acriflavine and Laryngeal-Diseases

Ten patients with laryngoscleromatous subglottic stenosis have been treated by local two per cent acriflavine solution by a newly designed technique. Two patients with the fibrotic form of this disease were not cured, but the other eight patients (with the granulomatous form) gained a reasonable airway which enabled them to discard their tracheostomy tubes two months after the start of therapy. Up to the present time, for as long as five months after detubation, no single patient has needed a revision tracheostomy. The overall results of this work encourage a trial of local two per cent acriflavine in cases with granulomatous laryngoscleroma.

Topics: Acriflavine; Adult; Aminoacridines; Female; Granuloma, Laryngeal; Humans; Laryngeal Diseases; Laryngostenosis; Male