Page last updated: 2024-08-21

acridines and Malaria, Falciparum

acridines has been researched along with Malaria, Falciparum in 11 studies

*Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations. [MeSH]

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (9.09)	18.2507
2000's	1 (9.09)	29.6817
2010's	6 (54.55)	24.3611
2020's	3 (27.27)	2.80

Authors

Authors	Studies
Miller, ME; Nelson, SW; Parrott, EE; Singh, R	1
Bouissou, A; Bounaadja, L; Bringmann, P; Girard, YA; Grellier, P; Haas, D; Isola, H; Lanteri, MC; Payrat, JM; Singh, GB; Sow, C	1
Amar El Dusouqui, S; Girard, YA; Grellier, P; Lanteri, MC; Laughhunn, A; Sow, C; Stassinopoulos, A	1
Fonte, M; Gomes, P; Tassi, N; Teixeira, C	1
Cross, RM; Kyle, DE; Lacrue, AN; Maignan, JR; Manetsch, R; Sáenz, FE; Udenze, KO	1
Chauhan, K; Chauhan, PM; Puri, SK; Saxena, JK; Sharma, M; Singh, SV; Srivastava, K; Srivastava, RK	1
Dimopoulos, G; Mlambo, G; Sanders, NG; Sullivan, DJ; Tripathi, AK	1
Batra, S; Biswas, S; Chauhan, BS; Gunjan, S; Pandey, SK; Singh, S; Singh, SK; Srivastava, K; Tripathi, R	1
Hesketh, RL; Rayner, JC; Subramanian, S; Theron, M	1
Ager, A; Andersen, SL; Berman, J; Brown, L; Ellis, W; McGreevy, P; Miller, R; Rossan, R; Schuster, BG	1
Dorn, A; Ellis, WY; Matile, H; Ridley, RG; Scovill, JP; Vennerstrom, JL	1

Reviews

1 review(s) available for acridines and Malaria, Falciparum

Article	Year
Acridine-Based Antimalarials-From the Very First Synthetic Antimalarial to Recent Developments. Molecules (Basel, Switzerland), 2021, Jan-24, Volume: 26, Issue:3 Topics: Acridines; Animals; Antimalarials; Humans; Malaria, Falciparum; Plasmodium falciparum	2021

Other Studies

10 other study(ies) available for acridines and Malaria, Falciparum

Article	Year
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. Journal of biomolecular screening, 2014, Volume: 19, Issue:6 Topics: Antimalarials; Apicoplasts; Chloroplasts; DNA; DNA-Directed DNA Polymerase; Drug Discovery; Exonucleases; Humans; Kinetics; Malaria, Falciparum; Mitochondria; Multienzyme Complexes; Nucleic Acid Synthesis Inhibitors; Peptide Library; Plasmodium falciparum; Protozoan Proteins; Spectrometry, Fluorescence	2014
Robust inactivation of Plasmodium falciparum in red blood cell concentrates using amustaline and glutathione pathogen reduction. Transfusion, 2022, Volume: 62, Issue:5 Topics: Acridines; Erythrocytes; Glutathione; Humans; Malaria, Falciparum; Nitrogen Mustard Compounds; Nucleic Acids; Plasmodium falciparum; Virus Inactivation	2022
Inactivation of Plasmodium falciparum in whole blood using the amustaline and glutathione pathogen reduction technology. Transfusion, 2020, Volume: 60, Issue:4 Topics: Acridines; Blood Safety; Erythrocytes; Glutathione; Humans; Malaria, Falciparum; Microbial Viability; Nitrogen Mustard Compounds; Parasite Load; Parasitemia; Plasmodium falciparum	2020
4-(1H)-Quinolones and 1,2,3,4-Tetrahydroacridin-9(10H)-ones prevent the transmission of Plasmodium falciparum to Anopheles freeborni. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12 Topics: Acridines; Animals; Anopheles; Antimalarials; Female; Humans; Insect Vectors; Life Cycle Stages; Malaria; Malaria, Falciparum; Male; Mice; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Quinolones; Salivary Glands; Structure-Activity Relationship	2013
Design and synthesis of a new class of 4-aminoquinolinyl- and 9-anilinoacridinyl Schiff base hydrazones as potent antimalarial agents. Chemical biology & drug design, 2014, Volume: 84, Issue:2 Topics: Acridines; Aminoquinolines; Animals; Antimalarials; Chlorocebus aethiops; Hydrazones; Malaria, Falciparum; Male; Mice; Plasmodium falciparum; Schiff Bases; Vero Cells	2014
Gametocytocidal screen identifies novel chemical classes with Plasmodium falciparum transmission blocking activity. PloS one, 2014, Volume: 9, Issue:8 Topics: Acridines; Antimalarials; Cells, Cultured; Erythrocytes; Female; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Male; Oocysts; Parasitic Sensitivity Tests; Plasmodium falciparum; Quaternary Ammonium Compounds	2014
Pyrrolidine-Acridine hybrid in Artemisinin-based combination: a pharmacodynamic study. Parasitology, 2016, Volume: 143, Issue:11 Topics: Acridines; Animals; Antimalarials; Artemether; Artemisinins; Drug Resistance, Multiple; Drug Therapy, Combination; Lethal Dose 50; Malaria, Falciparum; Mice; Parasitemia; Plasmodium falciparum; Pyrrolidines	2016
An adaptable two-color flow cytometric assay to quantitate the invasion of erythrocytes by Plasmodium falciparum parasites. Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2010, Volume: 77, Issue:11 Topics: Acridines; Cell Separation; Cells, Cultured; Erythrocytes; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Host-Parasite Interactions; Humans; Malaria, Falciparum; Plasmodium falciparum; Staining and Labeling; Succinimides	2010
Antimalarial activity of WR 243251, a Dihydroacridinedione. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:8 Topics: Acridines; Animals; Antimalarials; Aotus trivirgatus; Drug Resistance; Malaria, Falciparum; Mice; Plasmodium falciparum	1994
Short report: floxacrine analog WR 243251 inhibits hematin polymerization. The American journal of tropical medicine and hygiene, 2001, Volume: 65, Issue:1 Topics: Acridines; Animals; Antimalarials; Hemin; Malaria, Falciparum; Plasmodium falciparum	2001