acridines has been researched along with Colonic Neoplasms in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (13.33) | 18.7374 |
| 1990's | 11 (36.67) | 18.2507 |
| 2000's | 7 (23.33) | 29.6817 |
| 2010's | 7 (23.33) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bagiński, M; Bartoszewski, R; Dąbrowska, AM; Filip-Psurska, B; Gawrońska, M; Krzymiński, K; Milczarek, M; Moszyńska, A; Psurski, M; Świtalska, M; Wietrzyk, J | 1 |
| Fu, W; Li, R; Li, X; Liu, S; Lu, X; Meng, X; Wang, Y; Yang, X; Zhang, L; Zhang, N; Zhao, Y; Zhu, WG | 1 |
| Blanco-Aparicio, C; Llanos, S; Megias, D; Morgado-Palacin, L; Pastor, J; Serrano, M; Urbano-Cuadrado, M | 1 |
| Chen, K; Chu, BZ; Gao, CM; Jiang, YY; Li, B; Li, LL; Liu, F; Shen, ZF; Sun, QS | 1 |
| Fukumura, T; Hatori, A; Kawamura, K; Nengaki, N; Ogawa, M; Wakisaka, H; Yamasaki, T; Yanamoto, K; Yoshida, Y; Yui, J; Zhang, MR | 1 |
| Beretta, G; Biroccio, A; D'Angelo, C; Franceschin, M; Gilson, E; Leonetti, C; Orlandi, A; Passeri, D; Pisano, C; Porru, M; Rizzo, A; Salvati, E; Stevens, MF; Zunino, F; Zupi, G | 1 |
| Bhardwaj, A; Huang, Z; Kaur, J; Knaus, EE; Sharma, SK; Wuest, F | 1 |
| Barros, FW; Bezerra, DP; Burbano, RR; Cavalcanti, BC; Costa-Lotufo, LV; de Lima, Mdo C; Ferreira, PM; Galdino, SL; Guecheva, TN; Henriques, JA; Moraes, MO; Pessoa, C; Pitta, Ida R; Pitta, MG; Silva, TG | 1 |
| Berlinck, RG; Bugni, TS; Ferreira, AG; Ireland, CM; Magalhães, A; Moreira Da Rocha, R; Torres, YR | 1 |
| Incles, CM; Kelland, LR; Neidle, S; Schultes, CM | 1 |
| Chang, HO; Chang, LS; Chou, SY; Hsu, SC; Lee, YJ; Wang, SS; Yin, WK | 1 |
| Baguley, BC; Marshall, E; Zhuang, L | 1 |
| Capps, DB; Corbett, TH; Horwitz, JP; Leopold, WR; Massova, I; Sebolt-Leopold, JS; Wiese, TE; Wozniak, AJ | 1 |
| Guziec, FS; Guziec, LJ; Kohn, KW; O'Connor, PM; Orr, A | 1 |
| Du Vignaud, P; Grand-Perret, T; Hyafil, F; Vergely, C | 1 |
| Chołody, WM; Konopa, J; Kuśnierczyk, H; Paradziej-Lukowicz, J; Radzikowski, C | 1 |
| Atwell, GJ; Baguley, BC; Denny, WA; Finlay, GJ; Gamage, SA; Spicer, JA | 2 |
| Boratyński, J; Duś, D; Kuśnierczyk, H; Paprocka, M; Radzikowski, C | 1 |
| Baguley, BC; Denny, WA; Finlay, GJ; Graves, DE; Spicer, JA; Velea, L | 1 |
| Anisimov, VN; Kovalenko, AL; Popovich, IG; Zabezhinski, MA | 1 |
| Budd, GT; Bukowski, RM; Ganapathi, R; McLain, D; Olencki, T; Peereboom, D; Pelley, R; Rybicki, L; Wood, L | 1 |
| Aktan, AO; Haklar, G; Sayin-Ozveri, E; Yalçin, AS; Yüksel, M | 1 |
| Chen, CM; Lin, FW; Wu, TS | 1 |
| Goldin, A; Houchens, DP; Johnson, RK; Osieka, R | 1 |
| Baguley, BC; Finlay, GJ | 1 |
| Biernat, L; Capps, D; Corbett, TH; Dan, ME; Leopold, WR; LoRusso, P; Polin, L; Werbel, LM; Wozniak, AJ | 1 |
| Atwell, GJ; Baguley, BC; Denny, WA; Finlay, GJ; Rewcastle, GW | 1 |
| Cone, CD; May, JF; Rounds, DE | 1 |
| Panecka, A | 1 |
1 trial(s) available for acridines and Colonic Neoplasms
| Article | Year |
|---|---|
A phase II pharmacodynamic study of pyrazoloacridine in patients with metastatic colorectal cancer.
Topics: Acridines; Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Female; Humans; Intercalating Agents; Male; Middle Aged; Neoplasm Metastasis; Nervous System Diseases; Neutropenia; Pyrazoles; Rectal Neoplasms | 2000 |
29 other study(ies) available for acridines and Colonic Neoplasms
| Article | Year |
|---|---|
Combined anticancer therapy with imidazoacridinone analogue C-1305 and paclitaxel in human lung and colon cancer xenografts-Modulation of tumour angiogenesis.
Topics: Acridines; Apoptosis; Colonic Neoplasms; Heterografts; Humans; Lung; Lung Neoplasms; Paclitaxel; Triazoles | 2022 |
A novel acridine derivative, LS-1-10 inhibits autophagic degradation and triggers apoptosis in colon cancer cells.
Topics: Acridines; Animals; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Chloroquine; Colonic Neoplasms; Drug Resistance, Neoplasm; Humans; Mice; Proteolysis; Xenograft Model Antitumor Assays | 2017 |
Non-genotoxic activation of p53 through the RPL11-dependent ribosomal stress pathway.
Topics: Acridines; Blotting, Northern; Blotting, Western; Bone Neoplasms; Colonic Neoplasms; DNA Damage; Flow Cytometry; Fluorescent Antibody Technique; High-Throughput Screening Assays; Humans; Immunoprecipitation; Naphthyridines; Osteosarcoma; Pharmaceutical Preparations; Proto-Oncogene Proteins c-mdm2; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Proteins; RNA, Messenger; RNA, Small Interfering; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2014 |
New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway.
Topics: Acridines; Antineoplastic Agents; Apoptosis; Benzimidazoles; Caspases; Cell Line, Tumor; Colon; Colonic Neoplasms; HCT116 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Signal Transduction | 2015 |
PET study on mice bearing human colon adenocarcinoma cells using [11C]GF120918, a dual radioligand for P-glycoprotein and breast cancer resistance protein.
Topics: Acridines; Adenocarcinoma; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Blotting, Western; Caco-2 Cells; Carbon Radioisotopes; Colonic Neoplasms; Dogs; Humans; Ligands; Male; Mice; Neoplasm Proteins; Positron-Emission Tomography; Tetrahydroisoquinolines; Tomography, Emission-Computed, Single-Photon | 2010 |
DNA damage persistence as determinant of tumor sensitivity to the combination of Topo I inhibitors and telomere-targeting agents.
Topics: Acridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Cycle; Cell Survival; Cells, Cultured; Colonic Neoplasms; DNA Damage; Drug Synergism; G-Quadruplexes; HCT116 Cells; HT29 Cells; Humans; Irinotecan; Male; Mice; Mice, Nude; Telomere; Topoisomerase I Inhibitors; Treatment Outcome; Xenograft Model Antitumor Assays | 2011 |
Hybrid fluorescent conjugates of COX-2 inhibitors: search for a COX-2 isozyme imaging cancer biomarker.
Topics: Acridines; Acridones; Biomarkers, Tumor; Celecoxib; Cell Line, Tumor; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Fluorescent Dyes; Humans; Ibuprofen; Microscopy, Confocal; Protein Binding; Pyrazoles; Rhodamines; Structure-Activity Relationship; Sulfonamides | 2013 |
Inhibition of DNA topoisomerase I activity and induction of apoptosis by thiazacridine derivatives.
Topics: Acridines; Apoptosis; Caspases; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Comet Assay; DNA Fragmentation; DNA Topoisomerases, Type I; Humans; Microscopy, Fluorescence; Saccharomyces cerevisiae; Telomerase; Thiazolidinediones | 2013 |
Sebastianines A and B, novel biologically active pyridoacridine alkaloids from the Brazilian ascidian Cystodytes dellechiajei.
Topics: Acridines; Alkaloids; Animals; Antineoplastic Agents; Brazil; Catalysis; Cell Survival; Colonic Neoplasms; Heterocyclic Compounds, 4 or More Rings; Humans; Inhibitory Concentration 50; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pyridines; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Urochordata | 2002 |
Acquired cellular resistance to flavopiridol in a human colon carcinoma cell line involves up-regulation of the telomerase catalytic subunit and telomere elongation. Sensitivity of resistant cells to combination treatment with a telomerase inhibitor.
Topics: Acridines; Antineoplastic Agents; Catalytic Domain; Colonic Neoplasms; Cyclin D1; Cyclin T; Cyclin-Dependent Kinase 9; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA-Binding Proteins; Drug Combinations; Drug Resistance, Neoplasm; Enzyme Inhibitors; Flavonoids; Humans; Piperidines; Telomerase; Telomere; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation | 2003 |
Linker-modified triamine-linked acridine dimers: synthesis and cytotoxicity properties in vitro and in vivo.
Topics: Acridines; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; DNA; Humans; Indicators and Reagents; Intercalating Agents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Mice, Inbred ICR; Mice, SCID; Nitrogen; Plasmids; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2007 |
Experimental solid tumour activity of N-[2-(dimethylamino)ethyl]-acridine-4-carboxamide.
Topics: Acridines; Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Cell Line; Colonic Neoplasms; Humans; Intercalating Agents; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Nude; Regression Analysis; Time Factors; Transplantation, Heterologous | 1995 |
Comparative molecular field analysis of in vitro growth inhibition of L1210 and HCT-8 cells by some pyrazoloacridines.
Topics: Acridines; Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Electrochemistry; Humans; Intercalating Agents; Leukemia L1210; Mice; Models, Molecular; Molecular Structure; Pyrazoles; Structure-Activity Relationship; Tumor Cells, Cultured | 1993 |
Synthesis and DNA-sequence selectivity of a series of mono- and difunctional 9-aminoacridine nitrogen mustards.
Topics: Acridines; Alkylation; Base Sequence; Binding Sites; Colonic Neoplasms; DNA; Guanine; Humans; Intercalating Agents; Mechlorethamine; Molecular Sequence Data; Molecular Structure; Nitrogen Mustard Compounds; Tumor Cells, Cultured | 1994 |
In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative.
Topics: Acridines; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; Cell Survival; Colonic Neoplasms; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Female; Humans; Isoquinolines; Leukemia P388; Mice; Mice, Inbred DBA; Ovary; Tetrahydroisoquinolines; Tumor Cells, Cultured | 1993 |
Experimental antitumor activity and toxicity of the selected triazolo- and imidazoacridinones.
Topics: Acridines; Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Female; Imidazoles; Lethal Dose 50; Leukemia P388; Male; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasm Transplantation; Triazoles | 1994 |
Structure-activity relationships for acridine-substituted analogues of the mixed topoisomerase I/II inhibitor N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
Topics: Acridines; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Enzyme Inhibitors; Leukemia; Leukemia P388; Lung Neoplasms; Mice; Molecular Structure; Neoplasm Transplantation; Rats; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1997 |
Conjugation of the monoclonal antibody 17-1A with the nitroacridine compound C921 with the poly-L-lysine as an intermediate agent.
Topics: Acridines; Adenocarcinoma; Antibodies, Monoclonal; Antibody Specificity; Colonic Neoplasms; Flow Cytometry; Humans; Immunotoxins; Melanoma; Polylysine; Tumor Cells, Cultured | 1997 |
5,7-Disubstituted analogues of the mixed topoisomerase I/II poison N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA): DNA binding and patterns of cytotoxicity.
Topics: Acridines; Animals; Colonic Neoplasms; DNA, Neoplasm; Enzyme Inhibitors; Humans; Intercalating Agents; Magnetic Resonance Spectroscopy; Mice; Neoplasm Transplantation; Time Factors; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1999 |
Structure-activity relationships for substituted bis(acridine-4-carboxamides): a new class of anticancer agents.
Topics: Acridines; Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Mice; Mutation; Neoplasm Transplantation; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1999 |
Inhibitory effect of synthetic interferon inductor Cycloferone on 1,2-dimethylhydrazine-induced colon carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Acridines; Adenocarcinoma; Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Colonic Neoplasms; Female; Interferon Inducers; Rats; Sarcoma | 2000 |
Different kinds of reactive oxygen and nitrogen species were detected in colon and breast tumors.
Topics: Acridines; Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Female; Humans; Hypochlorous Acid; Luminescent Measurements; Luminol; Male; Middle Aged; Nitrates; Nitric Oxide; Reactive Oxygen Species | 2001 |
Constituents of the root bark of Severinia buxifolia collected in Hainan.
Topics: Acridines; Acridones; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Colonic Neoplasms; Crystallography, X-Ray; Drugs, Chinese Herbal; Humans; KB Cells; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Roots; Plants, Medicinal; Taiwan; Triterpenes; Tumor Cells, Cultured | 2001 |
Chemotherapy of human colon cancer xenografts in athymic nude mice.
Topics: Acridines; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Aspartic Acid; Carcinoma; Cell Line; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Lomustine; Male; Maytansine; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Streptozocin; Transplantation, Heterologous; Triazines | 1977 |
Potentiation by phenylbisbenzimidazoles of cytotoxicity of anticancer drugs directed against topoisomerase II.
Topics: Acridines; Amsacrine; Animals; Antineoplastic Agents; Benzimidazoles; Bisbenzimidazole; Colonic Neoplasms; Doxorubicin; Drug Synergism; Etoposide; Fluorescent Dyes; Leukemia L1210; Lung Neoplasms; Melanoma; Mice; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1990 |
Antitumor efficacy of PD115934 (NSC 366140) against solid tumors of mice.
Topics: Acridines; Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Intraductal, Noninfiltrating; Cell Survival; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Pancreatic Neoplasms; Pyrazoles; Tumor Cells, Cultured | 1990 |
Potential antitumor agents. 47. 3'-Methylamino analogues of amsacrine with in vivo solid tumor activity.
Topics: Acridines; Aminoacridines; Amsacrine; Animals; Cell Line; Chemical Phenomena; Chemistry; Colonic Neoplasms; DNA; Humans; Leukemia L1210; Leukemia P388; Mice; Solubility; Structure-Activity Relationship | 1986 |
Intercellular transfer of toxic components after laser irradiation.
Topics: Acid Phosphatase; Acridines; Adenocarcinoma; Argon; Cell Line; Cell Nucleus; Colonic Neoplasms; Culture Techniques; Cytoplasm; Female; Fibroma; Histocytochemistry; Hot Temperature; Lasers; Lysosomes; Microscopy, Phase-Contrast; Neoplasms; Photosensitivity Disorders; Radiation Effects; Staining and Labeling; Uterine Neoplasms | 1971 |
[The significance of cytological examinations under fluorescence microscope for diagnosis and surgical treatment of maignant tumours. I].
Topics: Acridines; Breast Neoplasms; Colonic Neoplasms; Cytodiagnosis; Esophageal Neoplasms; Humans; Lung Neoplasms; Microscopy, Fluorescence; Neoplasms; Stomach Neoplasms | 1970 |