Page last updated: 2024-08-21

acridines and Leukemia

acridines has been researched along with Leukemia in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199013 (40.63)18.7374
1990's7 (21.88)18.2507
2000's8 (25.00)29.6817
2010's4 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cao, D; Chen, Z; Gao, C; Gao, D; Jiang, Y; Li, S; Liu, F; Liu, H; Wang, Y1
Gao, C; He, S; Jiang, Y; Li, S; Liu, F; Zhang, W1
Bui, T; Ho, RJ; Wu, D; Yang, Z1
Chou, TC; Lee, CH; Shao, LE; Su, TL; Yu, AL; Yu, J1
Imrich, J; Janovec, L; Kozurková, M; Kristian, P; Paulíková, H; Sabolová, D; Suchánová, M; Vantová, Z1
Baczek, T; Ciesielski, T; Koba, M1
Bączek, T; Koba, M1
Baguley, BC; Bridewell, DJ; Finlay, GJ1
Kaufmann, SH; Svingen, PA1
BRAIER, L1
ALTERA, KP; BIJLENGA, G; COHEN, D; FERRIGAN, L1
HIRAKI, K; KOTSUKA, T1
JIPA, G; MICU, D1
KIHATA, M; KITAJIMA, K; KOTSUKA, T; MAKIHATA, T; SASAKI, T; SHINAGAWA, K; SHIRAI, K; TAKAHASHI, Y1
Antonini, I; Borowski, E; Garnier-Suillerot, A; Majewska, E; Rogacka, D; Seksek, O; Tarasiuk, J1
Augustin, E; Konopa, J; Moś-Rompa, A; Skwarska, A; Witkowski, JM1
Bajdichova, M; Jakubikova, J; Paulikova, H; Sabolova, D1
Baguley, BC; Finlay, GJ; Marshall, E; Matthews, JH; Paull, KD1
Baguley, BC; Finlay, GJ1
Baguley, BC; Finlay, GJ; Riou, JF1
Baguley, BC; Davey, MW; Davey, RA; Hargrave, RM; Harvie, RM; Su, GM1
Atwell, GJ; Baguley, BC; Denny, WA; Finlay, GJ; Gamage, SA; Spicer, JA1
Faussat, AM; Marie, JP; Simonin, G; Zhou, DC; Zittoun, R1
Austin, CA; Charlton, P; Padget, K; Stewart, A; Tilby, MJ1
Staĭkova, MA1
Straub, OC; Weiland, F1
Benkert, B; Garbrecht, M; Mertelsmann, R; Neth, R1
Adams, LR; Kamentsky, LA; Melamed, MR; Traganos, F; Zimring, A1
Bolund, L; De Bault, LE; Foley, GE; Gahrton, G; Killander, D; Moloney, WC; Rigler, R; Skarin, A; Wahren, B1
Capizzi, RL; Papirmeister, B; Summers, WP1
Adams, LA; Kamentsky, LA; Melamed, MR; Traganos, F1
Burgio, GR; Genova, R; Severi, F1

Reviews

1 review(s) available for acridines and Leukemia

ArticleYear
[Early changes in the chromatin of mitogen-stimulated lymphocytes (a review of the literature)].
    Eksperimentalna meditsina i morfologiia, 1975, Volume: 14, Issue:2

    Topics: Acridines; Animals; Burkitt Lymphoma; Chromatin; DNA Replication; DNA, Neoplasm; Histones; Humans; Lectins; Leukemia; Lymphocyte Activation; Lymphocytes; Mitogens; Molecular Biology; Oxidative Phosphorylation; RNA; Time Factors

1975

Other Studies

31 other study(ies) available for acridines and Leukemia

ArticleYear
Acridone derivative 8a induces oxidative stress-mediated apoptosis in CCRF-CEM leukemia cells: application of metabolomics in mechanistic studies of antitumor agents.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Acridines; Acridones; Antineoplastic Agents; Apoptosis; Biomarkers; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Discriminant Analysis; Humans; Least-Squares Analysis; Leukemia; Malondialdehyde; Mass Spectrometry; Metabolomics; Mitochondria; Models, Biological; Oxidative Stress; Principal Component Analysis; Reactive Oxygen Species

2013
Synthesis and antiproliferative activity of 2,7-diamino l0-(3,5-dimethoxy)benzyl-9(10H)-acridone derivatives as potent telomeric G-quadruplex DNA ligands.
    Bioorganic chemistry, 2015, Volume: 60

    Topics: Acridines; Acridones; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Proliferation; Diamines; Dimethylamines; DNA; G-Quadruplexes; Humans; Leukemia; Ligands

2015
A novel human multidrug resistance gene MDR1 variant G571A (G191R) modulates cancer drug resistance and efflux transport.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 327, Issue:2

    Topics: Acridines; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Doxorubicin; Drug Resistance, Neoplasm; Genotype; Haplotypes; Humans; Leukemia; Middle Aged; Paclitaxel; Polymorphism, Single Nucleotide; Tetrahydroisoquinolines; Vinblastine

2008
BO-0742, a derivative of AHMA and N-mustard, has selective toxicity to drug sensitive and drug resistant leukemia cells and solid tumors.
    Cancer letters, 2009, Apr-18, Volume: 276, Issue:2

    Topics: Acridines; Aniline Compounds; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Drug Resistance, Neoplasm; Hematopoietic Stem Cells; Humans; Leukemia; Male; Mice; Multidrug Resistance-Associated Proteins; Neoplasms; Nitrogen Mustard Compounds; Xenograft Model Antitumor Assays

2009
Cytotoxic activity of acridin-3,6-diyl dithiourea hydrochlorides in human leukemia line HL-60 and resistant subline HL-60/ADR.
    International journal of biological macromolecules, 2009, Aug-01, Volume: 45, Issue:2

    Topics: Acridines; Antineoplastic Agents; Cell Death; Cell Proliferation; DNA; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Leukemia; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thiourea; Titrimetry; Transition Temperature

2009
Influence of LC retention data on antitumor acridinones' classification evaluated by factor analysis method.
    Combinatorial chemistry & high throughput screening, 2012, Volume: 15, Issue:8

    Topics: Acridines; Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Factor Analysis, Statistical; Leukemia; Lipids; Mice

2012
The evaluation of multivariate adaptive regression splines for the prediction of antitumor activity of acridinone derivatives.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2013, Volume: 9, Issue:8

    Topics: Acridines; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Leukemia; Mice; Models, Molecular; Molecular Structure; Multivariate Analysis; Quantitative Structure-Activity Relationship; Regression Analysis; Software

2013
Topoisomerase I/II selectivity among derivatives of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA).
    Anti-cancer drug design, 2001, Volume: 16, Issue:6

    Topics: Acridines; Antineoplastic Agents; Cell Survival; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Leukemia; Lung Neoplasms; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

2001
Immunoblot analysis and band depletion assays.
    Methods in molecular biology (Clifton, N.J.), 1999, Volume: 94

    Topics: Acridines; Antineoplastic Agents; DNA Adducts; DNA Topoisomerases, Type I; Humans; Immunoblotting; K562 Cells; Leukemia; Pyrazoles; Topotecan

1999
[Antibenzenic substances].
    Le Sang, 1958, Volume: 29, Issue:4

    Topics: Acridines; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphatic Vessels

1958
The use of acridine orange fluorescent staining of peripheral blood cells as a rapid method for the detection of abnormal proliferation of haematopoietic tissues.
    Bulletin of the World Health Organization, 1962, Volume: 26

    Topics: Acridine Orange; Acridines; Blood Cells; Fluorescent Dyes; Hematopoietic System; Humans; Leukemia; Neoplasms; Staining and Labeling

1962
[SYMPOSIUM ON THE CLASSIFICATION OF LEUKEMIA. 5. CLASSIFICATION UNDER THE FLUORESCENCE MICROSCOPE (USING ACRIDINE ORANGE)].
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1963, Volume: 26

    Topics: Acridine Orange; Acridines; Classification; Fluorescence; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Microscopy; Microscopy, Fluorescence

1963
[STUDY OF THE BONE MARROW AND BLOOD CELLS IN LEUCOSES WITH THE AID OF THE FLUORESCENT MICROSCOPE].
    Studii si cercetari de medicina interna, 1963, Volume: 38

    Topics: Acridines; Blood Cells; Bone Marrow; Bone Marrow Examination; DNA; Fluorescence; Fluorescent Dyes; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Microscopy; Microscopy, Fluorescence; RNA

1963
[STUDIES ON VARIOUS HEMATOPOIETIC ORGANS BY FLUOROCHROMINIZED TISSUE CULTURE WITH SPECIAL REFERENCE TO ITS CLINICAL APPLICATION TO THE DIAGNOSIS OF LEUKEMIA].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1964, Aug-10, Volume: 53

    Topics: Acridines; Diagnosis, Differential; Fluorescence; Hematopoietic System; Humans; Leukemia; Microscopy; Microscopy, Fluorescence; Pathology; Research Design

1964
The role of structural factors in the kinetics of cellular uptake of pyrazoloacridines and pyrazolopyrimidoacridines: implications for overcoming multidrug resistance towards leukaemia K562/DOX cells.
    Biochemical pharmacology, 2004, Nov-01, Volume: 68, Issue:9

    Topics: Acridines; Animals; Antineoplastic Agents; Doxorubicin; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Humans; K562 Cells; Kinetics; Leukemia; Mice; NIH 3T3 Cells; Pyrazoles; Tumor Cells, Cultured

2004
Induction of G2/M phase arrest and apoptosis of human leukemia cells by potent antitumor triazoloacridinone C-1305.
    Biochemical pharmacology, 2006, Dec-15, Volume: 72, Issue:12

    Topics: Acridines; Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Cell Division; Cell Line, Tumor; Cell Proliferation; Electrophoresis, Agar Gel; Flow Cytometry; G2 Phase; HL-60 Cells; Humans; In Situ Nick-End Labeling; Intracellular Membranes; Leukemia; Membrane Potentials; Mitochondria; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Triazoles

2006
Comparison of inhibition of murine leukaemia cell growth by 9-isothiocyanatoacridine and its cytosine adduct: involvement of thiols.
    Neoplasma, 2007, Volume: 54, Issue:6

    Topics: Acridines; Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cytosine; DNA Adducts; Erythrocyte Membrane; Flow Cytometry; Glutathione; Humans; Leukemia; Mice; Microscopy, Fluorescence; Sulfhydryl Compounds

2007
In vitro assessment of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide, a DNA-intercalating antitumour drug with reduced sensitivity to multidrug resistance.
    Cancer chemotherapy and pharmacology, 1993, Volume: 31, Issue:5

    Topics: Acridines; Aminoacridines; Antineoplastic Agents; DNA Topoisomerases, Type I; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Intercalating Agents; Leukemia; Melanoma; Tumor Cells, Cultured

1993
Pharmacokinetic/cytokinetic principles in the chemotherapy of solid tumours.
    Clinical and experimental pharmacology & physiology, 1995, Volume: 22, Issue:11

    Topics: Acridines; Antineoplastic Agents; Camptothecin; Cell Cycle; Drug Design; Drug Screening Assays, Antitumor; Humans; Leukemia; Paclitaxel; Tumor Cells, Cultured

1995
From amsacrine to DACA (N-[2-(dimethylamino)ethyl]acridine-4-carboxamide): selectivity for topoisomerases I and II among acridine derivatives.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:4

    Topics: Acridines; Amsacrine; Antineoplastic Agents; DNA; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Leukemia; Tumor Cells, Cultured

1996
The potential of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide to circumvent three multidrug-resistance phenotypes in vitro.
    Cancer chemotherapy and pharmacology, 1997, Volume: 39, Issue:5

    Topics: Acridines; Amsacrine; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Cell Line; Cell Survival; Daunorubicin; Drug Resistance, Multiple; HL-60 Cells; Humans; Idarubicin; Leukemia; Paclitaxel; Phenotype; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Verapamil

1997
Structure-activity relationships for acridine-substituted analogues of the mixed topoisomerase I/II inhibitor N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
    Journal of medicinal chemistry, 1997, Jun-06, Volume: 40, Issue:12

    Topics: Acridines; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Enzyme Inhibitors; Leukemia; Leukemia P388; Lung Neoplasms; Mice; Molecular Structure; Neoplasm Transplantation; Rats; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1997
Effect of the multidrug inhibitor GG918 on drug sensitivity of human leukemic cells.
    Leukemia, 1997, Volume: 11, Issue:9

    Topics: Acridines; Acute Disease; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Membrane Permeability; Drug Resistance, Multiple; Gene Expression; Humans; Idarubicin; Isoquinolines; Leukemia; Mitoxantrone; RNA, Messenger; RNA, Neoplasm; Tetrahydroisoquinolines; Tumor Cells, Cultured; Verapamil

1997
An investigation into the formation of N- [2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 6-[2-(dimethylamino)ethylamino]- 3-hydroxy-7H-indeno[2, 1-C]quinolin-7-one dihydrochloride (TAS-103) stabilised DNA topoisomerase I and II cleavable comple
    Biochemical pharmacology, 2000, Sep-15, Volume: 60, Issue:6

    Topics: Acridines; Aminoquinolines; Antineoplastic Agents; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Neoplasm; Enzyme Stability; Fluorescent Antibody Technique; Humans; Indenes; Leukemia; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

2000
Frequency of surface immunoglobulin bearing blood lymphocytes in cattle affected with bovine leukosis.
    Research in veterinary science, 1975, Volume: 19, Issue:1

    Topics: Acridines; Animals; B-Lymphocytes; Cattle; Cattle Diseases; Cell Separation; Female; Fluorescent Antibody Technique; Leukemia; Lymphocytes; Lymphocytosis; Receptors, Antigen, B-Cell

1975
[The effect of actinomycin d, acridine dyes and related substances on the biosynthesis of nucleic acids in normal and leukemic white blood cells. Comparative investigation in intact cells and in a cell-free system (author's transl)].
    Klinische Wochenschrift, 1975, Aug-15, Volume: 53, Issue:16

    Topics: Acridines; Animals; Cell Membrane; Cell-Free System; Cells, Cultured; Dactinomycin; DNA; DNA-Directed RNA Polymerases; DNA, Neoplasm; Friend murine leukemia virus; Humans; Leukemia; Leukocytes; Mice; Nucleic Acids; Proflavine; RNA; RNA, Neoplasm; Subcellular Fractions; Thymidine; Tritium; Uridine

1975
Acridine orange metachromasia for characterization of leukocytes in leukemia, lymphoma, and other neoplasms.
    Cancer, 1972, Volume: 29, Issue:5

    Topics: Acridines; Breast Neoplasms; Cell Nucleus; Cytoplasm; Fluorescent Dyes; Fluorometry; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mycosis Fungoides; Neoplasms; Photometry; Polycythemia Vera; Staining and Labeling

1972
Influence of cell density on the acridine orange binding to deoxyribonucleoprotein complex in leucocytes from patients with infectious mononucleosis and acute leukaemia.
    Acta haematologica, 1972, Volume: 48, Issue:4

    Topics: Acridines; Acute Disease; Cell Adhesion; Cells, Cultured; Fluorometry; Humans; Infectious Mononucleosis; Leukemia; Leukocytes; Lymphocytes; Nucleoproteins; Protein Binding; Staining and Labeling

1972
Use of the asparagine auxotroph of the L5178Y murine leukemia for the detection of chemical mutagens in vitro and in the host-mediated assay.
    Environmental health perspectives, 1973, Volume: 6

    Topics: Acridines; Alkylating Agents; Animals; Asparagine; Aza Compounds; Cell Line; Cells, Cultured; Clone Cells; Culture Media; Genetic Techniques; Leukemia; Ligases; Male; Mesylates; Mice; Mice, Inbred Strains; Mutagens; Mutation; Nitrogen Mustard Compounds; Nitrosamines; Nitrosoguanidines

1973
Initial observations on instrumental differential blood leukocyte counts during chemotherapy of patients with leukemia.
    European journal of cancer, 1973, Volume: 9, Issue:3

    Topics: Acridines; Adult; Fluorescence; Humans; Leukemia; Leukocyte Count; Male

1973
[Use of fluorescence technics in the study of leukemic cells].
    Minerva pediatrica, 1966, Jun-02, Volume: 18, Issue:18

    Topics: Acridines; Blood Cells; Bone Marrow; Bone Marrow Cells; Fluorescence; Humans; Leukemia; Microscopy, Fluorescence

1966