acridines has been researched along with Astrocytoma, Grade IV in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Antoccia, A; Berardinelli, F; Buccarelli, M; D'Alessandris, QG; Doria, F; Grande, S; Luciani, AM; Pallini, R; Palma, A; Pirota, V; Ricci-Vitiani, L; Rosi, A; Triveri, A | 1 |
| Crish, JF; Elmquist, WF; Gampa, G; Hinojosa, AQ; Kenchappa, RS; Kim, M; Luu, A; Mohammad, AS; Parrish, KE; Rosenfeld, SS; Sarkaria, JN; West, R | 1 |
| Antoccia, A; Berardinelli, F; Buccarelli, M; di Masi, A; Leone, S; Mancuso, M; Muoio, D; Pallini, R; Ricci-Vitiani, L; Tanori, M | 1 |
| Allhenn, D; Béduneau, A; Lamprecht, A; Neumann, D; Pellequer, Y | 1 |
| Beijnen, JH; Beumer, JH; Buil, LC; Christner, SM; de Gooijer, MC; Lin, F; Roig, EM; van Tellingen, O; Würdinger, T | 1 |
| Antoccia, A; Berardinelli, F; Sgura, A; Siteni, S; Stevens, MF; Tanzarella, C | 1 |
| Bakken, K; Elmquist, WF; Mittapalli, RK; Parrish, KE; Pokorny, J; Sarkaria, JN | 1 |
| Chen, Y; Cheng, Y; Li, Y; Liu, X; Ma, C; Wu, X; Xu, S; Yu, Z; Zhao, G; Zhou, G | 1 |
| Agarwal, S; Decker, SA; Donelson, R; Elmquist, WF; Gallardo, JL; Mittapalli, RK; Ohlfest, JR; Pokorny, JL; Santacruz, KS; Sarkaria, JN; Seiler, C; Zellmer, DM | 1 |
| Anderson, J; Augustus, TM; Bierbach, U; Hess, SM | 1 |
| Anderson, JG; Bierbach, U; Hess, SM | 1 |
| Bernhardt, G; Buschauer, A; Gartner, M; Giannis, A; Gross, D; Müller, C; Sarli, V | 1 |
| Adjei, AA; Buckwalter, CA; Budihardjo, II; Donehower, RC; Grochow, LB; Kaufmann, SH; Kottke, TJ; Rowinsky, EK; Svingen, PA | 1 |
| Campone, M; Coudert, B; de Balincourt, C; de Jonge, M; Dittrich, C; Fumoleau, P; Lacombe, D; Rampling, R; Sorio, R; Twelves, C; Van den Bent, M | 1 |
1 trial(s) available for acridines and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Phase II study of XR5000 (DACA) administered as a 120-h infusion in patients with recurrent glioblastoma multiforme.
Topics: Acridines; Adult; Aged; Brain Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Glioblastoma; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Survival Analysis; Treatment Outcome | 2002 |
13 other study(ies) available for acridines and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Effects of the Combined Treatment with a G-Quadruplex-Stabilizing Ligand and Photon Beams on Glioblastoma Stem-like Cells: A Magnetic Resonance Study.
Topics: Acridines; Brain Neoplasms; Cell Survival; G-Quadruplexes; Glioblastoma; Humans; Ligands; Magnetic Resonance Spectroscopy; Neoplastic Stem Cells; Photons; Radiation Tolerance; Radiation-Sensitizing Agents | 2021 |
Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Benzamides; Blood-Brain Barrier; Brain; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Glioblastoma; Humans; Kinesins; Mice; Molecular Targeted Therapy; Neoplasm Invasiveness; Neoplasm Proteins; Quinazolines; Tetrahydroisoquinolines; Xenograft Model Antitumor Assays | 2020 |
G-quadruplex ligand RHPS4 radiosensitizes glioblastoma xenograft in vivo through a differential targeting of bulky differentiated- and stem-cancer cells.
Topics: Acridines; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Checkpoint Kinase 1; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Mice; Neoplastic Stem Cells; Rad51 Recombinase; Radiation-Sensitizing Agents; Xenograft Model Antitumor Assays | 2019 |
A "drug cocktail" delivered by microspheres for the local treatment of rat glioblastoma.
Topics: Acridines; Animals; Antineoplastic Agents, Phytogenic; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Carriers; Etoposide; Glioblastoma; Lactic Acid; Male; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrazoles; Rats; Rats, Inbred F344; Sulfonamides; Tetrahydroisoquinolines | 2013 |
ABCB1, ABCG2, and PTEN determine the response of glioblastoma to temozolomide and ABT-888 therapy.
Topics: Acridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzimidazoles; Blood-Brain Barrier; Blotting, Western; Brain; Cell Line, Tumor; Dacarbazine; Dogs; Glioblastoma; Humans; Immunohistochemistry; Kaplan-Meier Estimate; LLC-PK1 Cells; Madin Darby Canine Kidney Cells; Metabolic Clearance Rate; Mice, Knockout; Mice, Nude; PTEN Phosphohydrolase; Swine; Temozolomide; Tetrahydroisoquinolines; Treatment Outcome | 2014 |
The G-quadruplex-stabilising agent RHPS4 induces telomeric dysfunction and enhances radiosensitivity in glioblastoma cells.
Topics: Acridines; Cell Line; Cell Line, Tumor; Cell Proliferation; DNA Repair; G-Quadruplexes; Glioblastoma; Histones; Humans; Phosphorylation; Radiation Tolerance; Radiation-Sensitizing Agents; Telomerase; Telomere | 2015 |
Efflux transporters at the blood-brain barrier limit delivery and efficacy of cyclin-dependent kinase 4/6 inhibitor palbociclib (PD-0332991) in an orthotopic brain tumor model.
Topics: Acridines; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Dogs; Drug Resistance, Neoplasm; Drug Synergism; Female; Glioblastoma; Heterografts; Madin Darby Canine Kidney Cells; Male; Mice; Mice, Knockout; Mice, Nude; Neoplasm Transplantation; Piperazines; Pyridines; Tetrahydroisoquinolines | 2015 |
Telomere targeting with a novel G-quadruplex-interactive ligand BRACO-19 induces T-loop disassembly and telomerase displacement in human glioblastoma cells.
Topics: Acridines; Apoptosis; Cell Proliferation; Cytostatic Agents; DNA Damage; G-Quadruplexes; Glioblastoma; Humans; Telomerase; Telomere; Tumor Cells, Cultured | 2016 |
Active efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Dasatinib; Disease Models, Animal; Endothelium, Vascular; Glioblastoma; Humans; Mice; Mice, Knockout; Molecular Targeted Therapy; Oncogenes; Permeability; Pyrimidines; Signal Transduction; Survival Analysis; Tetrahydroisoquinolines; Thiazoles; Tight Junctions; Tissue Distribution; Treatment Outcome; Xenograft Model Antitumor Assays | 2012 |
Bis(acridinylthiourea)platinum(II) complexes: synthesis, DNA affinity, and biological activity in glioblastoma cells.
Topics: Acridines; Animals; Antineoplastic Agents; Cattle; Cell Survival; DNA; Glioblastoma; Humans; Intercalating Agents; Organoplatinum Compounds; Spectrophotometry, Ultraviolet; Thiourea; Tumor Cells, Cultured | 2003 |
A non-crosslinking platinum-acridine hybrid agent shows enhanced cytotoxicity compared to clinical BCNU and cisplatin in glioblastoma cells.
Topics: Acridines; Animals; Carmustine; Caspase 3; Caspases; Cell Line; Cisplatin; Cross-Linking Reagents; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glioblastoma; Inhibitory Concentration 50; Organoplatinum Compounds; Platinum | 2005 |
Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.
Topics: Acridines; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Flow Cytometry; Fluoresceins; Glioblastoma; Humans; Insecticides; Kinesins; Molecular Structure; Paclitaxel; Pyrimidines; Quinazolines; Rotenone; Spindle Apparatus; Tetrahydroisoquinolines; Thiones; Time Factors; Tubulin; Tubulin Modulators; Vinblastine | 2007 |
Cytotoxic synergy between pyrazoloacridine (NSC 366140) and cisplatin in vitro: inhibition of platinum-DNA adduct removal.
Topics: Acridines; Adenocarcinoma; Animals; Antineoplastic Agents; Cell Survival; CHO Cells; Cisplatin; Cricetinae; DNA Adducts; Drug Synergism; Glioblastoma; Humans; Intercalating Agents; Intestinal Neoplasms; Pyrazoles; Tumor Cells, Cultured | 1997 |