acridines has been researched along with Colorectal Cancer in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Batista, LM; da Silva, PM; de Andrade, CCN; de Lourdes Assunção Araújo de Azevedo, F; de Moura, RO; de Sousa, VM; Duarte, SS; Ferreira, RC; Gomes, JNS; Gonçalves, JCR; Gouveia, RG; Keesen, TSL; Lisboa, TMH; Silva, DKF; Sobral, MV | 1 |
| Czarnecka, K; Girek, M; Kłosiński, K; Pasieka, Z; Skibiński, R; Szymański, P | 1 |
| Artuso, S; Biroccio, A; Cingolani, C; Hummersone, M; Iachettini, S; Leonetti, C; Porru, M; Rizzo, A; Salvati, E; Stevens, M; Zizza, P | 1 |
| Hirt, BV; Laughton, CA; Preston, SP; Wattis, JA | 1 |
| Bowling, MK; Chen, TL; Donehower, RC; Grochow, LB; Kaufmann, SH; Lubejko, BG; Noe, DA; Rowinsky, EK; Sartorious, SE | 1 |
| LoRusso, P; Philip, PA; Shields, AF; Zalupski, MM | 1 |
| Brock, CS; Cunningham, VJ; Harte, RJ; Jones, T; Matthews, JC; Meikle, SR; Price, P; Wells, P | 1 |
| Chandler, LH; de Bruijn, P; Jewell, RC; Loos, WJ; Nooter, K; Paul, EM; Planting, AS; Sparreboom, A; van der Burg, ME; van der Gaast, A; Verweij, J; Wissel, PS | 1 |
| Caponigro, F; de Balincourt, C; Dittrich, C; Duffaud, F; Fumoleau, P; Lacombe, D; Paz Ares, L; Schellens, JH; Sorensen, JB | 1 |
| Dickinson, A; Halcrow, P; Hales, J; Harris, AL; Lawrence, GF; Lennard, TW; McDonald, M; Shenton, BK; Taylor, RM; Wolstencroft, R | 1 |
4 trial(s) available for acridines and Colorectal Cancer
| Article | Year |
|---|---|
Phase I and pharmacologic studies of pyrazoloacridine, a novel DNA intercalating agent, on single-dosing and multiple-dosing schedules.
Topics: Acridines; Adult; Aged; Antineoplastic Agents; Central Nervous System; Colorectal Neoplasms; DNA, Neoplasm; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Intercalating Agents; Male; Middle Aged; Neutropenia; Ovarian Neoplasms; Pyrazoles; Remission Induction; Uterine Cervical Neoplasms | 1995 |
Phase II study of pyrazoloacridine in patients with advanced colorectal carcinoma.
Topics: Acridines; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma; Colorectal Neoplasms; Drug Administration Schedule; Female; Humans; Leukopenia; Male; Middle Aged; Pyrazoles; Safety; Treatment Outcome | 1997 |
Clinical pharmacokinetics of doxorubicin in combination with GF120918, a potent inhibitor of MDR1 P-glycoprotein.
Topics: Acridines; Adult; Aged; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Platelets; Colorectal Neoplasms; Cross-Over Studies; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Humans; Isoquinolines; Male; Middle Aged; Neutrophils; Tetrahydroisoquinolines; Time Factors | 1999 |
Phase II study of XR 5000, an inhibitor of topoisomerases I and II, in advanced colorectal cancer.
Topics: Acridines; Adult; Aged; Antineoplastic Agents; Colorectal Neoplasms; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Middle Aged; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Treatment Outcome | 2002 |
6 other study(ies) available for acridines and Colorectal Cancer
| Article | Year |
|---|---|
Apoptotic and antioxidant effects in HCT-116 colorectal carcinoma cells by a spiro-acridine compound, AMTAC-06.
Topics: Acridines; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; HCT116 Cells; Humans; Leukocytes, Mononuclear; Reactive Oxygen Species; Spiro Compounds | 2022 |
Biological assessment of new tetrahydroacridine derivatives with fluorobenzoic moiety in vitro on A549 and HT-29 cell lines and in vivo on animal model.
Topics: Acridines; Animals; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Fluorobenzenes; Humans; Hyaluronoglucosaminidase; Lethal Dose 50; Lung Neoplasms; Mice; Rats; Toxicity Tests | 2020 |
Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities.
Topics: Acridines; Antineoplastic Agents; Cell Proliferation; Colorectal Neoplasms; DNA Damage; Dose-Response Relationship, Drug; Drug Design; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; HT29 Cells; Humans; Ligands; Membrane Potentials; Molecular Structure; Receptors, Adrenergic, beta-2; Structure-Activity Relationship; Telomere | 2014 |
The effects of a telomere destabilizing agent on cancer cell-cycle dynamics--integrated modelling and experiments.
Topics: Acridines; Antineoplastic Agents; Cell Cycle; Cell Death; Colorectal Neoplasms; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; HCT116 Cells; Humans; Models, Biological; Telomerase; Telomere | 2012 |
Pharmacokinetic assessment of novel anti-cancer drugs using spectral analysis and positron emission tomography: a feasibility study.
Topics: Acridines; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine; Feasibility Studies; Female; Fluorouracil; Glioma; Humans; Middle Aged; Spectrum Analysis; Temozolomide; Tomography, Emission-Computed | 1998 |
A phase I study of immunostimulation and toxicity in patients with colorectal carcinoma using the immunomodulator 3,6-bis(2-piperidinoethoxy) acridine trihydrochloride (CL 246738).
Topics: Acridines; Adenocarcinoma; Adjuvants, Immunologic; Adult; Aged; Antineoplastic Agents; Colorectal Neoplasms; Drug Evaluation; Female; Humans; Male; Middle Aged | 1989 |