Page last updated: 2024-08-21

acridines and Hypoxia

acridines has been researched along with Hypoxia in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's1 (12.50)18.2507
2000's5 (62.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dastych, J; Mazerska, Z; Niemira, M1
Brown, JM; Delahoussaye, YM; Denny, WA; Hay, MP; Pruijn, FB1
Anderson, RF; Denny, WA; Harris, TA; Hay, MP1
Iwamoto, A; Sasaki, T; Tsuboi, H; Watanabe, Y1
Belmont, P; Bosson, J; Godet, T; Tiano, M1
Kruglov, AG; Saris, NE; Subbotina, KB1
Burke-Wolin, TM; Gurtner, GH; Michael, JR; Paky, A; Wolin, MS1
Bresler, VM; Domkina, LK; Simanovskiĭ, LN1

Reviews

1 review(s) available for acridines and Hypoxia

ArticleYear
Acridine and acridone derivatives, anticancer properties and synthetic methods: where are we now?
    Anti-cancer agents in medicinal chemistry, 2007, Volume: 7, Issue:2

    Topics: Acridines; Alkaloids; Animals; Antineoplastic Agents; Biological Products; DNA, Neoplasm; Enzyme Inhibitors; Humans; Hypoxia; Protein Kinase Inhibitors; Telomerase; Topoisomerase I Inhibitors

2007

Other Studies

7 other study(ies) available for acridines and Hypoxia

ArticleYear
Pregnane X receptor dependent up-regulation of CYP2C9 and CYP3A4 in tumor cells by antitumor acridine agents, C-1748 and C-1305, selectively diminished under hypoxia.
    Biochemical pharmacology, 2013, Jul-15, Volume: 86, Issue:2

    Topics: Acridines; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Base Sequence; Blotting, Western; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; DNA Primers; Hep G2 Cells; Humans; Hypoxia; Nitracrine; Pregnane X Receptor; Real-Time Polymerase Chain Reaction; Receptors, Steroid; Triazoles; Up-Regulation

2013
Improved potency of the hypoxic cytotoxin tirapazamine by DNA-targeting.
    Biochemical pharmacology, 2003, Jun-01, Volume: 65, Issue:11

    Topics: Acridines; Antineoplastic Agents; Cell Survival; DNA Damage; DNA, Neoplasm; Drug Screening Assays, Antitumor; Free Radicals; HeLa Cells; Humans; Hypoxia; Oxygen; Tirapazamine; Triazines; Tumor Cells, Cultured

2003
Enhanced conversion of DNA radical damage to double strand breaks by 1,2,4-benzotriazine 1,4-dioxides linked to a DNA binder compared to tirapazamine.
    Chemical research in toxicology, 2003, Volume: 16, Issue:11

    Topics: Acridines; Animals; Binding Sites; DNA; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Delivery Systems; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Hypoxia; Plasmids; Pulse Radiolysis; Solutions; Structure-Activity Relationship; Tirapazamine; Triazines; Water

2003
Development of real-time bioradiographic system for functional and metabolic imaging in living brain tissue.
    Brain research, 2006, Mar-10, Volume: 1077, Issue:1

    Topics: Acridines; Animals; Autoradiography; Brain; Fluorodeoxyglucose F18; Gamma Cameras; Glucose; Hypoxia; Luminescent Measurements; Male; Organ Culture Techniques; Radiography; Rats; Rats, Wistar; Superoxides

2006
Redox-cycling compounds can cause the permeabilization of mitochondrial membranes by mechanisms other than ROS production.
    Free radical biology & medicine, 2008, Feb-15, Volume: 44, Issue:4

    Topics: Acridines; Animals; Cell Membrane Permeability; Glutathione; Hypoxia; Male; Mitochondrial Membranes; Mitochondrial Swelling; NAD; Oxidation-Reduction; Rats; Rats, Wistar; Reactive Oxygen Species; Vitamin K 3

2008
Endogenous production of superoxide by rabbit lungs: effects of hypoxia or metabolic inhibitors.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:6

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acridines; Animals; Antimycin A; Cyanides; Hypoxia; In Vitro Techniques; Luminescent Measurements; Lung; Perfusion; Proadifen; Rabbits; Superoxide Dismutase; Superoxides

1993
[Changes in the chromatin structure of hepatocyte nuclei of rats trained to hypoxia].
    Biulleten' eksperimental'noi biologii i meditsiny, 1976, Volume: 81, Issue:3

    Topics: Acridines; Adaptation, Physiological; Animals; Chromatin; Histocytochemistry; Hypoxia; Liver; Male; Rats; Staining and Labeling

1976
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