Page last updated: 2024-10-22

acridone and Hepatitis C

acridone has been researched along with Hepatitis C in 1 studies

acridone : A member of the class of acridines that is 9,10-dihydroacridine substituted by an oxo group at position 9.

Hepatitis C: INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown.

Research Excerpts

ExcerptRelevanceReference
"We report the synthesis and structure-activity relationship (SAR) of a large series of acridones and acridone-fragment derivatives designed on the basis of the selective antihepatitis C virus (HCV) activity shown by acridone 2, previously studied as a potential antibovine viral diarrhea virus (BVDV) compound."7.75Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor. ( Cecchetti, V; Fravolini, A; Gatto, B; Maga, G; Manfroni, G; Massari, S; Neyts, J; Paeshuyse, J; Tabarrini, O; Zanoli, S, 2009)
"We report the synthesis and structure-activity relationship (SAR) of a large series of acridones and acridone-fragment derivatives designed on the basis of the selective antihepatitis C virus (HCV) activity shown by acridone 2, previously studied as a potential antibovine viral diarrhea virus (BVDV) compound."3.75Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor. ( Cecchetti, V; Fravolini, A; Gatto, B; Maga, G; Manfroni, G; Massari, S; Neyts, J; Paeshuyse, J; Tabarrini, O; Zanoli, S, 2009)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Manfroni, G1
Paeshuyse, J1
Massari, S1
Zanoli, S1
Gatto, B1
Maga, G1
Tabarrini, O1
Cecchetti, V1
Fravolini, A1
Neyts, J1

Other Studies

1 other study available for acridone and Hepatitis C

ArticleYear
Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor.
    Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10

    Topics: Acridines; Acridones; Antiviral Agents; Hepacivirus; Hepatitis C; Humans; RNA Helicases; Structure-A

2009