1
Acosta, G; Cao, P; Chen, Z; Muratori, B; Park, J; Shi, R; Vega-Alvarez, S; Zheng, L1
Andersen, HH; Arendt-Nielsen, L; Gazerani, P1
Chai, Z; Feng, X; Hu, M; Huang, R; Liu, B; Liu, T; Shang, S; Sun, L; Teng, S; Wang, C; Wang, L; Wang, Y; Wu, Q; Wu, X; Xu, H; Zhang, C; Zhang, F; Zhang, X; Zheng, L; Zhou, Z; Zhu, D; Zhu, F; Zhu, MX1
Abzianidze, E; Carstens, E; Carstens, MI; Gurtskaia, G; Klein, AH; Sawyer, CM; Tsagareli, MG; Tsiklauri, N; Zanotto, KL1
Córdova, MM; Pizzolatti, MG; Ruani, AP; Santos, AR; Silva, MD; Werner, MF1
Handwerker, HO; Maihöfner, C; Namer, B; Seifert, F1
Carstens, E; Carstens, MI; Cuellar, JM; Judd, JH; Merrill, AW1
Bjorling, DE; Boldon, K; Bushman, W; Guerios, SD; Wang, ZY1

Trials

2 trial(s) available for acrolein and Allodynia

ArticleYear
TRPA1 Sensitization Produces Hyperalgesia to Heat but not to Cold Stimuli in Human Volunteers.
    The Clinical journal of pain, 2019, Volume: 35, Issue:4

    Topics: Acrolein; Adult; Capsaicin; Cold Temperature; Cross-Over Studies; Female; Healthy Volunteers; Hot Temperature; Humans; Hyperalgesia; Male; Menthol; Neuralgia; Pain Threshold; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels; Young Adult

2019
TRPA1 and TRPM8 activation in humans: effects of cinnamaldehyde and menthol.
    Neuroreport, 2005, Jun-21, Volume: 16, Issue:9

    Topics: Acrolein; Adult; Axons; Cross-Over Studies; Double-Blind Method; Female; Humans; Hyperalgesia; Ion Channels; Laser-Doppler Flowmetry; Male; Menthol; Neoplasm Proteins; Pain; Pain Measurement; Pain Threshold; Reflex; Time Factors; TRPM Cation Channels; Vasodilation

2005

Other Studies

15 other study(ies) available for acrolein and Allodynia

ArticleYear
Exogenous Acrolein intensifies sensory hypersensitivity after spinal cord injury in rat.
    Journal of the neurological sciences, 2017, Aug-15, Volume: 379

    Topics: Acrolein; Administration, Inhalation; Animals; Hyperalgesia; Male; Neuralgia; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tobacco Smoke Pollution

2017
Induction of chronic migraine phenotypes in a rat model after environmental irritant exposure.
    Pain, 2018, Volume: 159, Issue:3

    Topics: Acrolein; Analysis of Variance; Animals; Chronic Disease; Disease Models, Animal; Exploratory Behavior; Hyperalgesia; Irritants; Laser-Doppler Flowmetry; Male; Migraine Disorders; Physical Stimulation; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Smell; Sumatriptan; Trigeminal Nuclei; Vasoconstrictor Agents

2018
Phytochemicals of Cinnamomi Cortex: Cinnamic Acid, but not Cinnamaldehyde, Attenuates Oxaliplatin-Induced Cold and Mechanical Hypersensitivity in Rats.
    Nutrients, 2019, Feb-19, Volume: 11, Issue:2

    Topics: Acrolein; Analgesics; Animals; Antineoplastic Agents; Cinnamates; Cinnamomum aromaticum; Cinnamomum zeylanicum; Cold Temperature; Drugs, Chinese Herbal; Hyperalgesia; Male; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Rats, Sprague-Dawley; Spinal Cord

2019
Activation of cannabinoid receptor 2 inhibits experimental cystitis.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2013, May-15, Volume: 304, Issue:10

    Topics: Acrolein; Animals; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cystitis; Dose-Response Relationship, Drug; Female; Hyperalgesia; Indenes; Indoles; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Pain Measurement; Pyrazoles; Receptor, Cannabinoid, CB2; Severity of Illness Index

2013
Plant derived aporphinic alkaloid S-(+)-dicentrine induces antinociceptive effect in both acute and chronic inflammatory pain models: evidence for a role of TRPA1 channels.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Acetone; Acrolein; Acrylamides; Acute Disease; Alkaloids; Analgesics; Animals; Aporphines; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Chronic Pain; Cold Temperature; Freund's Adjuvant; Gene Expression; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Pain Measurement; Transient Receptor Potential Channels; TRPA1 Cation Channel

2013
Spinal transient receptor potential ankyrin 1 channel induces mechanical hypersensitivity, increases cutaneous blood flow, and mediates the pronociceptive action of dynorphin A.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2013, Volume: 64, Issue:3

    Topics: Acrolein; Analgesics, Non-Narcotic; Animals; Back Pain; Behavior, Animal; Cholecystokinin; Dinoprost; Dose-Response Relationship, Drug; Dynorphins; Hyperalgesia; Injections, Spinal; Male; Minocycline; Nerve Tissue Proteins; Oximes; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Wistar; Regional Blood Flow; Skin; TRPA1 Cation Channel; TRPC Cation Channels

2013
Antinociceptive effects of ethanolic extract from the flowers of Acmella oleracea (L.) R.K. Jansen in mice.
    Journal of ethnopharmacology, 2013, Nov-25, Volume: 150, Issue:2

    Topics: Acrolein; Analgesics; Animals; Asteraceae; Capsaicin; Ethanol; Flowers; Formaldehyde; Hot Temperature; Hyperalgesia; Ligation; Male; Mice; Pain; Phytotherapy; Plant Extracts; Sciatic Nerve; Solvents; Touch

2013
Gallic acid functions as a TRPA1 antagonist with relevant antinociceptive and antiedematogenic effects in mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 2014, Volume: 387, Issue:7

    Topics: Acrolein; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Edema; Gallic Acid; Hydrogen Peroxide; Hyperalgesia; Male; Mice; Pain; Psychomotor Performance; Sciatic Nerve; Spinal Cord; Transient Receptor Potential Channels; TRPA1 Cation Channel

2014
Acrolein contributes to TRPA1 up-regulation in peripheral and central sensory hypersensitivity following spinal cord injury.
    Journal of neurochemistry, 2015, Volume: 135, Issue:5

    Topics: Acetylcysteine; Acrolein; Animals; Disease Models, Animal; Ganglia, Spinal; Hydralazine; Hyperalgesia; Locomotion; Male; Neuralgia; Pain Threshold; Rats; Rats, Sprague-Dawley; Skin; Spinal Cord; Spinal Cord Injuries; TRPA1 Cation Channel; TRPC Cation Channels; Up-Regulation; Vasodilator Agents

2015
High-Concentration L-Menthol Exhibits Counter-Irritancy to Neurogenic Inflammation, Thermal and Mechanical Hyperalgesia Caused by Trans-cinnamaldehyde.
    The journal of pain, 2016, Volume: 17, Issue:8

    Topics: Acrolein; Adult; Antineoplastic Agents, Phytogenic; Antipruritics; Dose-Response Relationship, Drug; Female; Healthy Volunteers; Humans; Hyperalgesia; Male; Methionine; Neurogenic Inflammation; Pain Measurement; Pain Threshold; Physical Stimulation; Temperature; Visual Analog Scale; Young Adult

2016
Intracellular TRPA1 mediates Ca2+ release from lysosomes in dorsal root ganglion neurons.
    The Journal of cell biology, 2016, Nov-07, Volume: 215, Issue:3

    Topics: Acrolein; Animals; Calcitonin Gene-Related Peptide; Calcium; Calcium Signaling; Endoplasmic Reticulum; Endosomes; Exocytosis; Ganglia, Spinal; Hyperalgesia; Intracellular Space; Ion Channel Gating; Isothiocyanates; Lysosomes; Male; Mice, Inbred C57BL; Neurons; Neuropeptides; Solutions; Transient Receptor Potential Channels; TRPA1 Cation Channel

2016
Behavioral evidence of thermal hyperalgesia and mechanical allodynia induced by intradermal cinnamaldehyde in rats.
    Neuroscience letters, 2010, Apr-12, Volume: 473, Issue:3

    Topics: Acrolein; Animals; Ankyrins; Behavior, Animal; Calcium Channel Agonists; Calcium Channels; Cold Temperature; Hot Temperature; Hyperalgesia; Injections, Intradermal; Male; Pain; Rats; Rats, Sprague-Dawley; Touch; TRPA1 Cation Channel; TRPC Cation Channels

2010
Further antinociceptive effects of myricitrin in chemical models of overt nociception in mice.
    Neuroscience letters, 2011, May-20, Volume: 495, Issue:3

    Topics: Acrolein; Amiloride; Analgesics, Non-Narcotic; Animals; Bradykinin; Camphor; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Flavonoids; Functional Laterality; Hyperalgesia; Male; Mice; Models, Chemical; Pain; Pain Measurement; Pain Threshold; Ruthenium Red

2011
Effects of TRPA1 agonists mustard oil and cinnamaldehyde on lumbar spinal wide-dynamic range neuronal responses to innocuous and noxious cutaneous stimuli in rats.
    Journal of neurophysiology, 2008, Volume: 99, Issue:2

    Topics: Acrolein; Action Potentials; Analysis of Variance; Animals; Ankyrins; Calcium Channels; Drug Administration Routes; Hyperalgesia; Lumbosacral Region; Male; Mustard Plant; Neurons; Pain Threshold; Physical Stimulation; Plant Oils; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Temperature; TRPA1 Cation Channel; TRPC Cation Channels

2008
Blockade of NGF and trk receptors inhibits increased peripheral mechanical sensitivity accompanying cystitis in rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:1

    Topics: Acrolein; Animals; Carbazoles; Cystitis; Drug Administration Routes; Enzyme Inhibitors; Female; Gene Expression Regulation; Hyperalgesia; Indole Alkaloids; Nerve Growth Factor; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Wistar; Receptor, trkA; Receptors, Nerve Growth Factor; Time Factors; Urinary Bladder

2008