Page last updated: 2024-08-21

acridines and Disease Models, Animal

acridines has been researched along with Disease Models, Animal in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19905 (15.15)18.7374
1990's4 (12.12)18.2507
2000's6 (18.18)29.6817
2010's15 (45.45)24.3611
2020's3 (9.09)2.80

Authors

AuthorsStudies
Crish, JF; Elmquist, WF; Gampa, G; Hinojosa, AQ; Kenchappa, RS; Kim, M; Luu, A; Mohammad, AS; Parrish, KE; Rosenfeld, SS; Sarkaria, JN; West, R1
Czarnecka, K; Girek, M; Kłosiński, K; Pasieka, Z; Skibiński, R; Szymański, P1
Abdallah, IM; Al-Shami, KM; Kaddoumi, A; Yang, E1
Abreu, MT; Beck, AP; Cao, W; Chen, ML; Cominelli, F; Crynen, G; Delmas, A; Hommes, DW; Izard, T; Jackson, CB; Kayama, H; Kim, SY; Koralov, SB; Lacey, PN; Lorenz, RG; Martinez, GJ; McKevitt, K; Oikonomopoulos, A; Rangarajan, ES; Rodriguez-Palacios, A; Sun, A; Sundrud, MS; Takeda, K1
Endo, S; Kozawa, M; Murakami, H; Muto, M; Tadano, T; Tan-No, K; Tsuchiya, M; Yaoita, F1
Han, G; Hou, J; Li, Y; Liao, Y; Liu, Y; Qian, M; Song, Y; Wang, F; Xu, Z; Zhao, H1
Miura, T; Nishinaka, T; Shimokawa, T; Takama, M; Terada, T; Tsutsui, H; Yamagata, M; Yukimura, T1
Becher, OJ; Chung, AH; Crabtree, D; Elmquist, WF; Halvorson, KG; Hu, G; Mittapalli, RK; Parrish, KE1
Alagappan, M; Denko, NC; Giaccia, AJ; Gupta, A; Hay, MP; Jiang, D; Koong, AC; Kozak, MM; Le, QT; Lum, PY; Niwa, M; Solow-Cordero, DE; Tam, AB1
Atarashi, R; Fuchigami, T; Haratake, M; Kawasaki, M; Kobashi, N; Nakagaki, T; Nakayama, M; Nishida, N; Sano, K; Yoshida, S1
Gold, R; Haghikia, A1
Bauer, U; Elsinghorst, PW; Grosche, J; Gütschow, M; Härtig, W; Hoffmann, A; Kacza, J; Paulke, BR1
Kovalenko, AL; Petrov, AIu; Romantsov, MG; Sologub, TV1
Bankstahl, JP; Bankstahl, M; Erker, T; Kuntner, C; Langer, O; Löscher, W; Mairinger, S; Müller, M; Sauberer, M; Stanek, J; Strommer, S; Wacheck, V; Wanek, T1
Artiukov, AA; Kozlovskaia, ÉP; Krylova, NV; Leonova, GN; Popov, AM1
Agarwal, S; Decker, SA; Donelson, R; Elmquist, WF; Gallardo, JL; Mittapalli, RK; Ohlfest, JR; Pokorny, JL; Santacruz, KS; Sarkaria, JN; Seiler, C; Zellmer, DM1
Kung, AL; Tseng, JC1
Demidik, SN; El'kin, AV; Romantsov, MG; Sukhanov, DS; Vasil'eva, SN; Vinogradova, TI; Vitovskaia, ML; Zabolotnykh, NV1
Fuchigami, T; Haratake, M; Kawasaki, M; Kobashi, N; Nakayama, M1
Barrows, LR; Concepción, GP; Holden, JA; Ireland, CM; Marshall, KM; Matsumoto, SS; Tasdemir, D1
Evseev, VA; Karpova, MN; Vetrilé, LA1
Aksoy, H; Aral, C; Cetinel, S; Gedik, N; Sehirli, O; Sener, G; Yeğen, BC; Yüksel, M1
Dietrich, A; Kroeger, H; Miesel, R; Mitchison, NA; Ulbrich, N1
Loiseau, PM; Nguyen, DX1
Black, PL; McKinnon, KM; Ussery, MA; Wooden, SL1
Chen, IJ; Hang, YS; Huang, WC; Lu, FJ; Sun, JS; Tsuang, YH1
Bredehorn, T; Clausen, M; Duncker, G; Lüllmann-Rauch, R1
Gowan, SM; Harrison, JR; Kelland, LR; Neidle, S; Patterson, L; Read, MA; Valenti, M1
Baron, S; Coppenhaver, DH; Lucia, HL1
Kameyama, T; Nagasaka, M; Yamada, K1
Albin, MS; Bunegin, L; Jannetta, PJ; Massopust, LC1
Stenzel, W1
Rácz, P; Serény, B; Tenner, C1

Reviews

1 review(s) available for acridines and Disease Models, Animal

ArticleYear
[Neuroimmunopathologic aspects of epilepsy].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 2004, Issue:8

    Topics: Acridines; Adolescent; Animals; Antibodies, Anti-Idiotypic; Anticonvulsants; Autoantibodies; Biomedical Research; Child; Cytokines; Disease Models, Animal; Electroencephalography; Epilepsy; Glutamates; Haplorhini; Humans; Immunologic Factors; Immunotherapy; Interferon Inducers; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neuroimmunomodulation; Rabbits; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate

2004

Trials

1 trial(s) available for acridines and Disease Models, Animal

ArticleYear
[Cycloferon in emergency prophylaxis of respiratory viral infections and influenza].
    Klinicheskaia meditsina, 2011, Volume: 89, Issue:1

    Topics: Acridines; Adolescent; Adult; Animals; Disease Models, Animal; Emergencies; Humans; Influenza, Human; Interferon Inducers; Respiratory Tract Infections; Swine; Treatment Outcome; Young Adult

2011

Other Studies

31 other study(ies) available for acridines and Disease Models, Animal

ArticleYear
Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma.
    Scientific reports, 2020, 04-16, Volume: 10, Issue:1

    Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Benzamides; Blood-Brain Barrier; Brain; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Glioblastoma; Humans; Kinesins; Mice; Molecular Targeted Therapy; Neoplasm Invasiveness; Neoplasm Proteins; Quinazolines; Tetrahydroisoquinolines; Xenograft Model Antitumor Assays

2020
Biological assessment of new tetrahydroacridine derivatives with fluorobenzoic moiety in vitro on A549 and HT-29 cell lines and in vivo on animal model.
    Human cell, 2020, Volume: 33, Issue:3

    Topics: Acridines; Animals; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Fluorobenzenes; Humans; Hyaluronoglucosaminidase; Lethal Dose 50; Lung Neoplasms; Mice; Rats; Toxicity Tests

2020
Blood-Brain Barrier Disruption Increases Amyloid-Related Pathology in TgSwDI Mice.
    International journal of molecular sciences, 2021, Jan-27, Volume: 22, Issue:3

    Topics: Acridines; Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Blood-Brain Barrier; Brain; Cell Line; Disease Models, Animal; Immunoglobulin G; Immunohistochemistry; Male; Matrix Metalloproteinase 9; Mice; Mice, Transgenic; NF-kappa B; Signal Transduction; Synapses; Tetrahydroisoquinolines; Tight Junctions

2021
The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids.
    Immunity, 2017, 12-19, Volume: 47, Issue:6

    Topics: Acridines; Adult; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile Acids and Salts; Biological Transport; CD4-Positive T-Lymphocytes; Crohn Disease; Disease Models, Animal; Female; Gene Expression Regulation; Homeodomain Proteins; Homeostasis; Humans; Ileitis; Ileum; Immunity, Mucosal; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Oxidative Stress; Signal Transduction; Tetrahydroisoquinolines

2017
Involvement of peripheral alpha2A adrenoceptor in the acceleration of gastrointestinal transit and abdominal visceral pain induced by intermittent deprivation of REM sleep.
    Physiology & behavior, 2018, 03-15, Volume: 186

    Topics: Acetic Acid; Acridines; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Transit; Ileum; Imidazoles; Irritable Bowel Syndrome; Isoindoles; Male; Mice; Piperazines; Receptors, Adrenergic; Sleep Deprivation; Sleep, REM; Visceral Pain

2018
A near-infrared ratiometric/turn-on fluorescent probe for in vivo imaging of hydrogen peroxide in a murine model of acute inflammation.
    Analytica chimica acta, 2018, Sep-18, Volume: 1024

    Topics: Acridines; Animals; Disease Models, Animal; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Peroxide; Limit of Detection; Linear Models; Mice; Mice, Nude; Molecular Imaging; Perinephritis; Peritoneal Cavity; Spectroscopy, Near-Infrared

2018
Inhibition of α2C-adrenoceptors ameliorates cisplatin-induced acute renal failure in rats.
    European journal of pharmacology, 2018, Nov-05, Volume: 838

    Topics: Acridines; Acute Kidney Injury; Adrenergic alpha-2 Receptor Antagonists; Animals; Apoptosis; Chemokine CCL2; Cisplatin; Disease Models, Animal; Injections, Intraperitoneal; Kidney; Male; Norepinephrine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tumor Necrosis Factor-alpha; Yohimbine

2018
ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B-Driven Brainstem Glioma Model.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:5

    Topics: Acridines; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Blood-Brain Barrier; Brain Stem Neoplasms; Cell Line, Tumor; Dasatinib; Disease Models, Animal; Drug Synergism; Gene Expression; Glioma; Humans; Mice; Mice, Knockout; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Tetrahydroisoquinolines; Treatment Outcome; Xenograft Model Antitumor Assays

2016
Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:9

    Topics: Acridines; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cluster Analysis; Disease Models, Animal; Drug Discovery; Drug Screening Assays, Antitumor; Endoribonucleases; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; High-Throughput Screening Assays; Humans; Mice; Multiple Myeloma; Protein Serine-Threonine Kinases; Signal Transduction; X-Box Binding Protein 1; Xenograft Model Antitumor Assays

2016
Development of radioiodinated acridine derivatives for in vivo imaging of prion deposits in the brain.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Acridines; Administration, Intravenous; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Iodine Radioisotopes; Mice; Molecular Imaging; Molecular Structure; Prion Diseases; Structure-Activity Relationship; Tissue Distribution

2017
Quinpramine: revival of old anti-inflammatory principles in multiple sclerosis?
    Experimental neurology, 2009, Volume: 217, Issue:2

    Topics: Acridines; Animals; Anti-Inflammatory Agents; Benzylamines; Cholesterol; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Humans; Immunological Synapses; Immunosuppression Therapy; Immunosuppressive Agents; Mice; Multiple Sclerosis; Treatment Outcome

2009
In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a fluorescent acetylcholinesterase inhibitor released from nanoparticles.
    The European journal of neuroscience, 2010, Volume: 31, Issue:1

    Topics: Acridines; Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Cholinesterase Inhibitors; Chromones; Disease Models, Animal; Drug Delivery Systems; Enbucrilate; Fluorescent Dyes; Hippocampus; Humans; Mice; Mice, Transgenic; Nanoparticles; Plaque, Amyloid; Polymethacrylic Acids; Polystyrenes; Presenilin-1; tau Proteins

2010
A comparative small-animal PET evaluation of [11C]tariquidar, [11C]elacridar and (R)-[11C]verapamil for detection of P-glycoprotein-expressing murine breast cancer.
    European journal of nuclear medicine and molecular imaging, 2012, Volume: 39, Issue:1

    Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Breast Neoplasms; Carbon Radioisotopes; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Resistance, Neoplasm; Feasibility Studies; Female; Gene Expression Regulation, Neoplastic; Mice; Phenotype; Positron-Emission Tomography; Quinolines; Tetrahydroisoquinolines; Verapamil

2012
[Investigation of luromarin efficacy on mice with experimental tick-borne encephalitis].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2011, Volume: 56, Issue:7-8

    Topics: Acridines; Animals; Antiviral Agents; Caffeic Acids; Disease Models, Animal; Drug Therapy, Combination; Encephalitis Viruses, Tick-Borne; Encephalitis, Tick-Borne; Luteolin; Mice; Ribavirin; Rosmarinic Acid; Virus Replication; Zosteraceae

2011
Active efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:10

    Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Dasatinib; Disease Models, Animal; Endothelium, Vascular; Glioblastoma; Humans; Mice; Mice, Knockout; Molecular Targeted Therapy; Oncogenes; Permeability; Pyrimidines; Signal Transduction; Survival Analysis; Tetrahydroisoquinolines; Thiazoles; Tight Junctions; Tissue Distribution; Treatment Outcome; Xenograft Model Antitumor Assays

2012
In vivo imaging of inflammatory phagocytes.
    Chemistry & biology, 2012, Sep-21, Volume: 19, Issue:9

    Topics: Acridines; Animals; Disease Models, Animal; Fluorescent Dyes; Inflammation; Luminescent Measurements; Luminol; Macrophages; Mice; NADPH Oxidases; Neutrophils; Peroxidase; Phagocytes

2012
[An experimental study of the efficiency of cycloferon in the complex chemotherapy of generalized drug-resistant tuberculosis].
    Eksperimental'naia i klinicheskaia farmakologiia, 2012, Volume: 75, Issue:9

    Topics: Acridines; Animals; Disease Models, Animal; Drug Therapy, Combination; Interferon Inducers; Lung; Male; Mice; Mycobacterium tuberculosis; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2012
Synthesis and biological evaluation of radioiodinated quinacrine-based derivatives for SPECT imaging of Aβ plaques.
    European journal of medicinal chemistry, 2013, Volume: 60

    Topics: Acridines; Amyloid beta-Peptides; Animals; Brain; Disease Models, Animal; Female; Iodine Radioisotopes; Mice; Mice, Inbred Strains; Mice, Transgenic; Molecular Structure; Myocardial Perfusion Imaging; Quinacrine

2013
The anti-neoplastic and novel topoisomerase II-mediated cytotoxicity of neoamphimedine, a marine pyridoacridine.
    Biochemical pharmacology, 2003, Aug-01, Volume: 66, Issue:3

    Topics: Acridines; Animals; Antineoplastic Agents; Cell Division; Disease Models, Animal; DNA; DNA Topoisomerases, Type II; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Phenanthrolines; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2003
Erdosteine prevents colonic inflammation through its antioxidant and free radical scavenging activities.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:9

    Topics: Acridines; Animals; Antioxidants; Colitis; Collagen; Colon; Disease Models, Animal; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Expectorants; Female; Free Radical Scavengers; Glutathione; Luminescence; Luminol; Malondialdehyde; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Thioglycolates; Thiophenes; Trinitrobenzenesulfonic Acid

2007
Assessment of collagen type II induced arthritis in mice by whole blood chemiluminescence.
    Autoimmunity, 1994, Volume: 19, Issue:3

    Topics: Acridines; Animals; Arthritis, Rheumatoid; Autoimmune Diseases; Cattle; Collagen; Crosses, Genetic; Disease Models, Animal; Drug Evaluation, Preclinical; Genetic Predisposition to Disease; Haplotypes; Luminescent Measurements; Male; Mice; Mice, Inbred DBA; Reproducibility of Results; Respiratory Burst

1994
Plasmodium berghei mouse model: antimalarial activity of new alkaloid salts and of thiosemicarbazone and acridine derivatives.
    Tropical medicine & international health : TM & IH, 1996, Volume: 1, Issue:3

    Topics: Acridines; Alkaloids; Animals; Antimalarials; Cinchona Alkaloids; Disease Models, Animal; Female; Malaria; Mice; Mice, Inbred Strains; Plasmodium berghei; Quinine; Resorcinols; Thiosemicarbazones

1996
Antiviral activity of biological response modifiers in a murine model of AIDS. Requirement for augmentation of natural killer cell activity and synergy with oral AZT.
    International journal of immunopharmacology, 1996, Volume: 18, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Acridines; Animals; Antibodies; Antiviral Agents; Asialoglycoproteins; Disease Models, Animal; Drug Synergism; Female; G(M1) Ganglioside; Glucans; Guanosine; Immunologic Factors; In Vitro Techniques; Killer Cells, Natural; Lymphocyte Depletion; Mice; Mice, Inbred BALB C; Poly I-C; Poly U; Pyran Copolymer; Rabbits; Rauscher Virus; Specific Pathogen-Free Organisms; Viral Plaque Assay; Zidovudine

1996
An ultra-weak chemiluminescence study on oxidative stress in rabbits following acute thermal injury.
    Burns : journal of the International Society for Burn Injuries, 1998, Volume: 24, Issue:3

    Topics: Acridines; Acute Disease; Animals; Burns; Disease Models, Animal; Free Radical Scavengers; Indicators and Reagents; Kidney; Liver; Luminescent Measurements; Luminol; Lung; Muscle, Skeletal; Myocardium; Oxidative Stress; Rabbits

1998
Morphological and functional changes due to drug-induced lysosomal storage of sulphated glycosaminoglycans in the rat retina.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2001, Volume: 239, Issue:10

    Topics: Acridines; Adjuvants, Immunologic; Animals; Cytoplasm; Disease Models, Animal; Electroretinography; Female; Glycosaminoglycans; Lysosomes; Microscopy, Fluorescence; Mucopolysaccharidoses; Pigment Epithelium of Eye; Rats; Rats, Wistar; Retina; Retinal Diseases; Vacuoles

2001
A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity.
    Molecular pharmacology, 2002, Volume: 61, Issue:5

    Topics: Acridines; Animals; Antineoplastic Agents; Cell Division; Disease Models, Animal; DNA; G-Quadruplexes; Humans; Immunocompromised Host; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Telomerase; Treatment Outcome; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2002
Arenavirus infection in the guinea pig model: antiviral therapy with recombinant interferon-alpha, the immunomodulator CL246,738 and ribavirin.
    Antiviral research, 1989, Volume: 12, Issue:5-6

    Topics: Acridines; Adjuvants, Immunologic; Animals; Antiviral Agents; Arenaviridae Infections; Disease Models, Animal; Female; Guinea Pigs; Interferon Type I; Male; Precipitin Tests; Recombinant Proteins; Ribavirin; Ribonucleosides

1989
Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice.
    Neuropharmacology, 1985, Volume: 24, Issue:4

    Topics: Acridines; Amitriptyline; Animals; Antidepressive Agents; Depressive Disorder; Desipramine; Diphenhydramine; Disease Models, Animal; Electroshock; Ethanol; Humans; Imipramine; Male; Maprotiline; Mianserin; Mice; Motor Activity; Nialamide; Pargyline; Tranylcypromine

1985
Ketamine-induced postanesthetic delirium attenuated by tetrahydroaminoacridine.
    Experimental neurology, 1974, Volume: 44, Issue:1

    Topics: Acridines; Analysis of Variance; Anesthesia, Intravenous; Animals; Delirium; Disease Models, Animal; Dogs; Evaluation Studies as Topic; Humans; Ketamine

1974
[On the genetics of pathogenicity for mucosa of dysentery bacilli].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abt. Medizinisch-hygienische Bakteriologie, Virusforschung und Parasitologie. Originale, 1971, Volume: 216, Issue:1

    Topics: Acridines; Agar; Animals; Blood; Conjugation, Genetic; Disease Models, Animal; Escherichia coli; Genes; Genetics, Microbial; Glucose; Guinea Pigs; Hybridization, Genetic; Keratoconjunctivitis; Mucous Membrane; Sheep; Shigella; Species Specificity; Urinary Bladder Diseases; Urinary Tract Infections; Virulence

1971
Immunogenicity of living attenuated shigellae.
    Acta microbiologica Academiae Scientiarum Hungaricae, 1971, Volume: 18, Issue:4

    Topics: Acridines; Animals; Bacterial Vaccines; Conjunctiva; Disease Models, Animal; Dysentery, Bacillary; Genetic Variation; Guinea Pigs; Keratoconjunctivitis; Mutagens; Mutation; Shigella flexneri; Vaccines, Attenuated; Virulence

1971