acridone has been researched along with Astrocytoma in 1 studies
acridone : A member of the class of acridines that is 9,10-dihydroacridine substituted by an oxo group at position 9.
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| " N-Substituted phenoxazine and related acridone and benzoxazine derivatives were synthesized and optimized with regard to their potency to inhibit ATP-induced calcium influx in 1321N1 astrocytoma cells stably transfected with the human P2X4 receptor." | 3.78 | N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists. ( Abdelrahman, A; El-Tayeb, A; Freudendahl, D; Hernandez-Olmos, V; Müller, CE; Weinhausen, S, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hernandez-Olmos, V | 1 |
| Abdelrahman, A | 1 |
| El-Tayeb, A | 1 |
| Freudendahl, D | 1 |
| Weinhausen, S | 1 |
| Müller, CE | 1 |
1 other study available for acridone and Astrocytoma
| Article | Year |
|---|---|
N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists.
Topics: Acridines; Acridones; Adenosine Triphosphate; Animals; Astrocytoma; Brain Neoplasms; Calcium; Cells, | 2012 |