acrolein has been researched along with Acute Confusional Senile Dementia in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (4.55) | 18.2507 |
| 2000's | 13 (29.55) | 29.6817 |
| 2010's | 17 (38.64) | 24.3611 |
| 2020's | 12 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, C; Han, Y; Hou, J; Hu, Y; Liu, Q; Lu, J; Mak, MS; Peng, W; Pi, R; Tsim, KWK; Wang, S; Xin, W; Yang, Y; Zhou, X; Zhu, Z | 1 |
| Chen, C; Chen, X; Lu, J; Peng, W; Pi, J; Pi, R; Wang, S; Xin, W; Yang, X; Yang, Y; Yao, L; Yin, W; Zhou, X; Zhu, Z | 1 |
| Igarashi, K; Kashiwagi, K; Mizoi, M; Sakamoto, A; Terui, Y; Uemura, T; Waragai, M; Yoshida, M | 1 |
| Beauclair, T; Crodian, J; Dieterly, AM; Kim, D; Krishnan, N; Martinez, J; Mufti, SJ; Rogers, EA; Shi, R; Stingel, RL; Sun, S | 1 |
| Chang, TC; Hsu, CH; Hsu, IU; Huang, WC; Kao, SH; Lee, CK; Lin, YF; Sanotra, MR; Tu, FY | 1 |
| Jiang, X; Peng, W; Pi, R; Wang, S; Yang, S; Zhou, S | 1 |
| Mustafa, HN | 1 |
| Do, J; Gee, MS; Jeon, SH; Ju, YJ; Kim, JH; Kim, N; Lee, JK; Oh, MS | 1 |
| Fujii, M; Michiba, H; Muguruma, K; Ode, Y; Pradipta, AR; Tanaka, K; Terashima, K | 1 |
| Abdullah, BM; Amin, M; Shalamanova, L; Tang, S; Taylor, RL; Whitehead, KA; Wylie, S | 1 |
| Chen, C; Chen, Y; Chen, Z; Lu, J; Pi, R; Wang, C | 1 |
| Pradipta, AR; Tanaka, K | 2 |
| Chen, SP; Fuh, JL; Hsu, WC; Liu, TY; Tsou, HH; Wang, HT | 1 |
| Jafari, M; Pham, HM; Schriner, SE; Sevrioukov, EA; Xu, A | 1 |
| Chen, Y; Deng, H; Dong, X; Li, K; Wang, L; Wang, X; Wu, Y; Xu, Y; Zhao, Y | 1 |
| George, RC; Graves, DJ; Lew, J | 1 |
| Ihara, M; Kimura, H; Matsumura, K; Okamoto, Y; Ono, M; Saji, H; Takahashi, R; Watanabe, H; Yoshimura, M | 1 |
| Akatsu, H; Igarashi, K; Kashiwagi, K; Mizoi, M; Saiki, R; Uemura, K; Waragai, M; Yoshida, M | 1 |
| Higashi, K; Igarashi, K; Kashiwagi, K; Kuni, K; Mizoi, M; Nakamura, M; Saiki, R; Toida, T; Uemura, K; Waragai, M; Yoshida, M | 1 |
| Bernardi, C; Cecconi, F; Cerù, MP; Cimini, A; Fanelli, F; Fracassi, A; Moreno, S; Porcellotti, S; Sepe, S | 1 |
| Ameenuddin, S; Citron, BA; Festoff, BW; SantaCruz, K; Suo, WZ; Uchida, K | 1 |
| Bradley, MA; Lovell, MA; Markesbery, WR | 1 |
| Arseneault, M; Dang, TN; Murthy, V; Ramassamy, C | 1 |
| Arseneault, M; Dang, TN; Ramassamy, C; Singh, M | 1 |
| Arseneault, M; Dang, TN; Ramassamy, C; Waeg, G; Zarkovic, N | 1 |
| Arai, H; Hashimoto, M; Igarashi, K; Iwai, N; Kashiwagi, K; Mizoi, M; Saiki, R; Takagi, K; Tashiro, J; Uemura, K; Waragai, M; Yoshida, M | 1 |
| Abuladze, N; Bragin, A; Cascio, D; Damoiseaux, R; Faull, K; Pushkin, A; Schibler, MJ; Tsirulnikov, K | 1 |
| Chao, XJ; Chen, MH; Chen, XH; Dou, J; Huang, YJ; Jiang, YM; Jin, MH; Liu, PQ; Ouyang, Y; Pi, RB; Qin, J; Ramassamy, C; Yu, JC; Zhang, JJ | 1 |
| Aldini, G; Arlandini, E; Beretta, G; Carini, M; Facino, RM | 1 |
| Butterfield, DA; Pocernich, CB | 1 |
| Butterfield, DA; Castegna, A; Lauderback, CM; Mohmmad-Abdul, H | 1 |
| Seidler, NW; Yeargans, GS | 1 |
| Lovell, MA; Lynn, BC; Williams, TI | 1 |
| Lovell, MA; Lynn, BC; Markesbery, WR; Williams, TI | 1 |
| Seidler, NW; Squire, TJ | 1 |
| Kawaguchi-Niida, M; Kobayashi, M; Morikawa, S; Sawada, T; Shibata, N; Uchida, K; Yamamoto, T | 1 |
| Craig, HD; Seidler, NW; Squire, TJ | 1 |
| Montine, TJ; Picklo, MJ | 1 |
| Barber, DS; Gavin, T; LoPachin, RM | 1 |
| Burcham, PC; Kaminskas, LM; Pyke, SM; Tan, D | 1 |
| Calingasan, NY; Gibson, GE; Uchida, K | 1 |
| Uchida, K | 1 |
| Lovell, MA; Markesbery, WR; Xie, C | 1 |
10 review(s) available for acrolein and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Disease-associated acrolein: A possible diagnostic and therapeutic substrate for in vivo synthetic chemistry.
Topics: Acrolein; Alzheimer Disease; Autoimmune Diseases; Brain Diseases; Humans; Lysine; Polyamines; Proteins | 2020 |
Polyamine biomarkers as indicators of human disease.
Topics: Acrolein; Alzheimer Disease; Apoptosis; Biomarkers; Biotransformation; Cadaverine; Cell Movement; Humans; Leukocytes; Neoplasms; Periodontitis; Putrescine; Renal Insufficiency, Chronic; Spermidine; Spermine | 2021 |
Application of Acrolein Imines to Organic Synthesis, Biofunctional Studies, and Clinical Practice.
Topics: Acrolein; Alzheimer Disease; Breast Neoplasms; Female; Humans; Imines; Molecular Structure; Oxidative Stress | 2021 |
Unexplored Chemical Reactions of Endogenous Acrolein: Detection, Toxicity, and Biological Roles.
Topics: Acrolein; Alzheimer Disease; Amyloid beta-Peptides; Azides; Biogenic Amines; Biomarkers; Cycloaddition Reaction; Environmental Pollutants; Imines; Molecular Imaging; Neoplasms; Oxidative Stress; Peptide Fragments | 2017 |
Potential role of acrolein in neurodegeneration and in Alzheimer's disease.
Topics: Acrolein; Alzheimer Disease; Animals; Apoptosis; DNA Adducts; Glutathione Transferase; Humans; Lipid Peroxidation; Mice; Polyamines; Rats | 2010 |
Role of by-products of lipid oxidation in Alzheimer's disease brain: a focus on acrolein.
Topics: Acrolein; Alzheimer Disease; Brain; Humans; Lipid Peroxidation; Oxidative Stress | 2010 |
Mitochondrial effects of lipid-derived neurotoxins.
Topics: Acrolein; Alzheimer Disease; Brain; Humans; Lipid Peroxidation; Metabolic Detoxication, Phase I; Mitochondria; Neurotoxins; Oxidative Stress | 2007 |
Molecular mechanisms of the conjugated alpha,beta-unsaturated carbonyl derivatives: relevance to neurotoxicity and neurodegenerative diseases.
Topics: Acrolein; Acrylamide; Aldehydes; Alzheimer Disease; Animals; Brain; Disease Models, Animal; DNA Adducts; DNA Damage; Humans; Neurotoxicity Syndromes | 2008 |
Carbonyl-scavenging drugs & protection against carbonyl stress-associated cell injury.
Topics: Acrolein; Alzheimer Disease; Animals; Atherosclerosis; Cell Death; Free Radical Scavengers; Humans; Hydralazine; Liver Diseases, Alcoholic; Oxidative Stress; Protective Agents; Spinal Cord Injuries | 2008 |
Current status of acrolein as a lipid peroxidation product.
Topics: Acrolein; Air Pollutants; Aldehydes; Alzheimer Disease; Arteriosclerosis; Cross-Linking Reagents; Fatty Acids, Unsaturated; Glyoxal; Humans; Lipid Peroxidation; Lipid Peroxides; Lysine; Malondialdehyde; Oxidative Stress | 1999 |
34 other study(ies) available for acrolein and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Acrolein, an endogenous aldehyde induces Alzheimer's disease-like pathologies in mice: A new sporadic AD animal model.
Topics: Acrolein; Actin Depolymerizing Factors; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Hippocampus; Male; Mice, Inbred C57BL; Neurons; Olfactory Bulb; Peptide Fragments; Phosphorylation; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Synapsins; tau Proteins | 2022 |
Acrolein, an endogenous aldehyde induces synaptic dysfunction in vitro and in vivo: Involvement of RhoA/ROCK2 pathway.
Topics: Acrolein; Aldehydes; Alzheimer Disease; Animals; Disease Models, Animal; Hippocampus; Humans; Mice; rho-Associated Kinases; rhoA GTP-Binding Protein | 2022 |
Urinary Amino Acid-Conjugated Acrolein and Taurine as New Biomarkers for Detection of Dementia.
Topics: Acrolein; Alzheimer Disease; Biomarkers; Cognitive Dysfunction; Humans; Lysine; Quality of Life | 2023 |
The contribution of initial concussive forces and resulting acrolein surge to β-amyloid accumulation and functional alterations in neuronal networks using a TBI-on-a-chip model.
Topics: Acrolein; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain Injuries, Traumatic; Inflammation; Lab-On-A-Chip Devices; Mice; Tumor Necrosis Factor-alpha | 2023 |
Acrolein adducts and responding autoantibodies correlate with metabolic disturbance in Alzheimer's disease.
Topics: Acrolein; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Autoantibodies; Biomarkers; Chromatography, Liquid; Humans; Immunoglobulin M; Mice; Tandem Mass Spectrometry | 2023 |
Acrolein Induces Retinal Abnormalities of Alzheimer's Disease in Mice.
Topics: Acrolein; Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Mice; Retina | 2023 |
Neuro-amelioration of cinnamaldehyde in aluminum-induced Alzheimer's disease rat model.
Topics: Acrolein; Aluminum; Aluminum Chloride; Aluminum Compounds; Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Hippocampus; Male; Memory; Neurofibrillary Tangles; Neuroprotective Agents; Oxidative Stress; Plaque, Amyloid; Rats, Wistar | 2020 |
Trans-Cinnamaldehyde Alleviates Amyloid-Beta Pathogenesis via the SIRT1-PGC1α-PPARγ Pathway in 5XFAD Transgenic Mice.
Topics: Acrolein; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antimutagenic Agents; Female; Gene Expression Regulation; Humans; Male; Mice; Mice, Transgenic; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Sirtuin 1 | 2020 |
Acrolein-conjugated proteomics in brains of adult C57BL/6 mice chronically exposed to acrolein and aged APP/PS1 transgenic AD mice.
Topics: Acrolein; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Proteomics | 2021 |
Alterations in Acrolein Metabolism Contribute to Alzheimer's Disease.
Topics: Acetylcysteine; Acrolein; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Case-Control Studies; Creatinine; Disease Progression; Early Diagnosis; Female; Humans; Male; Middle Aged | 2018 |
Cinnamaldehyde Improves Lifespan and Healthspan in
Topics: Acrolein; Alzheimer Disease; Animals; Disease Models, Animal; Drosophila melanogaster; Longevity; tau Proteins | 2018 |
Trans-cinnamaldehyde improves neuroinflammation-mediated NMDA receptor dysfunction and memory deficits through blocking NF-κB pathway in presenilin1/2 conditional double knockout mice.
Topics: Acrolein; Alzheimer Disease; Animals; Female; Hippocampus; I-kappa B Proteins; Long-Term Potentiation; Male; Memory Disorders; Mice; Mice, Knockout; Microglia; N-Methylaspartate; Neuroprotective Agents; NF-kappa B; Presenilin-1; Presenilin-2; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2019 |
Interaction of cinnamaldehyde and epicatechin with tau: implications of beneficial effects in modulating Alzheimer's disease pathogenesis.
Topics: Acrolein; Alzheimer Disease; Animals; Catechin; Cattle; Cysteine; In Vitro Techniques; Microscopy, Electron, Transmission; Microtubules; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization; tau Proteins; Tubulin | 2013 |
Synthesis and biological evaluation of novel styryl benzimidazole derivatives as probes for imaging of neurofibrillary tangles in Alzheimer's disease.
Topics: Acrolein; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Animals; Autoradiography; Benzimidazoles; Brain; Female; Humans; Iodine Radioisotopes; Iodobenzenes; Male; Mice; Neurofibrillary Tangles; Peptide Fragments; Positron-Emission Tomography; Radiopharmaceuticals; tau Proteins; Tissue Distribution | 2013 |
Distinction between mild cognitive impairment and Alzheimer's disease by CSF amyloid β40 and β42, and protein-conjugated acrolein.
Topics: Acrolein; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Cognitive Dysfunction; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Peptide Fragments | 2014 |
Distinguishing mild cognitive impairment from Alzheimer's disease with acrolein metabolites and creatinine in urine.
Topics: Acetylcysteine; Acrolein; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cognitive Dysfunction; Creatinine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged | 2015 |
Oxidative Stress during the Progression of β-Amyloid Pathology in the Neocortex of the Tg2576 Mouse Model of Alzheimer's Disease.
Topics: Acrolein; Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; ATP-Binding Cassette Transporters; Disease Models, Animal; Down-Regulation; Female; Genotype; Glial Fibrillary Acidic Protein; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Neocortex; Nerve Tissue Proteins; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Peroxisomes; PPAR alpha; Superoxide Dismutase; Superoxide Dismutase-1; Transcription Factors | 2015 |
Membrane lipid peroxidation in neurodegeneration: Role of thrombin and proteinase-activated receptor-1.
Topics: Acrolein; Aldehydes; Alzheimer Disease; Animals; Cells, Cultured; Cytoplasm; Dose-Response Relationship, Drug; Humans; Lipid Peroxidation; Membrane Lipids; Mice; Motor Neurons; Parkinson Disease; Receptor, PAR-1; Thrombin | 2016 |
Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease.
Topics: Acrolein; Aged, 80 and over; Aldehydes; Alzheimer Disease; Brain; Brain Chemistry; Female; Gas Chromatography-Mass Spectrometry; Humans; Immunoblotting; Immunohistochemistry; Male | 2010 |
Molecular regulations induced by acrolein in neuroblastoma SK-N-SH cells: relevance to Alzheimer's disease.
Topics: Acrolein; Alzheimer Disease; Cell Line, Tumor; DNA Adducts; DNA Fragmentation; Free Radicals; Humans; Lipid Peroxidation; Neuroblastoma; Oxidative Stress | 2010 |
Increased protein-conjugated acrolein and amyloid-β40/42 ratio in plasma of patients with mild cognitive impairment and Alzheimer's disease.
Topics: Acrolein; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Atrophy; Biomarkers; Brain; C-Reactive Protein; Cognitive Dysfunction; Female; Humans; Image Processing, Computer-Assisted; Interleukin-6; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Peptide Fragments | 2012 |
Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal.
Topics: Acetylation; Acetylcysteine; Acrolein; Aldehydes; Alzheimer Disease; Amidohydrolases; Aminooxyacetic Acid; Animals; Cerebral Cortex; Enzyme Inhibitors; Male; Neurons; Parkinson Disease; Rats; Rats, Wistar | 2012 |
Acrolein induces Alzheimer's disease-like pathologies in vitro and in vivo.
Topics: Acrolein; ADAM Proteins; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Brain; Cell Line; Cell Survival; Cognition; Disintegrins; Immunohistochemistry; Mice; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms | 2013 |
Acrolein-sequestering ability of endogenous dipeptides: characterization of carnosine and homocarnosine/acrolein adducts by electrospray ionization tandem mass spectrometry.
Topics: Acrolein; Alzheimer Disease; Carnosine; Cytotoxins; Molecular Structure; Spectrometry, Mass, Electrospray Ionization | 2003 |
Acrolein inhibits NADH-linked mitochondrial enzyme activity: implications for Alzheimer's disease.
Topics: Acrolein; Alzheimer Disease; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Ketoglutarate Dehydrogenase Complex; Mitochondria; NAD; Pyruvate Dehydrogenase Complex; Thioctic Acid | 2003 |
Modulation of phospholipid asymmetry in synaptosomal membranes by the lipid peroxidation products, 4-hydroxynonenal and acrolein: implications for Alzheimer's disease.
Topics: Acrolein; Aldehydes; Alzheimer Disease; Animals; Carrier Proteins; Cell Membrane; Cerebral Cortex; Gerbillinae; Lipid Peroxidation; Membrane Proteins; Phospholipid Transfer Proteins; Phospholipids; Synaptosomes | 2004 |
Albumin-bound polyacrolein: implications for Alzheimer's disease.
Topics: Acrolein; Adsorption; Alzheimer Disease; Binding Sites; Biomimetic Materials; Colloids; Humans; Polymers; Protein Binding; Serum Albumin | 2004 |
Analysis of derivatized biogenic aldehydes by LC tandem mass spectrometry.
Topics: Acrolein; Aldehydes; Alzheimer Disease; Biomarkers; Chromatography, Liquid; Humans; Lipid Peroxidation; Tandem Mass Spectrometry; Tissue Distribution | 2005 |
Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease.
Topics: Acrolein; Aged, 80 and over; Aldehydes; Alzheimer Disease; Biomarkers; Brain; Cognition Disorders; Female; Humans; Lipid Peroxidation; Male; Tissue Distribution | 2006 |
Abeta-polyacrolein aggregates: novel mechanism of plastic formation in senile plaques.
Topics: Acrolein; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Biophysics; Biopolymers; Brain; Humans; Peptide Fragments; Peptides; Plaque, Amyloid; Plastics; Polymers; Time Factors | 2005 |
Crotonaldehyde accumulates in glial cells of Alzheimer's disease brain.
Topics: Acrolein; Aged; Aged, 80 and over; Aldehydes; Alzheimer Disease; Astrocytes; Brain; Female; Humans; Lipid Peroxidation; Male; Middle Aged; Neuroglia; Oxidative Stress | 2006 |
Endogenous plastic composite material in the Alzheimer's brain.
Topics: Acrolein; Alzheimer Disease; Amyloid; Biopolymers; Brain Chemistry; Humans; Models, Biological; Oxidation-Reduction; Plaque, Amyloid; Plastics; Polymers | 2006 |
Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease.
Topics: Acrolein; Adult; Aged; Aldehydes; Alzheimer Disease; Antibody Specificity; Biomarkers; Cysteine Proteinase Inhibitors; Cytoskeleton; Female; Humans; Lipid Peroxidation; Male; Middle Aged; Nerve Degeneration; Neurofibrillary Tangles; Neurons; Oxidative Stress | 1999 |
Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures.
Topics: Acrolein; Alzheimer Disease; Animals; Biological Transport, Active; Cells, Cultured; Cerebral Cortex; Glucose; Glutamic Acid; Humans; Lipid Peroxidation; Nerve Degeneration; Neurons; Oxidative Stress; Rats | 2000 |